CS408591A3 - Substituted 3,4-dihydro-2h-benzopyranes, process of their preparation,their use and pharmaceuticals based on said compounds - Google Patents

Substituted 3,4-dihydro-2h-benzopyranes, process of their preparation,their use and pharmaceuticals based on said compounds Download PDF

Info

Publication number
CS408591A3
CS408591A3 CS914085A CS408591A CS408591A3 CS 408591 A3 CS408591 A3 CS 408591A3 CS 914085 A CS914085 A CS 914085A CS 408591 A CS408591 A CS 408591A CS 408591 A3 CS408591 A3 CS 408591A3
Authority
CS
Czechoslovakia
Prior art keywords
dihydro
dimethyl
formula
compound
benzo
Prior art date
Application number
CS914085A
Other languages
Czech (cs)
English (en)
Inventor
Heinrich C Englert
Hans-Jochen Lang
Dieter Mania
Bernward Scholkens
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of CS408591A3 publication Critical patent/CS408591A3/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
CS914085A 1987-02-04 1991-12-27 Substituted 3,4-dihydro-2h-benzopyranes, process of their preparation,their use and pharmaceuticals based on said compounds CS408591A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873703227 DE3703227A1 (de) 1987-02-04 1987-02-04 Substituierte 3,4-dihydro-2h-benzopyrane, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen

Publications (1)

Publication Number Publication Date
CS408591A3 true CS408591A3 (en) 1992-10-14

Family

ID=6320136

Family Applications (1)

Application Number Title Priority Date Filing Date
CS914085A CS408591A3 (en) 1987-02-04 1991-12-27 Substituted 3,4-dihydro-2h-benzopyranes, process of their preparation,their use and pharmaceuticals based on said compounds

Country Status (21)

Country Link
US (1) US4999371A (fr)
EP (1) EP0277612B1 (fr)
JP (1) JPH0730072B2 (fr)
KR (1) KR960005151B1 (fr)
AR (1) AR243180A1 (fr)
AT (1) ATE92060T1 (fr)
AU (1) AU604525B2 (fr)
CA (1) CA1335504C (fr)
CS (1) CS408591A3 (fr)
DE (2) DE3703227A1 (fr)
DK (1) DK166279C (fr)
ES (1) ES2058149T3 (fr)
FI (1) FI90979C (fr)
HU (1) HU205107B (fr)
IE (1) IE62220B1 (fr)
IL (1) IL85290A (fr)
NO (1) NO169963C (fr)
NZ (1) NZ223383A (fr)
PH (1) PH24326A (fr)
PT (1) PT86690B (fr)
ZA (1) ZA88754B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5387587A (en) * 1986-12-23 1995-02-07 Merck Patent Gesellschaft Mit Beschrankter Haftung Chroman derivatives
DE3881714D1 (de) * 1987-02-04 1993-07-22 Hoechst Ag Alkylsubstituierte n-benzopyranyllactame, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen.
US5284838A (en) * 1987-06-23 1994-02-08 Elf Sanofi Use of 2,2-dimethylchroman-3-ol derivatives in the treatment of asthma
GB8800199D0 (en) * 1988-01-06 1988-02-10 Beecham Group Plc Pharmaceutical preparation
DE3823533A1 (de) * 1988-07-12 1990-02-08 Beiersdorf Ag Substituierte 4-heterocyclyl-2h-benzo(b)pyrane, verfahren und 4-hydroxy-3-brom-, 3,4-oxiranyl-3,4-dehydro-2h-benzo(b)pyrane als zwischenprodukte zu ihrer herstellung, sowie sie enthaltende pharmazeutsche praeparate
DE3824446A1 (de) * 1988-07-19 1990-01-25 Hoechst Ag, 6230 Frankfurt Verwendung substituierter 3,4-dihydro-2h-benzopyrane als heilmittel gegen obstruktive funktionsstoerungen der lunge und/oder stoerungen der ableitenden harnwege
US5364878A (en) * 1988-07-19 1994-11-15 Hoechst Aktiengesellschaft Use of substituted 3,4-dihydro-2H-benzopyrans as remedies for obstructive functional disorders of the lungs
DE3827532A1 (de) * 1988-08-13 1990-03-01 Hoechst Ag 6-aroyl-substituierte 3,4-dihydro-2h-benzopyrane, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen
DE3837809A1 (de) * 1988-11-08 1990-05-10 Merck Patent Gmbh Tetralinderivate
GB8924373D0 (en) * 1989-10-30 1989-12-20 Beecham Group Plc Novel compounds
JP2575226B2 (ja) * 1990-05-11 1997-01-22 吉富製薬株式会社 光学活性な３，４−ジヒドロ−３，４−エポキシ−２ｈ−１ベンゾピラン化合物の製造法およびその合成中間体
TW244350B (fr) * 1991-12-14 1995-04-01 Hoechst Ag
JP3502403B2 (ja) * 1991-12-16 2004-03-02 アベンティス ファーマ株式会社 骨吸収抑制剤
HUT72741A (en) * 1992-12-19 1996-05-28 Alkaloida Vegyeszeti Gyar Method for producing benzopyrane derivatives and pharmaceutical compositions containing them
GB9316111D0 (en) * 1993-08-04 1993-09-22 Pfizer Ltd Benzopyrans
KR100691836B1 (ko) * 2005-03-30 2007-03-12 한국화학연구원 2,2' 위치에 이중치환된 6-아미노술포닐 벤조피란 유도체 및 그를 유효성분으로 함유하는 항우울제

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ183551A (en) * 1976-04-02 1978-09-20 Beecham Group Ltd Aminochromanols and pharmaceutical compositions containingthem
DE3064286D1 (en) * 1979-09-28 1983-08-25 Beecham Group Plc Chromanol derivatives, a process for their preparation and a pharmaceutical composition comprising them
DE3274350D1 (en) * 1981-09-25 1987-01-08 Beecham Group Plc Pharmaceutically active benzopyran compounds
EP0091748B1 (fr) * 1982-04-08 1986-06-18 Beecham Group Plc Antihypertensifs benzopyranols
EP0107423B1 (fr) * 1982-10-19 1986-07-23 Beecham Group Plc Chromanes et chromènes
GB8308062D0 (en) * 1983-03-24 1983-05-05 Beecham Group Plc Active compounds
GB8419516D0 (en) * 1984-07-31 1984-09-05 Beecham Group Plc Treatment
GB8521857D0 (en) * 1985-09-03 1985-10-09 Beecham Group Plc Active compounds
DE3881714D1 (de) * 1987-02-04 1993-07-22 Hoechst Ag Alkylsubstituierte n-benzopyranyllactame, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen.

Also Published As

Publication number Publication date
JPH0730072B2 (ja) 1995-04-05
EP0277612A3 (en) 1990-04-25
CA1335504C (fr) 1995-05-09
AU1122688A (en) 1988-08-11
NO880473L (no) 1988-08-05
FI880467A (fi) 1988-08-05
FI880467A0 (fi) 1988-02-02
DK166279C (da) 1993-08-23
EP0277612B1 (fr) 1993-07-28
JPS63201182A (ja) 1988-08-19
ZA88754B (en) 1988-08-04
IE880294L (en) 1988-08-04
DK55088A (da) 1988-08-05
NO880473D0 (no) 1988-02-03
FI90979B (fi) 1994-01-14
IL85290A (en) 1994-10-07
AR243180A1 (es) 1993-07-30
DK166279B (da) 1993-03-29
KR880009958A (ko) 1988-10-06
NO169963B (no) 1992-05-18
PT86690B (pt) 1992-04-30
PT86690A (pt) 1988-03-01
IL85290A0 (en) 1988-07-31
EP0277612A2 (fr) 1988-08-10
IE62220B1 (en) 1995-01-11
HUT50166A (en) 1989-12-28
DE3882544D1 (de) 1993-09-02
US4999371A (en) 1991-03-12
ES2058149T3 (es) 1994-11-01
KR960005151B1 (ko) 1996-04-22
DK55088D0 (da) 1988-02-03
PH24326A (en) 1990-05-29
HU205107B (en) 1992-03-30
ATE92060T1 (de) 1993-08-15
FI90979C (fi) 1994-04-25
NO169963C (no) 1992-08-26
AU604525B2 (en) 1990-12-20
NZ223383A (en) 1990-01-29
DE3703227A1 (de) 1988-08-18

Similar Documents

Publication Publication Date Title
CS408591A3 (en) Substituted 3,4-dihydro-2h-benzopyranes, process of their preparation,their use and pharmaceuticals based on said compounds
US5306819A (en) Certain aryl a cycloalkyl fused imidazopyrazinols; and new class of GABA brain receptor ligands
HUT65427A (en) Process for preparation of azaheterocyclyl-methyl-chromane derivatives and pharmaceuticals compositions containing them
JPS5993076A (ja) 新規クロマン類及びクロメン類、これらを製造する方法及びこれらを含有する医薬組成物
NZ208169A (en) N-substituted-4-amino-chromans and-chromenes and pharmaceutical compositions
HU207311B (en) Process for producing chromane derivatives and pharmaceutical compositions containing them
US6451809B2 (en) Oxo-pyridoimidazole-carboxamides: GABA brain receptor ligands
PL166192B1 (pl) Sposób wytwarzania nowych pochodnych cyjanoguanidyny PL PL
PT98019A (pt) Processo para a preparacao de composicoes farmaceuticas contendo derivados e benzopiran e analogos heterociclicos dos mesmos utilizados como agentes anti-isquemicos
JPH0566953B2 (fr)
EP0068171B1 (fr) Dérivés de dihydropyridine
HU195653B (en) Process for preparing dihydro-pyridyl-benzothiophene and thienopyridine derivatives
JP2009509927A (ja) カリウムチャンネル開口剤としての新規ベンゾピラン誘導体
IL91015A (en) Pharmaceutical preparations for the treatment of obstructive functional disorders of the lungs and / or urinary tract containing 3,4-dihydro-H 2 -benzopyranes
US5278158A (en) Oxazinobenzazole compounds
KR940004059B1 (ko) 비시클로락탐유도체
CZ282172B6 (cs) Benzpyranové analogy pro léčení úzkosti, mánie, deprese nebo symptomů po přerušení podávání drog nebo léčiv, způsob přípravy těchto sloučenin, jejich použití a farmaceutický prostředek obsahující tyto sloučeniny
KR870001511B1 (ko) 벤조옥사졸-및 벤조티아졸아민 유도체의 제조방법
CN115141169A (zh) 一种萜内酯衍生物及其在医药上的应用
JPH05503938A (ja) 医薬組成物
WO2000010973A2 (fr) Oxo-pyridoimidazole-carboxamides: ligands du recepteur cerebral gaba
IE920835A1 (en) Certain imidazoquinoxalines; a new class of gaba brain receptor ligands