CS241025B2 - Method of fussed pyrimidine-4-ons' dihalogenated derivatives production - Google Patents

Method of fussed pyrimidine-4-ons' dihalogenated derivatives production Download PDF

Info

Publication number
CS241025B2
CS241025B2 CS803258A CS325880A CS241025B2 CS 241025 B2 CS241025 B2 CS 241025B2 CS 803258 A CS803258 A CS 803258A CS 325880 A CS325880 A CS 325880A CS 241025 B2 CS241025 B2 CS 241025B2
Authority
CS
Czechoslovakia
Prior art keywords
formula
compound
hydrogen
compounds
group
Prior art date
Application number
CS803258A
Other languages
Czech (cs)
English (en)
Other versions
CS325880A2 (en
Inventor
Istvan Hermecz
Tibor Breining
Lelle Vasvari
Agnes Horvath
Zoltan Meszaros
Istvan Bitter
Jozsef Koekoese
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of CS325880A2 publication Critical patent/CS325880A2/cs
Publication of CS241025B2 publication Critical patent/CS241025B2/cs

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B62/00Reactive dyes, i.e. dyes which form covalent bonds with the substrates or which polymerise with themselves

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
CS803258A 1979-05-11 1980-05-08 Method of fussed pyrimidine-4-ons' dihalogenated derivatives production CS241025B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU79CI1932A HU179443B (en) 1979-05-11 1979-05-11 Process for producing substituted geminal dihalogeno-derivatives of pyrido-square bracket-1,2-a-square closed-pyrimidines,pyrrolo-square bracket-1,2-a-square bracket closed-pyrimidines and pyrimido-square bracket-1,2,-a-square bracket closed-asepines

Publications (2)

Publication Number Publication Date
CS325880A2 CS325880A2 (en) 1985-06-13
CS241025B2 true CS241025B2 (en) 1986-03-13

Family

ID=10994747

Family Applications (1)

Application Number Title Priority Date Filing Date
CS803258A CS241025B2 (en) 1979-05-11 1980-05-08 Method of fussed pyrimidine-4-ons' dihalogenated derivatives production

Country Status (24)

Country Link
JP (1) JPS5615286A (sv)
AT (1) AT377261B (sv)
BE (1) BE883217A (sv)
CA (1) CA1141379A (sv)
CH (1) CH646971A5 (sv)
CS (1) CS241025B2 (sv)
DD (1) DD150605A5 (sv)
DE (1) DE3017564A1 (sv)
DK (1) DK204680A (sv)
ES (1) ES491896A0 (sv)
FI (1) FI68825C (sv)
FR (1) FR2456101A1 (sv)
GB (1) GB2051048B (sv)
GR (1) GR68518B (sv)
HU (1) HU179443B (sv)
IL (1) IL59967A (sv)
IT (1) IT1133085B (sv)
LU (1) LU82437A1 (sv)
NL (1) NL8002678A (sv)
NO (1) NO152607C (sv)
PL (1) PL124035B1 (sv)
PT (1) PT71213A (sv)
SE (1) SE441747B (sv)
SU (1) SU1151210A3 (sv)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU178453B (en) * 1979-05-11 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 9-hydrazino-4-oxo-6,7,8,9-tetrahydro-4h-p-pyrido-square bracket-1,2-a-square bracket closed-pyrimidine derivatives
US4395549A (en) 1981-10-02 1983-07-26 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. 6-Hydrazono-pyrido[2,1-b] quinazoline-11 ones
ES8501397A1 (es) * 1982-08-05 1984-11-16 Erba Farmitalia "procedimiento para preparar derivados de quinazolina"
US5158952A (en) * 1988-11-07 1992-10-27 Janssen Pharmaceutica N.V. 3-[2-[4-(6-fluoro-1,2-benzisoxozol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9 tetrahydro-9-hydroxy-2-methyl-4H-pyrido [1,2-a]pyrimidin-4-one, compositions and method of use
UA72189C2 (uk) 1997-11-17 2005-02-15 Янссен Фармацевтика Н.В. Фармацевтична композиція, що містить водну суспензію субмікронних ефірів 9-гідроксирисперидон жирних кислот

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT286990B (de) * 1966-11-02 1971-01-11 Chinoin Gyogyszer Es Vegyeszet Verfahren zur Herstellung von neuen Homopyrimidazol-Derivaten sowie von deren Salzen
HU178496B (en) * 1977-12-29 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 6,7,8,9-tetrahydro-4h-pyrido/1,2-a/pyrimidine derivatives with antiallergic activity

Also Published As

Publication number Publication date
NO152607B (no) 1985-07-15
BE883217A (fr) 1980-09-01
DD150605A5 (de) 1981-09-09
IT8067719A0 (it) 1980-05-09
CS325880A2 (en) 1985-06-13
GR68518B (sv) 1982-01-11
PL224163A1 (sv) 1981-02-13
NL8002678A (nl) 1980-11-13
GB2051048B (en) 1983-01-19
ATA247580A (de) 1984-07-15
DK204680A (da) 1980-11-12
NO801378L (no) 1980-11-12
LU82437A1 (fr) 1980-07-31
FR2456101A1 (fr) 1980-12-05
ES8102570A1 (es) 1981-02-16
FR2456101B1 (sv) 1985-04-05
AT377261B (de) 1985-02-25
PL124035B1 (en) 1982-12-31
CH646971A5 (de) 1984-12-28
FI68825C (fi) 1985-11-11
CA1141379A (en) 1983-02-15
SU1151210A3 (ru) 1985-04-15
FI68825B (fi) 1985-07-31
PT71213A (en) 1980-06-01
NO152607C (no) 1985-10-23
JPS5615286A (en) 1981-02-14
SE8003479L (sv) 1980-11-12
IT1133085B (it) 1986-07-09
HU179443B (en) 1982-10-28
DE3017564A1 (de) 1980-11-13
FI801512A (fi) 1980-11-12
IL59967A0 (en) 1980-07-31
SE441747B (sv) 1985-11-04
GB2051048A (en) 1981-01-14
ES491896A0 (es) 1981-02-16
IL59967A (en) 1984-05-31

Similar Documents

Publication Publication Date Title
US7786304B2 (en) Process for the preparation of eszopiclone
MXPA96003091A (en) Cloropirimid intermediaries
NO314456B1 (no) Fremgangsmåter og mellomprodukter nyttige for å fremstille antifolater
CS241025B2 (en) Method of fussed pyrimidine-4-ons' dihalogenated derivatives production
CS198297B2 (en) Method of producing derivatives of urea
JPH01316379A (ja) 縮合複素環類の製造方法
JPH08503224A (ja) β−カルボリンの新規製造方法
JP2000504352A (ja) ハロアルコキシ基を含有するピロロ[3,2―c]キノリン誘導体及び薬学的に許容されるその塩
JPS61225183A (ja) β−カルボリンの製造法
IE52422B1 (en) 4-aroylimidazol-2-ones
SU1024007A3 (ru) Способ получени производных пиридо/1,2-а/пиримидина или их солей с щелочными металлами или их оптических изомеров
JPH0227994B2 (sv)
NO882085L (no) Cyklobutenmellomprodukt.
JPS63290849A (ja) 芳香族化合物のヨウ素化剤及びそれを用いたヨウ素化方法
JPH02233642A (ja) D(+)‐2‐(4‐アセチルフェノキシ)プロピオン酸エステル類の製造方法
US5283332A (en) 2-amino(fluoroalkoxy)pyrimidines and the preparation thereof
US4271073A (en) 6-Substituted-9-(2-hydroxyethyl)-1,2,3,4-tetrahydro carbazol-1-one
CS207610B2 (en) Method of preparation of the 5-alcylsulfonylbarbiturate acids and 5-alcenylsulphonylbarbiturate acid and the derivates thereof
JPH06329640A (ja) 2−(ベンズイミダゾール−2−イル)−1,3−ジアミノプロパンの薬理学的に活性な誘導体
JP3376481B2 (ja) ヘキサヒドロピリダジンの製造法
WO1995021828A1 (fr) Procede de production de derives de l'hexahydropyridazine et de l'hexahydropyridazine-1,2-dicarboxylate
JP2009532508A (ja) クロピドグレルの改良された調製方法
CZ154999A3 (cs) Způsob výroby nafthyridinových sloučenin a nové meziprodukty pro tuto výrobu
JPS63112580A (ja) テトラヒドロピリド〔2,3−d〕ピリミジン誘導体
JPS63225366A (ja) 1,2,4−トリアジン系化合物