FI68825C - Geminala dihalogenderivat av kondenserade pyrimidin-4-oner vilka aer mellanprodukter vid framstaellning av terapeutiskt anaendbara 9-aminopyrido(1,2-a)pyrimidin- och 9-hydratsono- 6,,8,9-tetrahydro-4h-pyrido(1,2-a)pyrimidinderivat - Google Patents

Geminala dihalogenderivat av kondenserade pyrimidin-4-oner vilka aer mellanprodukter vid framstaellning av terapeutiskt anaendbara 9-aminopyrido(1,2-a)pyrimidin- och 9-hydratsono- 6,,8,9-tetrahydro-4h-pyrido(1,2-a)pyrimidinderivat Download PDF

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Publication number
FI68825C
FI68825C FI801512A FI801512A FI68825C FI 68825 C FI68825 C FI 68825C FI 801512 A FI801512 A FI 801512A FI 801512 A FI801512 A FI 801512A FI 68825 C FI68825 C FI 68825C
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FI
Finland
Prior art keywords
tetrahydro
pyrimidin
pyrido
methyl
pyrimidine
Prior art date
Application number
FI801512A
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English (en)
Finnish (fi)
Other versions
FI68825B (fi
FI801512A (fi
Inventor
Istvan Hermecz
Tibor Breining
Nee Debreczy Lelle Vasvari
Agnes Horvath
Zoltan Meszaros
Istvan Bitter
Jozsef Koekoesi
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
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Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of FI801512A publication Critical patent/FI801512A/fi
Application granted granted Critical
Publication of FI68825B publication Critical patent/FI68825B/fi
Publication of FI68825C publication Critical patent/FI68825C/fi

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B62/00—Reactive dyes, i.e. dyes which form covalent bonds with the substrates or which polymerise with themselves

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
FI801512A 1979-05-11 1980-05-09 Geminala dihalogenderivat av kondenserade pyrimidin-4-oner vilka aer mellanprodukter vid framstaellning av terapeutiskt anaendbara 9-aminopyrido(1,2-a)pyrimidin- och 9-hydratsono- 6,,8,9-tetrahydro-4h-pyrido(1,2-a)pyrimidinderivat FI68825C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU79CI1932A HU179443B (en) 1979-05-11 1979-05-11 Process for producing substituted geminal dihalogeno-derivatives of pyrido-square bracket-1,2-a-square closed-pyrimidines,pyrrolo-square bracket-1,2-a-square bracket closed-pyrimidines and pyrimido-square bracket-1,2,-a-square bracket closed-asepines
HUCI001932 1979-05-11

Publications (3)

Publication Number Publication Date
FI801512A FI801512A (fi) 1980-11-12
FI68825B FI68825B (fi) 1985-07-31
FI68825C true FI68825C (fi) 1985-11-11

Family

ID=10994747

Family Applications (1)

Application Number Title Priority Date Filing Date
FI801512A FI68825C (fi) 1979-05-11 1980-05-09 Geminala dihalogenderivat av kondenserade pyrimidin-4-oner vilka aer mellanprodukter vid framstaellning av terapeutiskt anaendbara 9-aminopyrido(1,2-a)pyrimidin- och 9-hydratsono- 6,,8,9-tetrahydro-4h-pyrido(1,2-a)pyrimidinderivat

Country Status (24)

Country Link
JP (1) JPS5615286A (sv)
AT (1) AT377261B (sv)
BE (1) BE883217A (sv)
CA (1) CA1141379A (sv)
CH (1) CH646971A5 (sv)
CS (1) CS241025B2 (sv)
DD (1) DD150605A5 (sv)
DE (1) DE3017564A1 (sv)
DK (1) DK204680A (sv)
ES (1) ES491896A0 (sv)
FI (1) FI68825C (sv)
FR (1) FR2456101A1 (sv)
GB (1) GB2051048B (sv)
GR (1) GR68518B (sv)
HU (1) HU179443B (sv)
IL (1) IL59967A (sv)
IT (1) IT1133085B (sv)
LU (1) LU82437A1 (sv)
NL (1) NL8002678A (sv)
NO (1) NO152607C (sv)
PL (1) PL124035B1 (sv)
PT (1) PT71213A (sv)
SE (1) SE441747B (sv)
SU (1) SU1151210A3 (sv)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU178453B (en) * 1979-05-11 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 9-hydrazino-4-oxo-6,7,8,9-tetrahydro-4h-p-pyrido-square bracket-1,2-a-square bracket closed-pyrimidine derivatives
US4395549A (en) 1981-10-02 1983-07-26 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. 6-Hydrazono-pyrido[2,1-b] quinazoline-11 ones
ES8501397A1 (es) * 1982-08-05 1984-11-16 Erba Farmitalia "procedimiento para preparar derivados de quinazolina"
US5158952A (en) * 1988-11-07 1992-10-27 Janssen Pharmaceutica N.V. 3-[2-[4-(6-fluoro-1,2-benzisoxozol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9 tetrahydro-9-hydroxy-2-methyl-4H-pyrido [1,2-a]pyrimidin-4-one, compositions and method of use
UA72189C2 (uk) 1997-11-17 2005-02-15 Янссен Фармацевтика Н.В. Фармацевтична композиція, що містить водну суспензію субмікронних ефірів 9-гідроксирисперидон жирних кислот

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT286990B (de) * 1966-11-02 1971-01-11 Chinoin Gyogyszer Es Vegyeszet Verfahren zur Herstellung von neuen Homopyrimidazol-Derivaten sowie von deren Salzen
HU178496B (en) * 1977-12-29 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 6,7,8,9-tetrahydro-4h-pyrido/1,2-a/pyrimidine derivatives with antiallergic activity

Also Published As

Publication number Publication date
NO152607B (no) 1985-07-15
BE883217A (fr) 1980-09-01
DD150605A5 (de) 1981-09-09
IT8067719A0 (it) 1980-05-09
CS325880A2 (en) 1985-06-13
GR68518B (sv) 1982-01-11
PL224163A1 (sv) 1981-02-13
NL8002678A (nl) 1980-11-13
GB2051048B (en) 1983-01-19
ATA247580A (de) 1984-07-15
CS241025B2 (en) 1986-03-13
DK204680A (da) 1980-11-12
NO801378L (no) 1980-11-12
LU82437A1 (fr) 1980-07-31
FR2456101A1 (fr) 1980-12-05
ES8102570A1 (es) 1981-02-16
FR2456101B1 (sv) 1985-04-05
AT377261B (de) 1985-02-25
PL124035B1 (en) 1982-12-31
CH646971A5 (de) 1984-12-28
CA1141379A (en) 1983-02-15
SU1151210A3 (ru) 1985-04-15
FI68825B (fi) 1985-07-31
PT71213A (en) 1980-06-01
NO152607C (no) 1985-10-23
JPS5615286A (en) 1981-02-14
SE8003479L (sv) 1980-11-12
IT1133085B (it) 1986-07-09
HU179443B (en) 1982-10-28
DE3017564A1 (de) 1980-11-13
FI801512A (fi) 1980-11-12
IL59967A0 (en) 1980-07-31
SE441747B (sv) 1985-11-04
GB2051048A (en) 1981-01-14
ES491896A0 (es) 1981-02-16
IL59967A (en) 1984-05-31

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Owner name: CHINOIN GYOGUSZER ES VEGYESZETI TERMEKEK