LU82437A1 - Derives dihalogenes gemines de composes de pyrimidine-one 4 condenses,procede de preparation et compositions pharmaceutiques contenant ceux-ci - Google Patents

Derives dihalogenes gemines de composes de pyrimidine-one 4 condenses,procede de preparation et compositions pharmaceutiques contenant ceux-ci Download PDF

Info

Publication number
LU82437A1
LU82437A1 LU82437A LU82437A LU82437A1 LU 82437 A1 LU82437 A1 LU 82437A1 LU 82437 A LU82437 A LU 82437A LU 82437 A LU82437 A LU 82437A LU 82437 A1 LU82437 A1 LU 82437A1
Authority
LU
Luxembourg
Prior art keywords
general formula
compound
acid
pyrido
tetrahydro
Prior art date
Application number
LU82437A
Other languages
English (en)
French (fr)
Inventor
J Koekoesi
I Hermecz
L Vasvari
A Horvath
Z Meszaros
T Breining
I Bitter
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of LU82437A1 publication Critical patent/LU82437A1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B62/00Reactive dyes, i.e. dyes which form covalent bonds with the substrates or which polymerise with themselves

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
LU82437A 1979-05-11 1980-05-09 Derives dihalogenes gemines de composes de pyrimidine-one 4 condenses,procede de preparation et compositions pharmaceutiques contenant ceux-ci LU82437A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU79CI1932A HU179443B (en) 1979-05-11 1979-05-11 Process for producing substituted geminal dihalogeno-derivatives of pyrido-square bracket-1,2-a-square closed-pyrimidines,pyrrolo-square bracket-1,2-a-square bracket closed-pyrimidines and pyrimido-square bracket-1,2,-a-square bracket closed-asepines
HUCI001932 1979-05-11

Publications (1)

Publication Number Publication Date
LU82437A1 true LU82437A1 (fr) 1980-07-31

Family

ID=10994747

Family Applications (1)

Application Number Title Priority Date Filing Date
LU82437A LU82437A1 (fr) 1979-05-11 1980-05-09 Derives dihalogenes gemines de composes de pyrimidine-one 4 condenses,procede de preparation et compositions pharmaceutiques contenant ceux-ci

Country Status (24)

Country Link
JP (1) JPS5615286A (sv)
AT (1) AT377261B (sv)
BE (1) BE883217A (sv)
CA (1) CA1141379A (sv)
CH (1) CH646971A5 (sv)
CS (1) CS241025B2 (sv)
DD (1) DD150605A5 (sv)
DE (1) DE3017564A1 (sv)
DK (1) DK204680A (sv)
ES (1) ES491896A0 (sv)
FI (1) FI68825C (sv)
FR (1) FR2456101A1 (sv)
GB (1) GB2051048B (sv)
GR (1) GR68518B (sv)
HU (1) HU179443B (sv)
IL (1) IL59967A (sv)
IT (1) IT1133085B (sv)
LU (1) LU82437A1 (sv)
NL (1) NL8002678A (sv)
NO (1) NO152607C (sv)
PL (1) PL124035B1 (sv)
PT (1) PT71213A (sv)
SE (1) SE441747B (sv)
SU (1) SU1151210A3 (sv)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU178453B (en) * 1979-05-11 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 9-hydrazino-4-oxo-6,7,8,9-tetrahydro-4h-p-pyrido-square bracket-1,2-a-square bracket closed-pyrimidine derivatives
US4395549A (en) 1981-10-02 1983-07-26 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. 6-Hydrazono-pyrido[2,1-b] quinazoline-11 ones
ES8501397A1 (es) * 1982-08-05 1984-11-16 Erba Farmitalia "procedimiento para preparar derivados de quinazolina"
US5158952A (en) * 1988-11-07 1992-10-27 Janssen Pharmaceutica N.V. 3-[2-[4-(6-fluoro-1,2-benzisoxozol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9 tetrahydro-9-hydroxy-2-methyl-4H-pyrido [1,2-a]pyrimidin-4-one, compositions and method of use
UA72189C2 (uk) 1997-11-17 2005-02-15 Янссен Фармацевтика Н.В. Фармацевтична композиція, що містить водну суспензію субмікронних ефірів 9-гідроксирисперидон жирних кислот

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT286990B (de) * 1966-11-02 1971-01-11 Chinoin Gyogyszer Es Vegyeszet Verfahren zur Herstellung von neuen Homopyrimidazol-Derivaten sowie von deren Salzen
HU178496B (en) * 1977-12-29 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 6,7,8,9-tetrahydro-4h-pyrido/1,2-a/pyrimidine derivatives with antiallergic activity

Also Published As

Publication number Publication date
NO152607B (no) 1985-07-15
BE883217A (fr) 1980-09-01
DD150605A5 (de) 1981-09-09
IT8067719A0 (it) 1980-05-09
CS325880A2 (en) 1985-06-13
GR68518B (sv) 1982-01-11
PL224163A1 (sv) 1981-02-13
NL8002678A (nl) 1980-11-13
GB2051048B (en) 1983-01-19
ATA247580A (de) 1984-07-15
CS241025B2 (en) 1986-03-13
DK204680A (da) 1980-11-12
NO801378L (no) 1980-11-12
FR2456101A1 (fr) 1980-12-05
ES8102570A1 (es) 1981-02-16
FR2456101B1 (sv) 1985-04-05
AT377261B (de) 1985-02-25
PL124035B1 (en) 1982-12-31
CH646971A5 (de) 1984-12-28
FI68825C (fi) 1985-11-11
CA1141379A (en) 1983-02-15
SU1151210A3 (ru) 1985-04-15
FI68825B (fi) 1985-07-31
PT71213A (en) 1980-06-01
NO152607C (no) 1985-10-23
JPS5615286A (en) 1981-02-14
SE8003479L (sv) 1980-11-12
IT1133085B (it) 1986-07-09
HU179443B (en) 1982-10-28
DE3017564A1 (de) 1980-11-13
FI801512A (fi) 1980-11-12
IL59967A0 (en) 1980-07-31
SE441747B (sv) 1985-11-04
GB2051048A (en) 1981-01-14
ES491896A0 (es) 1981-02-16
IL59967A (en) 1984-05-31

Similar Documents

Publication Publication Date Title
EP0011059B1 (fr) Procédé de préparation de la (+,-) vincadifformine et d'autres dérivés pentacycliques apparentés
KR101502322B1 (ko) 순수한 아나스트로졸의 제조방법
JPS6014030B2 (ja) 抗抑うつ症剤の製造方法
LU82437A1 (fr) Derives dihalogenes gemines de composes de pyrimidine-one 4 condenses,procede de preparation et compositions pharmaceutiques contenant ceux-ci
EP0008446B1 (en) Process for the preparation of carbazoles and novel carbazole derivatives utilized therein
EP0500443B1 (fr) Nouvelles phényléthanolamino- et phényléthanolaminométhyl-tétralines, procédé pour leur préparation, intermédiaires dans ce procédé et compositions pharmaceutiques les contenant
FR2510110A1 (sv)
JP3205634B2 (ja) 2−クロロ−5−アルキルアミノメチル−ピリジン類の製造方法
FR2689889A1 (fr) Nouveaux dérivés de perhydroisoindole, et leur préparation.
KR970000685B1 (ko) 5-클로로-3-클로로설포닐-2-티오펜카복실산 에스테르의 제조방법
LU80470A1 (fr) "noveaux derives de 4-animo-2-(piperazin-1-yl ou homopipe-razin-1-yl)-quinazoline, leur procede de production et composition pharmaceutique les contenant.
CH640537A5 (fr) Procede de preparation de 3-exomethylenecepham-sulfoxydes.
JPH0256478A (ja) 2,3,4,5―テトラヒドロ―1―ベンズオキセピン―3,5―ジオン誘導体及びその製法
JPH0227994B2 (sv)
LU86706A1 (fr) Nouveaux derives du benzo(4,5)cyclohepta(1,2-b)thiophene,leur preparation et leur utilisation comme medicaments
US4271073A (en) 6-Substituted-9-(2-hydroxyethyl)-1,2,3,4-tetrahydro carbazol-1-one
CH638210A5 (fr) Ester derive de l'acide quinolopyranne-4-one-2-carboxylique, procede de sa preparation et utilisation de cet ester comme compose actif dans un medicament antiallergique pour le traitement de l'asthme.
FR2472571A1 (fr) Procede pour la preparation de derives d'esters halogeno-vincaminiques et halogeno-apovincaminiques
EP0228356B1 (fr) Nouveaux dérivés d'hydroxy-4 indole, leur procédé de préparation et leur utilisation
JP4374088B2 (ja) 新規な4,4−ジフルオロベンゾアゼピンケタール誘導体、およびそれを経由する4,4−ジフルオロベンゾアゼピン−5−オン誘導体の製造方法
EP0346235A1 (fr) Nouveau procédé de préparation de dérivés N-(vinblastinoyl-23) d'acide amino-1 méthylphosphonique
FR2597869A1 (fr) Nouveaux derives d'ergolene, compositions pharmaceutiques les contenant et procede pour leur preparation
EP2109609B1 (fr) Nouveau dérive de la quinuclidine utile dans la préparation de la mequitazine
JPH0441148B2 (sv)
FR2560872A1 (fr) Procede utilisant un seul solvant pour la preparation d'esters de 3,5-dibromo-4-hydroxybenzonitrile