CS214756B2 - Method of making the 6-beta-substituted derivatives of the pennicilane acid - Google Patents

Method of making the 6-beta-substituted derivatives of the pennicilane acid Download PDF

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Publication number
CS214756B2
CS214756B2 CS803351A CS335180A CS214756B2 CS 214756 B2 CS214756 B2 CS 214756B2 CS 803351 A CS803351 A CS 803351A CS 335180 A CS335180 A CS 335180A CS 214756 B2 CS214756 B2 CS 214756B2
Authority
CS
Czechoslovakia
Prior art keywords
acid
group
singlet
ester
alpha
Prior art date
Application number
CS803351A
Other languages
Czech (cs)
English (en)
Inventor
John E G Kemp
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of CS214756B2 publication Critical patent/CS214756B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/28—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with modified 2-carboxyl group
    • C07D499/32—Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/04—Preparation
    • C07D499/10—Modification of an amino radical directly attached in position 6
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CS803351A 1979-05-19 1980-05-14 Method of making the 6-beta-substituted derivatives of the pennicilane acid CS214756B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7917505 1979-05-19

Publications (1)

Publication Number Publication Date
CS214756B2 true CS214756B2 (en) 1982-05-28

Family

ID=10505288

Family Applications (1)

Application Number Title Priority Date Filing Date
CS803351A CS214756B2 (en) 1979-05-19 1980-05-14 Method of making the 6-beta-substituted derivatives of the pennicilane acid

Country Status (28)

Country Link
US (1) US4356122A (sv)
JP (1) JPS5941994B2 (sv)
KR (1) KR840000079B1 (sv)
AR (1) AR225038A1 (sv)
AT (1) AT366694B (sv)
AU (1) AU517488B2 (sv)
BE (1) BE883319A (sv)
CA (1) CA1140916A (sv)
CH (1) CH650262A5 (sv)
CS (1) CS214756B2 (sv)
DD (1) DD151310A5 (sv)
DE (1) DE3018847C2 (sv)
DK (1) DK155180A (sv)
ES (1) ES8105737A1 (sv)
FI (1) FI71562C (sv)
FR (1) FR2457293A1 (sv)
GR (1) GR68461B (sv)
IE (1) IE49804B1 (sv)
IL (1) IL60097A (sv)
IT (1) IT1140946B (sv)
LU (1) LU82458A1 (sv)
NL (1) NL180937C (sv)
NO (1) NO801473L (sv)
PH (1) PH15033A (sv)
PL (1) PL224188A1 (sv)
PT (1) PT71253A (sv)
SE (1) SE449995B (sv)
ZA (1) ZA802908B (sv)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA803742B (en) * 1979-07-02 1981-06-24 Beecham Group Ltd Penicillanic acid derivatives, their preparation and use
JPS6034969A (ja) * 1983-08-08 1985-02-22 Toyama Chem Co Ltd 新規なペニシラン酸誘導体およびその塩類

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5749555B2 (sv) * 1973-04-04 1982-10-22
US4282149A (en) * 1977-03-21 1981-08-04 Massachusetts Institute Of Technology Carbon and oxygen analogs of penicillin
US4265882A (en) * 1977-10-03 1981-05-05 Massachusetts Institute Of Technology Sulphur analogs of penicillins having a nucleophile substituted in the 6 and 7 position, respectively

Also Published As

Publication number Publication date
NO801473L (no) 1980-11-20
SE8003676L (sv) 1980-11-20
FR2457293A1 (fr) 1980-12-19
JPS5941994B2 (ja) 1984-10-11
DE3018847C2 (de) 1982-09-30
NL180937B (nl) 1986-12-16
ES491612A0 (es) 1981-05-16
PL224188A1 (sv) 1981-02-13
KR830002769A (ko) 1983-05-30
DD151310A5 (de) 1981-10-14
PH15033A (en) 1982-05-20
NL180937C (nl) 1987-05-18
US4356122A (en) 1982-10-26
SE449995B (sv) 1987-06-01
GR68461B (sv) 1981-12-30
IE801024L (en) 1980-11-19
ATA259780A (de) 1981-09-15
ZA802908B (en) 1981-05-27
DK155180A (da) 1980-11-20
AU5846880A (en) 1980-11-27
IE49804B1 (en) 1985-12-25
FI71562B (fi) 1986-10-10
JPS55157588A (en) 1980-12-08
FI801581A (fi) 1980-11-20
PT71253A (en) 1980-06-01
IT1140946B (it) 1986-10-10
FR2457293B1 (sv) 1983-05-20
DE3018847A1 (de) 1980-12-11
ES8105737A1 (es) 1981-05-16
CH650262A5 (de) 1985-07-15
AU517488B2 (en) 1981-08-06
AT366694B (de) 1982-04-26
KR840000079B1 (ko) 1984-02-08
IL60097A0 (en) 1980-07-31
BE883319A (fr) 1980-11-14
NL8002843A (nl) 1980-11-21
CA1140916A (en) 1983-02-08
IL60097A (en) 1983-02-23
IT8022104A0 (it) 1980-05-16
FI71562C (sv) 1987-01-19
LU82458A1 (fr) 1980-10-08
AR225038A1 (es) 1982-02-15

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