CS208788B2 - Method of preparation of the new 4-/2-imidazoline-2-yl-amino-2,1,3-benzothiadiazole derivatives - Google Patents

Method of preparation of the new 4-/2-imidazoline-2-yl-amino-2,1,3-benzothiadiazole derivatives Download PDF

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Publication number
CS208788B2
CS208788B2 CS733243A CS584579A CS208788B2 CS 208788 B2 CS208788 B2 CS 208788B2 CS 733243 A CS733243 A CS 733243A CS 584579 A CS584579 A CS 584579A CS 208788 B2 CS208788 B2 CS 208788B2
Authority
CS
Czechoslovakia
Prior art keywords
formula
compounds
benzothiadiazole
chloro
reacting
Prior art date
Application number
CS733243A
Other languages
Czech (cs)
English (en)
Inventor
Peter Neumann
Original Assignee
Wander Ag Dr A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wander Ag Dr A filed Critical Wander Ag Dr A
Publication of CS208788B2 publication Critical patent/CS208788B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/14—Thiadiazoles; Hydrogenated thiadiazoles condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
CS733243A 1972-05-09 1973-05-07 Method of preparation of the new 4-/2-imidazoline-2-yl-amino-2,1,3-benzothiadiazole derivatives CS208788B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH686572A CH570401A5 (fi) 1972-05-09 1972-05-09

Publications (1)

Publication Number Publication Date
CS208788B2 true CS208788B2 (en) 1981-09-15

Family

ID=4316243

Family Applications (2)

Application Number Title Priority Date Filing Date
CS733243A CS202052B2 (en) 1972-05-09 1973-05-07 Process for preparing new 4-/2-imidazolin-2-yl-amino/-2,1,3-benzothiadiazoles
CS733243A CS208788B2 (en) 1972-05-09 1973-05-07 Method of preparation of the new 4-/2-imidazoline-2-yl-amino-2,1,3-benzothiadiazole derivatives

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CS733243A CS202052B2 (en) 1972-05-09 1973-05-07 Process for preparing new 4-/2-imidazolin-2-yl-amino/-2,1,3-benzothiadiazoles

Country Status (26)

Country Link
US (1) US3843668A (fi)
JP (3) JPS5533718B2 (fi)
AT (1) AT336006B (fi)
BE (1) BE799332A (fi)
CH (1) CH570401A5 (fi)
CS (2) CS202052B2 (fi)
CY (1) CY989A (fi)
DD (1) DD106180A5 (fi)
DE (1) DE2322880C2 (fi)
DK (1) DK135454B (fi)
ES (3) ES414470A1 (fi)
FI (1) FI60010C (fi)
FR (1) FR2183930B1 (fi)
GB (2) GB1429926A (fi)
HK (1) HK11179A (fi)
HU (1) HU166329B (fi)
IE (1) IE38012B1 (fi)
IL (2) IL49205A (fi)
MY (1) MY7900117A (fi)
NL (1) NL161445C (fi)
NO (1) NO138566C (fi)
PL (1) PL89214B1 (fi)
SE (1) SE386445B (fi)
SU (1) SU493966A3 (fi)
YU (4) YU36174B (fi)
ZA (1) ZA733143B (fi)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5930899B2 (ja) * 1973-02-01 1984-07-30 隆弘 上野 内燃機関の制動方法及びその装置
GB1559811A (en) * 1975-07-28 1980-01-30 Sandoz Ltd Pharmaceutically active benzothiadiazole derivatives
US4217356A (en) * 1975-08-22 1980-08-12 Sandoz Ltd. 2-Imidazolinylamino-2,1,3-benzothiadiazoles
CH613966A5 (en) * 1975-08-22 1979-10-31 Sandoz Ag Process for the preparation of novel 5-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazoles
CH632268A5 (de) * 1977-01-14 1982-09-30 Sandoz Ag Verfahren zur herstellung von neuen heterocyclylaminoderivaten.
FR2499991A1 (fr) * 1981-02-19 1982-08-20 Sandoz Sa Nouveaux 2,1,3-benzothiadiazoles et 2,1,3-benzoxadiazoles, leur preparation et leur application comme medicaments
FR2502951B1 (fr) * 1981-04-06 1985-12-06 Sandoz Sa Compositions pharmaceutiques topiques sous forme d'une micro-emulsion
JPS5826094U (ja) * 1981-08-13 1983-02-19 ヤマハ株式会社 電子楽器の制御装置
JPS61268828A (ja) * 1985-05-22 1986-11-28 Kubota Ltd 圧縮空気取出装置付き容積形内燃機関
JPH0622121Y2 (ja) * 1988-01-18 1994-06-08 川崎重工業株式会社 空気圧縮機兼用多気筒エンジン
JP2668816B2 (ja) * 1993-09-09 1997-10-27 株式会社パーマケム・アジア ベンゾチアジアゾール誘導体の製法
WO2003079972A2 (en) 2002-02-22 2003-10-02 New River Parmaceuticals Inc. Active agent delivery systems and methods for protecting and administering active agents
US6455557B1 (en) 2001-11-28 2002-09-24 Elan Pharmaceuticals, Inc. Method of reducing somnolence in patients treated with tizanidine
US20040220240A1 (en) * 2001-11-28 2004-11-04 Pellegrini Cara A. Method of increasing the extent of absorption of tizanidine
GB0224198D0 (en) * 2002-10-17 2002-11-27 Novartis Ag Organic compounds
CN101355876B (zh) 2005-11-09 2012-09-05 康宾纳特克斯公司 一种适用于眼部给药的组合物
WO2008008394A1 (en) * 2006-07-12 2008-01-17 Transform Pharmaceuticals, Inc. Tizanidine succinate salt forms and methods of making and using the same
US8524749B2 (en) * 2007-02-09 2013-09-03 Alza Corporation Controlled release compositions of tizanidine
CZ301889B6 (cs) 2008-12-18 2010-07-21 Farmak, A. S. Zpusob prípravy tizanidinu hydrochloridu
JP6149183B2 (ja) 2011-10-24 2017-06-21 ブレイバーン ファーマシューティカルズ，インコーポレイティド 移植可能チザニジン組成物及びその治療方法
CN106946874A (zh) * 2017-04-07 2017-07-14 四川智强医药科技开发有限公司 替扎尼定的脱色方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1211341A (fr) * 1955-12-19 1960-03-15 A Wander Dr Procédé pour la préparation de 2-amino-imidazolines
BE754832A (fr) * 1969-08-14 1971-02-15 Beecham Group Ltd Iminazolines

Also Published As

Publication number Publication date
YU50479A (en) 1981-04-30
YU36026B (en) 1981-11-13
US3843668A (en) 1974-10-22
IE38013L (en) 1973-11-09
PL89214B1 (fi) 1976-11-30
YU50679A (en) 1981-04-30
YU119673A (en) 1981-06-30
AU5540873A (en) 1974-11-14
FI60010C (fi) 1981-11-10
ES440598A1 (es) 1977-05-16
IE38012B1 (en) 1977-12-07
AT336006B (de) 1977-04-12
NL161445B (nl) 1979-09-17
ZA733143B (en) 1975-01-29
HU166329B (fi) 1975-02-28
DE2322880C2 (de) 1982-09-23
BE799332A (fr) 1973-11-09
JPS5533718B2 (fi) 1980-09-02
JPS5350168A (en) 1978-05-08
ES440599A1 (es) 1977-05-16
FR2183930B1 (fi) 1976-03-05
SU493966A3 (ru) 1975-11-28
JPS5543081A (en) 1980-03-26
MY7900117A (en) 1979-12-31
NO138566B (no) 1978-06-19
JPS4954370A (fi) 1974-05-27
FI60010B (fi) 1981-07-31
CS202052B2 (en) 1980-12-31
NL7306228A (fi) 1973-11-13
FR2183930A1 (fi) 1973-12-21
JPS562071B2 (fi) 1981-01-17
ES414470A1 (es) 1976-05-01
IL42231A (en) 1977-06-30
DD106180A5 (fi) 1974-06-05
IL42231A0 (en) 1973-07-30
IL49205A (en) 1977-05-31
GB1429926A (en) 1976-03-31
ATA403273A (de) 1976-08-15
GB1429683A (en) 1976-03-24
IL49205A0 (en) 1976-05-31
SE386445B (sv) 1976-08-09
JPS5442983B2 (fi) 1979-12-17
YU36024B (en) 1981-11-13
YU36025B (en) 1981-11-13
YU36174B (en) 1982-02-25
CH570401A5 (fi) 1975-12-15
DK135454C (fi) 1977-10-17
DE2322880A1 (de) 1973-11-22
YU50579A (en) 1981-04-30
HK11179A (en) 1979-03-16
CY989A (en) 1979-08-02
DK135454B (da) 1977-05-02
NO138566C (no) 1978-09-27
NL161445C (nl) 1980-02-15

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