CO5660259A2 - Cristal derivado de benzimidazol y procedimiento para producirlo - Google Patents
Cristal derivado de benzimidazol y procedimiento para producirloInfo
- Publication number
- CO5660259A2 CO5660259A2 CO05115024A CO05115024A CO5660259A2 CO 5660259 A2 CO5660259 A2 CO 5660259A2 CO 05115024 A CO05115024 A CO 05115024A CO 05115024 A CO05115024 A CO 05115024A CO 5660259 A2 CO5660259 A2 CO 5660259A2
- Authority
- CO
- Colombia
- Prior art keywords
- benzimidazol
- procedure
- produce
- crystal
- crystal derived
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Otolaryngology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
1.- Un cristal de ácido 4-(1-((4-metilbenzotiofen-3-il)metil)benzimidazol-2-iltio)butanoico o un solvato del mismo.Un procedimiento para producir un cristal B, que comprende llevar a cabo una cristalización por enfriamiento a partir de una solución de ácido 4-(1-((4-metilbenzotiofen-3-il)metil)benzimidazol-2-iltio)butanoico, y ácido acético, tetrahidrofurano, metanol, 2-butona, agua, o un solvente mixto de dos o más clases seleccionadas entre estos.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2003135567 | 2003-05-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
CO5660259A2 true CO5660259A2 (es) | 2006-07-31 |
Family
ID=33447189
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO05115024A CO5660259A2 (es) | 2003-05-14 | 2005-11-11 | Cristal derivado de benzimidazol y procedimiento para producirlo |
Country Status (25)
Country | Link |
---|---|
US (1) | US7649008B2 (es) |
EP (1) | EP1626048A4 (es) |
JP (1) | JPWO2004101551A1 (es) |
KR (1) | KR20060011997A (es) |
CN (1) | CN1788007A (es) |
AR (1) | AR044340A1 (es) |
AU (1) | AU2004238708A1 (es) |
BR (1) | BRPI0410266A (es) |
CA (1) | CA2523978A1 (es) |
CL (1) | CL2004001034A1 (es) |
CO (1) | CO5660259A2 (es) |
EC (1) | ECSP056162A (es) |
IS (1) | IS8177A (es) |
MA (1) | MA27805A1 (es) |
MX (1) | MXPA05011851A (es) |
NO (1) | NO20055181L (es) |
NZ (1) | NZ542978A (es) |
PE (1) | PE20050203A1 (es) |
RU (1) | RU2332417C2 (es) |
SA (1) | SA04250117B1 (es) |
TN (1) | TNSN05288A1 (es) |
TW (1) | TW200505911A (es) |
UA (1) | UA81493C2 (es) |
WO (1) | WO2004101551A1 (es) |
ZA (1) | ZA200508640B (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CL2004001034A1 (es) | 2003-05-14 | 2005-03-28 | Teijin Pharma Ltd | Formas cristalinas de acido 4-(1-((,etilbenzotiofen-3-il)me til)benzimidazol-2-iltio)butanoico; procedimiento de preparacion de las formas cristalinas; composicion farmaceutica; y su uso para el tratamiento de enfermedades inflamatorias, alergicas, r |
WO2005018672A1 (ja) * | 2003-08-22 | 2005-03-03 | Teijin Pharma Limited | キマーゼ阻害剤を有効成分として含有する薬剤 |
WO2006052026A1 (ja) * | 2004-11-12 | 2006-05-18 | Teijin Pharma Limited | ベンズイミダゾール誘導体の酸性塩及びその結晶 |
JP2016150917A (ja) * | 2015-02-17 | 2016-08-22 | 株式会社トクヤマ | バルサルタンの結晶の製造方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE72244T1 (de) | 1986-03-21 | 1992-02-15 | Heumann Pharma Gmbh & Co | Kristalline, wasserfreie sigma -form von 2-(4-(2furoyl-(2-piperazin)-1-yl>-4-amino-6,7- dimethoxychinazolinhydrochlorid und verfahren zu ihrer herstellung. |
US5015646A (en) | 1987-08-28 | 1991-05-14 | Bristol-Myers Squibb Co. | Pharmaceutically useful polymorphic modification of buspirone |
JP3668494B2 (ja) | 1994-05-31 | 2005-07-06 | 帝人株式会社 | ナフタレン誘導体 |
ES2150353B1 (es) | 1998-04-15 | 2001-07-01 | Esteve Labor Dr | Tienilazolilalcoxietanaminas, su preparacion y su aplicacion como medicamentos. |
US20040010004A1 (en) * | 2000-01-17 | 2004-01-15 | Naoki Tsuchiya | Benzimidazole derivatives |
CA2336909C (en) | 1998-07-15 | 2009-10-20 | Teijin Limited | Thiobenzimidazole derivatives which are useful as inhibitors of human chymase activity |
IL150565A0 (en) | 2000-01-17 | 2003-02-12 | Teijin Ltd | Benzimidazole derivatives and pharmaceutical compositions containing the same |
JP3999128B2 (ja) | 2001-02-22 | 2007-10-31 | 帝人株式会社 | ベンゾ[b]チオフェン誘導体、およびその製造方法 |
US6774245B2 (en) | 2001-05-07 | 2004-08-10 | Teijin Limited | 3-Hydroxymethylbenzo[b]thiophene derivatives and process for their preparation |
CA2442761A1 (en) | 2001-08-24 | 2003-03-06 | Teijin Limited | Drugs comprising chymase inhibitors and ace inhibitors as effective ingredients |
CL2004001034A1 (es) | 2003-05-14 | 2005-03-28 | Teijin Pharma Ltd | Formas cristalinas de acido 4-(1-((,etilbenzotiofen-3-il)me til)benzimidazol-2-iltio)butanoico; procedimiento de preparacion de las formas cristalinas; composicion farmaceutica; y su uso para el tratamiento de enfermedades inflamatorias, alergicas, r |
-
2004
- 2004-05-13 CL CL200401034A patent/CL2004001034A1/es unknown
- 2004-05-14 US US10/556,683 patent/US7649008B2/en not_active Expired - Fee Related
- 2004-05-14 MX MXPA05011851A patent/MXPA05011851A/es unknown
- 2004-05-14 BR BRPI0410266-5A patent/BRPI0410266A/pt not_active IP Right Cessation
- 2004-05-14 TW TW093113785A patent/TW200505911A/zh unknown
- 2004-05-14 PE PE2004000502A patent/PE20050203A1/es not_active Application Discontinuation
- 2004-05-14 NZ NZ542978A patent/NZ542978A/en unknown
- 2004-05-14 UA UAA200511908A patent/UA81493C2/xx unknown
- 2004-05-14 RU RU2005138868/04A patent/RU2332417C2/ru not_active IP Right Cessation
- 2004-05-14 WO PCT/JP2004/006887 patent/WO2004101551A1/ja active Application Filing
- 2004-05-14 AU AU2004238708A patent/AU2004238708A1/en not_active Abandoned
- 2004-05-14 JP JP2005506263A patent/JPWO2004101551A1/ja not_active Ceased
- 2004-05-14 CA CA002523978A patent/CA2523978A1/en not_active Abandoned
- 2004-05-14 EP EP04733128A patent/EP1626048A4/en not_active Withdrawn
- 2004-05-14 AR ARP040101656A patent/AR044340A1/es unknown
- 2004-05-14 CN CNA2004800127952A patent/CN1788007A/zh active Pending
- 2004-05-14 KR KR1020057021506A patent/KR20060011997A/ko not_active Application Discontinuation
- 2004-05-15 SA SA4250117A patent/SA04250117B1/ar unknown
-
2005
- 2005-10-25 ZA ZA200508640A patent/ZA200508640B/en unknown
- 2005-11-03 NO NO20055181A patent/NO20055181L/no not_active Application Discontinuation
- 2005-11-11 CO CO05115024A patent/CO5660259A2/es not_active Application Discontinuation
- 2005-11-14 EC EC2005006162A patent/ECSP056162A/es unknown
- 2005-11-14 TN TNP2005000288A patent/TNSN05288A1/en unknown
- 2005-11-14 MA MA28603A patent/MA27805A1/fr unknown
- 2005-12-13 IS IS8177A patent/IS8177A/is unknown
Also Published As
Publication number | Publication date |
---|---|
NZ542978A (en) | 2009-04-30 |
IS8177A (is) | 2005-12-13 |
EP1626048A4 (en) | 2008-11-12 |
ECSP056162A (es) | 2006-04-19 |
US20060293375A1 (en) | 2006-12-28 |
NO20055181L (no) | 2006-01-24 |
TW200505911A (en) | 2005-02-16 |
AR044340A1 (es) | 2005-09-07 |
PE20050203A1 (es) | 2005-03-26 |
NO20055181D0 (no) | 2005-11-03 |
RU2332417C2 (ru) | 2008-08-27 |
SA04250117B1 (ar) | 2009-09-02 |
JPWO2004101551A1 (ja) | 2006-07-13 |
CA2523978A1 (en) | 2004-11-25 |
MXPA05011851A (es) | 2006-02-17 |
US7649008B2 (en) | 2010-01-19 |
EP1626048A1 (en) | 2006-02-15 |
ZA200508640B (en) | 2007-02-28 |
WO2004101551A1 (ja) | 2004-11-25 |
TNSN05288A1 (en) | 2007-07-10 |
AU2004238708A1 (en) | 2004-11-25 |
KR20060011997A (ko) | 2006-02-06 |
RU2005138868A (ru) | 2006-07-10 |
CL2004001034A1 (es) | 2005-03-28 |
MA27805A1 (fr) | 2006-03-01 |
BRPI0410266A (pt) | 2006-05-16 |
CN1788007A (zh) | 2006-06-14 |
UA81493C2 (en) | 2008-01-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC | Application refused |