CO5660259A2 - Cristal derivado de benzimidazol y procedimiento para producirlo - Google Patents

Cristal derivado de benzimidazol y procedimiento para producirlo

Info

Publication number
CO5660259A2
CO5660259A2 CO05115024A CO05115024A CO5660259A2 CO 5660259 A2 CO5660259 A2 CO 5660259A2 CO 05115024 A CO05115024 A CO 05115024A CO 05115024 A CO05115024 A CO 05115024A CO 5660259 A2 CO5660259 A2 CO 5660259A2
Authority
CO
Colombia
Prior art keywords
benzimidazol
procedure
produce
crystal
crystal derived
Prior art date
Application number
CO05115024A
Other languages
English (en)
Inventor
Mitsuri Teramoto
Naoki Tsuchiya
Hiroshi Saitoh
Original Assignee
Teijin Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33447189&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO5660259(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Teijin Pharma Ltd filed Critical Teijin Pharma Ltd
Publication of CO5660259A2 publication Critical patent/CO5660259A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Otolaryngology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

1.- Un cristal de ácido 4-(1-((4-metilbenzotiofen-3-il)metil)benzimidazol-2-iltio)butanoico o un solvato del mismo.Un procedimiento para producir un cristal B, que comprende llevar a cabo una cristalización por enfriamiento a partir de una solución de ácido 4-(1-((4-metilbenzotiofen-3-il)metil)benzimidazol-2-iltio)butanoico, y ácido acético, tetrahidrofurano, metanol, 2-butona, agua, o un solvente mixto de dos o más clases seleccionadas entre estos.
CO05115024A 2003-05-14 2005-11-11 Cristal derivado de benzimidazol y procedimiento para producirlo CO5660259A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2003135567 2003-05-14

Publications (1)

Publication Number Publication Date
CO5660259A2 true CO5660259A2 (es) 2006-07-31

Family

ID=33447189

Family Applications (1)

Application Number Title Priority Date Filing Date
CO05115024A CO5660259A2 (es) 2003-05-14 2005-11-11 Cristal derivado de benzimidazol y procedimiento para producirlo

Country Status (25)

Country Link
US (1) US7649008B2 (es)
EP (1) EP1626048A4 (es)
JP (1) JPWO2004101551A1 (es)
KR (1) KR20060011997A (es)
CN (1) CN1788007A (es)
AR (1) AR044340A1 (es)
AU (1) AU2004238708A1 (es)
BR (1) BRPI0410266A (es)
CA (1) CA2523978A1 (es)
CL (1) CL2004001034A1 (es)
CO (1) CO5660259A2 (es)
EC (1) ECSP056162A (es)
IS (1) IS8177A (es)
MA (1) MA27805A1 (es)
MX (1) MXPA05011851A (es)
NO (1) NO20055181L (es)
NZ (1) NZ542978A (es)
PE (1) PE20050203A1 (es)
RU (1) RU2332417C2 (es)
SA (1) SA04250117B1 (es)
TN (1) TNSN05288A1 (es)
TW (1) TW200505911A (es)
UA (1) UA81493C2 (es)
WO (1) WO2004101551A1 (es)
ZA (1) ZA200508640B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CL2004001034A1 (es) 2003-05-14 2005-03-28 Teijin Pharma Ltd Formas cristalinas de acido 4-(1-((,etilbenzotiofen-3-il)me til)benzimidazol-2-iltio)butanoico; procedimiento de preparacion de las formas cristalinas; composicion farmaceutica; y su uso para el tratamiento de enfermedades inflamatorias, alergicas, r
JP4387360B2 (ja) * 2003-08-22 2009-12-16 帝人ファーマ株式会社 キマーゼ阻害剤を有効成分として含有する薬剤
JPWO2006052026A1 (ja) * 2004-11-12 2008-05-29 帝人ファーマ株式会社 ベンズイミダゾール誘導体の酸性塩及びその結晶
JP2016150917A (ja) * 2015-02-17 2016-08-22 株式会社トクヤマ バルサルタンの結晶の製造方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0237608B1 (de) 1986-03-21 1992-01-29 HEUMANN PHARMA GMBH & CO Kristalline, wasserfreie Sigma -Form von 2-[4-(2-Furoyl-(2-piperazin)-1-yl]-4-amino-6,7-dimethoxychinazolinhydrochlorid und Verfahren zu ihrer Herstellung
US5015646A (en) 1987-08-28 1991-05-14 Bristol-Myers Squibb Co. Pharmaceutically useful polymorphic modification of buspirone
ES2138206T3 (es) 1994-05-31 2000-01-01 Teijin Ltd Derivados de naftaleno.
ES2150353B1 (es) 1998-04-15 2001-07-01 Esteve Labor Dr Tienilazolilalcoxietanaminas, su preparacion y su aplicacion como medicamentos.
KR100903531B1 (ko) 1998-07-15 2009-06-23 데이진 가부시키가이샤 티오벤즈이미다졸 유도체
US20040010004A1 (en) * 2000-01-17 2004-01-15 Naoki Tsuchiya Benzimidazole derivatives
CN1198819C (zh) * 2000-01-17 2005-04-27 帝人株式会社 苯并咪唑衍生物
NZ522150A (en) 2001-02-22 2006-03-31 Teijin Ltd Benzo[b]thiophene derivatives and processes for preparing the same
ATE404551T1 (de) 2001-05-07 2008-08-15 Teijin Pharma Ltd 3-hydroxymethylbenzo b thiophen-derivate und verfahren zu deren herstellung
KR100902799B1 (ko) * 2001-08-24 2009-06-12 데이진 가부시키가이샤 키마제 저해제 및 ａｃｅ 저해제를 유효성분으로 함유하는약제
CL2004001034A1 (es) 2003-05-14 2005-03-28 Teijin Pharma Ltd Formas cristalinas de acido 4-(1-((,etilbenzotiofen-3-il)me til)benzimidazol-2-iltio)butanoico; procedimiento de preparacion de las formas cristalinas; composicion farmaceutica; y su uso para el tratamiento de enfermedades inflamatorias, alergicas, r

Also Published As

Publication number Publication date
KR20060011997A (ko) 2006-02-06
US20060293375A1 (en) 2006-12-28
AU2004238708A1 (en) 2004-11-25
TNSN05288A1 (en) 2007-07-10
ECSP056162A (es) 2006-04-19
MXPA05011851A (es) 2006-02-17
EP1626048A1 (en) 2006-02-15
EP1626048A4 (en) 2008-11-12
NO20055181D0 (no) 2005-11-03
CA2523978A1 (en) 2004-11-25
BRPI0410266A (pt) 2006-05-16
RU2005138868A (ru) 2006-07-10
WO2004101551A1 (ja) 2004-11-25
TW200505911A (en) 2005-02-16
MA27805A1 (fr) 2006-03-01
NO20055181L (no) 2006-01-24
UA81493C2 (en) 2008-01-10
RU2332417C2 (ru) 2008-08-27
CL2004001034A1 (es) 2005-03-28
SA04250117B1 (ar) 2009-09-02
AR044340A1 (es) 2005-09-07
NZ542978A (en) 2009-04-30
PE20050203A1 (es) 2005-03-26
IS8177A (is) 2005-12-13
ZA200508640B (en) 2007-02-28
JPWO2004101551A1 (ja) 2006-07-13
US7649008B2 (en) 2010-01-19
CN1788007A (zh) 2006-06-14

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