CN1713914A - 用于治疗慢性阻塞性肺病的新药物 - Google Patents

用于治疗慢性阻塞性肺病的新药物 Download PDF

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Publication number
CN1713914A
CN1713914A CNA2003801030945A CN200380103094A CN1713914A CN 1713914 A CN1713914 A CN 1713914A CN A2003801030945 A CNA2003801030945 A CN A2003801030945A CN 200380103094 A CN200380103094 A CN 200380103094A CN 1713914 A CN1713914 A CN 1713914A
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China
Prior art keywords
methyl
alkyl
ethyl
chemical compound
general formula
Prior art date
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Pending
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CNA2003801030945A
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English (en)
Chinese (zh)
Inventor
蒂里·布索
弗兰克·比特纳
英戈·科恩茨基
萨拜因·佩斯特尔
安德烈亚斯·施纳普
赫尔曼·斯科伦伯格
库尔特·施罗姆
克劳迪娅·海因
克劳斯·鲁道夫
菲利普·勒斯滕伯格
克里斯托弗·霍恩克
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Boehringer Ingelheim Pharma GmbH and Co KG
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32185709&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN1713914(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Pharma GmbH and Co KG filed Critical Boehringer Ingelheim Pharma GmbH and Co KG
Publication of CN1713914A publication Critical patent/CN1713914A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CNA2003801030945A 2002-11-15 2003-11-11 用于治疗慢性阻塞性肺病的新药物 Pending CN1713914A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10253282A DE10253282A1 (de) 2002-11-15 2002-11-15 Neue Arzneimittel zur Behandlung von chronisch obstruktiver Lungenerkrankung
DE10253282.6 2002-11-15

Related Child Applications (2)

Application Number Title Priority Date Filing Date
CN200910266327A Division CN101735166A (zh) 2002-11-15 2003-11-11 用于治疗慢性阻塞性肺病的新药物
CN201010004697A Division CN101817800A (zh) 2002-11-15 2003-11-11 用于治疗慢性阻塞性肺病的新药物

Publications (1)

Publication Number Publication Date
CN1713914A true CN1713914A (zh) 2005-12-28

Family

ID=32185709

Family Applications (3)

Application Number Title Priority Date Filing Date
CN200910266327A Pending CN101735166A (zh) 2002-11-15 2003-11-11 用于治疗慢性阻塞性肺病的新药物
CNA2003801030945A Pending CN1713914A (zh) 2002-11-15 2003-11-11 用于治疗慢性阻塞性肺病的新药物
CN201010004697A Pending CN101817800A (zh) 2002-11-15 2003-11-11 用于治疗慢性阻塞性肺病的新药物

Family Applications Before (1)

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CN200910266327A Pending CN101735166A (zh) 2002-11-15 2003-11-11 用于治疗慢性阻塞性肺病的新药物

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CN201010004697A Pending CN101817800A (zh) 2002-11-15 2003-11-11 用于治疗慢性阻塞性肺病的新药物

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CN101578274B (zh) * 2007-01-25 2012-08-29 贝林格尔.英格海姆国际有限公司 制备β-模拟物的方法

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