CN1694889A - 用于调节lgE和抑制细胞增殖的苯基－氮杂－苯并咪唑化合物 - Google Patents

用于调节lgE和抑制细胞增殖的苯基－氮杂－苯并咪唑化合物 Download PDF

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Publication number
CN1694889A
CN1694889A CNA038250934A CN03825093A CN1694889A CN 1694889 A CN1694889 A CN 1694889A CN A038250934 A CNA038250934 A CN A038250934A CN 03825093 A CN03825093 A CN 03825093A CN 1694889 A CN1694889 A CN 1694889A
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China
Prior art keywords
substituted
group
alkyl
heteroaryl
phenyl
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Pending
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CNA038250934A
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English (en)
Chinese (zh)
Inventor
伽各蒂施·C·索卡
理查德·J·托马斯
马克·L·理查德斯
安加纳·辛哈
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Avanir Pharmaceuticals Inc
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Avanir Pharmaceuticals Inc
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Publication of CN1694889A publication Critical patent/CN1694889A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D515/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D515/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D515/04—Ortho-condensed systems

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CNA038250934A 2002-09-12 2003-09-12 用于调节lgE和抑制细胞增殖的苯基－氮杂－苯并咪唑化合物 Pending CN1694889A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41076102P 2002-09-12 2002-09-12
US60/410,761 2002-09-12

Publications (1)

Publication Number Publication Date
CN1694889A true CN1694889A (zh) 2005-11-09

Family

ID=31994198

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA038250934A Pending CN1694889A (zh) 2002-09-12 2003-09-12 用于调节lgE和抑制细胞增殖的苯基－氮杂－苯并咪唑化合物

Country Status (17)

Country Link
US (1) US7256287B2 (https=)
EP (1) EP1546157A4 (https=)
JP (1) JP2006503048A (https=)
KR (1) KR20050050102A (https=)
CN (1) CN1694889A (https=)
AR (1) AR041252A1 (https=)
AU (1) AU2003279729A1 (https=)
BR (1) BR0314235A (https=)
CA (1) CA2498495A1 (https=)
MX (1) MXJL05000010A (https=)
NZ (1) NZ538547A (https=)
PE (1) PE20050036A1 (https=)
PL (1) PL375811A1 (https=)
RU (1) RU2005109911A (https=)
TW (1) TWI276631B (https=)
WO (1) WO2004024897A2 (https=)
ZA (1) ZA200502738B (https=)

Cited By (1)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103819398A (zh) * 2014-01-24 2014-05-28 河北科技大学 4-氨基-2-氯-3-硝基吡啶的合成方法
CN103819398B (zh) * 2014-01-24 2016-05-04 河北科技大学 4-氨基-2-氯-3-硝基吡啶的合成方法

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JP2006503048A (ja) 2006-01-26
MXJL05000010A (es) 2005-06-07
US20040116466A1 (en) 2004-06-17
BR0314235A (pt) 2005-08-09
WO2004024897A3 (en) 2004-08-26
KR20050050102A (ko) 2005-05-27
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AR041252A1 (es) 2005-05-11
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RU2005109911A (ru) 2006-04-27
EP1546157A2 (en) 2005-06-29
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AU2003279729A1 (en) 2004-04-30
US7256287B2 (en) 2007-08-14
CA2498495A1 (en) 2004-03-25
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