CN1646161A - 自身免疫疾病的药剂和治疗方法 - Google Patents
自身免疫疾病的药剂和治疗方法 Download PDFInfo
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- CN1646161A CN1646161A CNA038089734A CN03808973A CN1646161A CN 1646161 A CN1646161 A CN 1646161A CN A038089734 A CNA038089734 A CN A038089734A CN 03808973 A CN03808973 A CN 03808973A CN 1646161 A CN1646161 A CN 1646161A
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Physical Education & Sports Medicine (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Endocrinology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Mycology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Rheumatology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35941902P | 2002-02-21 | 2002-02-21 | |
| US60/359,419 | 2002-02-21 | ||
| US42047202P | 2002-10-21 | 2002-10-21 | |
| US60/420,472 | 2002-10-21 | ||
| PCT/US2003/005549 WO2003072736A2 (en) | 2002-02-21 | 2003-02-21 | Reagents and treatment methods for autoimmune diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1646161A true CN1646161A (zh) | 2005-07-27 |
Family
ID=27767572
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA038089734A Pending CN1646161A (zh) | 2002-02-21 | 2003-02-21 | 自身免疫疾病的药剂和治疗方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US20030202975A1 (cg-RX-API-DMAC7.html) |
| EP (2) | EP1485130A4 (cg-RX-API-DMAC7.html) |
| JP (3) | JP2005526044A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20040094705A (cg-RX-API-DMAC7.html) |
| CN (1) | CN1646161A (cg-RX-API-DMAC7.html) |
| AT (1) | ATE482719T1 (cg-RX-API-DMAC7.html) |
| AU (2) | AU2003224624B2 (cg-RX-API-DMAC7.html) |
| CA (2) | CA2476776A1 (cg-RX-API-DMAC7.html) |
| DE (1) | DE60334364D1 (cg-RX-API-DMAC7.html) |
| WO (2) | WO2003072736A2 (cg-RX-API-DMAC7.html) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI447124B (zh) * | 2006-12-01 | 2014-08-01 | Medarex Llc | 結合cd22的人類抗體與其應用 |
| CN104428007A (zh) * | 2012-07-09 | 2015-03-18 | 基因泰克公司 | 包含抗cd22抗体的免疫缀合物 |
| CN104540524A (zh) * | 2012-07-09 | 2015-04-22 | 基因泰克公司 | 包含抗cd22抗体的免疫缀合物 |
| CN104582717A (zh) * | 2012-07-19 | 2015-04-29 | 雷德伍德生物科技股份有限公司 | 对cd22有特异性的抗体及其使用方法 |
Families Citing this family (202)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI239847B (en) | 1997-12-02 | 2005-09-21 | Elan Pharm Inc | N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease |
| US20080050367A1 (en) | 1998-04-07 | 2008-02-28 | Guriq Basi | Humanized antibodies that recognize beta amyloid peptide |
| US7588766B1 (en) | 2000-05-26 | 2009-09-15 | Elan Pharma International Limited | Treatment of amyloidogenic disease |
| US6761888B1 (en) | 2000-05-26 | 2004-07-13 | Neuralab Limited | Passive immunization treatment of Alzheimer's disease |
| US7790856B2 (en) | 1998-04-07 | 2010-09-07 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize beta amyloid peptide |
| US7964192B1 (en) | 1997-12-02 | 2011-06-21 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidgenic disease |
| US7696325B2 (en) * | 1999-03-10 | 2010-04-13 | Chugai Seiyaku Kabushiki Kaisha | Polypeptide inducing apoptosis |
| EP2351838A1 (en) * | 2000-10-20 | 2011-08-03 | Chugai Seiyaku Kabushiki Kaisha | Crosslinking agonistic antibodies |
| ES2304235T3 (es) * | 2000-10-20 | 2008-10-01 | Chugai Seiyaku Kabushiki Kaisha | Anticuerpo agonista de tpo modificado. |
| US7700751B2 (en) | 2000-12-06 | 2010-04-20 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize β-amyloid peptide |
| TWI255272B (en) | 2000-12-06 | 2006-05-21 | Guriq Basi | Humanized antibodies that recognize beta amyloid peptide |
| US20110045005A1 (en) | 2001-10-19 | 2011-02-24 | Craig Crowley | Compositions and methods for the treatment of tumor of hematopoietic origin |
| DE60334364D1 (de) * | 2002-02-21 | 2010-11-11 | Univ California | Behandlungsverfahren unter verwendung von anti-cd22-antikörpern |
| MY139983A (en) | 2002-03-12 | 2009-11-30 | Janssen Alzheimer Immunotherap | Humanized antibodies that recognize beta amyloid peptide |
| ATE414105T1 (de) * | 2002-10-11 | 2008-11-15 | Chugai Pharmaceutical Co Ltd | Zelltod-induzierender wirkstoff |
| JP2004279086A (ja) * | 2003-03-13 | 2004-10-07 | Konica Minolta Holdings Inc | 放射線画像変換パネル及び放射線画像変換パネルの製造方法 |
| WO2004087763A1 (ja) * | 2003-03-31 | 2004-10-14 | Chugai Seiyaku Kabushiki Kaisha | Cd22に対する改変抗体およびその利用 |
| EP1626993B1 (en) | 2003-05-09 | 2015-03-11 | Duke University | Cd20-specific antibodies and methods of employing same |
| TWI374893B (en) | 2003-05-30 | 2012-10-21 | Janssen Alzheimer Immunotherap | Humanized antibodies that recognize beta amyloid peptide |
| KR101438983B1 (ko) | 2003-11-06 | 2014-09-05 | 시애틀 지네틱스, 인크. | 리간드에 접합될 수 있는 모노메틸발린 화합물 |
| NZ547558A (en) * | 2003-11-17 | 2009-06-26 | Genentech Inc | Compositions and methods for the treatment of tumor of hematopoietic origin |
| AU2011203347B2 (en) * | 2003-11-17 | 2013-09-05 | Genentech, Inc. | Compositions and methods for the treatment of tumor of hematopoietic origin |
| US20070281327A1 (en) * | 2003-12-12 | 2007-12-06 | Kiyotaka Nakano | Methods of Screening for Modified Antibodies With Agonistic Activities |
| AU2004297109A1 (en) * | 2003-12-12 | 2005-06-23 | Chugai Seiyaku Kabushiki Kaisha | Cell death inducing agent |
| TW200530266A (en) * | 2003-12-12 | 2005-09-16 | Chugai Pharmaceutical Co Ltd | Method of reinforcing antibody activity |
| TW200530269A (en) | 2003-12-12 | 2005-09-16 | Chugai Pharmaceutical Co Ltd | Anti-Mpl antibodies |
| RU2404810C9 (ru) * | 2004-06-01 | 2015-06-20 | Дженентек, Инк. | Конъюгаты антитело-лекарственное средство и способы |
| US7889163B2 (en) * | 2004-08-27 | 2011-02-15 | Qualcomm Mems Technologies, Inc. | Drive method for MEMS devices |
| US20100111856A1 (en) | 2004-09-23 | 2010-05-06 | Herman Gill | Zirconium-radiolabeled, cysteine engineered antibody conjugates |
| CN104447992A (zh) | 2004-09-23 | 2015-03-25 | 健泰科生物技术公司 | 半胱氨酸改造的抗体和偶联物 |
| GT200500283A (es) * | 2004-10-08 | 2006-05-08 | Inmunoterapia de desordenes autoinmunes | |
| GB0425569D0 (en) * | 2004-11-19 | 2004-12-22 | Celltech R&D Ltd | Biological products |
| CA2590337C (en) | 2004-12-15 | 2017-07-11 | Neuralab Limited | Humanized amyloid beta antibodies for use in improving cognition |
| TW200636066A (en) * | 2004-12-15 | 2006-10-16 | Elan Pharm Inc | Humanized antibodies that recognize beta amyloid peptide |
| DK1853718T3 (en) | 2005-02-15 | 2015-11-09 | Univ Duke | ANTI-CD19 ANTIBODIES AND THEIR USE IN ONCOLOGY |
| EA200701766A1 (ru) | 2005-03-18 | 2008-04-28 | Домантис Лимитед | Антитела против антигенов candida |
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- 2003-02-21 AU AU2003224624A patent/AU2003224624B2/en not_active Ceased
- 2003-02-21 WO PCT/US2003/005549 patent/WO2003072736A2/en not_active Ceased
- 2003-02-21 JP JP2003570783A patent/JP2005526044A/ja active Pending
- 2003-02-21 US US10/372,481 patent/US20030202975A1/en not_active Abandoned
- 2003-02-21 AU AU2003215365A patent/AU2003215365A1/en not_active Abandoned
- 2003-02-21 EP EP03721301A patent/EP1485130A4/en not_active Withdrawn
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- 2003-02-21 US US10/371,797 patent/US20040001828A1/en not_active Abandoned
- 2003-02-21 CA CA002476776A patent/CA2476776A1/en not_active Abandoned
- 2003-02-21 AT AT03711190T patent/ATE482719T1/de not_active IP Right Cessation
- 2003-02-21 KR KR10-2004-7012900A patent/KR20040094705A/ko not_active Withdrawn
- 2003-02-21 CN CNA038089734A patent/CN1646161A/zh active Pending
- 2003-02-21 CA CA002475509A patent/CA2475509A1/en not_active Abandoned
- 2003-02-21 EP EP03711190A patent/EP1476120B1/en not_active Expired - Lifetime
- 2003-02-21 JP JP2003571424A patent/JP2005526501A/ja not_active Withdrawn
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- 2007-08-06 US US11/890,743 patent/US20080118505A1/en not_active Abandoned
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2009
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI447124B (zh) * | 2006-12-01 | 2014-08-01 | Medarex Llc | 結合cd22的人類抗體與其應用 |
| CN104428007A (zh) * | 2012-07-09 | 2015-03-18 | 基因泰克公司 | 包含抗cd22抗体的免疫缀合物 |
| CN104540524A (zh) * | 2012-07-09 | 2015-04-22 | 基因泰克公司 | 包含抗cd22抗体的免疫缀合物 |
| CN104428007B (zh) * | 2012-07-09 | 2018-03-16 | 基因泰克公司 | 包含抗cd22抗体的免疫缀合物 |
| CN104582717A (zh) * | 2012-07-19 | 2015-04-29 | 雷德伍德生物科技股份有限公司 | 对cd22有特异性的抗体及其使用方法 |
| CN104582717B (zh) * | 2012-07-19 | 2018-03-13 | 雷德伍德生物科技股份有限公司 | 对cd22有特异性的抗体及其使用方法 |
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| WO2003072036A2 (en) | 2003-09-04 |
| CA2476776A1 (en) | 2003-09-04 |
| EP1485130A2 (en) | 2004-12-15 |
| EP1476120B1 (en) | 2010-09-29 |
| ATE482719T1 (de) | 2010-10-15 |
| JP2009221224A (ja) | 2009-10-01 |
| CA2475509A1 (en) | 2003-09-04 |
| EP1485130A4 (en) | 2006-11-22 |
| US20080118505A1 (en) | 2008-05-22 |
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| US20030202975A1 (en) | 2003-10-30 |
| EP1476120A4 (en) | 2005-12-28 |
| KR20040094705A (ko) | 2004-11-10 |
| AU2003215365A1 (en) | 2003-09-09 |
| WO2003072036A3 (en) | 2003-12-31 |
| US20040001828A1 (en) | 2004-01-01 |
| WO2003072736A2 (en) | 2003-09-04 |
| JP2005526044A (ja) | 2005-09-02 |
| US20070264260A1 (en) | 2007-11-15 |
| AU2003224624A1 (en) | 2003-09-09 |
| US8734792B2 (en) | 2014-05-27 |
| AU2003224624B2 (en) | 2008-08-28 |
| EP1476120A2 (en) | 2004-11-17 |
| US20120301472A1 (en) | 2012-11-29 |
| DE60334364D1 (de) | 2010-11-11 |
| JP2005526501A (ja) | 2005-09-08 |
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