CN1509274A - 金属蛋白酶抑制剂 - Google Patents

金属蛋白酶抑制剂 Download PDF

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Publication number
CN1509274A
CN1509274A CNA028099273A CN02809927A CN1509274A CN 1509274 A CN1509274 A CN 1509274A CN A028099273 A CNA028099273 A CN A028099273A CN 02809927 A CN02809927 A CN 02809927A CN 1509274 A CN1509274 A CN 1509274A
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China
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alkyl
heteroalkyl
methyl
heteroaryl
cycloalkyl
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Pending
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CNA028099273A
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Chinese (zh)
Inventor
��١���Ƥ˹��
马蒂·莱皮斯托
˹��â�˰�����ɭФ����
马格努斯·芒克阿弗罗森肖尔德
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AstraZeneca AB
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AstraZeneca AB
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Publication of CN1509274A publication Critical patent/CN1509274A/zh
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    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
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    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
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    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • Reproductive Health (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
CNA028099273A 2001-03-15 2002-03-13 金属蛋白酶抑制剂 Pending CN1509274A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0100903A SE0100903D0 (sv) 2001-03-15 2001-03-15 Compounds
SE01009034 2001-03-15

Publications (1)

Publication Number Publication Date
CN1509274A true CN1509274A (zh) 2004-06-30

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Family Applications (2)

Application Number Title Priority Date Filing Date
CNA028099273A Pending CN1509274A (zh) 2001-03-15 2002-03-13 金属蛋白酶抑制剂
CNB028097890A Expired - Fee Related CN1313448C (zh) 2001-03-15 2002-03-13 金属蛋白酶抑制剂

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US (2) US20040116486A1 (https=)
EP (2) EP1370535A1 (https=)
JP (2) JP2004527512A (https=)
KR (2) KR20030082988A (https=)
CN (2) CN1509274A (https=)
AR (1) AR035444A1 (https=)
AU (1) AU2002237633B2 (https=)
BR (2) BR0207985A (https=)
CA (2) CA2440475A1 (https=)
CZ (2) CZ20032501A3 (https=)
EE (2) EE200300450A (https=)
HU (2) HUP0400328A3 (https=)
IL (2) IL157650A0 (https=)
IS (2) IS6945A (https=)
MX (2) MXPA03008187A (https=)
MY (1) MY129188A (https=)
NO (2) NO326088B1 (https=)
NZ (2) NZ528108A (https=)
PL (2) PL365107A1 (https=)
RU (2) RU2293730C2 (https=)
SE (1) SE0100903D0 (https=)
SK (2) SK10912003A3 (https=)
UA (2) UA77169C2 (https=)
WO (2) WO2002074752A1 (https=)
ZA (2) ZA200306738B (https=)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CO5300399A1 (es) 2000-02-25 2003-07-31 Astrazeneca Ab Heterocicliocs que contienen nitrogeno, proceso para su preparacion y composiciones farmaceuticas que los contienen
US7005439B2 (en) * 2000-06-20 2006-02-28 Astrazeneca Ab Compounds
SE0100902D0 (sv) * 2001-03-15 2001-03-15 Astrazeneca Ab Compounds
SE0100903D0 (sv) * 2001-03-15 2001-03-15 Astrazeneca Ab Compounds
US6890915B2 (en) 2001-05-25 2005-05-10 Bristol-Myers Squibb Pharma Company Hydantoins and related heterocycles as inhibitors of matrix metalloproteinases and/or TNF-α converting enzyme (TACE)
SE0103710D0 (sv) 2001-11-07 2001-11-07 Astrazeneca Ab Compounds
MY131170A (en) * 2002-03-28 2007-07-31 Nissan Chemical Ind Ltd Therapeutic agent for glomerular disease
SE0202539D0 (sv) 2002-08-27 2002-08-27 Astrazeneca Ab Compounds
SE0202692D0 (sv) * 2002-09-11 2002-09-11 Astrazeneca Ab Compounds
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