CN1290502C - 治疗普通感冒的组合物 - Google Patents

治疗普通感冒的组合物 Download PDF

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Publication number
CN1290502C
CN1290502C CNB028182871A CN02818287A CN1290502C CN 1290502 C CN1290502 C CN 1290502C CN B028182871 A CNB028182871 A CN B028182871A CN 02818287 A CN02818287 A CN 02818287A CN 1290502 C CN1290502 C CN 1290502C
Authority
CN
China
Prior art keywords
salt
xylometazoline
acid
compositions
atem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CNB028182871A
Other languages
English (en)
Chinese (zh)
Other versions
CN1555263A (zh
Inventor
汉尼·安内特·莫斯卡德
卡琳·洛温斯坦·可瑞思丁森
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Nycomed Danmark AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Danmark AS filed Critical Nycomed Danmark AS
Publication of CN1555263A publication Critical patent/CN1555263A/zh
Application granted granted Critical
Publication of CN1290502C publication Critical patent/CN1290502C/zh
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/468-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Cosmetics (AREA)
CNB028182871A 2001-09-18 2002-09-18 治疗普通感冒的组合物 Expired - Lifetime CN1290502C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200101356 2001-09-18
DKPA200101356 2001-09-18

Publications (2)

Publication Number Publication Date
CN1555263A CN1555263A (zh) 2004-12-15
CN1290502C true CN1290502C (zh) 2006-12-20

Family

ID=8160714

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB028182871A Expired - Lifetime CN1290502C (zh) 2001-09-18 2002-09-18 治疗普通感冒的组合物

Country Status (20)

Country Link
US (2) US7652030B2 (https=)
EP (2) EP1446119B1 (https=)
JP (1) JP4500045B2 (https=)
KR (1) KR100810872B1 (https=)
CN (1) CN1290502C (https=)
AT (1) ATE318601T1 (https=)
BR (1) BRPI0212586B8 (https=)
CA (1) CA2460140C (https=)
DE (1) DE60209511T2 (https=)
DK (1) DK1446119T3 (https=)
EA (1) EA008165B1 (https=)
ES (1) ES2259098T3 (https=)
HU (1) HU226527B1 (https=)
MX (1) MXPA04002500A (https=)
NO (1) NO334441B1 (https=)
NZ (1) NZ531792A (https=)
PL (1) PL208686B1 (https=)
PT (1) PT1446119E (https=)
SI (1) SI1446119T1 (https=)
WO (1) WO2003024433A2 (https=)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030055026A1 (en) 2001-04-17 2003-03-20 Dey L.P. Formoterol/steroid bronchodilating compositions and methods of use thereof
HU226527B1 (hu) * 2001-09-18 2009-03-30 Nycomed Danmark Aps Készítmények nátha kezelésére
TWI359675B (en) 2003-07-10 2012-03-11 Dey L P Bronchodilating β-agonist compositions
RU2006132043A (ru) * 2004-02-06 2008-03-20 МЕДА Фарма ГмбХ унд Ко.КГ (DE) Комбинация и фармацевтический препарат для лечения ринита
WO2005084330A2 (en) * 2004-03-02 2005-09-15 Synergia Pharma, Inc. Compositions and methods for treating nasal congestion
DE102004049008A1 (de) 2004-10-05 2006-04-06 Merck Patent Gmbh Neue Verwendung für α-Sympathomimetika mit 2-Imidazolinstruktur
JP2008525313A (ja) * 2004-12-27 2008-07-17 エーザイ・アール・アンド・ディー・マネジメント株式会社 抗痴呆薬の安定化方法
DE102006023770A1 (de) * 2006-05-20 2007-11-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Treibgasfreie Aerosolformulierung für die Inhalation
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
US20090270472A1 (en) * 2008-04-25 2009-10-29 Kenneth Gould Method to use oxymetazoline to interrupt the development of the common cold syndrome
US10011906B2 (en) 2009-03-31 2018-07-03 Beohringer Ingelheim International Gmbh Method for coating a surface of a component
WO2010133294A2 (de) 2009-05-18 2010-11-25 Boehringer Ingelheim International Gmbh Adapter, inhalationseinrichtung und zerstäuber
JP5658268B2 (ja) 2009-11-25 2015-01-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
EA026241B1 (ru) 2009-11-25 2017-03-31 Бёрингер Ингельхайм Интернациональ Гмбх Распылитель
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
WO2011160932A1 (en) 2010-06-24 2011-12-29 Boehringer Ingelheim International Gmbh Nebulizer
WO2012130757A1 (de) 2011-04-01 2012-10-04 Boehringer Ingelheim International Gmbh Medizinisches gerät mit behälter
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
WO2014158118A1 (en) * 2013-03-29 2014-10-02 Santa Farma İlaç Sanayi̇ A.Ş. Suspension composition containing ipratropium and oxymetazoline
WO2014158119A1 (en) * 2013-03-29 2014-10-02 Santa Farma İlaç Sanayi̇ A.Ş Aqueous solution composition containing ipratropium and oxymetazoline
PL2835146T3 (pl) 2013-08-09 2021-04-06 Boehringer Ingelheim International Gmbh Nebulizator
EP3030298B1 (en) 2013-08-09 2017-10-11 Boehringer Ingelheim International GmbH Nebulizer
WO2015054359A1 (en) * 2013-10-08 2015-04-16 Ebadi Mark A Methods and compositions for symptomatic reflief of the common cold
HUE055604T2 (hu) 2014-05-07 2021-12-28 Boehringer Ingelheim Int Porlasztó
AU2015257878B2 (en) 2014-05-07 2019-08-08 Boehringer Ingelheim International Gmbh Container, nebulizer and use
EA035261B1 (ru) 2014-05-07 2020-05-21 Бёрингер Ингельхайм Интернациональ Гмбх Небулайзер и контейнер
PL3236933T3 (pl) * 2014-12-24 2019-05-31 Jadran Galenski Laboratorij D D Kompozycja do podawania donosowego zawierająca wodę morską jako zaróbkę poprawiającą trwałość
MX383771B (es) * 2015-12-02 2025-03-14 Pablo Cortes Borrego Combinación de oximetazolina e ipratropio en aplicación tópica nasal para el tratamiento de la tos.
US20220031739A1 (en) * 2020-07-31 2022-02-03 Eye Therapies Llc Anti-viral compositions and methods of use thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2122719A1 (en) * 1991-11-19 1993-05-27 Jack M. Gwaltney, Jr. Combined virustatic antimediator (covam) treatment of common colds
IL101056A (en) 1992-02-24 1997-03-18 Res & Dev Co Ltd Composition for nasal treatment
GB9218834D0 (en) 1992-09-05 1992-10-21 Procter & Gamble Nasal spray products
SK280911B6 (sk) * 1992-12-09 2000-09-12 Boehringer Ingelheim Pharmaceuticals, Inc. Farmaceutický prostriedok
EP0780127A1 (en) 1995-12-19 1997-06-25 The Procter & Gamble Company A nasal spray containing a steroid and a antihistamine
DE19653969A1 (de) 1996-12-20 1998-06-25 Boehringer Ingelheim Kg Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole
JP2001524108A (ja) 1997-04-30 2001-11-27 ワーナー−ランバート・カンパニー 局所経鼻抗炎症組成物
DK1051155T3 (da) * 1998-01-30 2002-09-16 Novartis Consumer Health Sa Nasale opløsninger
CN1161104C (zh) 1998-06-18 2004-08-11 贝林格尔·英格海姆药物公司 有二种或多种活性物质的气溶胶药物制剂
TR200103694T2 (tr) 1999-06-22 2002-04-22 Boehringer Ingelheim International Gmbh Sabit ksilometazolin ve oksimetazolin çözeltisi
HU226527B1 (hu) * 2001-09-18 2009-03-30 Nycomed Danmark Aps Készítmények nátha kezelésére

Also Published As

Publication number Publication date
EP1661570A3 (en) 2012-10-24
EP1446119B1 (en) 2006-03-01
JP2005505569A (ja) 2005-02-24
WO2003024433A2 (en) 2003-03-27
EP1446119A2 (en) 2004-08-18
MXPA04002500A (es) 2004-11-22
KR20040049849A (ko) 2004-06-12
US20100093783A1 (en) 2010-04-15
JP4500045B2 (ja) 2010-07-14
HK1067984A1 (en) 2005-04-22
BR0212586B1 (pt) 2013-11-19
EP1661570A2 (en) 2006-05-31
DE60209511T2 (de) 2006-10-05
BRPI0212586B8 (pt) 2021-05-25
SI1446119T1 (sl) 2006-08-31
KR100810872B1 (ko) 2008-03-06
PL370536A1 (en) 2005-05-30
NZ531792A (en) 2006-02-24
NO334441B1 (no) 2014-03-03
US20040248924A1 (en) 2004-12-09
ES2259098T3 (es) 2006-09-16
US8450339B2 (en) 2013-05-28
EA008165B1 (ru) 2007-04-27
CA2460140C (en) 2009-09-01
DK1446119T3 (da) 2006-07-10
HUP0402075A2 (hu) 2005-02-28
CA2460140A1 (en) 2003-03-27
DE60209511D1 (de) 2006-04-27
HUP0402075A3 (en) 2008-04-28
PT1446119E (pt) 2006-07-31
EA200400444A1 (ru) 2005-02-24
HU226527B1 (hu) 2009-03-30
BR0212586A (pt) 2004-10-13
PL208686B1 (pl) 2011-05-31
CN1555263A (zh) 2004-12-15
US7652030B2 (en) 2010-01-26
WO2003024433A3 (en) 2004-06-10
ATE318601T1 (de) 2006-03-15
NO20041070L (no) 2004-05-18

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C56 Change in the name or address of the patentee

Owner name: NYCOMED DENMARK CO., LTD.

Free format text: FORMER NAME: NYCOMED DANMARK AS

CP01 Change in the name or title of a patent holder

Address after: DanMai Los Gerd

Patentee after: NYCOMED DANMARK APS

Address before: DanMai Los Gerd

Patentee before: Denmark Nykomin Co.,Ltd.

C56 Change in the name or address of the patentee

Owner name: TAKEDA PHARMACEUTICALS LTD.

Free format text: FORMER NAME: NYCOMED DANMARK AS

CP01 Change in the name or title of a patent holder

Address after: DanMai Los Gerd

Patentee after: Takeda pharmaceutical Limited by Share Ltd.

Address before: DanMai Los Gerd

Patentee before: Nycomed Danmark APS

C56 Change in the name or address of the patentee
CP02 Change in the address of a patent holder

Address after: Tasmania, Denmark

Patentee after: Takeda pharmaceutical Limited by Share Ltd.

Address before: DanMai Los Gerd

Patentee before: Takeda pharmaceutical Limited by Share Ltd.

CX01 Expiry of patent term

Granted publication date: 20061220

CX01 Expiry of patent term