JP4500045B2 - 感冒の治療のための組成物 - Google Patents
感冒の治療のための組成物 Download PDFInfo
- Publication number
- JP4500045B2 JP4500045B2 JP2003528530A JP2003528530A JP4500045B2 JP 4500045 B2 JP4500045 B2 JP 4500045B2 JP 2003528530 A JP2003528530 A JP 2003528530A JP 2003528530 A JP2003528530 A JP 2003528530A JP 4500045 B2 JP4500045 B2 JP 4500045B2
- Authority
- JP
- Japan
- Prior art keywords
- salt
- acid
- xylometazoline
- ipratropium
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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- 229960001095 xylometazoline hydrochloride Drugs 0.000 claims abstract description 60
- YGWFCQYETHJKNX-UHFFFAOYSA-N 2-[(4-tert-butyl-2,6-dimethylphenyl)methyl]-4,5-dihydro-1h-imidazol-3-ium;chloride Chemical compound [Cl-].CC1=CC(C(C)(C)C)=CC(C)=C1CC1=NCC[NH2+]1 YGWFCQYETHJKNX-UHFFFAOYSA-N 0.000 claims abstract description 59
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- 235000002639 sodium chloride Nutrition 0.000 claims description 137
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- Engineering & Computer Science (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Saccharide Compounds (AREA)
- Polyurethanes Or Polyureas (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200101356 | 2001-09-18 | ||
| PCT/IB2002/003828 WO2003024433A2 (en) | 2001-09-18 | 2002-09-18 | Compositions for treatment of common cold, comprising ipratropium and xylometazoline |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005505569A JP2005505569A (ja) | 2005-02-24 |
| JP2005505569A5 JP2005505569A5 (https=) | 2005-12-15 |
| JP4500045B2 true JP4500045B2 (ja) | 2010-07-14 |
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| Application Number | Title | Priority Date | Filing Date |
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| JP2003528530A Expired - Lifetime JP4500045B2 (ja) | 2001-09-18 | 2002-09-18 | 感冒の治療のための組成物 |
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|---|---|
| US (2) | US7652030B2 (https=) |
| EP (2) | EP1446119B1 (https=) |
| JP (1) | JP4500045B2 (https=) |
| KR (1) | KR100810872B1 (https=) |
| CN (1) | CN1290502C (https=) |
| AT (1) | ATE318601T1 (https=) |
| BR (1) | BRPI0212586B8 (https=) |
| CA (1) | CA2460140C (https=) |
| DE (1) | DE60209511T2 (https=) |
| DK (1) | DK1446119T3 (https=) |
| EA (1) | EA008165B1 (https=) |
| ES (1) | ES2259098T3 (https=) |
| HU (1) | HU226527B1 (https=) |
| MX (1) | MXPA04002500A (https=) |
| NO (1) | NO334441B1 (https=) |
| NZ (1) | NZ531792A (https=) |
| PL (1) | PL208686B1 (https=) |
| PT (1) | PT1446119E (https=) |
| SI (1) | SI1446119T1 (https=) |
| WO (1) | WO2003024433A2 (https=) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030055026A1 (en) | 2001-04-17 | 2003-03-20 | Dey L.P. | Formoterol/steroid bronchodilating compositions and methods of use thereof |
| DE60209511T2 (de) * | 2001-09-18 | 2006-10-05 | Nycomed Danmark Aps | Zusammensetzungen zur behandlung des schnupfens, welche ipratropium und xylometazolin enthalten |
| TWI359675B (en) | 2003-07-10 | 2012-03-11 | Dey L P | Bronchodilating β-agonist compositions |
| RU2006132043A (ru) * | 2004-02-06 | 2008-03-20 | МЕДА Фарма ГмбХ унд Ко.КГ (DE) | Комбинация и фармацевтический препарат для лечения ринита |
| WO2005084330A2 (en) * | 2004-03-02 | 2005-09-15 | Synergia Pharma, Inc. | Compositions and methods for treating nasal congestion |
| DE102004049008A1 (de) * | 2004-10-05 | 2006-04-06 | Merck Patent Gmbh | Neue Verwendung für α-Sympathomimetika mit 2-Imidazolinstruktur |
| MX2007007836A (es) * | 2004-12-27 | 2007-08-20 | Eisai R&D Man Co Ltd | Metodo para estabilizar un farmaco anti-demencia. |
| DE102006023770A1 (de) * | 2006-05-20 | 2007-11-22 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Treibgasfreie Aerosolformulierung für die Inhalation |
| EP2077132A1 (en) | 2008-01-02 | 2009-07-08 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dispensing device, storage device and method for dispensing a formulation |
| US20090270472A1 (en) * | 2008-04-25 | 2009-10-29 | Kenneth Gould | Method to use oxymetazoline to interrupt the development of the common cold syndrome |
| EP2414560B1 (de) | 2009-03-31 | 2013-10-23 | Boehringer Ingelheim International GmbH | Verfahren zur beschichtung einer oberfläche eines bauteils |
| JP5763053B2 (ja) | 2009-05-18 | 2015-08-12 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | アダプタ、吸入器具及びアトマイザ |
| WO2011064163A1 (en) | 2009-11-25 | 2011-06-03 | Boehringer Ingelheim International Gmbh | Nebulizer |
| BR112012012475B1 (pt) | 2009-11-25 | 2020-03-03 | Boehringer Ingelheim International Gmbh | Nebulizador |
| US10016568B2 (en) | 2009-11-25 | 2018-07-10 | Boehringer Ingelheim International Gmbh | Nebulizer |
| WO2011160932A1 (en) | 2010-06-24 | 2011-12-29 | Boehringer Ingelheim International Gmbh | Nebulizer |
| EP2694220B1 (de) | 2011-04-01 | 2020-05-06 | Boehringer Ingelheim International GmbH | Medizinisches gerät mit behälter |
| US9827384B2 (en) | 2011-05-23 | 2017-11-28 | Boehringer Ingelheim International Gmbh | Nebulizer |
| WO2013152894A1 (de) | 2012-04-13 | 2013-10-17 | Boehringer Ingelheim International Gmbh | Zerstäuber mit kodiermitteln |
| WO2014158119A1 (en) * | 2013-03-29 | 2014-10-02 | Santa Farma İlaç Sanayi̇ A.Ş | Aqueous solution composition containing ipratropium and oxymetazoline |
| WO2014158118A1 (en) * | 2013-03-29 | 2014-10-02 | Santa Farma İlaç Sanayi̇ A.Ş. | Suspension composition containing ipratropium and oxymetazoline |
| ES2836977T3 (es) | 2013-08-09 | 2021-06-28 | Boehringer Ingelheim Int | Nebulizador |
| JP6643231B2 (ja) | 2013-08-09 | 2020-02-12 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ネブライザ |
| WO2015054359A1 (en) * | 2013-10-08 | 2015-04-16 | Ebadi Mark A | Methods and compositions for symptomatic reflief of the common cold |
| WO2015169430A1 (en) | 2014-05-07 | 2015-11-12 | Boehringer Ingelheim International Gmbh | Nebulizer |
| IL247927B (en) | 2014-05-07 | 2022-09-01 | Boehringer Ingelheim Int | Container, a device that turns a liquid into a fine spray and use |
| CN116036425A (zh) | 2014-05-07 | 2023-05-02 | 勃林格殷格翰国际有限公司 | 喷雾器、指示器装置及容器 |
| US20170348230A1 (en) * | 2014-12-24 | 2017-12-07 | Jadran-Galenski Laboratorij D.D | A nasal composition containing sea water as stability-improving excipient |
| MX383771B (es) * | 2015-12-02 | 2025-03-14 | Pablo Cortes Borrego | Combinación de oximetazolina e ipratropio en aplicación tópica nasal para el tratamiento de la tos. |
| US20220031739A1 (en) * | 2020-07-31 | 2022-02-03 | Eye Therapies Llc | Anti-viral compositions and methods of use thereof |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69229880T2 (de) * | 1991-11-19 | 2000-05-04 | The University Of Virginia Patent Foundation, Charlottesville | Kombinierte virustatikum-antimediator-behandlung (covam) von gewöhnlichen erkältungen |
| IL101056A (en) | 1992-02-24 | 1997-03-18 | Res & Dev Co Ltd | Composition for nasal treatment |
| GB9218834D0 (en) | 1992-09-05 | 1992-10-21 | Procter & Gamble | Nasal spray products |
| ATE177941T1 (de) * | 1992-12-09 | 1999-04-15 | Boehringer Ingelheim Pharma | Stabilisierte medizinische aerosollösungen |
| EP0780127A1 (en) | 1995-12-19 | 1997-06-25 | The Procter & Gamble Company | A nasal spray containing a steroid and a antihistamine |
| DE19653969A1 (de) | 1996-12-20 | 1998-06-25 | Boehringer Ingelheim Kg | Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole |
| WO1998048839A1 (en) * | 1997-04-30 | 1998-11-05 | Warner-Lambert Company | Topical nasal antiinflammatory compositions |
| CA2311530C (en) * | 1998-01-30 | 2008-06-10 | Novartis Consumer Health S.A. | Nasal solutions |
| BR9911351A (pt) | 1998-06-18 | 2001-03-13 | Boehringer Ingelheim Pharma | Formulações farmacêuticas para aerossóis com duas ou mais substâncias ativas |
| AU765736B2 (en) | 1999-06-22 | 2003-09-25 | Boehringer Ingelheim International Gmbh | Stable xylometazoline and oxymetazoline solution |
| DE60209511T2 (de) * | 2001-09-18 | 2006-10-05 | Nycomed Danmark Aps | Zusammensetzungen zur behandlung des schnupfens, welche ipratropium und xylometazolin enthalten |
-
2002
- 2002-09-18 DE DE60209511T patent/DE60209511T2/de not_active Expired - Lifetime
- 2002-09-18 EP EP02765268A patent/EP1446119B1/en not_active Expired - Lifetime
- 2002-09-18 DK DK02765268T patent/DK1446119T3/da active
- 2002-09-18 ES ES02765268T patent/ES2259098T3/es not_active Expired - Lifetime
- 2002-09-18 PL PL370536A patent/PL208686B1/pl unknown
- 2002-09-18 WO PCT/IB2002/003828 patent/WO2003024433A2/en not_active Ceased
- 2002-09-18 SI SI200230311T patent/SI1446119T1/sl unknown
- 2002-09-18 HU HU0402075A patent/HU226527B1/hu unknown
- 2002-09-18 MX MXPA04002500A patent/MXPA04002500A/es active IP Right Grant
- 2002-09-18 EP EP06075452A patent/EP1661570A3/en not_active Withdrawn
- 2002-09-18 US US10/489,655 patent/US7652030B2/en not_active Expired - Lifetime
- 2002-09-18 CA CA002460140A patent/CA2460140C/en not_active Expired - Lifetime
- 2002-09-18 BR BRPI0212586A patent/BRPI0212586B8/pt not_active IP Right Cessation
- 2002-09-18 CN CNB028182871A patent/CN1290502C/zh not_active Expired - Lifetime
- 2002-09-18 AT AT02765268T patent/ATE318601T1/de active
- 2002-09-18 JP JP2003528530A patent/JP4500045B2/ja not_active Expired - Lifetime
- 2002-09-18 EA EA200400444A patent/EA008165B1/ru unknown
- 2002-09-18 PT PT02765268T patent/PT1446119E/pt unknown
- 2002-09-18 KR KR1020047003882A patent/KR100810872B1/ko not_active Expired - Lifetime
- 2002-09-18 NZ NZ531792A patent/NZ531792A/en not_active IP Right Cessation
-
2004
- 2004-03-12 NO NO20041070A patent/NO334441B1/no not_active IP Right Cessation
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2009
- 2009-12-11 US US12/654,145 patent/US8450339B2/en not_active Expired - Fee Related
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