EA200400444A1 - Композиции для лечения простуды - Google Patents

Композиции для лечения простуды

Info

Publication number
EA200400444A1
EA200400444A1 EA200400444A EA200400444A EA200400444A1 EA 200400444 A1 EA200400444 A1 EA 200400444A1 EA 200400444 A EA200400444 A EA 200400444A EA 200400444 A EA200400444 A EA 200400444A EA 200400444 A1 EA200400444 A1 EA 200400444A1
Authority
EA
Eurasian Patent Office
Prior art keywords
compositions
salt
combination
treatment
local
Prior art date
Application number
EA200400444A
Other languages
English (en)
Other versions
EA008165B1 (ru
Inventor
Ханна Аннетт Моэсгард
Карин Ловенштейн Кристенсен
Original Assignee
Никомед Данмарк Апс
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Никомед Данмарк Апс filed Critical Никомед Данмарк Апс
Publication of EA200400444A1 publication Critical patent/EA200400444A1/ru
Publication of EA008165B1 publication Critical patent/EA008165B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Cosmetics (AREA)

Abstract

Описаны новые стабильные композиции, содержащие комбинацию сосудосуживающего средства местного действия и антихолинергического средства местного действия. Предпочтительно, композиция содержит ипратропиум или его соль в комбинации с ксилометазолина гидрохлоридом или его солью. После местного введения таких композиций в слизистую носа существенно снижаются симптомы ринореи у лиц, страдающих простудой.Отчет о международном поиске был опубликован 2004.06.10.
EA200400444A 2001-09-18 2002-09-18 Композиции для лечения простуды EA008165B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200101356 2001-09-18
PCT/IB2002/003828 WO2003024433A2 (en) 2001-09-18 2002-09-18 Compositions for treatment of common cold, comprising ipratropium and xylometazoline

Publications (2)

Publication Number Publication Date
EA200400444A1 true EA200400444A1 (ru) 2005-02-24
EA008165B1 EA008165B1 (ru) 2007-04-27

Family

ID=8160714

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200400444A EA008165B1 (ru) 2001-09-18 2002-09-18 Композиции для лечения простуды

Country Status (21)

Country Link
US (2) US7652030B2 (ru)
EP (2) EP1661570A3 (ru)
JP (1) JP4500045B2 (ru)
KR (1) KR100810872B1 (ru)
CN (1) CN1290502C (ru)
AT (1) ATE318601T1 (ru)
BR (1) BRPI0212586B8 (ru)
CA (1) CA2460140C (ru)
DE (1) DE60209511T2 (ru)
DK (1) DK1446119T3 (ru)
EA (1) EA008165B1 (ru)
ES (1) ES2259098T3 (ru)
HK (1) HK1067984A1 (ru)
HU (1) HU226527B1 (ru)
MX (1) MXPA04002500A (ru)
NO (1) NO334441B1 (ru)
NZ (1) NZ531792A (ru)
PL (1) PL208686B1 (ru)
PT (1) PT1446119E (ru)
SI (1) SI1446119T1 (ru)
WO (1) WO2003024433A2 (ru)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030055026A1 (en) 2001-04-17 2003-03-20 Dey L.P. Formoterol/steroid bronchodilating compositions and methods of use thereof
BRPI0212586B8 (pt) * 2001-09-18 2021-05-25 Nycomed Danmark Aps composição na forma de uma solução aquosa, e, uso da mesma
TWI359675B (en) * 2003-07-10 2012-03-11 Dey L P Bronchodilating β-agonist compositions
JP2007520509A (ja) * 2004-02-06 2007-07-26 メダ ファーマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディト ゲゼルシャフト 抗コリン薬による、又は抗ヒスタミン薬、ホスホジエステラーゼ４、又はコルチコステロイドとの組み合わせによる鼻炎治療薬
WO2005084330A2 (en) * 2004-03-02 2005-09-15 Synergia Pharma, Inc. Compositions and methods for treating nasal congestion
DE102004049008A1 (de) * 2004-10-05 2006-04-06 Merck Patent Gmbh Neue Verwendung für α-Sympathomimetika mit 2-Imidazolinstruktur
US8481565B2 (en) * 2004-12-27 2013-07-09 Eisai R&D Management Co., Ltd. Method for stabilizing anti-dementia drug
DE102006023770A1 (de) * 2006-05-20 2007-11-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Treibgasfreie Aerosolformulierung für die Inhalation
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
US20090270472A1 (en) * 2008-04-25 2009-10-29 Kenneth Gould Method to use oxymetazoline to interrupt the development of the common cold syndrome
EP2414560B1 (de) 2009-03-31 2013-10-23 Boehringer Ingelheim International GmbH Verfahren zur beschichtung einer oberfläche eines bauteils
WO2010133294A2 (de) 2009-05-18 2010-11-25 Boehringer Ingelheim International Gmbh Adapter, inhalationseinrichtung und zerstäuber
JP5658268B2 (ja) 2009-11-25 2015-01-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
CN102686260B (zh) 2009-11-25 2014-10-01 贝林格尔.英格海姆国际有限公司 喷雾器
US9943654B2 (en) 2010-06-24 2018-04-17 Boehringer Ingelheim International Gmbh Nebulizer
WO2012130757A1 (de) 2011-04-01 2012-10-04 Boehringer Ingelheim International Gmbh Medizinisches gerät mit behälter
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
WO2014158118A1 (en) * 2013-03-29 2014-10-02 Santa Farma İlaç Sanayi̇ A.Ş. Suspension composition containing ipratropium and oxymetazoline
EP2978407B1 (en) * 2013-03-29 2020-05-06 Santa Farma Ilaç Sanayi A.S. Aqueous solution composition containing ipratropium and oxymetazoline
ES2836977T3 (es) 2013-08-09 2021-06-28 Boehringer Ingelheim Int Nebulizador
US9744313B2 (en) 2013-08-09 2017-08-29 Boehringer Ingelheim International Gmbh Nebulizer
WO2015054359A1 (en) * 2013-10-08 2015-04-16 Ebadi Mark A Methods and compositions for symptomatic reflief of the common cold
EP3139979B1 (en) 2014-05-07 2023-07-05 Boehringer Ingelheim International GmbH Unit, nebulizer and method
UA121114C2 (uk) 2014-05-07 2020-04-10 Бьорінгер Інгельхайм Інтернаціональ Гмбх Небулайзер, індикаторний пристрій і контейнер
ES2874029T3 (es) 2014-05-07 2021-11-04 Boehringer Ingelheim Int Nebulizador
WO2016102984A1 (en) 2014-12-24 2016-06-30 Jadran - Galenski Laboratorij D.D. A nasal composition containing sea water as stability-improving excipient
MX2015016549A (es) * 2015-12-02 2017-06-01 Cortés Borrego Pablo Combinacion de oximetazolina e ipratropio en aplicacion topica nasal para el tratamiento de la tos.
US20220031739A1 (en) * 2020-07-31 2022-02-03 Eye Therapies Llc Anti-viral compositions and methods of use thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993009764A1 (en) * 1991-11-19 1993-05-27 Center For Innovative Technology Combined virustatic antimediator (covam) treatment of common colds
IL101056A (en) 1992-02-24 1997-03-18 Res & Dev Co Ltd Composition for nasal treatment
GB9218834D0 (en) 1992-09-05 1992-10-21 Procter & Gamble Nasal spray products
SK280911B6 (sk) 1992-12-09 2000-09-12 Boehringer Ingelheim Pharmaceuticals, Inc. Farmaceutický prostriedok
EP0780127A1 (en) 1995-12-19 1997-06-25 The Procter & Gamble Company A nasal spray containing a steroid and a antihistamine
DE19653969A1 (de) 1996-12-20 1998-06-25 Boehringer Ingelheim Kg Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole
CN1253508A (zh) * 1997-04-30 2000-05-17 沃尼尔－朗伯公司 局部鼻用抗炎组合物
EP1051155B1 (en) * 1998-01-30 2002-06-26 Novartis Consumer Health S.A. Nasal solutions
HU229064B1 (en) 1998-06-18 2013-07-29 Boehringer Ingelheim Pharma Pharmaceutical formulations for aerosols with two or more active substances
HUP0201700A3 (en) * 1999-06-22 2003-02-28 Boehringer Ingelheim Int Stable xylometazoline and oxymetazoline solutions, their use for producing pharmaceutical compositions and pharmaceutical compositions containing them
BRPI0212586B8 (pt) * 2001-09-18 2021-05-25 Nycomed Danmark Aps composição na forma de uma solução aquosa, e, uso da mesma

Also Published As

Publication number Publication date
BRPI0212586B8 (pt) 2021-05-25
JP4500045B2 (ja) 2010-07-14
PL208686B1 (pl) 2011-05-31
EP1446119A2 (en) 2004-08-18
BR0212586B1 (pt) 2013-11-19
CN1290502C (zh) 2006-12-20
NO20041070L (no) 2004-05-18
HK1067984A1 (en) 2005-04-22
CA2460140C (en) 2009-09-01
MXPA04002500A (es) 2004-11-22
NZ531792A (en) 2006-02-24
DE60209511T2 (de) 2006-10-05
PL370536A1 (en) 2005-05-30
US20100093783A1 (en) 2010-04-15
EP1661570A2 (en) 2006-05-31
CA2460140A1 (en) 2003-03-27
HUP0402075A3 (en) 2008-04-28
EA008165B1 (ru) 2007-04-27
HUP0402075A2 (hu) 2005-02-28
KR100810872B1 (ko) 2008-03-06
US8450339B2 (en) 2013-05-28
US20040248924A1 (en) 2004-12-09
WO2003024433A2 (en) 2003-03-27
ES2259098T3 (es) 2006-09-16
DE60209511D1 (de) 2006-04-27
NO334441B1 (no) 2014-03-03
WO2003024433A3 (en) 2004-06-10
SI1446119T1 (sl) 2006-08-31
CN1555263A (zh) 2004-12-15
KR20040049849A (ko) 2004-06-12
HU226527B1 (hu) 2009-03-30
DK1446119T3 (da) 2006-07-10
JP2005505569A (ja) 2005-02-24
EP1661570A3 (en) 2012-10-24
US7652030B2 (en) 2010-01-26
BR0212586A (pt) 2004-10-13
PT1446119E (pt) 2006-07-31
ATE318601T1 (de) 2006-03-15
EP1446119B1 (en) 2006-03-01

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Legal Events

Date Code Title Description
PD4A Registration of transfer of a eurasian patent in accordance with the succession in title
QB4A Registration of a licence in a contracting state