CN1282745C - 微生物油的分离 - Google Patents

微生物油的分离 Download PDF

Info

Publication number
CN1282745C
CN1282745C CNB018143016A CN01814301A CN1282745C CN 1282745 C CN1282745 C CN 1282745C CN B018143016 A CNB018143016 A CN B018143016A CN 01814301 A CN01814301 A CN 01814301A CN 1282745 C CN1282745 C CN 1282745C
Authority
CN
China
Prior art keywords
oil
polyunsaturated fatty
cell
cell wall
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CNB018143016A
Other languages
English (en)
Chinese (zh)
Other versions
CN1447860A (zh
Inventor
H·L·比杰
A·沙普
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koninklijke DSM NV
Original Assignee
DSM NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8173160&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN1282745(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by DSM NV filed Critical DSM NV
Publication of CN1447860A publication Critical patent/CN1447860A/zh
Application granted granted Critical
Publication of CN1282745C publication Critical patent/CN1282745C/zh
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • C12P7/6445Glycerides
    • C12P7/6463Glycerides obtained from glyceride producing microorganisms, e.g. single cell oil
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23DEDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
    • A23D9/00Other edible oils or fats, e.g. shortenings or cooking oils
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11BPRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B1/00Production of fats or fatty oils from raw materials
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11BPRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B1/00Production of fats or fatty oils from raw materials
    • C11B1/02Pretreatment
    • C11B1/025Pretreatment by enzymes or microorganisms, living or dead
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11BPRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B1/00Production of fats or fatty oils from raw materials
    • C11B1/06Production of fats or fatty oils from raw materials by pressing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • C12P7/6445Glycerides
    • C12P7/6472Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Fats And Perfumes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
CNB018143016A 2000-08-02 2001-08-01 微生物油的分离 Expired - Lifetime CN1282745C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00306601A EP1178118A1 (en) 2000-08-02 2000-08-02 Isolation of microbial oils
EP00306601.6 2000-08-02

Publications (2)

Publication Number Publication Date
CN1447860A CN1447860A (zh) 2003-10-08
CN1282745C true CN1282745C (zh) 2006-11-01

Family

ID=8173160

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB018143016A Expired - Lifetime CN1282745C (zh) 2000-08-02 2001-08-01 微生物油的分离

Country Status (19)

Country Link
US (1) US7431952B2 (cg-RX-API-DMAC7.html)
EP (2) EP1178118A1 (cg-RX-API-DMAC7.html)
JP (4) JP2004504849A (cg-RX-API-DMAC7.html)
KR (6) KR20030059086A (cg-RX-API-DMAC7.html)
CN (1) CN1282745C (cg-RX-API-DMAC7.html)
AT (1) ATE470719T1 (cg-RX-API-DMAC7.html)
AU (2) AU9371101A (cg-RX-API-DMAC7.html)
BR (1) BR0112942A (cg-RX-API-DMAC7.html)
CA (2) CA2742152C (cg-RX-API-DMAC7.html)
DE (1) DE60142339D1 (cg-RX-API-DMAC7.html)
DK (1) DK1305440T3 (cg-RX-API-DMAC7.html)
EA (1) EA006979B1 (cg-RX-API-DMAC7.html)
ES (1) ES2357614T3 (cg-RX-API-DMAC7.html)
IL (2) IL154146A0 (cg-RX-API-DMAC7.html)
MX (1) MXPA03000878A (cg-RX-API-DMAC7.html)
NO (1) NO20030510L (cg-RX-API-DMAC7.html)
NZ (1) NZ523884A (cg-RX-API-DMAC7.html)
WO (1) WO2002010423A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA200300787B (cg-RX-API-DMAC7.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI869742B (zh) * 2022-01-27 2025-01-11 南韓商Cj第一製糖股份有限公司 用於自微藻類培養基萃取油之方法

Families Citing this family (111)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE485385T1 (de) 2000-01-19 2010-11-15 Martek Biosciences Corp Lösungsmittelfreies extraktionsverfahren
ATE430794T1 (de) * 2001-03-09 2009-05-15 Nestle Sa Öl, das langkettige, mehrfach ungesättigte fettsäuren aus biomassen enthält, verfahren zur herstellung, lebensmittel, nahrungsmittelzusammensetzung, kosmetische oder pharmazeutische zusammensetzung, die dieses enthält
EP2266525B1 (en) * 2002-05-03 2012-07-11 Martek Biosciences Corporation High quality lipids and methods for producing by enzymatic liberation from biomass
WO2004001021A1 (en) 2002-06-19 2003-12-31 Dsm Ip Assets B.V. Pasteurisation process for microbial cells and microbial oil
EP1396533B1 (fr) 2002-09-04 2008-09-03 Nestec S.A. Procédé de préparation d'une huile contenant un ou des acides gras polyinsaturé(s) à longue chaine issus de biomasse, aliment, composition nutritionnelle, cosmétique ou pharmaceutique la contenant
US7601858B2 (en) * 2004-08-17 2009-10-13 Gs Cleantech Corporation Method of processing ethanol byproducts and related subsystems
WO2006046943A2 (en) * 2004-10-22 2006-05-04 Martek Biosciences Corporation Methods for producing lipids by liberation from biomass
DE102005003624A1 (de) * 2005-01-26 2006-07-27 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Herstellung und Anwendung eines antioxidativ wirksamen Extraktes aus Crypthecodinium sp.
US9108140B2 (en) 2005-03-16 2015-08-18 Gs Cleantech Corporation Method and systems for washing ethanol production byproducts to improve oil recovery
EP3238543B1 (en) 2005-06-07 2019-03-20 DSM Nutritional Products AG Eukaryotic microorganisms for producing lipids and antioxidants
EP1903883A4 (en) * 2005-07-01 2010-06-23 Martek Biosciences Corp OIL PRODUCT CONTAINING MULTIPLE UNSATURATED FATTY ACIDS AND ITS USES AND MANUFACTURING
WO2007063691A1 (ja) * 2005-11-29 2007-06-07 Sanyo Chemical Industries, Ltd. 溶菌剤
CA2659603C (en) 2006-08-01 2017-03-07 Ocean Nutrition Canada Limited Oil producing microbes and methods of modification thereof
US8404004B2 (en) 2006-12-29 2013-03-26 Genifuel Corporation Process of producing oil from algae using biological rupturing
BRPI0811967B1 (pt) 2007-06-01 2023-01-17 Terravia Holdings, Inc Microalga chlorella ou prototheca e método para produção de lipídios microbianos
US8343753B2 (en) * 2007-11-01 2013-01-01 Wake Forest University School Of Medicine Compositions, methods, and kits for polyunsaturated fatty acids from microalgae
US8043496B1 (en) 2008-03-18 2011-10-25 Peter Allen Schuh System for extracting oil from algae
EP2145942A1 (de) * 2008-07-15 2010-01-20 Lonza Ltd. Verfahren zur Isolierung von Ölen aus Zellen und Biomasse
US8815570B2 (en) * 2008-10-02 2014-08-26 Feyecon B.V. Microalgae extract containing omega 3-polyunsaturated fatty acids and method for extracting oil from micro-organisms
US20100303989A1 (en) 2008-10-14 2010-12-02 Solazyme, Inc. Microalgal Flour
US20160324167A1 (en) 2008-10-14 2016-11-10 Terravia Holdings, Inc. Novel microalgal food compositions
CA2745129C (en) 2008-11-28 2019-05-07 Solazyme, Inc. Production of tailored oils in heterotrophic microorganisms
US8207363B2 (en) 2009-03-19 2012-06-26 Martek Biosciences Corporation Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
CN101817738B (zh) * 2009-11-13 2013-08-14 厦门汇盛生物有限公司 一种从藻类和真菌细胞中破壁提取dha的方法
CN102884201B (zh) 2010-01-19 2016-04-13 帝斯曼知识产权资产管理有限公司 生产二十碳五烯酸的微生物、脂肪酸组成物及其制作方法与用途
US8187861B1 (en) 2010-01-26 2012-05-29 Allen John Schuh Phosphate removal-recovery and biofuel feedstock system
CN101805670A (zh) * 2010-04-09 2010-08-18 上海中器环保科技有限公司 一种微生物柴油的制备方法
WO2011133181A1 (en) * 2010-04-20 2011-10-27 Origin Oil, Inc. Systems, apparatuses, and methods for extracting non-polar lipids from an a aqueous algae slurry and lipids produced therefrom
CA3039432A1 (en) 2010-05-28 2011-12-01 Corbion Biotech, Inc. Tailored oils produced from recombinant heterotrophic microorganisms
EP2576801B1 (en) 2010-06-01 2019-10-02 DSM IP Assets B.V. Extraction of lipid from cells and products therefrom
NL2004832C2 (en) * 2010-06-07 2011-12-08 Evodos B V Separating biomass from an aqueous medium.
US9028696B2 (en) 2010-07-26 2015-05-12 Sapphire Energy, Inc. Process for the recovery of oleaginous compounds from biomass
CN103080325B (zh) 2010-07-26 2014-08-06 蓝宝石能源公司 用于从生物质回收油质化合物的方法
US8906236B2 (en) 2010-07-26 2014-12-09 Sapphire Energy, Inc. Process for the recovery of oleaginous compounds and nutrients from biomass
EP2619297A1 (en) * 2010-09-21 2013-07-31 Shell Internationale Research Maatschappij B.V. Process for separation of a mixture containing a microbial oil and a microbial substance
US9066527B2 (en) 2010-11-03 2015-06-30 Solazyme, Inc. Microbial oils with lowered pour points, dielectric fluids produced therefrom, and related methods
US20120329138A1 (en) 2010-12-23 2012-12-27 Shell Oil Company Process for separation of a mixture containing a microbial substance and a liquid
EP2670855B1 (en) 2011-02-02 2019-08-21 Corbion Biotech, Inc. Tailored oils produced from recombinant oleaginous microorganisms
US8999663B2 (en) * 2011-02-11 2015-04-07 E L Du Pont De Nemours And Company Method for obtaining a lipid-containing composition from microbial biomass
US20130045226A1 (en) * 2011-02-11 2013-02-21 E I Du Pont De Nemours And Company Method for forming and extracting solid pellets comprising oil-containing microbes
WO2012154626A1 (en) 2011-05-06 2012-11-15 Solazyme, Inc. Genetically engineered microorganisms that metabolize xylose
FR2975705B1 (fr) 2011-05-27 2014-12-26 Roquette Freres Procede d'extraction du squalene a partir de microalgues
CN103930104A (zh) 2011-07-21 2014-07-16 帝斯曼知识产权资产管理有限公司 脂肪酸组合物
US8986977B2 (en) * 2011-12-30 2015-03-24 Alliance For Sustainable Energy, Llc Disruption of cell walls for enhanced lipid recovery
US12268718B2 (en) * 2012-01-16 2025-04-08 Labyrinth Holdings Llc Control of cellular redox levels
KR20140121818A (ko) 2012-01-16 2014-10-16 엘라자베스 맥켄나 간 질환들 및 장애들의 치료를 위한 조성물들 및 방법들
US9309544B2 (en) 2012-04-10 2016-04-12 Kao Corporation Method for producing fatty acid ester
AU2013249172C1 (en) 2012-04-18 2017-08-10 Corbion Biotech, Inc. Tailored oils
KR101432277B1 (ko) * 2012-05-22 2014-08-21 한국과학기술원 양이온성 고분자를 이용한 미세조류로부터 지질의 추출방법 및 추출된 지질을 이용한 바이오디젤 제조방법
CN102702777B (zh) * 2012-06-07 2014-03-19 北京林业大学 一种酶法水解从植物原料中提取水溶性类胡萝卜素的方法
WO2014041985A1 (ja) * 2012-09-11 2014-03-20 Dic株式会社 液晶表示装置
HK1213017A1 (zh) 2012-09-21 2016-06-24 Elizabeth Mckenna 天然存在的cpg寡聚核苷酸组合物及其治疗应用
CA2895684C (en) * 2012-12-19 2020-04-14 Buckman Laboratories International, Inc. Methods and systems for bio-oil recovery and separation aids therefor
US10098371B2 (en) 2013-01-28 2018-10-16 Solazyme Roquette Nutritionals, LLC Microalgal flour
EP2762008A1 (de) * 2013-02-05 2014-08-06 Evonik Industries AG Verbesserung der Bioverfügbarkeit von Wertstoffen aus Mikroorganismen durch Verwendung eines Rotor-Stator Systems für den Zellaufschluss
WO2014141098A1 (en) 2013-03-13 2014-09-18 Dsm Nutritional Products Ag Engineering microorganisms
KR102023756B1 (ko) * 2013-05-14 2019-09-23 에스케이이노베이션 주식회사 신규 트라우스토키트리드〔Thraustochytrid〕 계 미세조류 트라우스토키트리움〔Thraustochytrium〕sp.LA6〔KCTC12389BP〕및 이를 이용한 바이오오일의 생산방법
CN104293475B (zh) * 2013-07-19 2017-07-25 中国石油化工股份有限公司 一种从产油微生物中提取油脂的方法
FR3009619B1 (fr) 2013-08-07 2017-12-29 Roquette Freres Compositions de biomasse de microalgues riches en proteines de qualite sensorielle optimisee
JP6517196B2 (ja) 2013-10-04 2019-05-22 テラヴィア ホールディングス, インコーポレイテッド 調整油
PL3101138T3 (pl) 2013-12-04 2021-10-25 Nippon Suisan Kaisha, Ltd. Olej drobnoustrojowy, sposób wytwarzania oleju drobnoustrojowego, stężony olej drobnoustrojowy oraz sposób wytwarzania stężonego oleju drobnoustrojowego
KR102435268B1 (ko) 2013-12-20 2022-08-22 디에스엠 뉴트리셔널 프라덕츠 아게 미생물로부터 오일을 회수하는 방법
WO2015095690A2 (en) * 2013-12-20 2015-06-25 Dsm Ip Assets B.V. Processes for obtaining microbial oil from microbial cells
TWI698520B (zh) * 2013-12-20 2020-07-11 荷蘭商Dsm智慧財產有限公司 用於從微生物細胞獲得微生物油之方法(三)
EP3083545B1 (en) * 2013-12-20 2023-08-02 DSM IP Assets B.V. Processes for obtaining microbial oil from microbial cells
CN115109804A (zh) * 2013-12-20 2022-09-27 玛拉可再生能源公司 从微生物中回收油的方法
ES2909791T3 (es) * 2013-12-20 2022-05-10 Dsm Ip Assets Bv Procesos para obtener aceite microbiano a partir de células microbianas
MX383112B (es) 2013-12-20 2025-03-13 Dsm Ip Assets Bv Procedimientos para obtener aceite microbiano a partir de células microbianas.
JP2017501705A (ja) * 2013-12-20 2017-01-19 ディーエスエム アイピー アセッツ ビー.ブイ. バイオ燃料の生産に用いられる脂質の抽出プロセス
CN103789083B (zh) * 2014-02-17 2016-01-20 南京工业大学大丰海洋产业研究院 一种真菌油脂提取方法
ES2764273T3 (es) 2014-07-10 2020-06-02 Corbion Biotech Inc Nuevos genes de cetoacil ACP sintasa y uso de los mismos
CN104356097B (zh) * 2014-10-20 2016-06-29 中国科学院广州能源研究所 一种微生物油脂基环氧化物的制备方法
CN104513704B (zh) * 2014-12-11 2018-01-12 湖北福星生物科技有限公司 一种无腥味dha油脂的提取方法
CN104479862A (zh) * 2014-12-31 2015-04-01 嘉必优生物工程(武汉)有限公司 一种提取微生物油脂的方法
AR104042A1 (es) 2015-03-26 2017-06-21 Mara Renewables Corp Producción de alta densidad de biomasa y aceite utilizando glicerol en bruto
EP3302097B1 (en) 2015-05-29 2022-03-23 Cargill, Incorporated Heat treatment to produce glycosides
CN107614677A (zh) 2015-05-29 2018-01-19 嘉吉公司 用于使用多阶段进料生产甜菊醇糖苷的发酵方法
US10815513B2 (en) 2015-05-29 2020-10-27 Cargill, Incorporated Fermentation methods for producing steviol glycosides using high pH and compositions obtained therefrom
US9951326B2 (en) 2015-07-13 2018-04-24 MARA Renewables Corporation Enhancing microbial metabolism of C5 organic carbon
AU2016301190A1 (en) 2015-08-06 2018-02-15 Cargill, Incorporated Fermentation methods for producing steviol glycosides
US10377792B2 (en) 2016-03-16 2019-08-13 The Texas A&M University System Moisture displacement and simultaneous migration of surface-functionalized algae from water to an extraction solvent using ionic polyelectrolytes
US10851395B2 (en) 2016-06-10 2020-12-01 MARA Renewables Corporation Method of making lipids with improved cold flow properties
US11419350B2 (en) 2016-07-01 2022-08-23 Corbion Biotech, Inc. Feed ingredients comprising lysed microbial cells
KR102405390B1 (ko) 2016-07-13 2022-06-03 에보닉 오퍼레이션스 게엠베하 용해된 지질을 함유하는 바이오매스로부터 지질을 분리하는 방법
WO2018122057A1 (en) * 2016-12-27 2018-07-05 Evonik Degussa Gmbh Method of isolating lipids from a lipids containing biomass
ES2872009T3 (es) * 2016-12-27 2021-11-02 Evonik Degussa Gmbh Método de aislamiento de lípidos a partir de una biomasa que contiene lípidos
CN108570484A (zh) * 2017-03-07 2018-09-25 武汉普赛特膜技术循环利用有限公司 一种使用三次发酵法由藻发酵液中纯化富集dha油脂的方法
BR112020000421A2 (pt) * 2017-07-12 2020-09-01 Bunge Global Innovation Llc processo de extração de óleo a partir de biomassa de algas
CN111032878B (zh) * 2017-08-10 2024-03-08 帝斯曼知识产权资产管理有限公司 用于营养油纯化的双重离心过程
WO2019034354A1 (en) 2017-08-17 2019-02-21 Evonik Degussa Gmbh ENHANCED PRODUCTION OF LIPIDS BY LIMITING AT LEAST TWO SOURCES OF NUTRIENT LIMITING
CA3072846A1 (en) 2017-08-17 2019-02-21 Evonik Operations Gmbh Enhanced production of lipids by limitation of at least two limiting nutrient sources
EP3470502A1 (en) 2017-10-13 2019-04-17 Evonik Degussa GmbH Method of separating lipids from a lysed lipids containing biomass
CN107904016B (zh) * 2017-11-10 2021-04-20 海南华研胶原科技股份有限公司 一种红藻精油及其制备方法
EP3527664A1 (en) 2018-02-15 2019-08-21 Evonik Degussa GmbH Method of isolating lipids from a lipids containing biomass
WO2019122030A1 (en) * 2017-12-22 2019-06-27 Dsm Ip Assets B.V. Method of separating lipids from a lysed lipids containing biomass
DE202018000893U1 (de) * 2018-02-19 2019-05-22 Dorothea Jürgens Vorrichtung zur umwelt-und energieschonenden Veraschung von Leichen und Leichenteilen unter vorheriger Separierung der flüssigen Anteile und Verwendung der brennbaren Fraktion zur energetischen Weiterverwendung in und auch ausserhalb der Vorrichtung
EP3536800B1 (en) 2018-03-09 2021-08-04 TU München Extraction of renewable triglycerides from oleaginous microorganisms
EP3775118A4 (en) * 2018-03-30 2022-03-09 DSM IP Assets B.V. Method of reducing emulsion by broth washing
US11414621B2 (en) 2018-05-15 2022-08-16 Evonik Operations Gmbh Method of isolating lipids from a lipids containing biomass with aid of hydrophobic silica
BR112020023222A2 (pt) 2018-05-15 2021-03-23 Evonik Operations Gmbh método de isolamento de lipídios a partir de uma biomassa contendo lipídios lisados por inversão por emulsão
CN108753458A (zh) * 2018-08-03 2018-11-06 梁云 提高微生物油脂稳定性和安全性的精炼工艺
CN108753457A (zh) * 2018-08-03 2018-11-06 梁云 提高微生物油脂稳定性和安全性的方法
FR3085825B1 (fr) 2018-09-14 2021-07-16 Fermentalg Huile de microorganismes riche en acide docosahexaenoique
WO2020186128A1 (en) * 2019-03-14 2020-09-17 Dsm Ip Assets B.V. Methods of obtaining lipids from a microbial cell composition
CN111363614A (zh) * 2019-10-10 2020-07-03 润科生物工程(福建)有限公司 一种非溶剂式提取花生四烯酸油脂的方法
CN110760369A (zh) * 2019-11-08 2020-02-07 润科生物工程(福建)有限公司 一种纯物理提取花生四烯酸油脂的方法
US12359230B2 (en) 2020-04-03 2025-07-15 MARA Renewables Corporation Microbial oils with high levels of omega-3 fatty acids
CN111518611A (zh) * 2020-04-28 2020-08-11 上海容邦企业集团有限公司 沙棘果油复合物及制备方法
CN113684087B (zh) * 2020-05-18 2024-04-19 嘉必优生物技术(武汉)股份有限公司 一种微生物油脂无溶剂提取方法及所得微生物油脂
EP3933016A1 (en) * 2020-06-30 2022-01-05 Evonik Operations GmbH Method of isolating lipids from a lipids containing biomass
FR3111912B1 (fr) 2020-06-24 2025-10-03 Fermentalg Procédé de culture de microorganismes pour l’accumulation de lipides

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB808128A (en) * 1955-12-01 1959-01-28 Nat Res Dev A method of increasing the fatty contents of such micro-organisms as yeasts, bacteria and moulds
DE3248167A1 (de) * 1982-12-27 1984-06-28 Wintershall Ag, 3100 Celle Trehaloselipidtetraester
JPS61170397A (ja) * 1985-01-22 1986-08-01 Agency Of Ind Science & Technol モルテイエレラ属糸状菌体の多段抽出処理方法
JPS62278987A (ja) * 1986-05-26 1987-12-03 Kanegafuchi Chem Ind Co Ltd 酵素反応生成物の回収方法
DK199887D0 (da) * 1987-04-15 1987-04-15 Danisco Bioteknologi As Gaerstamme
JPS63304990A (ja) * 1987-06-04 1988-12-13 Meiji Seika Kaisha Ltd 菌体内有効成分の抽出方法
JPH0198494A (ja) * 1987-10-09 1989-04-17 Agency Of Ind Science & Technol バイオリアクター
KR900004067A (ko) * 1988-08-02 1990-03-27 김용원 100v/220v 겸용 코넥터, 콘센트 및 전압선택 플러그
US5130242A (en) * 1988-09-07 1992-07-14 Phycotech, Inc. Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids
FR2656874B1 (fr) * 1990-01-11 1992-04-03 Commissariat Energie Atomique Procede de production et d'extraction d'anti-oxydants a partir d'une culture de micro-organismes et photobioreacteur pour la mise en óoeuvre de ce procede.
US5658767A (en) * 1991-01-24 1997-08-19 Martek Corporation Arachidonic acid and methods for the production and use thereof
FR2686619B1 (fr) * 1992-01-28 1995-07-13 Commissariat Energie Atomique Procede de production selective de lipides poly-insatures a partir d'une culture de micro-algues du type porphyridium et cuve utilisee dans ce procede.
DE4219360C2 (de) * 1992-06-12 1994-07-28 Milupa Ag Verfahren zur Gewinnung von Lipiden mit einem hohen Anteil von langkettig-hochungesättigten Fettsäuren
CA2197187C (en) * 1994-08-16 2007-03-27 Bernd Best Process for extracting native products which are not water-soluble from native substance mixtures by means of centrifugal force
KR100212644B1 (ko) * 1994-10-29 1999-08-02 토니헬샴 유압식 건설기계의 엔진회전수 제어장치 및 제어방법
US5583019A (en) * 1995-01-24 1996-12-10 Omegatech Inc. Method for production of arachidonic acid
ATE178087T1 (de) * 1995-05-04 1999-04-15 Nestle Sa Verfahren zur fraktionierung von fettsäuren
JPH099981A (ja) * 1995-06-28 1997-01-14 Sekiyu Sangyo Kasseika Center 油水二相系微生物反応における油水分離方法
GB9514649D0 (en) * 1995-07-18 1995-09-13 Zeneca Ltd Extraction of triglycerides from microorganisms
ES2205202T5 (es) * 1996-03-28 2015-11-26 Dsm Ip Assets B.V. Procedimiento para la preparación de una biomasa microbiana granular y aislamiento de compuestos valiosos contenidos en ella
WO1997037032A2 (en) * 1996-03-28 1997-10-09 Gist-Brocades B.V. Preparation of microbial polyunsaturated fatty acid containing oil from pasteurised biomass
ES2362476T3 (es) 1996-07-23 2011-07-06 Nagase Chemtex Corporation Proceso para preparar ácido docosahexanoico y ácido docosapentanoico.
ES2337530T3 (es) 1997-05-02 2010-04-26 Dsm Ip Assets B.V. Aislamiento de cristales de carotenoide a partir de biomasa microbiana.
JP3836231B2 (ja) * 1997-10-17 2006-10-25 日本化学飼料株式会社 ホタテガイ中腸腺から得られる高度不飽和脂肪酸含有油及びその製造方法
WO1999032604A1 (en) 1997-12-23 1999-07-01 Dcv, Inc. Doing Business As Bio-Technical Resources Linoleate isomerase
JP2000041684A (ja) * 1998-07-29 2000-02-15 Daicel Chem Ind Ltd 新規なd−アミノアシラーゼおよびその製造方法、並びに該d−アミノアシラーゼを利用したd−アミノ酸の製造方法
JP2000135096A (ja) * 1998-08-28 2000-05-16 Tadayuki Imanaka 界面活性剤、その生産方法およびその利用方法
ATE485385T1 (de) * 2000-01-19 2010-11-15 Martek Biosciences Corp Lösungsmittelfreies extraktionsverfahren

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI869742B (zh) * 2022-01-27 2025-01-11 南韓商Cj第一製糖股份有限公司 用於自微藻類培養基萃取油之方法

Also Published As

Publication number Publication date
ZA200300787B (en) 2004-02-19
KR20110030661A (ko) 2011-03-23
BR0112942A (pt) 2003-07-08
AU9371101A (en) 2002-02-13
JP2014138598A (ja) 2014-07-31
CA2417571C (en) 2011-09-27
KR20030059086A (ko) 2003-07-07
KR20100019579A (ko) 2010-02-18
WO2002010423A2 (en) 2002-02-07
CA2417571A1 (en) 2002-02-07
US20040067574A1 (en) 2004-04-08
EP1305440A2 (en) 2003-05-02
KR101648277B1 (ko) 2016-08-12
NO20030510D0 (no) 2003-01-31
DE60142339D1 (de) 2010-07-22
JP2016208974A (ja) 2016-12-15
ATE470719T1 (de) 2010-06-15
KR101447912B1 (ko) 2014-11-11
IL154146A (en) 2015-06-30
CA2742152C (en) 2016-04-19
CA2742152A1 (en) 2002-02-07
MXPA03000878A (es) 2003-06-06
ES2357614T3 (es) 2011-04-28
KR20130109249A (ko) 2013-10-07
JP2012019794A (ja) 2012-02-02
EP1305440B1 (en) 2010-06-09
NZ523884A (en) 2004-09-24
WO2002010423A3 (en) 2002-10-03
EA006979B1 (ru) 2006-06-30
KR20120135322A (ko) 2012-12-12
KR20140087054A (ko) 2014-07-08
US7431952B2 (en) 2008-10-07
WO2002010423A8 (en) 2004-05-13
EA200300212A1 (ru) 2003-06-26
IL154146A0 (en) 2003-07-31
AU2001293711B2 (en) 2006-08-24
NO20030510L (no) 2003-03-31
CN1447860A (zh) 2003-10-08
EP1305440B2 (en) 2022-03-30
KR101515317B1 (ko) 2015-04-24
EP1178118A1 (en) 2002-02-06
JP2004504849A (ja) 2004-02-19
DK1305440T3 (da) 2010-09-13

Similar Documents

Publication Publication Date Title
CN1282745C (zh) 微生物油的分离
AU2001293711A1 (en) Isolation of microbial oils
CN100460513C (zh) 无溶剂的提取方法
CN1267174C (zh) 从含油种子和微生物来源提取和冬化脂类的方法
CN109477122B (zh) 从含有产油微生物的发酵液中提取包含多不饱和脂肪酸的微生物油的方法
JP2014177633A (ja) 低ステロール且つ高トリグリセライドの微生物性油を得るための極性溶媒によるステロール抽出
JP2003520046A5 (cg-RX-API-DMAC7.html)
Ingle et al. Acid-assisted oil extraction directly from thraustochytrids fermentation broth and its energy assessment for docosahexaenoic acid-enriched oil production
WO2025101743A1 (en) Nutritional oils having reduced mosh content and methods of making the same
TW202521699A (zh) 具有高epa含量的微生物油及其製備方法
WO2025019424A1 (en) Microbial oils having high epa content and methods of making the same
CN113574045A (zh) 从微生物细胞组合物中获得脂质的方法

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CX01 Expiry of patent term
CX01 Expiry of patent term

Granted publication date: 20061101