CN1261442C - 用于制备草胺膦的方法以及中间体 - Google Patents

用于制备草胺膦的方法以及中间体 Download PDF

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Publication number
CN1261442C
CN1261442C CNB988082616A CN98808261A CN1261442C CN 1261442 C CN1261442 C CN 1261442C CN B988082616 A CNB988082616 A CN B988082616A CN 98808261 A CN98808261 A CN 98808261A CN 1261442 C CN1261442 C CN 1261442C
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China
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formula
alkyl
compound
groups
carbon atoms
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Expired - Lifetime
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CNB988082616A
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English (en)
Chinese (zh)
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CN1267305A (zh
Inventor
L·威尔姆斯
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Bayer CropScience AG
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Hechester Sherin Agricultural Development Co ltd
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Publication of CN1267305A publication Critical patent/CN1267305A/zh
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
    • A01N57/10—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds
    • A01N57/12—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds containing acyclic or cycloaliphatic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/657163—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom
    • C07F9/657172—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom the ring phosphorus atom and one oxygen atom being part of a (thio)phosphinic acid ester: (X = O, S)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/301—Acyclic saturated acids which can have further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/32—Esters thereof
    • C07F9/3205—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/3211—Esters of acyclic saturated acids which can have further substituents on alkyl

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CNB988082616A 1997-08-20 1998-08-08 用于制备草胺膦的方法以及中间体 Expired - Lifetime CN1261442C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19736125.0 1997-08-20
DE19736125A DE19736125A1 (de) 1997-08-20 1997-08-20 Verfahren zur Herstellung von Glufosinate und phosphorhaltige alpha-Aminonitrile als Zwischenprodukte

Publications (2)

Publication Number Publication Date
CN1267305A CN1267305A (zh) 2000-09-20
CN1261442C true CN1261442C (zh) 2006-06-28

Family

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Family Applications (1)

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CNB988082616A Expired - Lifetime CN1261442C (zh) 1997-08-20 1998-08-08 用于制备草胺膦的方法以及中间体

Country Status (27)

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US (1) US6359162B1 (enExample)
EP (1) EP1005475B1 (enExample)
JP (1) JP4519316B2 (enExample)
KR (1) KR100674326B1 (enExample)
CN (1) CN1261442C (enExample)
AR (1) AR015932A1 (enExample)
AT (1) ATE258180T1 (enExample)
AU (1) AU756471B2 (enExample)
BR (1) BR9811971B1 (enExample)
CA (1) CA2301181C (enExample)
CO (1) CO5031316A1 (enExample)
CZ (1) CZ2000593A3 (enExample)
DE (2) DE19736125A1 (enExample)
DK (1) DK1005475T3 (enExample)
ES (1) ES2214727T3 (enExample)
HU (1) HUP0003501A3 (enExample)
IL (1) IL134633A0 (enExample)
MY (1) MY132853A (enExample)
PH (1) PH11998002119A1 (enExample)
PL (1) PL191587B1 (enExample)
PT (1) PT1005475E (enExample)
RU (1) RU2275376C2 (enExample)
TR (1) TR200000456T2 (enExample)
TW (1) TW530063B (enExample)
UA (1) UA66806C2 (enExample)
WO (1) WO1999009039A1 (enExample)
ZA (1) ZA987465B (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102584893A (zh) * 2012-02-07 2012-07-18 浙江工业大学 一种草铵膦的制备方法
CN107236001A (zh) * 2016-04-06 2017-10-10 四川省乐山市福华通达农药科技有限公司 一种膦醛的合成方法
CN112898338A (zh) * 2019-12-04 2021-06-04 利尔化学股份有限公司 草铵膦中间体及草铵膦的制备方法

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KR100972717B1 (ko) * 2002-03-21 2010-07-27 바이엘 쉐링 파마 악티엔게젤샤프트 혈장 카르복시펩티드분해효소 ｂ 억제제
EP2065391B1 (en) * 2006-09-20 2014-06-18 Meiji Seika Pharma Co., Ltd. Method for producing phosphorus-containing a-amino acid and production intermediate thereof
BR112012026205A2 (pt) 2010-04-14 2015-11-03 Strategic Enzyme Applic Inc processo para produção enzimática de um produto de fosfinotricina ou um precursor do mesmo
CN102372738B (zh) * 2010-08-14 2017-11-10 武汉工程大学 Lj反应在制备维蒂希试剂和草铵膦中的应用
US9255115B2 (en) 2011-09-30 2016-02-09 Meiji Seika Pharma Co. Ltd. Method for producing glufosinate P free acid
CN102372739B (zh) * 2011-12-05 2017-06-16 河北威远生化农药有限公司 一种草铵膦的合成方法
CN102399239A (zh) * 2011-12-27 2012-04-04 江苏优士化学有限公司 一种草铵膦及类似物的合成方法
CN102399240A (zh) * 2011-12-27 2012-04-04 江苏优士化学有限公司 一种改进的草铵膦及类似物的合成方法
CN103183707B (zh) * 2011-12-30 2016-06-15 中化蓝天集团有限公司 一种草胺膦的制备方法
CN103374030B (zh) * 2012-04-13 2016-03-23 浙江新安化工集团股份有限公司 一种制备草铵膦的方法及其中间体的制备方法
CN103483379A (zh) * 2013-09-26 2014-01-01 江苏辉丰农化股份有限公司 一种草铵膦酸的制备方法
MX2016014792A (es) * 2014-05-13 2017-03-23 Bayer Cropscience Ag Proceso para preparar cianhidrinas que contienen fosforo.
CN104558033B (zh) * 2014-12-19 2016-05-18 浙江工业大学 一种l-草铵膦-n-羧酸酐及其制备和应用
EA039479B1 (ru) 2015-04-27 2022-01-31 Басф Се Комбинации гербицидов, содержащие глюфосинат и индазифлам
MX2018002731A (es) 2015-09-02 2018-04-13 Bayer Cropscience Ag Proceso para la elaboracion de esteres de cianohidrina que contienen fosforo.
WO2017037034A1 (de) 2015-09-02 2017-03-09 Bayer Cropscience Aktiengesellschaft Verfahren zur herstellung von phosphorhaltigen cyanhydrinestern
CN108026122B (zh) 2015-09-02 2021-03-09 拜耳作物科学股份公司 制备含磷氰醇酯的方法
KR20180048894A (ko) 2015-09-02 2018-05-10 바이엘 크롭사이언스 악티엔게젤샤프트 인 함유 시아노하이드린 에스테르의 제조 방법
US10501485B2 (en) 2015-09-29 2019-12-10 Basf Se Process for producing phosphinates
CN107417721B (zh) * 2016-05-24 2019-05-28 四川福思达生物技术开发有限责任公司 一种氢氰酸加成工艺
WO2018108794A1 (de) 2016-12-15 2018-06-21 Bayer Cropscience Aktiengesellschaft Verfahren zur herstellung von d-glufosinat oder dessen salzen unter verwendung von ephedrin
WO2018108797A1 (de) 2016-12-15 2018-06-21 Bayer Cropscience Aktiengesellschaft Verfahren zur herstellung von l-glufosinat oder dessen salzen unter verwendung von ephedrin
EP3392237B1 (de) 2017-04-21 2019-10-02 Evonik Degussa GmbH Verfahren zur herstellung von acroleincyanhydrinen
US11634442B2 (en) * 2017-07-18 2023-04-25 Basf Se Methods for the purification of L-glufosinate
MX393530B (es) 2017-07-21 2025-03-24 Basf Se Produccion de glufosinato mediante la reaccion de acetato de 3-[n-butoxi(metil)fosforil]-1-cianopropilo para obtener una mezcla de n-butil (3-amino-3-cianopropil)metilfosfinato y sales de amonio de acido (3-amino-3-cianopropil)metilfosfinico.
EP3728278B1 (de) 2017-12-19 2022-11-30 Basf Se Verfahren zur herstellung von phosphorhaltigen aminonitrilen und glufosinat
CN109134534B (zh) * 2018-08-08 2020-09-08 江苏好收成韦恩农化股份有限公司 一种3,3-二烷氧基丙基甲基膦酸酯简易制备方法
KR102131687B1 (ko) * 2018-09-10 2020-07-08 주식회사 휴런 파킨슨 병 진단 장치 및 방법
BR112021013261B1 (pt) 2019-01-11 2024-02-20 Cj Cheiljedang Corporation Método para produzir l-glufosinato
CN111662324B (zh) * 2019-03-05 2023-02-24 利尔化学股份有限公司 一种制备l-草铵膦的方法
CN111662325B (zh) * 2019-03-05 2023-03-24 利尔化学股份有限公司 一种制备l-草铵膦的方法
CN111662326B (zh) * 2019-03-05 2023-03-24 利尔化学股份有限公司 一种制备l-草铵膦的方法
CN110003269B (zh) * 2019-04-29 2022-04-05 利尔化学股份有限公司 低能耗生产草铵膦的方法
CN110590836B (zh) * 2019-09-30 2022-07-26 江苏七洲绿色化工股份有限公司 一种草铵膦中间体的合成方法
CN111659330B (zh) * 2020-04-23 2021-05-07 河北威远生物化工有限公司 一种连续化生产草铵膦的工艺与设备
CN112358499A (zh) * 2020-11-12 2021-02-12 江苏春江润田农化有限公司 一种草铵膦的合成方法
JP7728880B2 (ja) 2021-04-01 2025-08-25 エボニック オペレーションズ ゲーエムベーハー Ｌ－グルホシネートおよびそのホスホエステルを産生するための酵素的方法
EP4105335A1 (en) 2021-06-16 2022-12-21 Evonik Operations GmbH Enzymatic method for the production of l-glufosinate p-alkyl esters
EP4219512B1 (en) * 2021-07-20 2024-08-28 Lier Chemical Co., Ltd. Method for preparing glufosinate or analog thereof
EP4151643A1 (en) 2021-09-16 2023-03-22 Evonik Operations GmbH Improved process for production of phosphoesters of glufosinate precursors
CN114163472B (zh) * 2021-11-27 2024-08-09 永农生物科学有限公司 醇溶剂下合成α-氨基腈的方法及草铵膦的合成方法
EP4493709A1 (en) 2022-03-14 2025-01-22 Evonik Operations GmbH Enzymatic method for the production of l-glufosinate p-esters
CN116041387B (zh) * 2022-11-17 2023-07-14 永农生物科学有限公司 一种草铵膦的制备方法
KR20250152064A (ko) 2023-02-23 2025-10-22 바스프 에스이 시안히드린 또는 시안히드린 유도체로부터 l-글루포시네이트의 제조 방법
CN121335908A (zh) 2023-06-13 2026-01-13 巴斯夫欧洲公司 使用基于酰胺酶的工艺的草铵膦合成

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DE2849003A1 (de) 1978-11-11 1980-08-21 Hoechst Ag Phosphorhaltige cyanhydrinderivate und verfahren zu ihrer herstellung
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102584893A (zh) * 2012-02-07 2012-07-18 浙江工业大学 一种草铵膦的制备方法
CN102584893B (zh) * 2012-02-07 2015-03-04 浙江工业大学 一种草铵膦的制备方法
CN107236001A (zh) * 2016-04-06 2017-10-10 四川省乐山市福华通达农药科技有限公司 一种膦醛的合成方法
CN112898338A (zh) * 2019-12-04 2021-06-04 利尔化学股份有限公司 草铵膦中间体及草铵膦的制备方法

Also Published As

Publication number Publication date
TR200000456T2 (tr) 2000-07-21
DE59810636D1 (de) 2004-02-26
AU756471B2 (en) 2003-01-16
RU2275376C2 (ru) 2006-04-27
US6359162B1 (en) 2002-03-19
TW530063B (en) 2003-05-01
IL134633A0 (en) 2001-04-30
CN1267305A (zh) 2000-09-20
UA66806C2 (uk) 2004-06-15
JP4519316B2 (ja) 2010-08-04
ZA987465B (en) 1999-02-22
HUP0003501A3 (en) 2002-01-28
PH11998002119A1 (en) 2003-10-10
HUP0003501A2 (en) 2001-03-28
AU9259898A (en) 1999-03-08
KR100674326B1 (ko) 2007-01-24
WO1999009039A1 (de) 1999-02-25
JP2001515084A (ja) 2001-09-18
DE19736125A1 (de) 1999-02-25
CO5031316A1 (es) 2001-04-27
KR20010023069A (ko) 2001-03-26
DK1005475T3 (da) 2004-05-17
CZ2000593A3 (cs) 2000-06-14
ATE258180T1 (de) 2004-02-15
PL338855A1 (en) 2000-11-20
PL191587B1 (pl) 2006-06-30
CA2301181A1 (en) 1999-02-25
ES2214727T3 (es) 2004-09-16
BR9811971A (pt) 2000-08-15
EP1005475A1 (de) 2000-06-07
EP1005475B1 (de) 2004-01-21
BR9811971B1 (pt) 2010-12-28
CA2301181C (en) 2008-08-05
AR015932A1 (es) 2001-05-30
MY132853A (en) 2007-10-31
PT1005475E (pt) 2004-06-30

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