CN1233962A - 基本无萜烯的银杏类黄酮提取物在牙颊领域中的应用以及含有这种提取物的组合物 - Google Patents
基本无萜烯的银杏类黄酮提取物在牙颊领域中的应用以及含有这种提取物的组合物 Download PDFInfo
- Publication number
- CN1233962A CN1233962A CN97199102A CN97199102A CN1233962A CN 1233962 A CN1233962 A CN 1233962A CN 97199102 A CN97199102 A CN 97199102A CN 97199102 A CN97199102 A CN 97199102A CN 1233962 A CN1233962 A CN 1233962A
- Authority
- CN
- China
- Prior art keywords
- extract
- purposes
- compositions
- terpenic
- folium ginkgo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9771—Ginkgophyta, e.g. Ginkgoaceae [Ginkgo family]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Birds (AREA)
- Alternative & Traditional Medicine (AREA)
- Medical Informatics (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
上层真皮 | 中层真皮 | 下层真皮 | |
HLE单用HLE+PMSF | 0 | 0 | 0 |
25 | 55 | 70 | |
银杏提取物+神经酰胺(10%) (10%)0 0.10 0.20.1 00.3 00.5 00.1 0.10.3 0.10.5 0.10.1 0.20.3 0.20.5 0.2 | 00002.50056.70070 | 000031.85017.64701953.2 | 27.6522.5013.853361.2024.5236515.23080 |
第0天 | 第28天 | |
齿龈炎的评估 | 3.50±1 | 1.0±1.2(p<0.05) |
牙龈颜色的评估(红斑) | 4.00±1.4 | 1.1±1.45(p<0.05) |
牙龈红斑的形状 | 4.80±1.7 | 1.6±11.8(p<0.05) |
乳突出血的评估 | 0.85±0.8 | 0.1±0.43(p<0.05) |
乳突出血的形状 | 1.20±1.12 | 0.1±0.43(p<0.05) |
自发性疼痛的评估 | 1.35±1.2 | 0(p<0.05) |
咀嚼性疼痛的评估 | 1.10±1.17 | 0(p<0.05) |
总分 | 16.80±4.8 | 3.9±4.6(p<0.05) |
Claims (21)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9613065A FR2755015B1 (fr) | 1996-10-25 | 1996-10-25 | Utilisation d'un extrait flavonoidique de ginkgo biloba substantiellement depourvu de terpenes, dans le domaine buccodentaire, et composition contenant un tel extrait |
FR96/13065 | 1996-10-25 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1233962A true CN1233962A (zh) | 1999-11-03 |
CN100335062C CN100335062C (zh) | 2007-09-05 |
Family
ID=9497047
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB971991022A Expired - Fee Related CN100335062C (zh) | 1996-10-25 | 1997-10-24 | 基本无萜烯的银杏类黄酮提取物在制备治疗牙颊区域炎症的药物中的应用以及含有这种提取物的组合物 |
Country Status (17)
Country | Link |
---|---|
US (4) | US6159450A (zh) |
EP (2) | EP1393736A1 (zh) |
JP (1) | JP4598900B2 (zh) |
CN (1) | CN100335062C (zh) |
AR (1) | AR008506A1 (zh) |
AT (1) | ATE257710T1 (zh) |
AU (1) | AU4951297A (zh) |
CA (1) | CA2269895C (zh) |
DE (1) | DE69727239T2 (zh) |
DK (1) | DK0934074T3 (zh) |
ES (1) | ES2213820T3 (zh) |
FR (1) | FR2755015B1 (zh) |
HK (1) | HK1024165A1 (zh) |
MY (1) | MY120958A (zh) |
NO (1) | NO991943L (zh) |
TW (1) | TW436289B (zh) |
WO (1) | WO1998018479A1 (zh) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2755015B1 (fr) * | 1996-10-25 | 1998-12-24 | Sod Conseils Rech Applic | Utilisation d'un extrait flavonoidique de ginkgo biloba substantiellement depourvu de terpenes, dans le domaine buccodentaire, et composition contenant un tel extrait |
DK1163908T3 (da) | 2000-06-16 | 2004-07-12 | Linnea Sa | Vandoplöseligt kompleks af et ekstrakt af Ginkgo biloba, fremgangsmåde til fremstilling heraf og sammensætning, der indeholder komplekset |
CA2431044A1 (en) * | 2000-12-13 | 2002-06-20 | University Of Rochester | Oral compositions and use thereof |
US20040101578A1 (en) * | 2001-08-03 | 2004-05-27 | Min-Young Kim | Compositon containg ginkgo biloba that inhibit angiogenesis and matrix metalloprotinase |
US20040057908A1 (en) * | 2001-12-13 | 2004-03-25 | Bowen William H. | Oral compositions and use thereof |
DE10308162A1 (de) * | 2003-02-26 | 2004-09-09 | Universitätsklinikum Freiburg | Verfahren zur Herstellung von Flavonoid-haltigen Zusammensetzungen und ihre Verwendung |
GB0304726D0 (en) * | 2003-03-01 | 2003-04-02 | Ardana Bioscience Ltd | New Process |
JP5294536B2 (ja) * | 2005-03-31 | 2013-09-18 | 小林製薬株式会社 | 歯肉上皮細胞伸展阻害剤 |
EP2459205A1 (en) * | 2009-07-28 | 2012-06-06 | Velleja Research SRL | Ginkgo biloba extract with a standardised ginkgo flavone glycosides content deprived of the paf-antagonist terpenic fraction, and compositions containing it, for the prevention and treatment of circulatory, cognitive, geriatric and sensory disorders |
JP2011225550A (ja) * | 2010-03-30 | 2011-11-10 | Cci Corp | マトリックスメタロプロテアーゼ産生抑制及びエラスターゼ活性阻害剤 |
CN104225109A (zh) * | 2014-10-14 | 2014-12-24 | 张德信 | 治疗胃火牙痛的中药制剂及制法 |
DE102014222915A1 (de) * | 2014-11-11 | 2016-05-12 | Henkel Ag & Co. Kgaa | Mund- und Zahnpflege- und -reinigungsmittel mit Ginkgo Biloba zur Zahnfleischvitalisierung |
JP2021532079A (ja) * | 2018-07-12 | 2021-11-25 | オキュソフト インコーポレイテッドOCuSOFT, Inc. | 目の抗アレルギ用組成物および眼瞼洗浄ワイプ |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5683416A (en) * | 1979-12-11 | 1981-07-08 | Lion Corp | Composition for oral cavity |
JPS5791932A (en) * | 1980-11-28 | 1982-06-08 | Kuraray Co Ltd | Polyprenyl compound |
JPS58213706A (ja) * | 1982-06-08 | 1983-12-12 | Lion Corp | 歯垢形成抑制用剤 |
CH678150A5 (zh) * | 1987-12-18 | 1991-08-15 | Nuova Linnea S A | |
GB8822004D0 (en) * | 1988-09-20 | 1988-10-19 | Indena Spa | New extracts of ginkgo biloba & their methods of preparation |
US5637302A (en) * | 1988-09-20 | 1997-06-10 | Indena Spa | Extracts of Ginkgo biloba and their methods of preparation |
FR2640621B1 (fr) * | 1988-12-19 | 1992-10-30 | Centre Nat Rech Scient | N-aryl-azetidinones, leur procede de preparation et leur utilisation comme inhibiteurs des elastases |
ATE118550T1 (de) * | 1989-03-08 | 1995-03-15 | Hayashibara Biochem Lab | Herstellung und verwendungen von alpha- glycosylrutin. |
NL8900943A (nl) * | 1989-04-14 | 1990-11-01 | Euro Biopharm Technology B V | Protease inhibitor. |
KR940002795B1 (ko) * | 1989-06-16 | 1994-04-02 | 주식회사 선경인더스트리 | 은행잎에서 징코라이드를 분리 및 정제하는 방법 |
DE3940094A1 (de) * | 1989-12-04 | 1991-06-06 | Montana Ltd | Wirkstoffkonzentrate und neue wirkstoff-kombinationen aus blaettern von ginkgo biloba, ein verfahren zu ihrer herstellung und die wirkstoff-konzentrate bzw. die wirkstoff-kombinationen enthaltenden arzneimittel |
DE3940091A1 (de) * | 1989-12-04 | 1991-06-06 | Schwabe Willmar Gmbh & Co | Extrakt aus blaettern von ginkgo biloba, verfahren zu seiner herstellung und den extrakt enthaltende arzneimittel |
DE3940092A1 (de) * | 1989-12-04 | 1991-06-06 | Schwabe Willmar Gmbh & Co | Extrakt aus blaettern von ginkgo biloba, verfahren zu seiner herstellung und den extrakt enthaltende arzneimittel |
US5214191A (en) * | 1990-05-22 | 1993-05-25 | Cortech, Inc. | Oxidant sensitive and insensitive aromatic esters as inhibitors of human neutrophil elastase |
JPH0463545A (ja) * | 1990-06-30 | 1992-02-28 | Nippon Green Ueebu Kk | チューインガム |
IT1245371B (it) * | 1991-03-28 | 1994-09-20 | Geymonat Spa | Derivati di flavoni, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono |
US5578307A (en) * | 1992-01-17 | 1996-11-26 | Alfatec-Pharma Gmbh | Shaped articles containing plant extract(s), in particular pellets, and their pharmaceutical or cosmetic use |
EP0577143B1 (de) * | 1992-07-03 | 1999-01-27 | ALFATEC-PHARMA GmbH | Feste und flüssige Lösungen von Flavonoiden |
JPH06183940A (ja) * | 1992-12-21 | 1994-07-05 | Lion Corp | 口腔用組成物 |
FR2699818B1 (fr) * | 1992-12-24 | 1995-02-03 | Oreal | Composition cosmétique ou pharmaceutique contenant en association un polyphénol et un extrait de gingko. |
DE4334600C2 (de) * | 1993-10-11 | 1997-07-03 | Hgb Pharma Service Gmbh | Topische Formulierung eines solubilisierten Ginkgo-biloba-Extraktes |
JP3518882B2 (ja) * | 1993-11-12 | 2004-04-12 | ダイセル化学工業株式会社 | イチョウエキス及びその製造法 |
JPH07165551A (ja) * | 1993-12-14 | 1995-06-27 | Lion Corp | 口腔用組成物 |
FR2715582B1 (fr) * | 1994-02-02 | 1996-03-15 | Centre Nat Rech Scient | Microcapsules à paroi de flavonoïde réticulée et compositions en contenant. |
JP3012911U (ja) * | 1994-12-22 | 1995-06-27 | 竹野 芳廣 | 身体の清浄用具 |
GB9508533D0 (en) * | 1995-04-27 | 1995-06-14 | Sod Conseils Rech Applic | Flavonoid extract of ginkgo biloba as flavouring and/or texturing agent |
MX9710258A (es) * | 1995-06-23 | 1998-08-30 | Medichem Res Inc | Biflavanoides y derivados de los mismos como agentes antivirales. |
JPH0942556A (ja) * | 1995-08-02 | 1997-02-14 | Nippon Kokan Pipe Fittings Mfg Co Ltd | 伸縮継手 |
FR2755015B1 (fr) * | 1996-10-25 | 1998-12-24 | Sod Conseils Rech Applic | Utilisation d'un extrait flavonoidique de ginkgo biloba substantiellement depourvu de terpenes, dans le domaine buccodentaire, et composition contenant un tel extrait |
US6030621A (en) * | 1998-03-19 | 2000-02-29 | De Long; Xie | Ginkgo biloba composition, method to prepare the same and uses thereof |
-
1996
- 1996-10-25 FR FR9613065A patent/FR2755015B1/fr not_active Expired - Fee Related
-
1997
- 1997-10-24 WO PCT/FR1997/001910 patent/WO1998018479A1/fr active IP Right Grant
- 1997-10-24 MY MYPI97005041A patent/MY120958A/en unknown
- 1997-10-24 DK DK97912251T patent/DK0934074T3/da active
- 1997-10-24 DE DE69727239T patent/DE69727239T2/de not_active Expired - Lifetime
- 1997-10-24 CN CNB971991022A patent/CN100335062C/zh not_active Expired - Fee Related
- 1997-10-24 AT AT97912251T patent/ATE257710T1/de active
- 1997-10-24 AR ARP970104933A patent/AR008506A1/es active IP Right Grant
- 1997-10-24 EP EP03078241A patent/EP1393736A1/fr not_active Withdrawn
- 1997-10-24 CA CA2269895A patent/CA2269895C/fr not_active Expired - Fee Related
- 1997-10-24 JP JP52011098A patent/JP4598900B2/ja not_active Expired - Fee Related
- 1997-10-24 ES ES97912251T patent/ES2213820T3/es not_active Expired - Lifetime
- 1997-10-24 EP EP97912251A patent/EP0934074B1/fr not_active Expired - Lifetime
- 1997-10-24 US US09/284,125 patent/US6159450A/en not_active Expired - Lifetime
- 1997-10-24 AU AU49512/97A patent/AU4951297A/en not_active Abandoned
- 1997-10-30 TW TW086115900A patent/TW436289B/zh not_active IP Right Cessation
-
1999
- 1999-04-23 NO NO991943A patent/NO991943L/no not_active Application Discontinuation
-
2000
- 2000-05-02 HK HK00102629A patent/HK1024165A1/xx not_active IP Right Cessation
- 2000-06-23 US US09/603,447 patent/US6340456B1/en not_active Expired - Fee Related
-
2001
- 2001-11-26 US US09/994,351 patent/US6488923B2/en not_active Expired - Fee Related
-
2002
- 2002-09-17 US US10/245,541 patent/US6818208B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
HK1024165A1 (en) | 2000-10-05 |
DK0934074T3 (da) | 2004-05-17 |
US20030044476A1 (en) | 2003-03-06 |
CA2269895C (fr) | 2011-01-18 |
JP4598900B2 (ja) | 2010-12-15 |
FR2755015A1 (fr) | 1998-04-30 |
NO991943L (no) | 1999-06-23 |
JP2001503405A (ja) | 2001-03-13 |
DE69727239D1 (de) | 2004-02-19 |
ES2213820T3 (es) | 2004-09-01 |
AU4951297A (en) | 1998-05-22 |
EP1393736A1 (fr) | 2004-03-03 |
US6159450A (en) | 2000-12-12 |
EP0934074A1 (fr) | 1999-08-11 |
WO1998018479A1 (fr) | 1998-05-07 |
US6818208B2 (en) | 2004-11-16 |
EP0934074B1 (fr) | 2004-01-14 |
AR008506A1 (es) | 2000-01-19 |
FR2755015B1 (fr) | 1998-12-24 |
US6488923B2 (en) | 2002-12-03 |
NO991943D0 (no) | 1999-04-23 |
ATE257710T1 (de) | 2004-01-15 |
DE69727239T2 (de) | 2004-11-04 |
CN100335062C (zh) | 2007-09-05 |
US6340456B1 (en) | 2002-01-22 |
US20020064571A1 (en) | 2002-05-30 |
MY120958A (en) | 2005-12-30 |
CA2269895A1 (fr) | 1998-05-07 |
TW436289B (en) | 2001-05-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP2155222B1 (en) | Extract of trigonella foenum-graecum | |
EP0660698B1 (fr) | Composition cosmetique ou dermatologique contenant au moins une saponine de type ginsenoside, et ses applications, notamment pour le soin des cheveux | |
CN100335062C (zh) | 基本无萜烯的银杏类黄酮提取物在制备治疗牙颊区域炎症的药物中的应用以及含有这种提取物的组合物 | |
IE58282B1 (en) | Composition reducing sebum spreading | |
JPH11508910A (ja) | 脱色素効果のあるスキンケア用化粧品組成物およびその使用 | |
KR0128057B1 (ko) | 피부 미소순환에 작용하는 약리적 조성물 | |
CA2139253C (en) | Skin external agent | |
EP1890769A1 (en) | Hair tonic | |
JP2000191542A (ja) | 骨粗鬆症予防、治療剤 | |
KR20100124132A (ko) | 효소처리를 이용한 혼합생약재 추출물을 함유하는 피부 주름개선용 화장료 조성물 및 그 추출방법 | |
WO1996007393A1 (fr) | Activateur de cellule mere de cheveux et procede d'activation de cellule mere de cheveux | |
DE60125955T2 (de) | Bioaktive fraktion von eurycoma longifolia | |
JP3998085B2 (ja) | ヒアルロン酸量増加促進剤 | |
KR980008209A (ko) | 치약 조성물 | |
CN113143788A (zh) | 一种具有保湿修复舒缓的多效组合物及面霜 | |
EP1620116B1 (fr) | Utilisation du quinquina pour la preparation d'un medicament stimulant l'angiogenese | |
JP2731329B2 (ja) | 皮膚化粧料 | |
KR20090059230A (ko) | 탈모예방, 항염작용, 모근세포 활성화 및 모발생장을촉진하는 화장료 조성물 | |
FR2858227A1 (fr) | Utilisation cosmetique d'un derive de biguanide en tant qu'actif anti-vieillissement de la peau | |
JPS62263110A (ja) | 被膚老化予防化粧料 | |
KR0173407B1 (ko) | 당삼의 알코올 추출물을 함유하는 육모제 조성물 | |
JP3154285B2 (ja) | コラゲナーゼ活性阻害剤 | |
SU1395328A1 (ru) | Способ лечени диффузного нейродермита | |
WO1994005301A1 (en) | Dermatitis treatment compositions containing sulphur, salicylic acid and dimethylsulphone | |
HU209867B (en) | Cosmetic composition and process for making medicative composition |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
REG | Reference to a national code |
Ref country code: HK Ref legal event code: GR Ref document number: 1024165 Country of ref document: HK |
|
C56 | Change in the name or address of the patentee |
Owner name: IPSEN MEDICINE CO.,LTD. Free format text: FORMER NAME: SOCIETE DE CONSEILS DE RECHERCHES ET D APPLICATIONS SCIENTIFIQUES S.A. |
|
CP03 | Change of name, title or address |
Address after: France Patentee after: Ipsen Pharma Address before: France Patentee before: SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) |
|
C56 | Change in the name or address of the patentee | ||
CP03 | Change of name, title or address |
Address after: France - Georges Plantagenet of Boulogne Billancourt pier No. 65 Patentee after: Ipsen Pharma Address before: France Patentee before: Ipsen Pharma |
|
C17 | Cessation of patent right | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20070905 Termination date: 20131024 |