CN1177847C - 作为5－ht2a拮抗剂的噁唑烷酮类化合物 - Google Patents
作为5－ht2a拮抗剂的噁唑烷酮类化合物 Download PDFInfo
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- CN1177847C CN1177847C CNB988028344A CN98802834A CN1177847C CN 1177847 C CN1177847 C CN 1177847C CN B988028344 A CNB988028344 A CN B988028344A CN 98802834 A CN98802834 A CN 98802834A CN 1177847 C CN1177847 C CN 1177847C
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- compound
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- ketone
- oxazolidine
- phenyl
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- A61P25/00—Drugs for disorders of the nervous system
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Nutrition Science (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Anesthesiology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Child & Adolescent Psychology (AREA)
- Vascular Medicine (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19707628.9 | 1997-02-26 | ||
| DE19707628A DE19707628A1 (de) | 1997-02-26 | 1997-02-26 | Oxazolidinone |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1248973A CN1248973A (zh) | 2000-03-29 |
| CN1177847C true CN1177847C (zh) | 2004-12-01 |
Family
ID=7821498
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB988028344A Expired - Fee Related CN1177847C (zh) | 1997-02-26 | 1998-02-06 | 作为5－ht2a拮抗剂的噁唑烷酮类化合物 |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US6462056B1 (enExample) |
| EP (1) | EP0964863B1 (enExample) |
| JP (2) | JP4402175B2 (enExample) |
| KR (1) | KR20000075697A (enExample) |
| CN (1) | CN1177847C (enExample) |
| AR (1) | AR010899A1 (enExample) |
| AT (1) | ATE240954T1 (enExample) |
| AU (1) | AU739251B2 (enExample) |
| BR (1) | BR9807765A (enExample) |
| CA (1) | CA2281918C (enExample) |
| CZ (1) | CZ299199A3 (enExample) |
| DE (2) | DE19707628A1 (enExample) |
| DK (1) | DK0964863T3 (enExample) |
| ES (1) | ES2197466T3 (enExample) |
| HU (1) | HUP0001093A3 (enExample) |
| ID (1) | ID22838A (enExample) |
| NO (1) | NO313415B1 (enExample) |
| PL (1) | PL335100A1 (enExample) |
| PT (1) | PT964863E (enExample) |
| RU (1) | RU2196140C2 (enExample) |
| SK (1) | SK112799A3 (enExample) |
| TW (1) | TW531538B (enExample) |
| UA (1) | UA58542C2 (enExample) |
| WO (1) | WO1998038189A1 (enExample) |
| ZA (1) | ZA981579B (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2787328A1 (fr) | 1998-12-22 | 2000-06-23 | Sanofi Sa | Utilisation d'un antagoniste des recepteurs 5ht2a pour la preparation de medicaments utiles dans le traitement des ronflements et du syndrome de haute resistance ou de resistance des voies aeriennes superieures |
| WO2000044376A1 (en) * | 1999-01-28 | 2000-08-03 | Bristol-Myers Squibb Company | Antidepressant heterocyclic compounds |
| ES2165274B1 (es) | 1999-06-04 | 2003-04-01 | Almirall Prodesfarma Sa | Nuevos derivados de indolilpiperidina como agentes antihistaminicos y antialergicos. |
| KR20010085555A (ko) | 1999-06-24 | 2001-09-07 | 히라이 가쯔히꼬 | 아드레날린 알파1비 수용체 길항약 |
| GB9928568D0 (en) * | 1999-12-03 | 2000-02-02 | Zeneca Ltd | Chemical compounds |
| GB0009803D0 (en) * | 2000-04-25 | 2000-06-07 | Astrazeneca Ab | Chemical compounds |
| ES2172436B1 (es) | 2000-10-31 | 2004-01-16 | Almirall Prodesfarma Sa | Derivados de indolilpiperidina como agentes antihistaminicos y antialergicos. |
| WO2002081470A1 (en) * | 2001-04-07 | 2002-10-17 | Astrazeneca Ab | Oxazolidinones containing a sulfonimid group as antibiotics |
| MXPA04007067A (es) * | 2002-01-22 | 2004-11-01 | Upjohn Co | Dispositivos medicos resistentes a infecciones. |
| WO2004069828A1 (ja) * | 2003-02-04 | 2004-08-19 | Mitsubishi Pharma Corporation | ピペリジン化合物およびその医薬用途 |
| EP2343073A3 (en) | 2003-12-11 | 2011-10-12 | Sepracor Inc. | Combination of a sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression |
| US7157584B2 (en) * | 2004-02-25 | 2007-01-02 | Takeda Pharmaceutical Company Limited | Benzimidazole derivative and use thereof |
| CL2008001002A1 (es) * | 2007-04-11 | 2008-10-17 | Actelion Pharmaceuticals Ltd | Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana. |
| CN101903380B (zh) * | 2007-12-18 | 2013-04-17 | 埃科特莱茵药品有限公司 | 5-氨基环甲基-噁唑啶-2-酮衍生物 |
| WO2010041218A2 (en) * | 2008-10-10 | 2010-04-15 | Actelion Pharmaceuticals Ltd | Oxazolidinyl antibiotics |
| WO2014046544A1 (en) | 2012-09-21 | 2014-03-27 | Aapa B.V. | Substituted 3-heteroaryloxy-3-(hetero)aryl-propylamines as serotonin transporter and serotonin ht2c receptor modulators |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3723797A1 (de) * | 1987-07-18 | 1989-01-26 | Merck Patent Gmbh | Oxazolidinone |
| DE4005371A1 (de) * | 1990-02-21 | 1991-08-22 | Merck Patent Gmbh | Oxazolidinone |
| DE4017211A1 (de) * | 1990-05-29 | 1991-12-05 | Merck Patent Gmbh | Oxazolidinone |
| DK152090D0 (da) * | 1990-06-22 | 1990-06-22 | Lundbaek A S H | Piperidylsubstituerede indolderivater |
| DK158590D0 (da) * | 1990-07-02 | 1990-07-02 | Lundbeck & Co As H | Indolderivater |
| ATE170516T1 (de) * | 1992-07-14 | 1998-09-15 | Nippon Chemiphar Co | Alkylendiaminderivate |
| DE4324393A1 (de) * | 1993-07-21 | 1995-01-26 | Merck Patent Gmbh | 4-Aryloxy- und 4-Arylthiopiperidinderivate |
| DE4414113A1 (de) * | 1994-04-22 | 1995-10-26 | Merck Patent Gmbh | 3-Indolylpiperidine |
| ZA954689B (en) * | 1994-06-08 | 1996-01-29 | Lundbeck & Co As H | 4-Aryl-1-(indanmethyl dihydrobenzofuranmethyl or dihydrobenzothiophenemethyl) piperidines tetrahydropyridines or piperazines |
| DE19500689A1 (de) * | 1995-01-12 | 1996-07-18 | Merck Patent Gmbh | Indolpiperidin-Derivate |
-
1997
- 1997-02-26 DE DE19707628A patent/DE19707628A1/de not_active Withdrawn
-
1998
- 1998-02-06 DK DK98909397T patent/DK0964863T3/da active
- 1998-02-06 ES ES98909397T patent/ES2197466T3/es not_active Expired - Lifetime
- 1998-02-06 US US09/380,202 patent/US6462056B1/en not_active Expired - Fee Related
- 1998-02-06 BR BR9807765-1A patent/BR9807765A/pt not_active IP Right Cessation
- 1998-02-06 CA CA002281918A patent/CA2281918C/en not_active Expired - Fee Related
- 1998-02-06 PT PT98909397T patent/PT964863E/pt unknown
- 1998-02-06 SK SK1127-99A patent/SK112799A3/sk unknown
- 1998-02-06 AT AT98909397T patent/ATE240954T1/de not_active IP Right Cessation
- 1998-02-06 WO PCT/EP1998/000637 patent/WO1998038189A1/de not_active Ceased
- 1998-02-06 HU HU0001093A patent/HUP0001093A3/hu unknown
- 1998-02-06 KR KR1019997007764A patent/KR20000075697A/ko not_active Ceased
- 1998-02-06 RU RU99120183/04A patent/RU2196140C2/ru not_active IP Right Cessation
- 1998-02-06 PL PL98335100A patent/PL335100A1/xx unknown
- 1998-02-06 CZ CZ992991A patent/CZ299199A3/cs unknown
- 1998-02-06 DE DE59808461T patent/DE59808461D1/de not_active Expired - Lifetime
- 1998-02-06 EP EP98909397A patent/EP0964863B1/de not_active Expired - Lifetime
- 1998-02-06 AU AU63949/98A patent/AU739251B2/en not_active Ceased
- 1998-02-06 CN CNB988028344A patent/CN1177847C/zh not_active Expired - Fee Related
- 1998-02-06 JP JP53722398A patent/JP4402175B2/ja not_active Expired - Fee Related
- 1998-02-06 ID IDW990813D patent/ID22838A/id unknown
- 1998-02-23 TW TW087102539A patent/TW531538B/zh not_active IP Right Cessation
- 1998-02-25 ZA ZA981579A patent/ZA981579B/xx unknown
- 1998-02-26 AR ARP980100858A patent/AR010899A1/es not_active Application Discontinuation
- 1998-06-02 UA UA99095309A patent/UA58542C2/uk unknown
-
1999
- 1999-08-25 NO NO19994106A patent/NO313415B1/no not_active IP Right Cessation
-
2009
- 2009-06-24 JP JP2009149274A patent/JP2009256363A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2281918A1 (en) | 1998-09-03 |
| PL335100A1 (en) | 2000-04-10 |
| EP0964863A1 (de) | 1999-12-22 |
| ZA981579B (en) | 1999-03-17 |
| HUP0001093A3 (en) | 2001-07-30 |
| SK112799A3 (en) | 2000-06-12 |
| AR010899A1 (es) | 2000-07-12 |
| CN1248973A (zh) | 2000-03-29 |
| CA2281918C (en) | 2007-04-03 |
| JP4402175B2 (ja) | 2010-01-20 |
| ES2197466T3 (es) | 2004-01-01 |
| AU739251B2 (en) | 2001-10-04 |
| DE59808461D1 (de) | 2003-06-26 |
| TW531538B (en) | 2003-05-11 |
| ID22838A (id) | 1999-12-09 |
| PT964863E (pt) | 2003-10-31 |
| BR9807765A (pt) | 2000-02-22 |
| WO1998038189A1 (de) | 1998-09-03 |
| HUP0001093A2 (hu) | 2001-06-28 |
| CZ299199A3 (cs) | 1999-11-17 |
| EP0964863B1 (de) | 2003-05-21 |
| KR20000075697A (ko) | 2000-12-26 |
| UA58542C2 (uk) | 2003-08-15 |
| DK0964863T3 (da) | 2003-08-04 |
| DE19707628A1 (de) | 1998-08-27 |
| JP2001513764A (ja) | 2001-09-04 |
| JP2009256363A (ja) | 2009-11-05 |
| NO994106D0 (no) | 1999-08-25 |
| ATE240954T1 (de) | 2003-06-15 |
| NO994106L (no) | 1999-10-19 |
| NO313415B1 (no) | 2002-09-30 |
| RU2196140C2 (ru) | 2003-01-10 |
| AU6394998A (en) | 1998-09-18 |
| US6462056B1 (en) | 2002-10-08 |
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