CN116676305A - 使用化学修饰的引导rna的高特异性基因组编辑 - Google Patents

使用化学修饰的引导rna的高特异性基因组编辑 Download PDF

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CN116676305A
CN116676305A CN202310155019.2A CN202310155019A CN116676305A CN 116676305 A CN116676305 A CN 116676305A CN 202310155019 A CN202310155019 A CN 202310155019A CN 116676305 A CN116676305 A CN 116676305A
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certain embodiments
sequence
target
guide
modification
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D·J·德林杰
D·E·赖安
S·罗伊
J·R·桑普森
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Agilent Technologies Inc
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Agilent Technologies Inc
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CN202310155019.2A 2016-06-08 2017-06-08 使用化学修饰的引导rna的高特异性基因组编辑 Pending CN116676305A (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201662347553P 2016-06-08 2016-06-08
US62/347,553 2016-06-08
US15/493,129 2017-04-20
US15/493,129 US10767175B2 (en) 2016-06-08 2017-04-20 High specificity genome editing using chemically modified guide RNAs
PCT/US2017/036648 WO2017214460A1 (en) 2016-06-08 2017-06-08 High specificity genome editing using chemically modified guide rnas
CN201780049055.3A CN109563514B (zh) 2016-06-08 2017-06-08 使用化学修饰的引导rna的高特异性基因组编辑

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US (2) US10767175B2 (enExample)
EP (1) EP3469084A4 (enExample)
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CN (2) CN116676305A (enExample)
AU (1) AU2017277918B2 (enExample)
CA (1) CA3026372A1 (enExample)
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