CN1158387C - 编码l.infantum的四种蛋白质的抗原决定簇的嵌合基因 - Google Patents

编码l.infantum的四种蛋白质的抗原决定簇的嵌合基因 Download PDF

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Publication number
CN1158387C
CN1158387C CNB998163066A CN99816306A CN1158387C CN 1158387 C CN1158387 C CN 1158387C CN B998163066 A CNB998163066 A CN B998163066A CN 99816306 A CN99816306 A CN 99816306A CN 1158387 C CN1158387 C CN 1158387C
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protein
ala
leishmaniasis
gly
ser
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Chinese (zh)
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CN1335889A (zh
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卡洛斯·贝达特·阿隆索
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CBF Leti SA
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CBF Leti SA
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CNB998163066A 1998-12-23 1999-12-23 编码l.infantum的四种蛋白质的抗原决定簇的嵌合基因 Expired - Lifetime CN1158387C (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US11382598P 1998-12-23 1998-12-23
US60/113,825 1998-12-23
CA2,256,124 1998-12-23
CA2256124A CA2256124C (en) 1998-12-23 1998-12-23 Chimeric gene formed of the dna sequences that encode the antigenic determinants of four proteins of l. infantum, and protein encoded by said gene, and pharmaceutical composition useful for preventing and/or treating leishmaniosis in animals or humans

Publications (2)

Publication Number Publication Date
CN1335889A CN1335889A (zh) 2002-02-13
CN1158387C true CN1158387C (zh) 2004-07-21

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ID=25680668

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB998163066A Expired - Lifetime CN1158387C (zh) 1998-12-23 1999-12-23 编码l.infantum的四种蛋白质的抗原决定簇的嵌合基因

Country Status (22)

Country Link
EP (1) EP1141305B1 (enExample)
CN (1) CN1158387C (enExample)
AT (2) ATE429498T1 (enExample)
AU (1) AU759316B2 (enExample)
BE (1) BE2016C049I2 (enExample)
BG (1) BG65569B1 (enExample)
BR (1) BRPI9916549B8 (enExample)
CY (3) CY1105331T1 (enExample)
CZ (1) CZ20012360A3 (enExample)
DE (2) DE69940793D1 (enExample)
DK (1) DK1141305T3 (enExample)
ES (2) ES2326174T3 (enExample)
HR (1) HRP20010554A2 (enExample)
HU (1) HUP0104743A3 (enExample)
IL (2) IL143956A0 (enExample)
LU (1) LU93259I2 (enExample)
MX (1) MXPA01006548A (enExample)
NL (1) NL300830I2 (enExample)
PT (2) PT1624063E (enExample)
SI (1) SI1624063T1 (enExample)
TR (1) TR200102655T2 (enExample)
WO (1) WO2000039298A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6613337B1 (en) * 1997-02-12 2003-09-02 Corixa Corporation Leishmania antigens for use in the therapy and diagnosis of leishmaniasis
ES2169995B1 (es) * 2000-04-17 2003-12-01 Leti Lab Composicion a base de la proteina lip2a y su uso en la preparacion de un medicamento para suscitar una respuesta inmune contra un antigeno.
US6673351B1 (en) 2001-03-16 2004-01-06 Astralis, Llc Compositions and methods for the treatment and clinical remission of psoriasis
WO2006058243A2 (en) * 2004-11-24 2006-06-01 Yale University Leishmania antigens and related compositions and uses
WO2009090175A1 (en) * 2008-01-18 2009-07-23 Laboratorios Leti, S.L. Unipersonal Vaccine comprising a ribosomal protein extract (rpe) and optionally a th1-promoting adjuvant
PE20120818A1 (es) * 2009-07-13 2012-07-12 Leti Sl Lab Diagnostico de una parasitosis tal como la leishmaniasis usando un extracto de proteinas ribosomicas (rpe)
SA110310855B1 (ar) 2009-11-13 2014-09-16 Laboratories Leti S L Unipersonal استخدام مصدر l3 و/ أو l5 كلقاح أو كوسيلة تشخيصية لمرض طفيلي
BR102019003639A2 (pt) * 2019-02-22 2021-11-16 Fundação Oswaldo Cruz Proteína quimérica, seu método para produção e uso, bem como molécula de ácido nucleico, cassete de expressão, vetor de expressão, célula hospedeira, composição para diagnóstico de leishmaniose, kit de diagnóstico de leishmaniose e método de diagnóstico de leishmaniose in vitro
ES2795149B2 (es) 2020-06-08 2022-07-04 Univ Madrid Complutense Quimera sintetica multiepitopica como vacuna y tratamiento frente a leishmaniosis en mamiferos
CN112662694A (zh) * 2020-12-25 2021-04-16 康九生物科技(长春)有限公司 一种麦芽糖结合蛋白、麦芽糖结合蛋白表达载体、重组工程菌及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0703295A1 (en) * 1994-09-26 1996-03-27 Institut Pasteur Vaccine composition comprising recombinant BCG expressing gp 63 fusion protein
US5912166A (en) * 1995-04-21 1999-06-15 Corixa Corporation Compounds and methods for diagnosis of leishmaniasis
ES2133236B1 (es) * 1997-06-27 2000-04-16 Leti Lab Gen quimerico formado por las secuencias de dna que codifican los determinantes antigenicos de cuatro proteinas de l. infantum, aplicable para el diagnostico serologico de leishmaniosis canina y proteina obtenida.

Also Published As

Publication number Publication date
ES2273519T3 (es) 2007-05-01
CY2016033I2 (el) 2017-03-15
SI1624063T1 (sl) 2009-08-31
ES2326174T3 (es) 2009-10-02
CY1105331T1 (el) 2010-03-03
PT1141305E (pt) 2006-10-31
AU759316B2 (en) 2003-04-10
EP1141305B1 (en) 2006-05-24
MXPA01006548A (es) 2003-03-27
HUP0104743A2 (hu) 2002-03-28
BRPI9916549B1 (pt) 2018-10-02
BRPI9916549B8 (pt) 2022-08-30
HRP20010554A2 (en) 2002-08-31
BE2016C049I2 (enExample) 2019-03-05
NL300830I1 (nl) 2016-09-28
NL300830I2 (nl) 2020-08-31
HUP0104743A3 (en) 2004-10-28
WO2000039298A1 (en) 2000-07-06
BG65569B1 (bg) 2008-12-30
CN1335889A (zh) 2002-02-13
BR9916549A (pt) 2005-01-04
BG105725A (en) 2002-06-28
DE69940793D1 (de) 2009-06-04
CY1109221T1 (el) 2014-07-02
IL143956A (en) 2010-11-30
PT1624063E (pt) 2009-06-19
IL143956A0 (en) 2002-04-21
LU93259I2 (fr) 2016-12-06
DE69931518T2 (de) 2006-12-21
DK1141305T3 (da) 2006-09-25
TR200102655T2 (tr) 2002-04-22
DE69931518D1 (de) 2006-06-29
AU2434200A (en) 2000-07-31
EP1141305A1 (en) 2001-10-10
ATE429498T1 (de) 2009-05-15
CZ20012360A3 (cs) 2001-10-17
ATE327332T1 (de) 2006-06-15
CY2016033I1 (el) 2017-03-15

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