CY1105331T1 - Χιμαιρικα γονιδια που κωδικοποιουν τους αντιγονικους καθοριστες τεσσαρων πρωτεϊνων του l. infantum - Google Patents
Χιμαιρικα γονιδια που κωδικοποιουν τους αντιγονικους καθοριστες τεσσαρων πρωτεϊνων του l. infantumInfo
- Publication number
- CY1105331T1 CY1105331T1 CY20061101190T CY061101190T CY1105331T1 CY 1105331 T1 CY1105331 T1 CY 1105331T1 CY 20061101190 T CY20061101190 T CY 20061101190T CY 061101190 T CY061101190 T CY 061101190T CY 1105331 T1 CY1105331 T1 CY 1105331T1
- Authority
- CY
- Cyprus
- Prior art keywords
- infantum
- antigenic determinants
- genes encoding
- chimeric genes
- protein antigenic
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 241000222697 Leishmania infantum Species 0.000 title abstract 2
- 230000000890 antigenic effect Effects 0.000 title abstract 2
- 206010047505 Visceral leishmaniasis Diseases 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 208000004554 Leishmaniasis Diseases 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Tropical Medicine & Parasitology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Η παρούσα εφεύρεση αναφέρεται σε μια φαρμακευτική σύνθεση για την αποτροπή και θεραπεία, ανθρώπου ή ζώου, της λεϊσμανίασης. Η φαρμακευτική σύνθεση περιέχει την πρωτεΐνη χίμαιρα Q, η οποία είναι το προϊόν ενός χιμαιρικού γονιδίου που κωδικοποιεί τους αντιγονικούς καθοριστές τεσσάρων πρωτεϊνών του Leishmania infantum.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11382598P | 1998-12-23 | 1998-12-23 | |
| CA2256124A CA2256124C (en) | 1998-12-23 | 1998-12-23 | Chimeric gene formed of the dna sequences that encode the antigenic determinants of four proteins of l. infantum, and protein encoded by said gene, and pharmaceutical composition useful for preventing and/or treating leishmaniosis in animals or humans |
| PCT/EP1999/010441 WO2000039298A1 (en) | 1998-12-23 | 1999-12-23 | Chimeric gene encoding the antigenic determinants of four proteins of l. infantum |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1105331T1 true CY1105331T1 (el) | 2010-03-03 |
Family
ID=25680668
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20061101190T CY1105331T1 (el) | 1998-12-23 | 2006-08-24 | Χιμαιρικα γονιδια που κωδικοποιουν τους αντιγονικους καθοριστες τεσσαρων πρωτεϊνων του l. infantum |
| CY20091100739T CY1109221T1 (el) | 1998-12-23 | 2009-07-14 | Χιμαιρικο γονιδιο που κωδικοποιει τους αντιγονικους καθοριστες τεσσαρων πρωτεϊνων του l. infantum |
| CY2016033C CY2016033I2 (el) | 1998-12-23 | 2016-10-20 | Χιμαιρικα γονιδια που κωδικοποιουν τους αντιγονικους καθοριστες τεσσαρων πρωτεϊνων του l. infantum |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20091100739T CY1109221T1 (el) | 1998-12-23 | 2009-07-14 | Χιμαιρικο γονιδιο που κωδικοποιει τους αντιγονικους καθοριστες τεσσαρων πρωτεϊνων του l. infantum |
| CY2016033C CY2016033I2 (el) | 1998-12-23 | 2016-10-20 | Χιμαιρικα γονιδια που κωδικοποιουν τους αντιγονικους καθοριστες τεσσαρων πρωτεϊνων του l. infantum |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP1141305B1 (el) |
| CN (1) | CN1158387C (el) |
| AT (2) | ATE429498T1 (el) |
| AU (1) | AU759316B2 (el) |
| BE (1) | BE2016C049I2 (el) |
| BG (1) | BG65569B1 (el) |
| BR (1) | BRPI9916549B8 (el) |
| CY (3) | CY1105331T1 (el) |
| CZ (1) | CZ20012360A3 (el) |
| DE (2) | DE69931518T2 (el) |
| DK (1) | DK1141305T3 (el) |
| ES (2) | ES2326174T3 (el) |
| HR (1) | HRP20010554A2 (el) |
| HU (1) | HUP0104743A3 (el) |
| IL (2) | IL143956A0 (el) |
| LU (1) | LU93259I2 (el) |
| MX (1) | MXPA01006548A (el) |
| NL (1) | NL300830I2 (el) |
| PT (2) | PT1624063E (el) |
| SI (1) | SI1624063T1 (el) |
| TR (1) | TR200102655T2 (el) |
| WO (1) | WO2000039298A1 (el) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6613337B1 (en) * | 1997-02-12 | 2003-09-02 | Corixa Corporation | Leishmania antigens for use in the therapy and diagnosis of leishmaniasis |
| ES2169995B1 (es) * | 2000-04-17 | 2003-12-01 | Leti Lab | Composicion a base de la proteina lip2a y su uso en la preparacion de un medicamento para suscitar una respuesta inmune contra un antigeno. |
| US6673351B1 (en) | 2001-03-16 | 2004-01-06 | Astralis, Llc | Compositions and methods for the treatment and clinical remission of psoriasis |
| WO2006058243A2 (en) * | 2004-11-24 | 2006-06-01 | Yale University | Leishmania antigens and related compositions and uses |
| PT2231700E (pt) * | 2008-01-18 | 2014-07-31 | Leti S L Unipersonal Lab | Vacina que compreende extrato de proteína ribossomal (rpe) e um auxiliar estimulante th1 como opção |
| WO2011006891A1 (en) * | 2009-07-13 | 2011-01-20 | Laboratorios Leti, S.L. | Diagnosis of a parasitic disease such as leishmaniasis using ribosomal protein extract (rpe) |
| SA110310855B1 (ar) | 2009-11-13 | 2014-09-16 | Laboratories Leti S L Unipersonal | استخدام مصدر l3 و/ أو l5 كلقاح أو كوسيلة تشخيصية لمرض طفيلي |
| BR102019003639A2 (pt) * | 2019-02-22 | 2021-11-16 | Fundação Oswaldo Cruz | Proteína quimérica, seu método para produção e uso, bem como molécula de ácido nucleico, cassete de expressão, vetor de expressão, célula hospedeira, composição para diagnóstico de leishmaniose, kit de diagnóstico de leishmaniose e método de diagnóstico de leishmaniose in vitro |
| ES2795149B2 (es) | 2020-06-08 | 2022-07-04 | Univ Madrid Complutense | Quimera sintetica multiepitopica como vacuna y tratamiento frente a leishmaniosis en mamiferos |
| CN112662694A (zh) * | 2020-12-25 | 2021-04-16 | 康九生物科技(长春)有限公司 | 一种麦芽糖结合蛋白、麦芽糖结合蛋白表达载体、重组工程菌及其应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0703295A1 (en) * | 1994-09-26 | 1996-03-27 | Institut Pasteur | Vaccine composition comprising recombinant BCG expressing gp 63 fusion protein |
| US5912166A (en) * | 1995-04-21 | 1999-06-15 | Corixa Corporation | Compounds and methods for diagnosis of leishmaniasis |
| ES2133236B1 (es) * | 1997-06-27 | 2000-04-16 | Leti Lab | Gen quimerico formado por las secuencias de dna que codifican los determinantes antigenicos de cuatro proteinas de l. infantum, aplicable para el diagnostico serologico de leishmaniosis canina y proteina obtenida. |
-
1999
- 1999-12-23 IL IL14395699A patent/IL143956A0/xx unknown
- 1999-12-23 BR BRPI9916549A patent/BRPI9916549B8/pt not_active IP Right Cessation
- 1999-12-23 TR TR2001/02655T patent/TR200102655T2/xx unknown
- 1999-12-23 AU AU24342/00A patent/AU759316B2/en not_active Expired
- 1999-12-23 HU HU0104743A patent/HUP0104743A3/hu unknown
- 1999-12-23 ES ES05109393T patent/ES2326174T3/es not_active Expired - Lifetime
- 1999-12-23 CZ CZ20012360A patent/CZ20012360A3/cs unknown
- 1999-12-23 PT PT05109393T patent/PT1624063E/pt unknown
- 1999-12-23 DE DE69931518T patent/DE69931518T2/de not_active Expired - Lifetime
- 1999-12-23 PT PT99967987T patent/PT1141305E/pt unknown
- 1999-12-23 ES ES99967987T patent/ES2273519T3/es not_active Expired - Lifetime
- 1999-12-23 DE DE69940793T patent/DE69940793D1/de not_active Expired - Lifetime
- 1999-12-23 AT AT05109393T patent/ATE429498T1/de not_active IP Right Cessation
- 1999-12-23 AT AT99967987T patent/ATE327332T1/de active
- 1999-12-23 DK DK99967987T patent/DK1141305T3/da active
- 1999-12-23 CN CNB998163066A patent/CN1158387C/zh not_active Expired - Lifetime
- 1999-12-23 EP EP99967987A patent/EP1141305B1/en not_active Expired - Lifetime
- 1999-12-23 MX MXPA01006548A patent/MXPA01006548A/es active IP Right Grant
- 1999-12-23 SI SI9931029T patent/SI1624063T1/sl unknown
- 1999-12-23 WO PCT/EP1999/010441 patent/WO2000039298A1/en active IP Right Grant
-
2001
- 2001-06-24 IL IL143956A patent/IL143956A/en not_active IP Right Cessation
- 2001-07-23 BG BG105725A patent/BG65569B1/bg unknown
- 2001-07-23 HR HR20010554A patent/HRP20010554A2/hr not_active Application Discontinuation
-
2006
- 2006-08-24 CY CY20061101190T patent/CY1105331T1/el unknown
-
2009
- 2009-07-14 CY CY20091100739T patent/CY1109221T1/el unknown
-
2016
- 2016-09-22 NL NL300830C patent/NL300830I2/nl unknown
- 2016-10-06 BE BE2016C049C patent/BE2016C049I2/nl unknown
- 2016-10-06 LU LU93259C patent/LU93259I2/fr unknown
- 2016-10-20 CY CY2016033C patent/CY2016033I2/el unknown
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