CY1110634T1 - Μεθοδοι προληψης και θεραπειας της νοσου του αλτσχαϊμερ (ad) - Google Patents

Μεθοδοι προληψης και θεραπειας της νοσου του αλτσχαϊμερ (ad)

Info

Publication number
CY1110634T1
CY1110634T1 CY20101100399T CY101100399T CY1110634T1 CY 1110634 T1 CY1110634 T1 CY 1110634T1 CY 20101100399 T CY20101100399 T CY 20101100399T CY 101100399 T CY101100399 T CY 101100399T CY 1110634 T1 CY1110634 T1 CY 1110634T1
Authority
CY
Cyprus
Prior art keywords
amino acid
except
alzheimer
disease
prevention
Prior art date
Application number
CY20101100399T
Other languages
English (en)
Inventor
Frank Mattner
Original Assignee
Affiris Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Affiris Ag filed Critical Affiris Ag
Publication of CY1110634T1 publication Critical patent/CY1110634T1/el

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Neurology (AREA)
  • Toxicology (AREA)
  • Neurosurgery (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)

Abstract

Η εφεύρεση σχετίζεται με τη χρήση ένωσης που περιλαμβάνει την παρακάτω αμινοξική ακολουθία Χ1Χ2Χ3Χ4Χ5Χ6, όπου το Χ1 είναι αμινοξύ, εκτός C, όπου το Χ2 είναι αμινοξύ, εκτός C, όπου το Χ3 είναι αμινοξύ, εκτός C, όπου το Χ4 είναι αμινοξύ, εκτός C, όπου το Χ5 είναι αμινοξύ, εκτός C, όπου το Χ6 είναι αμινοξύ, εκτός C, και όπου το Χ1Χ2Χ3Χ4Χ5Χ6 δεν είναι DAEFRH, με την εν λόγω ένωση να διαθέτει ικανότητα δέσμευσης σε αντίσωμα που είναι ειδικό για τη φυσική αμινοτελική ακολουθία Αβ42 DAEFRH, και της οποίας τα πενταμερή διαθέτουν ικανότητα δέσμευσης στο εν λόγω αντίσωμα που είναι ειδικό για τη φυσική αμινοτελική ακολουθία Αβ42 DAEFRH, για την παρασκευή εμβολίου για τη νόσο του Αλτσχάιμερ.
CY20101100399T 2003-01-14 2010-05-07 Μεθοδοι προληψης και θεραπειας της νοσου του αλτσχαϊμερ (ad) CY1110634T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AT362003 2003-01-14
AT0146403A AT413945B (de) 2003-01-14 2003-09-17 Impfstoff für die alzheimer-krankheit
EP04701585A EP1583774B1 (en) 2003-01-14 2004-01-13 Methods for preventing and treating alzheimer's disease (ad)

Publications (1)

Publication Number Publication Date
CY1110634T1 true CY1110634T1 (el) 2015-04-29

Family

ID=32714004

Family Applications (2)

Application Number Title Priority Date Filing Date
CY20081100069T CY1107146T1 (el) 2003-01-14 2008-01-17 Μεθοδοι για προληψη και θεραπεια ασθενειας alzheimer (ad)
CY20101100399T CY1110634T1 (el) 2003-01-14 2010-05-07 Μεθοδοι προληψης και θεραπειας της νοσου του αλτσχαϊμερ (ad)

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CY20081100069T CY1107146T1 (el) 2003-01-14 2008-01-17 Μεθοδοι για προληψη και θεραπεια ασθενειας alzheimer (ad)

Country Status (15)

Country Link
US (2) US7732568B2 (el)
EP (2) EP1583774B1 (el)
JP (2) JP4547373B2 (el)
CN (2) CN1826354B (el)
AT (3) AT413945B (el)
CA (1) CA2513218C (el)
CY (2) CY1107146T1 (el)
DE (2) DE602004025668D1 (el)
DK (2) DK1679319T3 (el)
ES (2) ES2296084T3 (el)
HK (1) HK1091499A1 (el)
PL (1) PL209989B1 (el)
PT (2) PT1583774E (el)
SI (1) SI1583774T1 (el)
WO (1) WO2004062556A2 (el)

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AT500483B1 (de) 2004-07-13 2006-01-15 Mattner Frank Dr Set zur vorbeugung oder behandlung der alzheimer'schen erkrankung
AT413946B (de) * 2004-07-13 2006-07-15 Mattner Frank Dr Impfstoff gegen die alzheimer-krankheit
PT1954718E (pt) 2005-11-30 2014-12-16 Abbvie Inc Anticorpos anti-globulómeros aβ, suas porções de ligação ao antigénio, correspondentes hibridomas, ácidos nucleicos, vectores, células hospedeiras, métodos de produção dos ditos anticorpos, composições compreendendo os ditos anticorpos, usos dos ditos anticorpos e métodos para uso dos ditos anticorpos
DK1976877T4 (en) 2005-11-30 2017-01-16 Abbvie Inc Monoclonal antibodies to amyloid beta protein and uses thereof
KR20150098683A (ko) * 2005-12-12 2015-08-28 에이씨 이뮨 에스.에이. 치료적 특성을 갖는 베타 1-42 특이적인 단일클론성 항체
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Also Published As

Publication number Publication date
CN102526699A (zh) 2012-07-04
US20110015131A1 (en) 2011-01-20
SI1583774T1 (sl) 2010-06-30
ATA14642003A (de) 2005-11-15
US7732568B2 (en) 2010-06-08
DK1583774T3 (da) 2010-05-03
EP1583774B1 (en) 2010-02-24
US20060111301A1 (en) 2006-05-25
JP4547373B2 (ja) 2010-09-22
EP1583774A2 (en) 2005-10-12
CY1107146T1 (el) 2012-05-23
EP1679319A1 (en) 2006-07-12
DE602004025668D1 (de) 2010-04-08
AU2004204349A1 (en) 2004-07-29
DE602004009705T2 (de) 2008-06-05
JP5282058B2 (ja) 2013-09-04
DE602004009705D1 (de) 2007-12-06
PT1679319E (pt) 2008-01-10
ATE458753T1 (de) 2010-03-15
PL209989B1 (pl) 2011-11-30
JP2006515876A (ja) 2006-06-08
DK1679319T3 (da) 2008-01-28
WO2004062556A8 (en) 2004-10-21
WO2004062556A3 (en) 2004-09-16
CA2513218C (en) 2013-06-25
PT1583774E (pt) 2010-04-07
WO2004062556A2 (en) 2004-07-29
JP2010174024A (ja) 2010-08-12
CN1826354B (zh) 2014-01-08
EP1679319B1 (en) 2007-10-24
HK1091499A1 (en) 2007-01-19
PL378333A1 (pl) 2006-03-20
CN1826354A (zh) 2006-08-30
AT413945B (de) 2006-07-15
ES2339447T3 (es) 2010-05-20
CA2513218A1 (en) 2004-07-29
ES2339447T8 (es) 2011-05-26
ES2296084T3 (es) 2008-04-16
ATE376559T1 (de) 2007-11-15

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