HUP0104743A2 - Az L. infantum proteinjeinek antigéndeterminánsait kódoló kiméragén - Google Patents

Az L. infantum proteinjeinek antigéndeterminánsait kódoló kiméragén

Info

Publication number
HUP0104743A2
HUP0104743A2 HU0104743A HUP0104743A HUP0104743A2 HU P0104743 A2 HUP0104743 A2 HU P0104743A2 HU 0104743 A HU0104743 A HU 0104743A HU P0104743 A HUP0104743 A HU P0104743A HU P0104743 A2 HUP0104743 A2 HU P0104743A2
Authority
HU
Hungary
Prior art keywords
infantum
proteins
gene encoding
antigenic determinants
chimeric gene
Prior art date
Application number
HU0104743A
Other languages
English (en)
Inventor
Carlos Bedate Alonso
Original Assignee
C.B.F. Leti S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA2256124A external-priority patent/CA2256124C/en
Application filed by C.B.F. Leti S.A. filed Critical C.B.F. Leti S.A.
Publication of HUP0104743A2 publication Critical patent/HUP0104743A2/hu
Publication of HUP0104743A3 publication Critical patent/HUP0104743A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

A találmány tárgyát emberi vagy állati Leishmaniasis megelőzésére éskezelésére szolgáló gyógyászati készítmény képezi. A gyógyászatikészítmény az L. infantum<> négy proteinjének antigéndeterminánsaitkódoló kiméragén termékét, a <Q< proteinkimérát tartalmazza. Atalálmány tárgyát képezik továbbá a kiméragén, annak proteinterméke,az azt tartalmazó gazda, eljárások a protein előállítására ésgyógyászati alkalmazásai. Ó
HU0104743A 1998-12-23 1999-12-23 Chimeric gene encoding the antigenic determinants of four proteins of l. infantum HUP0104743A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11382598P 1998-12-23 1998-12-23
CA2256124A CA2256124C (en) 1998-12-23 1998-12-23 Chimeric gene formed of the dna sequences that encode the antigenic determinants of four proteins of l. infantum, and protein encoded by said gene, and pharmaceutical composition useful for preventing and/or treating leishmaniosis in animals or humans
PCT/EP1999/010441 WO2000039298A1 (en) 1998-12-23 1999-12-23 Chimeric gene encoding the antigenic determinants of four proteins of l. infantum

Publications (2)

Publication Number Publication Date
HUP0104743A2 true HUP0104743A2 (hu) 2002-03-28
HUP0104743A3 HUP0104743A3 (en) 2004-10-28

Family

ID=25680668

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0104743A HUP0104743A3 (en) 1998-12-23 1999-12-23 Chimeric gene encoding the antigenic determinants of four proteins of l. infantum

Country Status (22)

Country Link
EP (1) EP1141305B1 (hu)
CN (1) CN1158387C (hu)
AT (2) ATE429498T1 (hu)
AU (1) AU759316B2 (hu)
BE (1) BE2016C049I2 (hu)
BG (1) BG65569B1 (hu)
BR (1) BRPI9916549B8 (hu)
CY (3) CY1105331T1 (hu)
CZ (1) CZ20012360A3 (hu)
DE (2) DE69931518T2 (hu)
DK (1) DK1141305T3 (hu)
ES (2) ES2326174T3 (hu)
HR (1) HRP20010554A2 (hu)
HU (1) HUP0104743A3 (hu)
IL (2) IL143956A0 (hu)
LU (1) LU93259I2 (hu)
MX (1) MXPA01006548A (hu)
NL (1) NL300830I2 (hu)
PT (2) PT1624063E (hu)
SI (1) SI1624063T1 (hu)
TR (1) TR200102655T2 (hu)
WO (1) WO2000039298A1 (hu)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6613337B1 (en) * 1997-02-12 2003-09-02 Corixa Corporation Leishmania antigens for use in the therapy and diagnosis of leishmaniasis
ES2169995B1 (es) * 2000-04-17 2003-12-01 Leti Lab Composicion a base de la proteina lip2a y su uso en la preparacion de un medicamento para suscitar una respuesta inmune contra un antigeno.
US6673351B1 (en) 2001-03-16 2004-01-06 Astralis, Llc Compositions and methods for the treatment and clinical remission of psoriasis
WO2006058243A2 (en) * 2004-11-24 2006-06-01 Yale University Leishmania antigens and related compositions and uses
PT2231700E (pt) * 2008-01-18 2014-07-31 Leti S L Unipersonal Lab Vacina que compreende extrato de proteína ribossomal (rpe) e um auxiliar estimulante th1 como opção
WO2011006891A1 (en) * 2009-07-13 2011-01-20 Laboratorios Leti, S.L. Diagnosis of a parasitic disease such as leishmaniasis using ribosomal protein extract (rpe)
SA110310855B1 (ar) 2009-11-13 2014-09-16 Laboratories Leti S L Unipersonal استخدام مصدر l3 و/ أو l5 كلقاح أو كوسيلة تشخيصية لمرض طفيلي
BR102019003639A2 (pt) * 2019-02-22 2021-11-16 Fundação Oswaldo Cruz Proteína quimérica, seu método para produção e uso, bem como molécula de ácido nucleico, cassete de expressão, vetor de expressão, célula hospedeira, composição para diagnóstico de leishmaniose, kit de diagnóstico de leishmaniose e método de diagnóstico de leishmaniose in vitro
ES2795149B2 (es) 2020-06-08 2022-07-04 Univ Madrid Complutense Quimera sintetica multiepitopica como vacuna y tratamiento frente a leishmaniosis en mamiferos
CN112662694A (zh) * 2020-12-25 2021-04-16 康九生物科技(长春)有限公司 一种麦芽糖结合蛋白、麦芽糖结合蛋白表达载体、重组工程菌及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0703295A1 (en) * 1994-09-26 1996-03-27 Institut Pasteur Vaccine composition comprising recombinant BCG expressing gp 63 fusion protein
US5912166A (en) * 1995-04-21 1999-06-15 Corixa Corporation Compounds and methods for diagnosis of leishmaniasis
ES2133236B1 (es) * 1997-06-27 2000-04-16 Leti Lab Gen quimerico formado por las secuencias de dna que codifican los determinantes antigenicos de cuatro proteinas de l. infantum, aplicable para el diagnostico serologico de leishmaniosis canina y proteina obtenida.

Also Published As

Publication number Publication date
DE69931518T2 (de) 2006-12-21
IL143956A0 (en) 2002-04-21
AU759316B2 (en) 2003-04-10
ATE327332T1 (de) 2006-06-15
HUP0104743A3 (en) 2004-10-28
ATE429498T1 (de) 2009-05-15
CN1158387C (zh) 2004-07-21
WO2000039298A1 (en) 2000-07-06
CY2016033I1 (el) 2017-03-15
DE69931518D1 (de) 2006-06-29
CZ20012360A3 (cs) 2001-10-17
CY2016033I2 (el) 2017-03-15
PT1624063E (pt) 2009-06-19
AU2434200A (en) 2000-07-31
CY1105331T1 (el) 2010-03-03
BG105725A (en) 2002-06-28
PT1141305E (pt) 2006-10-31
DE69940793D1 (de) 2009-06-04
NL300830I1 (nl) 2016-09-28
ES2326174T3 (es) 2009-10-02
CY1109221T1 (el) 2014-07-02
BG65569B1 (bg) 2008-12-30
BRPI9916549B1 (pt) 2018-10-02
ES2273519T3 (es) 2007-05-01
MXPA01006548A (es) 2003-03-27
DK1141305T3 (da) 2006-09-25
BR9916549A (pt) 2005-01-04
SI1624063T1 (sl) 2009-08-31
EP1141305A1 (en) 2001-10-10
BRPI9916549B8 (pt) 2022-08-30
HRP20010554A2 (en) 2002-08-31
EP1141305B1 (en) 2006-05-24
IL143956A (en) 2010-11-30
CN1335889A (zh) 2002-02-13
BE2016C049I2 (hu) 2019-03-05
LU93259I2 (fr) 2016-12-06
TR200102655T2 (tr) 2002-04-22
NL300830I2 (nl) 2020-08-31

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