CN115038796A - 含有微小rna的体液提取物 - Google Patents

含有微小rna的体液提取物

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Publication number
CN115038796A
CN115038796A CN202080063346.XA CN202080063346A CN115038796A CN 115038796 A CN115038796 A CN 115038796A CN 202080063346 A CN202080063346 A CN 202080063346A CN 115038796 A CN115038796 A CN 115038796A
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mir
hsa
micrornas
microrna
urine
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安井隆雄
马场嘉信
市川裕树
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Kelaihe Co ltd
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Kelaihe Co ltd
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

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CN202080063346.XA 2019-09-09 2020-09-08 含有微小rna的体液提取物 Pending CN115038796A (zh)

Applications Claiming Priority (3)

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JP2019193847 2019-09-09
JP2019-193847 2019-09-09
PCT/JP2020/037487 WO2021049671A1 (ja) 2019-09-09 2020-09-08 マイクロｒｎａを含む体液抽出物

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US (1) US20230265521A1 (https=)
EP (1) EP4029940A4 (https=)
JP (2) JP7660898B2 (https=)
CN (1) CN115038796A (https=)
WO (1) WO2021049671A1 (https=)

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110799648A (zh) * 2017-06-29 2020-02-14 东丽株式会社 用于检测肺癌的试剂盒、装置和方法
CN111534598A (zh) * 2020-06-11 2020-08-14 广西医科大学第一附属医院 与结直肠癌患者肿瘤突变负荷水平相关的miRNA标志物及应用
CN113134010A (zh) * 2020-01-20 2021-07-20 上海市计划生育科学研究所 一种靶向雌激素受体α的微小RNA及其抗肿瘤用途
CN115896295A (zh) * 2022-12-30 2023-04-04 中国科学技术大学 辅助诊断胆囊炎或预测胆囊炎合并肝损伤的miRNA标志物
CN116024330A (zh) * 2022-12-07 2023-04-28 中国医学科学院北京协和医院 miR-137-3p在薄型子宫内膜中的应用
CN116121382A (zh) * 2022-12-15 2023-05-16 康德（深圳）生物技术有限公司 一种用于胰腺癌精准用药生物标志物的筛选方法及其专用标志物
CN116144781A (zh) * 2023-03-23 2023-05-23 刘忠祥 用于检测肺腺癌的标记物、引物组以及试剂盒
CN116144777A (zh) * 2022-12-30 2023-05-23 贵州医科大学 用于癌症筛查的基于m1A相关miRNA诊断试剂、模型及制备方法
CN116898868A (zh) * 2023-05-19 2023-10-20 青岛大学附属医院 MiR-1909-5p在制备治疗血管内皮细胞铁死亡和/或主动脉夹层产品中的应用
CN117530932A (zh) * 2024-01-08 2024-02-09 中国药科大学 一种抑制肿瘤生长及肺转移的人工外泌体及其应用
CN117802235A (zh) * 2022-09-30 2024-04-02 上海思路迪生物医学科技有限公司 血液胞外囊泡miRNA在卵巢癌诊断中的应用
CN117802232A (zh) * 2022-09-30 2024-04-02 上海思路迪生物医学科技有限公司 血液小型胞外囊泡miRNA在卵巢癌诊断中的应用
CN118932040A (zh) * 2024-07-22 2024-11-12 南通大学附属医院 miR-3591-5p作为先天性心脏病合并肺动脉高压诊断标志的应用及检测试剂盒
CN119144728A (zh) * 2024-11-19 2024-12-17 四川大学华西医院 原发性肝癌的MicroRNA标志物的引物、试剂盒和应用

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EP4211273B1 (en) * 2020-09-14 2025-10-29 Institut National de la Santé et de la Recherche Médicale Method to treat and stratificate a patient suffering from a cancer
EP4314321A4 (en) * 2021-03-24 2025-06-04 Craif Inc. MIARN, COMPOSITIONS AND METHODS OF USE THEREOF
CN113249488A (zh) * 2021-06-29 2021-08-13 中国人民解放军空军军医大学 基于外泌体miRNA-4433-5p表达水平的胃癌恶液质早期诊断试剂盒
CN115198014A (zh) * 2021-12-03 2022-10-18 武汉博越致和生物科技有限公司 一种用于胰腺癌早期诊断的外泌体miRNA标志物组合及检测试剂盒
CN114540491B (zh) * 2021-12-08 2024-01-30 北京尧景基因技术有限公司 一种基于岩藻糖基化细胞外囊泡中差异化表达miRNA的肝癌预测模型建立及应用
CN114672560B (zh) * 2022-01-12 2025-09-26 北京艾克伦医疗科技有限公司 通过外泌体miRNA标志物鉴定结直肠癌状态的检测试剂盒和方法
CN115141882A (zh) * 2022-02-23 2022-10-04 南方医科大学南方医院 黄韧带肥厚早期诊断用miRNA生物标志物、试剂盒及应用
JP2025506080A (ja) * 2022-03-09 2025-03-07 Ｃｒａｉｆ株式会社 疾患アウトカムを分類する方法
CN114686586B (zh) * 2022-05-05 2023-10-20 首都医科大学附属北京胸科医院 一种用于诊断结核性胸膜炎的分子标志物组合物及其应用
CN114686593B (zh) * 2022-05-30 2022-10-25 深圳市慢性病防治中心(深圳市皮肤病防治研究所、深圳市肺部疾病防治研究所) 与乳腺癌有关的外泌体SmallRNA及其应用
CA3254846A1 (en) * 2022-06-10 2023-12-14 City Of Hope Biomarkers in pancreatic cancer
CN114959014B (zh) * 2022-06-17 2023-03-31 中山大学附属第一医院 血清miRNAs作为绝经后骨质疏松联合诊断标志物的应用
US20250382673A1 (en) * 2022-07-01 2025-12-18 City Of Hope Biomarkers in colorectal cancer
CN116492464B (zh) * 2023-04-12 2025-08-19 天津医科大学总医院 TNFRSF1A抑制剂miR-3059-5p在治疗脑卒中疾病中的用途
WO2024232682A1 (ko) * 2023-05-09 2024-11-14 솔바이오 주식회사 전립선암의 진단 및 치료 타겟으로서 mir-6880-5p

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Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110799648A (zh) * 2017-06-29 2020-02-14 东丽株式会社 用于检测肺癌的试剂盒、装置和方法
CN110799648B (zh) * 2017-06-29 2024-03-22 东丽株式会社 用于检测肺癌的试剂盒、装置和方法
CN113134010B (zh) * 2020-01-20 2023-09-01 上海市生物医药技术研究院 一种靶向雌激素受体α的微小RNA及其抗肿瘤用途
CN113134010A (zh) * 2020-01-20 2021-07-20 上海市计划生育科学研究所 一种靶向雌激素受体α的微小RNA及其抗肿瘤用途
CN111534598A (zh) * 2020-06-11 2020-08-14 广西医科大学第一附属医院 与结直肠癌患者肿瘤突变负荷水平相关的miRNA标志物及应用
CN111534598B (zh) * 2020-06-11 2023-05-02 广西医科大学第一附属医院 与结直肠癌患者肿瘤突变负荷水平相关的miRNA标志物及应用
CN117802235A (zh) * 2022-09-30 2024-04-02 上海思路迪生物医学科技有限公司 血液胞外囊泡miRNA在卵巢癌诊断中的应用
CN117802232A (zh) * 2022-09-30 2024-04-02 上海思路迪生物医学科技有限公司 血液小型胞外囊泡miRNA在卵巢癌诊断中的应用
CN116024330A (zh) * 2022-12-07 2023-04-28 中国医学科学院北京协和医院 miR-137-3p在薄型子宫内膜中的应用
CN116024330B (zh) * 2022-12-07 2023-12-01 中国医学科学院北京协和医院 miR-137-3p在薄型子宫内膜中的应用
CN116121382A (zh) * 2022-12-15 2023-05-16 康德（深圳）生物技术有限公司 一种用于胰腺癌精准用药生物标志物的筛选方法及其专用标志物
CN116144777A (zh) * 2022-12-30 2023-05-23 贵州医科大学 用于癌症筛查的基于m1A相关miRNA诊断试剂、模型及制备方法
CN115896295A (zh) * 2022-12-30 2023-04-04 中国科学技术大学 辅助诊断胆囊炎或预测胆囊炎合并肝损伤的miRNA标志物
CN116144781A (zh) * 2023-03-23 2023-05-23 刘忠祥 用于检测肺腺癌的标记物、引物组以及试剂盒
CN116898868A (zh) * 2023-05-19 2023-10-20 青岛大学附属医院 MiR-1909-5p在制备治疗血管内皮细胞铁死亡和/或主动脉夹层产品中的应用
CN116898868B (zh) * 2023-05-19 2024-02-06 青岛大学附属医院 MiR-1909-5p在制备治疗血管内皮细胞铁死亡和/或主动脉夹层产品中的应用
CN117530932A (zh) * 2024-01-08 2024-02-09 中国药科大学 一种抑制肿瘤生长及肺转移的人工外泌体及其应用
CN117530932B (zh) * 2024-01-08 2024-04-26 中国药科大学 一种抑制肿瘤生长及肺转移的人工外泌体及其应用
CN118932040A (zh) * 2024-07-22 2024-11-12 南通大学附属医院 miR-3591-5p作为先天性心脏病合并肺动脉高压诊断标志的应用及检测试剂盒
CN119144728A (zh) * 2024-11-19 2024-12-17 四川大学华西医院 原发性肝癌的MicroRNA标志物的引物、试剂盒和应用

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EP4029940A1 (en) 2022-07-20
EP4029940A4 (en) 2024-02-28
JP2025098184A (ja) 2025-07-01
JP7660898B2 (ja) 2025-04-14
US20230265521A1 (en) 2023-08-24
WO2021049671A1 (ja) 2021-03-18

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