CN1128135C - 还原α-氨基酮的方法 - Google Patents

还原α-氨基酮的方法 Download PDF

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Publication number
CN1128135C
CN1128135C CN98800734A CN98800734A CN1128135C CN 1128135 C CN1128135 C CN 1128135C CN 98800734 A CN98800734 A CN 98800734A CN 98800734 A CN98800734 A CN 98800734A CN 1128135 C CN1128135 C CN 1128135C
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CN
China
Prior art keywords
general formula
chloro
benzyl
carbamate
oxopropyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN98800734A
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English (en)
Chinese (zh)
Other versions
CN1228081A (zh
Inventor
松尾和彦
松本慎吾
井上健二
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Kaneka Corp
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Kaneka Corp
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Publication date
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Publication of CN1228081A publication Critical patent/CN1228081A/zh
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Publication of CN1128135C publication Critical patent/CN1128135C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/06Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN98800734A 1997-06-03 1998-06-03 还原α-氨基酮的方法 Expired - Fee Related CN1128135C (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP16200597 1997-06-03
JP162005/1997 1997-06-03
JP162005/97 1997-06-03
JP219287/1997 1997-07-29
JP21928797 1997-07-29
JP219287/97 1997-07-29

Publications (2)

Publication Number Publication Date
CN1228081A CN1228081A (zh) 1999-09-08
CN1128135C true CN1128135C (zh) 2003-11-19

Family

ID=26487946

Family Applications (1)

Application Number Title Priority Date Filing Date
CN98800734A Expired - Fee Related CN1128135C (zh) 1997-06-03 1998-06-03 还原α-氨基酮的方法

Country Status (10)

Country Link
US (1) US6255522B1 (enExample)
EP (1) EP0969000B1 (enExample)
KR (1) KR100517772B1 (enExample)
CN (1) CN1128135C (enExample)
AT (1) ATE229000T1 (enExample)
CA (1) CA2262966C (enExample)
DE (1) DE69809888T2 (enExample)
ES (1) ES2189169T3 (enExample)
IN (1) IN184319B (enExample)
WO (1) WO1998055452A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN184319B (enExample) 1997-06-03 2000-08-05 Kaneka Corp
JP4143787B2 (ja) * 1999-07-28 2008-09-03 味の素株式会社 α−アミノハロメチルケトン誘導体の製造方法
EP1346979A4 (en) * 2000-11-30 2005-11-09 Ajinomoto Kk PROCESS FOR THE PREPARATION OF N-PROTECTED AMINO ALCOHOLS AND N-PROTECTED AMINOEPOXIDES
DE60237584D1 (de) * 2001-03-02 2010-10-21 Daiichi Fine Chem Co Ltd Asymmetrische aminoketon-reduktase und nukleinsäure davon
WO2003104186A1 (ja) * 2002-06-11 2003-12-18 鐘淵化学工業株式会社 光学活性β−アミノアルコールの製造法
CN100436412C (zh) * 2004-07-06 2008-11-26 厦门大学 硼氢化物-酸还原体系还原氨基酮衍生物制备相应氨基醇的方法
CN102766074B (zh) * 2012-08-07 2014-05-07 江西东邦药业有限公司 抗艾滋病药物中间体的制备方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5523266B2 (enExample) * 1974-04-23 1980-06-21
JPS54154739A (en) * 1978-05-26 1979-12-06 Ono Pharmaceut Co Ltd Reducing agents
US4745204A (en) * 1986-06-05 1988-05-17 International Business Machines Corporation Process for producing aluminum alkoxide or aluminum aryloxide
JPS632935A (ja) * 1986-06-20 1988-01-07 Sumitomo Chem Co Ltd 光学活性アルコ−ル類の製造方法
JPH0723332B2 (ja) * 1987-05-29 1995-03-15 旭化成工業株式会社 1,3−ジクロル−2−プロパノ−ルの製造法
JP2804284B2 (ja) * 1988-03-23 1998-09-24 三共株式会社 4―アミノ―3―ヒドロキシカルボン酸類の立体選択的合成法
JP2847584B2 (ja) * 1991-06-21 1999-01-20 高砂香料工業株式会社 シクロヘキシル酪酸誘導体及びその製造法
JPH0525107A (ja) * 1991-07-19 1993-02-02 Nippon Kayaku Co Ltd 光学活性α−ヒドロキシ−βーアミノ酸エステルのラセミ化法
JPH07165678A (ja) * 1993-12-08 1995-06-27 Kanegafuchi Chem Ind Co Ltd ニトロオレフィン化合物
JPH0812629A (ja) * 1994-06-28 1996-01-16 Kanegafuchi Chem Ind Co Ltd 光学活性ジヒドロキシアミン誘導体の製造法及びその中間体
US5475138A (en) * 1994-07-07 1995-12-12 Pharm-Eco Laboratories Incorporated Method preparing amino acid-derived diaminopropanols
US5523463A (en) * 1994-09-23 1996-06-04 Hoffmann-La Roche Inc. Method of producing halogenated and alpha-aminoalchohols
JPH08143517A (ja) * 1994-11-18 1996-06-04 Nippon Kayaku Co Ltd 光学活性3−アミノ−1,2−ブタンジオール誘導体の製造法
JPH08198837A (ja) * 1995-01-25 1996-08-06 Mitsubishi Chem Corp 2−アミノ−1−アルカノール誘導体の製造方法
JP3855323B2 (ja) * 1995-11-17 2006-12-06 味の素株式会社 3−アミノ−2−オキソ−1−ハロゲノプロパン誘導体の製造方法
EP0827943B1 (en) 1996-01-29 2003-05-21 Kaneka Corporation Processes for the reduction of carbonyl compounds
CA2266473A1 (en) 1996-09-13 1998-03-19 Nippon Kayaku Kabushiki Kaisha A method for producing optically active erythro-3-amino-2-hydroxybutyric esters and acids thereof
IN184319B (enExample) 1997-06-03 2000-08-05 Kaneka Corp

Also Published As

Publication number Publication date
CA2262966C (en) 2007-09-18
DE69809888T2 (de) 2003-08-28
EP0969000A4 (en) 2000-07-12
CA2262966A1 (en) 1998-12-10
US6255522B1 (en) 2001-07-03
IN184319B (enExample) 2000-08-05
WO1998055452A1 (fr) 1998-12-10
KR20000068016A (ko) 2000-11-25
KR100517772B1 (ko) 2005-09-29
EP0969000B1 (en) 2002-12-04
ES2189169T3 (es) 2003-07-01
DE69809888D1 (de) 2003-01-16
CN1228081A (zh) 1999-09-08
ATE229000T1 (de) 2002-12-15
EP0969000A1 (en) 2000-01-05

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Granted publication date: 20031119

Termination date: 20140603