CN110845616A - 抗-egfr抗体及抗体药物偶联物 - Google Patents
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- CN110845616A CN110845616A CN201911118205.9A CN201911118205A CN110845616A CN 110845616 A CN110845616 A CN 110845616A CN 201911118205 A CN201911118205 A CN 201911118205A CN 110845616 A CN110845616 A CN 110845616A
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| NZ612909A (en) | 2011-01-10 | 2015-09-25 | Infinity Pharmaceuticals Inc | Processes for preparing isoquinolinones and solid forms of isoquinolinones |
| US8828998B2 (en) | 2012-06-25 | 2014-09-09 | Infinity Pharmaceuticals, Inc. | Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using PI3 kinase inhibitors |
| CA2890105C (en) | 2012-11-01 | 2023-03-21 | Infinity Pharmaceuticals, Inc. | Treatment of cancers using pi3 kinase isoform modulators |
| JP6592426B2 (ja) | 2013-03-15 | 2019-10-16 | バイオジェン・エムエイ・インコーポレイテッドBiogen MA Inc. | 無塩条件下で疎水性相互作用クロマトグラフィーを使用するタンパク質精製 |
| TW202330606A (zh) | 2014-03-21 | 2023-08-01 | 美商艾伯維有限公司 | 抗-egfr抗體及抗體藥物結合物 |
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| DE112014006656B4 (de) | 2014-05-14 | 2018-05-17 | Carsgen Therapeutics Limited | Nukleinsäure zur Kodierung eines chimären Antigen-Rezeptor-Proteins und T-Lymphozyt zur Expression eines chimären Antigen-Rezeptor-Proteins |
| CA2944085C (en) * | 2014-09-16 | 2018-04-10 | Ease Charm Limited | Anti-egfr antibody and uses of same |
| LT3292149T (lt) | 2015-05-04 | 2022-03-10 | Cytomx Therapeutics, Inc. | Aktyvinami antikūnai prieš cd71 ir jų naudojimo būdai |
| KR101776238B1 (ko) * | 2015-06-12 | 2017-09-12 | 사회복지법인 삼성생명공익재단 | 교모세포종 환자에서 이브루티닙 감수성과 관련된 유전자 및 그 용도 |
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| EP3368056B1 (en) * | 2016-01-26 | 2025-08-20 | Raghoottama Pandurangi | Compositions and methods for sensitizing low responsive tumors to cancer therapy |
| JP7081818B2 (ja) * | 2016-02-04 | 2022-06-07 | エーディーエス・セラピューティクス・エルエルシー | 疾患治療のための抗体-薬剤相乗作用技術 |
| CN109963870B (zh) | 2016-06-08 | 2023-07-28 | 艾伯维公司 | 抗b7-h3抗体和抗体药物偶联物 |
| EP3468616A1 (en) * | 2016-06-08 | 2019-04-17 | AbbVie Inc. | Anti-egfr antibody drug conjugates |
| BR112018075639A2 (pt) | 2016-06-08 | 2019-04-09 | Abbvie Inc. | conjugados de anticorpo fármaco anti-egfr |
| CN109563168A (zh) | 2016-06-08 | 2019-04-02 | 艾伯维公司 | 抗egfr抗体药物偶联物 |
| CN107522785B (zh) * | 2016-06-22 | 2020-05-08 | 北京大学 | 抗egfr突变体iii单克隆抗体、制备方法及其应用 |
| WO2017223422A1 (en) | 2016-06-24 | 2017-12-28 | Infinity Pharmaceuticals, Inc. | Combination therapies |
| CN108472371B (zh) * | 2016-07-05 | 2022-05-24 | 江苏恒瑞医药股份有限公司 | Egfr抗体-药物偶联物及其在医药上的应用 |
| KR20230114331A (ko) | 2016-09-14 | 2023-08-01 | 애브비 바이오테라퓨틱스 인크. | 항-pd-1 항체 및 이의 용도 |
| JP2020533269A (ja) * | 2016-12-14 | 2020-11-19 | デベロップメント センター フォー バイオテクノロジー | 抗体−薬物複合体およびその使用 |
| CA3068672A1 (en) | 2017-06-28 | 2019-01-03 | The Rockefeller University | Anti-mertk agonistic antibody-drug conjugates and uses thereof |
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