CN109476658B - 取代的5,6,7,8-四氢[1,2,4]三唑并[4,3-A]吡啶-3(2H)-酮和2,5,6,7-四氢-3H-吡咯并[2,1-c][1,2,4]三唑-3-酮及其用途 - Google Patents
取代的5,6,7,8-四氢[1,2,4]三唑并[4,3-A]吡啶-3(2H)-酮和2,5,6,7-四氢-3H-吡咯并[2,1-c][1,2,4]三唑-3-酮及其用途 Download PDFInfo
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- CN109476658B CN109476658B CN201780042622.2A CN201780042622A CN109476658B CN 109476658 B CN109476658 B CN 109476658B CN 201780042622 A CN201780042622 A CN 201780042622A CN 109476658 B CN109476658 B CN 109476658B
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| PCT/EP2017/060900 WO2017194459A1 (de) | 2016-05-09 | 2017-05-08 | Substituierte 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridin-3(2h)-one und 2,5,6,7-tetrahydro-3h-pyrrolo[2,1-c][1,2,4]triazol-3-one und ihre verwendung |
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| MX2007009796A (es) | 2007-08-14 | 2009-02-25 | Cell Therapy And Technology S | Gel conteniendo pirfenidona. |
| MX2011007675A (es) | 2011-07-19 | 2012-07-11 | Cell Therapy And Technology S A De C V | Procedimiento para la fabricacion de una composicion farmaceutica en forma de tabletas de liberacion prolongada conteniendo pirfenidona y su aplicacion en la regresion de la insuficiencia renal cronica, contractura capsular mamaria y fibrosis hepatica humanas. |
| MX346763B (es) | 2012-03-28 | 2017-03-31 | Cell Therapy And Tech S A De C V | Composición tópica semisólida conteniendo pirfenidona y dialil óxido de disulfuro modificado (odd-m) para eliminar o prevenir el acné. |
| MX356551B (es) | 2012-08-23 | 2018-06-04 | Grupo Medifarma S A De C V Star | Composición antiséptica, antiseborreica y exfoliante para eliminar o prevenir el acné. |
| EP3707141B1 (de) | 2017-11-07 | 2021-12-22 | Bayer Aktiengesellschaft | Substituierte 2,4-dihydro-3h-1,2,4-triazol-3-one und ihre verwendung |
| CN110950797A (zh) * | 2019-12-06 | 2020-04-03 | 丽水绿氟科技有限公司 | 一种2-三氟甲基-3-氟-4-吡啶甲酸及其衍生物的制备方法 |
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| WO2008144748A1 (en) | 2007-05-21 | 2008-11-27 | The Uab Research Foundation | Prolyl endopeptidase inhibitors for reducing or preventing neutrophilic inflammation |
| WO2011062864A2 (en) | 2009-11-17 | 2011-05-26 | Emory University | Inhibitors of nox enzymes and methods of use thereof |
| DE102010021637A1 (de) | 2010-05-26 | 2011-12-01 | Bayer Schering Pharma Aktiengesellschaft | Substituierte 5-Fluor-1H-Pyrazolopyridine und ihre Verwendung |
| US9216978B2 (en) | 2010-07-09 | 2015-12-22 | Bayer Intellectual Property Gmbh | Ring-fused pyrimidines and triazines and use thereof for the treatment and/or prophylaxis of cardiovascular diseases |
| DE102010040233A1 (de) | 2010-09-03 | 2012-03-08 | Bayer Schering Pharma Aktiengesellschaft | Bicyclische Aza-Heterocyclen und ihre Verwendung |
| DE102010043379A1 (de) | 2010-11-04 | 2012-05-10 | Bayer Schering Pharma Aktiengesellschaft | Substituierte 6-Fluor-1H-Pyrazolo[4,3-b]pyridine und ihre Verwendung |
| WO2012112363A1 (en) | 2011-02-14 | 2012-08-23 | Merck Sharp & Dohme Corp. | Cathepsin cysteine protease inhibitors |
| KR20130091464A (ko) * | 2012-02-08 | 2013-08-19 | 한미약품 주식회사 | 타이로신 카이네이즈 억제 활성을 갖는 트리아졸로피리딘 유도체 |
| US9624214B2 (en) | 2012-11-05 | 2017-04-18 | Bayer Pharma Aktiengesellschaft | Amino-substituted imidazo[1,2-a]pyridinecarboxamides and their use |
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