CN103642843B - 含有尿素类氮源的发酵培养基及其用于生产次级代谢产物、酶和重组蛋白的用途 - Google Patents
含有尿素类氮源的发酵培养基及其用于生产次级代谢产物、酶和重组蛋白的用途 Download PDFInfo
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- CN103642843B CN103642843B CN201310522914.XA CN201310522914A CN103642843B CN 103642843 B CN103642843 B CN 103642843B CN 201310522914 A CN201310522914 A CN 201310522914A CN 103642843 B CN103642843 B CN 103642843B
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- C12N1/38—Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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| RU2595380C2 (ru) * | 2008-02-06 | 2016-08-27 | Байокон Лимитид | Ферментационная среда для получения правастатина и способ получения правастатина |
| UA116217C2 (uk) | 2012-10-09 | 2018-02-26 | Санофі | Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону |
| MX362190B (es) | 2012-12-21 | 2019-01-08 | Sanofi Sa | Agonistas duales de glp1/gip o trigonales de glp1/gip/glucagon. |
| CN103911298B (zh) * | 2012-12-31 | 2016-08-10 | 中粮营养健康研究院有限公司 | 培养基组合物和培养基及对菌株进行活菌计数的方法 |
| WO2015086728A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Exendin-4 peptide analogues as dual glp-1/gip receptor agonists |
| WO2015086733A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Dual glp-1/glucagon receptor agonists |
| WO2015086729A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Dual glp-1/gip receptor agonists |
| TW201609796A (zh) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | 非醯化之艾塞那肽－４（ｅｘｅｎｄｉｎ－４）胜肽類似物 |
| TW201625670A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自ｅｘｅｎｄｉｎ－４之雙重ｇｌｐ－１／升糖素受體促效劑 |
| TW201625668A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 作為胜肽性雙重ｇｌｐ－１／昇糖素受體激動劑之艾塞那肽－４衍生物 |
| TW201625669A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自艾塞那肽－４（Ｅｘｅｎｄｉｎ－４）之肽類雙重ＧＬＰ－１／升糖素受體促效劑 |
| US9932381B2 (en) | 2014-06-18 | 2018-04-03 | Sanofi | Exendin-4 derivatives as selective glucagon receptor agonists |
| DE102014216863B4 (de) | 2014-08-25 | 2019-08-01 | Hansgrohe Se | Kopfbrause |
| AR105319A1 (es) | 2015-06-05 | 2017-09-27 | Sanofi Sa | Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico |
| TW201706291A (zh) | 2015-07-10 | 2017-02-16 | 賽諾菲公司 | 作為選擇性肽雙重ｇｌｐ－１／升糖素受體促效劑之新毒蜥外泌肽（ｅｘｅｎｄｉｎ－４）衍生物 |
| JP2018537075A (ja) | 2015-10-20 | 2018-12-20 | バックマン ラボラトリーズ インターナショナル，インコーポレイティド | 発酵による生物産物の製造のための酵母成長の増強方法、及び該方法のための栄養組成物 |
| AU2017208935A1 (en) * | 2016-01-23 | 2018-08-30 | Biocon Limited | Bio-analytical method for insulin analogues |
| CN107022591B (zh) * | 2017-05-11 | 2018-06-12 | 宜昌东阳光长江药业股份有限公司 | 一种提高胰岛素及其类似物前体表达的毕赤酵母发酵方法 |
| WO2018216978A1 (en) * | 2017-05-22 | 2018-11-29 | Cj Healthcare Corporation | Cell culture method at low temperature applicable to mass production of protein |
| CN107988292B (zh) * | 2018-01-18 | 2023-12-26 | 江苏江山聚源生物技术有限公司 | 提高重组人源胶原蛋白稳定性的发酵工艺 |
| CN111411049B (zh) * | 2020-04-15 | 2022-11-22 | 北京惠之衡生物科技有限公司 | 一种提高胰岛素前体表达的毕赤酵母的发酵培养基及发酵方法 |
| CN111996136A (zh) * | 2020-07-24 | 2020-11-27 | 北大方正集团有限公司 | 一种荧光假单孢杆菌发酵培养基、培养方法与应用 |
| CN114507609B (zh) * | 2020-12-22 | 2023-04-18 | 益海嘉里(连云港)生物科技有限公司 | 一种提高磷脂酶c蛋白产量的方法 |
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| WO2007005646A2 (en) * | 2005-07-01 | 2007-01-11 | The University Of Florida Research Foundation, Inc. | Recombinant host cells and media for ethanol production |
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| CN1017350B (zh) * | 1987-08-12 | 1992-07-08 | 中国石油化工总公司 | 微生物发酵正烷烃生产长链α·ω-二羧酸的方法 |
| US5830695A (en) * | 1995-11-29 | 1998-11-03 | Sankto Company, Limited | Actinomycete promoter |
| CN1328369C (zh) * | 1999-02-03 | 2007-07-25 | 药物研究所有限公司 | 培养物 |
| AU3910000A (en) | 1999-03-22 | 2000-10-09 | Zymogenetics Inc. | Improved methods for producing proteins in transformed (pichia) |
| RU2141531C1 (ru) * | 1999-05-26 | 1999-11-20 | Российское акционерное общество открытого типа "Биопрепарат" | Способ получения рекомбинантного инсулина человека |
| HUP9902352A1 (hu) * | 1999-07-12 | 2000-09-28 | Gyógyszerkutató Intézet Kft. | Eljárás pravasztatin mikrobiológiai előállítására |
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| KR100429925B1 (ko) * | 2001-12-28 | 2004-05-03 | 씨제이 주식회사 | 5'-크산틸산을 생산하는 미생물 |
| WO2003087381A1 (en) * | 2002-04-12 | 2003-10-23 | Mercian Corporation | Expression system of actinomycete-origin cytochrome p-450 in escherichia coli |
| RU2208637C1 (ru) * | 2002-04-16 | 2003-07-20 | Институт биоорганической химии им. М.М. Шемякина и Ю.А. Овчинникова РАН | Способ получения генно-инженерного инсулина человека |
| WO2004039996A1 (en) * | 2002-11-01 | 2004-05-13 | Cadila Healthcare Limited | Mthod for producing recombinant human interferon alpha 2b polypeptide in pichia pastoris |
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| RU2278870C2 (ru) * | 2004-08-30 | 2006-06-27 | Закрытое Акционерное Общество "Биокад" | Способ получения, выделения, очистки и стабилизации рекомбинантного гранулоцитарного колониестимулирующего фактора человека, пригодного для медицинского применения, и иммунобиологическое средство на его основе |
| WO2007102174A2 (en) * | 2006-03-06 | 2007-09-13 | Cadila Healthcare Limited | Process for preparing human g-csf |
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| RU2595380C2 (ru) * | 2008-02-06 | 2016-08-27 | Байокон Лимитид | Ферментационная среда для получения правастатина и способ получения правастатина |
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| WO2007005646A2 (en) * | 2005-07-01 | 2007-01-11 | The University Of Florida Research Foundation, Inc. | Recombinant host cells and media for ethanol production |
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