CN102754668A - Novel Chinese herbal medicine compound disinfectant solution - Google Patents

Abstract

The invention relates to a novel Chinese herbal medicine compound disinfectant solution which is suitable to be used in households, medical and health institutions, restaurants, hotels, banks, schools, public canteens, small and medium-sized food processing plants, offices, and farms. The solution can be used in disinfections of skin wounds, common object surfaces, and public place environments. The disinfectant solution is formulated by using various pure-natural Chinese herbal medicines extracts and biologically active components. Therefore, the product is advantaged in mild property, high stability, no toxic or side effect, no environmental pollution, and easy washing. The solution is green and environment-friendly, and has relatively high inhibiting and killing effects against various common pathogens. With the solution, skin wound infections caused by various pathogens can be effectively prevented, disinfecting and skin protecting effects can be provided, and thorough disinfection can be carried out upon object surfaces and public place environments. With the solution, no hidden danger is left. The product is advantaged in fragrant smell, long sterilizing effect, no corrosion, and no irritation. The product is a real novel multifunctional composite disinfectant solution.

Description

The biological compound disinfectant of novel Chinese herbal medicine

Technical field the present invention relates to the biological compound disinfectant of a kind of novel Chinese herbal medicine, and its effective sterilization component adopts smilax, the tuber of multiflower knotweed, the bighead atractylodes rhizome; Tulip, honeysuckle, cloves, mother chrysanthemum; Rattlebush, lysozyme, bios and double-chain quaternary ammonium salt are prepared from through special process.Being adapted at family, medical and health organization, restaurant, hotel, bank, school, canteen, middle-size and small-size food processing factory, office and plant uses; Can be used for the sterilization of skin wound sterilization, general body surface and public place environment.Because what adopt is that the extract and the bioactive ingredients compatibility of pure natural Chinese herbal medicine forms, so the character of this product is gentle, the environmental protection no side effects; Pathogenic bacteria such as salmonella, Escherichia coli, staphylococcus aureus, Pseudomonas aeruginosa all there are stronger inhibition and killing action; Not only can effectively prevent the infection of various pathogenic bacteria to skin wound, can also hidden danger not be stayed in body surface and assanation thorough disinfection, be real Multifunction composite disinfectant.The present invention well merges China's the quintessence of Chinese culture and biologic product, for synergy R&D direction and thinking biological, plant disinfectant have been opened new voyage.

Background technology is since compatriots experience SARS, bird flu; People pay attention to the application of sterile products more; Its scope of application not only is confined to Compulsory sterilizing places such as medical and health organization; But having expanded to many public places, food processing factory, animal-breeding field etc., the use for disinfectant in the daily family is also more and more paid attention to.Existing disinfectant generally is chemicals; Mostly its active ingredient is aldehydes, alcohols, peroxide, halogen, acids etc., to the effect that object has bleaching and corrodes, is subject to the influence of organic matter and acid-base value; Some disinfectant is prone to decompose; Instability has certain excitant and toxicity to the people, and difficult flushing.Along with the extensive use of chemosterilant, problems have been exposed gradually, the drug resistance that disinfectant is produced such as microorganism, the problem of environmental pollution that disinfectant causes etc.Because many toxic and side effects of chemosterilant, people begin to pay close attention to the antibacterial action of Chinese medicine.Research shows, plant can produce some antibacterial materials and resist invasion and attack for the invasion and attack of the invasion, particularly microorganism that keep self avoiding extraneous.The antibacterial material of plant is exactly a kind of natural protection material concerning plant itself.People such as Ji Lilian discover that smilax decocting liquid has the antimicrobial spectrum of stronger antibacterial activity and broad, has certain value as the antibacterium resource.People such as Ma Wanxia discover that the bacteriostasis rate of the bighead atractylodes rhizome all has killing action in various degree more than 83.1% to Escherichia coli, staphylococcus aureus, hay bacillus.Bonus equality people finds that Chinese medicines such as cloves, mother chrysanthemum, honeysuckle have tangible fungistatic effect.The extract of a lot of edible Chinese herbal medicines has the antibiotic and sterilizing effect; But when using as disinfectant separately, effect is barely satisfactory, and therefore seldom seeing on the market with the Chinese herbal medicine is main thimerosal; People hope to have a kind of can be in efficient sterilizing; It is strong to have stability, no side effects, and the thimerosal of environmental protection comes out.The present invention rationally is mixed multiple Chinese herbal medicine with restraining and sterilizing bacteria effect; Add bioactive ingredients simultaneously and work in coordination with the performance sterilization; Purpose is to provide a kind of can overcome the not enough composite multifunction biological antiseptic liquid of existing procucts; Become the green product that nontoxic, non-stimulated, no burn into has no side effect, have efficient sterilizing, disinfecting skin-care, good stability, be convenient to flushing, advantage such as free from environmental pollution.

Summary of the invention main points of the present invention have been to select multiple Chinese herbal medicine with bactericidal effect, rationally are mixed, through the Chinese medicine extract that grinds, leaches, filters, distills, blends, operation such as adsorption stripping is processed purifying.Be mixed with bioactivator is collaborative again, finally process the biological compound disinfectant of a kind of novel Chinese herbal medicine.

The prescription that the present invention selects is (component and percentage by weight % thereof) as follows: smilax 2.0-3.5, tuber of multiflower knotweed 1.2-3.6, bighead atractylodes rhizome 1.0-3.0; Tulip 1.5-3.5, honeysuckle 2.3-4.5, cloves 1.0-4.3; Mother chrysanthemum 2.5-4.6, rattlebush 1.2-2.6, lysozyme 0.5-2.0; Bios 3.5-6.0, double-chain quaternary ammonium salt 2.1-4.2, deionized water adds to 100.

Main sterilization antipathogenic composition as this product; We have extracted several kinds of edible Chinese herbal medicines with restraining and sterilizing bacteria effectiveness, and wherein the smilax and the bighead atractylodes rhizome all have bacteriostasis in various degree to typhoid bacillus, paratyphoid bacillus A, shigella flexneri, Escherichia coli, Pseudomonas aeruginosa etc.; Tuber of multiflower knotweed decocting liquid all has inhibitory action in various degree to staphylococcus aureus, staphylococcus albus, shigella flexneri, sonne bacillus, diphtheria bacillus, beta hemolysis streptococcus, Nai Shi catarrh bacterium etc.; The active ingredient of honeysuckle is the chlorogenic acid compound; Has broad-spectrum antiviral; Antibacterial effect, it all has inhibitory action in various degree to multiple pathogenic bacteria, like staphylococcus aureus, hemolytic streptococcus, shigella dysenteriae, comma bacillus etc.; To some dermatophyte, certain inhibitory action is also arranged like rust budlet spore tinea bacterium, star nocardia; Tulip glucosides in the tulip is hydrolyzed into the unsaturated lactone aglucon behind the contact pathogenic microorganisms, its oxidation product toxicity is big, directly pathogenic microbe killing; Cloves also has stronger inhibition and killing action to pathogenic bacteria such as salmonella, Escherichia coli, staphylococcus aureus, Pseudomonas aeruginosas; Mother chrysanthemum can reduce tiring of staphylococcus aureus hemolysin, the inhibitory action certain to being formed with of staphylococcus aureus plasma-coagulase; Monocrotaline in the rattlebush is stronger to antimicrbial powers such as staphylococcus aureus, hemolytic streptococcus, diphtheria bacilluss.Several kinds of Chinese medicines rationally are mixed more than inciting somebody to action, and can bring into play the concurrent disinfection bactericidal action.

Bios is a pure natural nonhazardous material; Gathering polysaccharide, chitosan shitosan by biological complex enzyme, alginic acid lives plain the composition; Complex enzyme in this component, gather polysaccharide, the chitosan shitosan plain very high activity that all has of living; Can suppress and intervene the enzyme system and the splitting function of bacterium, virus, make the breeding function forfeiture of bacterium, virus, reach sterilizing function.

Lysozyme itself is a kind of protein for acting on the cytohydrolist of peptide glycan in the bacteria cell wall specially, and security performance is high, and Gram-positive bacteria is had stronger bactericidal action.It mainly through-acetylmuramic acid in the destruction cell wall and β-1,4 glycosidic bond between the N-n acetylglucosamine n, makes the insoluble glutinous polysaccharide of cell wall resolve into the solubility glycopeptide, causes the effusion of cell wall rupture content and makes bacterolysis.Lysozyme also can directly combine with electronegative virus protein, forms double salt with DNA, RNA, apoprotein, makes virally inactivated.Therefore, this enzyme has antibiotic, anti-inflammatory, effect such as antiviral.

Double-chain quaternary ammonium salt is a cationic surfactant, and is positively charged in water, can be adsorbed on the microorganism surface and form micelle; And progressively infiltrate cytoplasmic lipoid layer and protein layer, thus change the after birth permeability, cellular content is exosmosed; Cause microbial death, coagulated protein makes enzyme and structural proteins sex change simultaneously; The metabolism of destroy microorganisms, thus microorganism is killed.

The preparation method of product of the present invention is:

(1) with smilax, the tuber of multiflower knotweed, the bighead atractylodes rhizome, tulip; Honeysuckle, cloves, mother chrysanthemum is after rattlebush eight flavor Chinese medicines mix in proportion; Pulverize powderedly,, constantly add the solvent distilled water, make it penetrate medicinal material the herbal powder percolator of packing into; Flow out leachate from top to bottom from the percolator bottom, the control flow velocity replenishes novel solvent at any time on powder in the diacolation process, medicinal material active ingredient is fully leached till;

(2) Chinese medicine extract that leaches is left standstill 30min after, add in the double filter screen formula Chinese medicine multipotency extractor, utilize large-area ring-like filter screen of tank body and tank body leakage fluid dram, it is quick and complete to obtain discharge opeing, the Chinese medicine extract of good filtration effect;

(3) Chinese medicine extract is further added thermal distillation, obtain the Chinese medicine extract of purifying more;

(4) bios, double-chain quaternary ammonium salt, lysozyme and purifying is good Chinese medicine extract is blent by proportioning, and deionized water to 100 adds in the retort mixing and stirring;

(5) charcoal absorption is discolored;

(6) detect qualified after, leave standstill packing.

The present invention compares with existing disinfectant has following advantage: (1) sterilization effect is remarkable, and is particularly remarkable to staphylococcus aureus and hemolytic streptococcus; (2) active ingredient stable performance keeps long-acting sterilizing time; (3) working concentration is low, uses after can being diluted to 100 times; (4) pure-natural biological preparation, nontoxic, non-stimulated, non-corrosiveness, smell delicate fragrance; (5) character is gentle, can be used for the sterilization of human body skin, and is easy to flushing; (6) scope of application is wide, is suitable for the sterilization of general body surface and public place environment; (7) can carry, convenient and practical; (8) technology is simple, and cost is low.

Embodiment is done further detailed description below in conjunction with embodiment to the present invention:

Be configured according to listed data of following table (percentage by weight %) and affiliated step thereof:

Prescription one:

Prescription two:

Prescription three:

Prescription four:

Claims (2)

1. the present invention relates to the biological compound disinfectant of a kind of novel Chinese herbal medicine, it is characterized in that having following prescription (component and percentage by weight % thereof): smilax 2.0-3.5, tuber of multiflower knotweed 1.2-3.6, bighead atractylodes rhizome 1.0-3.0; Tulip 1.5-3.5, honeysuckle 2.3-4.5, cloves 1.0-4.3; Mother chrysanthemum 2.5-4.6, rattlebush 1.2-2.6, lysozyme 0.5-2.0; Bios 3.5-6.0, double-chain quaternary ammonium salt 2.1-4.2, deionized water adds to 100.

2. the preparation method of the biological compound disinfectant of the said novel Chinese herbal medicine of a claim 1 is characterized in that having following steps:

(1) with smilax, the tuber of multiflower knotweed, the bighead atractylodes rhizome, tulip; Honeysuckle, cloves, mother chrysanthemum is after rattlebush eight flavor Chinese medicines mix in proportion; Pulverize powderedly,, constantly add the solvent distilled water, make it penetrate medicinal material the herbal powder percolator of packing into; Flow out leachate from top to bottom from the percolator bottom, the control flow velocity replenishes novel solvent at any time on powder in the diacolation process, medicinal material active ingredient is fully leached till;

(2) Chinese medicine extract that leaches is left standstill 30min after, add in the double filter screen formula Chinese medicine multipotency extractor, utilize large-area ring-like filter screen of tank body and tank body leakage fluid dram, it is quick and complete to obtain discharge opeing, the Chinese medicine extract of good filtration effect;

(3) Chinese medicine extract is further added thermal distillation, obtain the Chinese medicine extract of purifying more;

(4) bios, double-chain quaternary ammonium salt, lysozyme and purifying is good Chinese medicine extract is blent by proportioning, and deionized water to 100 adds in the retort mixing and stirring;

(5) charcoal absorption is discolored;

(6) detect qualified after, leave standstill packing.