CN102090994B - Sterilization and disinfection skin protection sanitizer - Google Patents
Sterilization and disinfection skin protection sanitizer Download PDFInfo
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- CN102090994B CN102090994B CN 201010276052 CN201010276052A CN102090994B CN 102090994 B CN102090994 B CN 102090994B CN 201010276052 CN201010276052 CN 201010276052 CN 201010276052 A CN201010276052 A CN 201010276052A CN 102090994 B CN102090994 B CN 102090994B
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- silver
- antibacterial
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- 238000004659 sterilization and disinfection Methods 0.000 title description 21
- 230000001954 sterilising effect Effects 0.000 claims description 24
- 239000007788 liquid Substances 0.000 claims description 7
- 238000004140 cleaning Methods 0.000 claims description 6
- 230000000844 anti-bacterial effect Effects 0.000 abstract description 25
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 abstract description 15
- 239000004332 silver Substances 0.000 abstract description 12
- 229910052709 silver Inorganic materials 0.000 abstract description 12
- 238000005406 washing Methods 0.000 abstract description 10
- 241000894006 Bacteria Species 0.000 abstract description 8
- 230000000249 desinfective effect Effects 0.000 abstract description 8
- 238000002360 preparation method Methods 0.000 abstract description 8
- 241000700605 Viruses Species 0.000 abstract description 7
- 241000233866 Fungi Species 0.000 abstract description 6
- 241000270295 Serpentes Species 0.000 abstract description 6
- 244000005700 microbiome Species 0.000 abstract description 6
- 238000004519 manufacturing process Methods 0.000 abstract description 5
- 230000001580 bacterial effect Effects 0.000 abstract description 4
- 239000012847 fine chemical Substances 0.000 abstract description 2
- 238000003889 chemical engineering Methods 0.000 abstract 1
- 239000000047 product Substances 0.000 description 23
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 21
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 20
- 230000000694 effects Effects 0.000 description 17
- 239000003242 anti bacterial agent Substances 0.000 description 16
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 16
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 15
- 238000003756 stirring Methods 0.000 description 12
- 239000004408 titanium dioxide Substances 0.000 description 10
- DBAKFASWICGISY-BTJKTKAUSA-N Chlorpheniramine maleate Chemical compound OC(=O)\C=C/C(O)=O.C=1C=CC=NC=1C(CCN(C)C)C1=CC=C(Cl)C=C1 DBAKFASWICGISY-BTJKTKAUSA-N 0.000 description 8
- 230000003115 biocidal effect Effects 0.000 description 8
- 229960003291 chlorphenamine Drugs 0.000 description 8
- 238000011161 development Methods 0.000 description 8
- 230000018109 developmental process Effects 0.000 description 8
- OSVXSBDYLRYLIG-UHFFFAOYSA-N dioxidochlorine(.) Chemical compound O=Cl=O OSVXSBDYLRYLIG-UHFFFAOYSA-N 0.000 description 8
- 239000004166 Lanolin Substances 0.000 description 7
- USIUVYZYUHIAEV-UHFFFAOYSA-N diphenyl ether Chemical compound C=1C=CC=CC=1OC1=CC=CC=C1 USIUVYZYUHIAEV-UHFFFAOYSA-N 0.000 description 7
- 229940039717 lanolin Drugs 0.000 description 7
- 235000019388 lanolin Nutrition 0.000 description 7
- 239000002994 raw material Substances 0.000 description 7
- 239000000126 substance Substances 0.000 description 7
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 6
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 6
- 208000015181 infectious disease Diseases 0.000 description 5
- 230000002147 killing effect Effects 0.000 description 5
- 229940051841 polyoxyethylene ether Drugs 0.000 description 5
- 229920000056 polyoxyethylene ether Polymers 0.000 description 5
- 239000004155 Chlorine dioxide Substances 0.000 description 4
- 239000004354 Hydroxyethyl cellulose Substances 0.000 description 4
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 description 4
- 235000019398 chlorine dioxide Nutrition 0.000 description 4
- 239000008367 deionised water Substances 0.000 description 4
- 229910021641 deionized water Inorganic materials 0.000 description 4
- SYELZBGXAIXKHU-UHFFFAOYSA-N dodecyldimethylamine N-oxide Chemical compound CCCCCCCCCCCC[N+](C)(C)[O-] SYELZBGXAIXKHU-UHFFFAOYSA-N 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 230000001804 emulsifying effect Effects 0.000 description 4
- 239000012467 final product Substances 0.000 description 4
- 229940071826 hydroxyethyl cellulose Drugs 0.000 description 4
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 4
- 238000002156 mixing Methods 0.000 description 4
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 description 4
- HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 description 3
- DHHFDKNIEVKVKS-FMOSSLLZSA-N Betanin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC(C(=C1)O)=CC(C[C@H]2C([O-])=O)=C1[N+]2=C\C=C\1C=C(C(O)=O)N[C@H](C(O)=O)C/1 DHHFDKNIEVKVKS-FMOSSLLZSA-N 0.000 description 3
- DHHFDKNIEVKVKS-MVUYWVKGSA-N Betanin Natural products O=C(O)[C@@H]1NC(C(=O)O)=C/C(=C\C=[N+]/2\[C@@H](C(=O)[O-])Cc3c\2cc(O)c(O[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O2)c3)/C1 DHHFDKNIEVKVKS-MVUYWVKGSA-N 0.000 description 3
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- 229920001214 Polysorbate 60 Polymers 0.000 description 3
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 3
- 239000004141 Sodium laurylsulphate Substances 0.000 description 3
- HVUMOYIDDBPOLL-XWVZOOPGSA-N Sorbitan monostearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O HVUMOYIDDBPOLL-XWVZOOPGSA-N 0.000 description 3
- 229910010413 TiO 2 Inorganic materials 0.000 description 3
- 208000027418 Wounds and injury Diseases 0.000 description 3
- 229940088710 antibiotic agent Drugs 0.000 description 3
- 239000001654 beetroot red Substances 0.000 description 3
- 235000012677 beetroot red Nutrition 0.000 description 3
- JBIROUFYLSSYDX-UHFFFAOYSA-M benzododecinium chloride Chemical compound [Cl-].CCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1 JBIROUFYLSSYDX-UHFFFAOYSA-M 0.000 description 3
- 235000002185 betanin Nutrition 0.000 description 3
- 229910000019 calcium carbonate Inorganic materials 0.000 description 3
- 239000001768 carboxy methyl cellulose Substances 0.000 description 3
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 3
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 239000012153 distilled water Substances 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 244000052769 pathogen Species 0.000 description 3
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 3
- QEKATQBVVAZOAY-UHFFFAOYSA-M sodium;4-propan-2-ylbenzenesulfonate Chemical compound [Na+].CC(C)C1=CC=C(S([O-])(=O)=O)C=C1 QEKATQBVVAZOAY-UHFFFAOYSA-M 0.000 description 3
- 230000000087 stabilizing effect Effects 0.000 description 3
- 206010011409 Cross infection Diseases 0.000 description 2
- 241000725303 Human immunodeficiency virus Species 0.000 description 2
- 206010029803 Nosocomial infection Diseases 0.000 description 2
- FOIXSVOLVBLSDH-UHFFFAOYSA-N Silver ion Chemical compound [Ag+] FOIXSVOLVBLSDH-UHFFFAOYSA-N 0.000 description 2
- 206010052428 Wound Diseases 0.000 description 2
- 230000000172 allergic effect Effects 0.000 description 2
- 230000002421 anti-septic effect Effects 0.000 description 2
- 208000010668 atopic eczema Diseases 0.000 description 2
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- 238000005202 decontamination Methods 0.000 description 2
- 230000003588 decontaminative effect Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
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- 230000007918 pathogenicity Effects 0.000 description 2
- 238000004321 preservation Methods 0.000 description 2
- 239000008213 purified water Substances 0.000 description 2
- 239000000344 soap Substances 0.000 description 2
- 239000004094 surface-active agent Substances 0.000 description 2
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- 241000588724 Escherichia coli Species 0.000 description 1
- 206010017533 Fungal infection Diseases 0.000 description 1
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- 241000700721 Hepatitis B virus Species 0.000 description 1
- 102000011782 Keratins Human genes 0.000 description 1
- 108010076876 Keratins Proteins 0.000 description 1
- 201000009906 Meningitis Diseases 0.000 description 1
- 241000204031 Mycoplasma Species 0.000 description 1
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- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 1
- 201000004681 Psoriasis Diseases 0.000 description 1
- 241000711798 Rabies lyssavirus Species 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 206010040047 Sepsis Diseases 0.000 description 1
- 229920002385 Sodium hyaluronate Polymers 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- VBIIFPGSPJYLRR-UHFFFAOYSA-M Stearyltrimethylammonium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCCCC[N+](C)(C)C VBIIFPGSPJYLRR-UHFFFAOYSA-M 0.000 description 1
- 206010065954 Stubbornness Diseases 0.000 description 1
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- 230000009471 action Effects 0.000 description 1
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- 210000001557 animal structure Anatomy 0.000 description 1
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- 239000000043 antiallergic agent Substances 0.000 description 1
- 229940121375 antifungal agent Drugs 0.000 description 1
- 206010003246 arthritis Diseases 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 239000003093 cationic surfactant Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 229910001919 chlorite Inorganic materials 0.000 description 1
- 229910052619 chlorite group Inorganic materials 0.000 description 1
- QBWCMBCROVPCKQ-UHFFFAOYSA-N chlorous acid Chemical compound OCl=O QBWCMBCROVPCKQ-UHFFFAOYSA-N 0.000 description 1
- 239000012459 cleaning agent Substances 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
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- 206010013023 diphtheria Diseases 0.000 description 1
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- 230000001900 immune effect Effects 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
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- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 229910052740 iodine Inorganic materials 0.000 description 1
- 239000011630 iodine Substances 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
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- 239000000314 lubricant Substances 0.000 description 1
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- 239000001301 oxygen Substances 0.000 description 1
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- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 230000001699 photocatalysis Effects 0.000 description 1
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- 244000144977 poultry Species 0.000 description 1
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- 201000003068 rheumatic fever Diseases 0.000 description 1
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- 150000003378 silver Chemical class 0.000 description 1
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- SXHLENDCVBIJFO-UHFFFAOYSA-M sodium;2-[2-(2-dodecoxyethoxy)ethoxy]ethyl sulfate Chemical compound [Na+].CCCCCCCCCCCCOCCOCCOCCOS([O-])(=O)=O SXHLENDCVBIJFO-UHFFFAOYSA-M 0.000 description 1
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- Agricultural Chemicals And Associated Chemicals (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention relates to an antibacterial disinfecting snake oil skin-protection hand-washing solution, belonging to technical field of production and preparation of small products in fine chemical engineering. Silver can kill microorganisms such as bacterial virus fungus and the like, and also can kill 650 types of morbigenous biological bacteria and effective control stubborn bacterial strains and flora; so far, the research finds that no bacteria microorganism cannot be killed by silver within 6 minutes in laboratories; and the use amount is low, and the antibacterial action time is long, therefore, the broad spectrum high-effect nano-silver antibacterial disinfecting snake oil skin-protection hand-washing solution is completely safe, reliable, and safe to use.
Description
Technical field:
Broad spectrum high-effect nano-silver antibacterial disinfecting snake oil skin-protection hand-washing solution of the present invention is to belong to fine chemistry industry miscellaneous goods to produce the preparation technique field.
Background technology:
Fine chemical product be a kind of production scale little, wide in variety, update soon, surcharge is high, profit is large and need a series products of new and high technology.The development of accelerating fine chemistry industry is the development trend of current chemical industry, our country of emerging now particularly, emphasis with development of chemical industry turns to fine chemistry industry in succession, great transformation is occuring in the industrial structure of chemical industry, and this will produce far-reaching influence to the development prospect of China's chemical industry undoubtedly.The at present development of China's fine chemistry industry is subject to the close attention of all trades and professions, and the now task of top priority is as early as possible industry restructuring, the paces of accelerating development.
Summary of the invention:
Fine chemistry industry is emerging field most active in the current chemical industry, and it presents fast-developing situation, and China attaches great importance to the development of fine chemistry industry, the strategic emphasis of fine chemistry industry as industrial development.At present fine chemistry industry has become in China's chemical industry an important individual branches and new growth engines.For this reason, the present invention has carried out new innovation aspect nano-silver antibacterial disinfecting snake oil skin-protection hand-washing solution.The microorganisms such as silver can killing bacteria, virus, fungus, but harmless to the human normal cell, as a kind of natural antibacterial agent from soil, the effect of silver is very extensive, deserves to be called the second immunologic barrier outside the born immune system of human body.Silver ion all has good effect to treatment gastritis, disease disease, parasitic infection, psoriasis, eye, ear and oral cavity infection, yeast infection, and it both can take orally, again can external.The appearance of silver is the miracle of modern medicine, a kind of antibiotic can only kill 6 kinds of pathogenic organisms bacterium, and silver can kill 650 kinds, and can effectively control obstinate bacterial strain flora, the silver of minute quantity just can be eliminated a large amount of pathogenic organisms bodies, under lab, not yet find up to now do not have any microorganism in 6min, not killed by silver.Silver effect aspect the infectious disease such as treatment septicemia, rheumatic fever, gonorrhea, arthritis, diphtheria, meningitis is remarkable, all has effect and the ability of highly significant for treatment burn and other wounds.
All antibiotic are standing the heavy negative of antibacterial infection at present, especially in hospital, the antimicrbial power that it is found that antibacterial is more and more stronger, sometimes resist antibiotic by changing bacterial structure originally, make antibacterial more and more be difficult to remove, and use the larger antibiotic of toxicity or use the medicament of high concentration, its toxic and side effects has brought extremely serious threat for again people's health.The satisfactory to both parties plan of unique safety is silver, and silver all can produce the existence of nearly all antibacterial, virus and extracellular virus known today and suppress and killing action, simultaneously because concentration is lower, harmless, and can not produce any Drug resistance again.Nanometer silver is the broad spectrum high-effect antibacterial, consumption is little, and the antibacterial action effect is lasting, and the multiple noxious bacteria that comprises antibacterial, fungus, infusorian, mycoplasma is had good inhibition and killing action, the Resistant strain flora is had equal killing power, and effectively antibiotic rate is up to 99.9%.More than can effectively dispel the corrupt stink that produces of various Organic substances, can effectively shield Contamination of Electromagnetic Wave, isolation also produces effect to ultraviolet.
Exist the invisible microorganism of a large amount of naked eyes in the human living environment, comprise various antibacterials, fungus and virus, they are (suitable temperature and humidity and sufficient oxygen divide) rapidly breeding under certain conditions with just can becoming geometrical progression, show as the phenomenon such as infection, suppuration of the corruption of article, rotten, mouldy and wound, until bring fatal disease to the mankind, therefore society is caused very large harm, use the sterilization of broad spectrum high-effect nanometer silver series antibacterial agent, sterilization, antibacterial, sterilization, mildew-resistant, anticorrosion." AT " nano antibacterial agent is a kind of novel inorganic antiseptic, has TiO
2The photocatalysis antibacterial function and the sterilization composite effect of silver ion.TiO
2Be present modal photocatalyst-type anti-biotic agent, antibacterial ability is strong, has a broad antifungal spectrum, and this material toxicity is low, and is non-stimulated to skin to the person poultry safety, has and namely imitate antibacterial effect.If the effect of silver-series antibacterial agent performance antibacterial effect needs about 24h, and TiO
2The antibacterial action performance only needs about 1h, this " AT " antibacterial has been produced by the Chenzhou City Jingui Nonferrous Metal Co., Ltd and has been put on market, detect through national authority testing agency, to the pathogenic bacteria killing rate of escherichia coli, these two kinds serious threat human healths in life of staphylococcus aureus up to 99.99%.Become the antibiotic and sterilizing disinfecting skin care hand-washing liquid with this as preparation of raw material, sterilization, sterilization are had very significantly effect.
The present invention is further described below in conjunction with examples of implementation:
Embodiment one: powerful antibiotic and sterilizing disinfecting snake oil skin-protection hand-washing
| Raw material | Proportioning (weight portion) |
| Acetylated lanolin | 1.0 |
| Glycerol | 5.0 |
| Adeps Serpentis | 3.0 |
| Chlorphenamine | 0.5 |
[0009]
| Silver-carrying nano (AT) titanium dioxide anti-bacterial agent | 0.5 |
| Dodecyl dimethyl benzyl ammonium chloride | 3.0 |
| Dimethyl dodecyl amine oxide | 25.0 |
| Fatty alcohol-polyoxyethylene ether | 3.0 |
| Hydroxyethyl-cellulose | 1.0 |
| Essence | 0.2 |
| Citric acid | 0.3 |
| Purified water | Add to 100 |
Preparation method:
(1) acetylated lanolin, glycerol, Adeps Serpentis are mixed and heated to 80 ℃ and get the A group;
(2) dodecyl dimethyl benzyl ammonium chloride, dimethyl dodecyl amine oxide, silver-carrying nano (AT) titanium dioxide anti-bacterial agent, fatty alcohol-polyoxyethylene ether are heated to 80 ℃ and get the B group;
(3) two groups of A, B are put into respectively the mulser stirring and emulsifying, add simultaneously hydroxyethyl-cellulose, chlorphenamine and the emulsifying of water restir and naturally cool to 40 ℃ after good, add again essence, the citric acid mixing gets final product.
Illustrate:
Dodecyl dimethyl benzyl ammonium chloride is a kind of cationic surfactant, have good decontamination cleaning function and dirt cohesion, has broad spectrum high-effect sterilization sterilization Disinfection Effect with silver-carrying nano (AT) antibacterial agents, and can kill all pathogenic organisms bacterium, the non-stimulated and injury to human body.
Product is used:
This product sterilization, sterilization, sterilization, decontamination, skin protection, frost-cracking-preventing, tender skin.
Embodiment two: the sterilizing skin care hand cleaning liquid
| Raw material | Proportioning (weight portion) |
| 2,4,4 '-three chloro-2 '-dihydroxy diphenyl ether | 1.0 |
| Hyaluronate sodium | 0.1 |
| Sodium lauryl sulphate | 4.0 |
[0020]
| Betanin | 2.5 |
| The p-isopropyl benzene sulfonic acid sodium salt | 5.0 |
| Isopropyl alcohol | 6.0 |
| 1,2-PD | 10.0 |
| Silver-carrying nano (AT) titanium dioxide anti-bacterial agent | 0.5 |
| Citric acid | 8.0 |
| Monoethanolamine | 5.0 |
| Essence | 0.2 |
| Deionized water | Add to 100 |
Preparation method:
(1) 1d immerses hyaluronate sodium in the distilled water in advance, makes its dissolving for subsequent use;
(2) with 2,4,4 '-three chloro-2 '-dihydroxy diphenyl ether is dissolved in the 1,2-PD for subsequent use;
(3) betanin is dissolved in the distilled water, rear interpolation sodium lauryl sulphate stirs, join after the stirring and dissolving in the solution (2), stir, add distilled water and silver-carrying nano (AT) titanium dioxide anti-bacterial agent, add again p-isopropyl benzene sulfonic acid sodium salt, citric acid, be stirred to evenly, under continuous stirring state, slowly add monoethanolamine and transfer to PH to 4.5～5, add again and dissolve fully and the sodium hyaluronate solution through filtering, transfer to PH to 5.5 with monoethanolamine again after stirring evenly, fill gets final product.
Illustrate:
(1) 2,4,4 '-three chloro-2 '-dihydroxy diphenyl ether is halogenated diphenyl ether, it is the high-efficiency broad spectrum antibacterial, it has and kills widely and inhibitory action pathogenicity Gram-positive and negative bacterium, fungus, yeast and the virus (such as hepatitis A, hepatitis B virus, rabies virus, HIV (human immunodeficiency virus) etc.) that causes infection, pathogenicity skin bacteria effect to stubbornness is especially outstanding, effective equally to antibiotic resistant bacteria and non-antibiotic fastbacteria, and with skin good affinity is arranged, under low concentration, can reach sterilization effect;
(2) sodium lauryl sulphate, sodium lauryl tri(oxyethyl) sulfate, p-isopropyl benzene sulfonic acid sodium salt, betanin etc. are surfactant;
(3) ethanol, 1,2-PD, isopropyl alcohol are low mass molecule alcohol;
(4) hyaluronate sodium can extract from the animal organ or produce by microbial fermentation, and it is the natural moisture preserving lubricant, and skin is had moisture-keeping function;
(5) essence can be selected as required.
Product is used:
This product is mainly used in the hand disinfection of hospital, pharmaceuticals industry and other occasions.Can reduce the incidence rate of nosocomial infection in the hospital; Prevent microorganism pollution to product in medicine, Cosmetic Manufacture and other industry.
Product attribute:
This product technique convenient operation, prescription is reasonable, broad-spectrum antiseptic, result of use is remarkable, nonirritant and toxic and side effects, and certain skin-protecting function is arranged, life-time service is safe and reliable.
Embodiment three: the sterilizing snake oil skin-protection hand-washing
| Raw material | Proportioning (weight portion) |
| Acetylated lanolin | 1.0 |
| Glycerol | 1.0 |
| Adeps Serpentis | 0.5 |
| Chlorphenamine | 0.5 |
| Silver-carrying nano (AT) titanium dioxide anti-bacterial agent | 0.5 |
| 1227 antibacterial | 1.5 |
| Dimethyl dodecyl amine oxide | 20.0 |
| Fatty alcohol-polyoxyethylene ether | 3.0 |
| Hydroxyethyl-cellulose | 1.0 |
| Essence | 0.2 |
| Citric acid | 0.3 |
| Purified water | Add to 100 |
Preparation method:
(1) acetylated lanolin, glycerol, Adeps Serpentis are added pure water, in agitated kettle, fully stir, be heated to 65～75 ℃, make solution;
(2) dimethyl dodecyl amine oxide and fatty alcohol-polyoxyethylene ether are added pure water; In agitated kettle, fully stir, be heated to 65～75 ℃, make solution;
(3) solution (1) and solution (2) are put into the emulsifying pot together, add simultaneously hydroxyethyl-cellulose, pure water, after emulsifying is good, add silver-carrying nano (AT) titanium dioxide anti-bacterial agent, chlorphenamine, add again 1227 antibacterial, mixing and stirring, naturally cool to uniform temperature after, add essence, citric acid, mixing and stirring is regulated PH to 7, gets product.
Product is used:
This product is mainly used in the cleaning and disinfection sterilization of staff, has simultaneously skin care effect.
Product attribute:
This product raw material is easy to get, and technique is simple, suitability for scale production; Prescription is reasonable, strong detergency, and character is gentle, and is non-stimulated to skin, uses safety.
Embodiment four: sterilizing Adeps Serpentis skin-protecting cleaning agent for hands
| Raw material | Proportioning (weight portion) |
| Acetylated lanolin | 2.0 |
| Adeps Serpentis | 0.5 |
| Chlorphenamine | 0.3 |
| Tween-60 | 8.0 |
| Arlacel-60 | 8.0 |
| Carboxymethyl cellulose | 1.0 |
| Stabilizing chlorine dioxide | 1.5 |
| ZnO | 1.0 |
| Silver-carrying nano (AT) titanium dioxide anti-bacterial agent | 0.5 |
| Calcium carbonate | 40.0 |
| Deionized water | Add to 100 |
Preparation method:
(1) acetylated lanolin, Adeps Serpentis, Tween-60, Arlacel-60 are put into reactor and heat, start simultaneously blender, make it to mix and stir, heat preservation for standby use during to 75 ℃, this is oil phase;
(2) deionized water, chlorphenamine, silver-carrying nano (AT) titanium dioxide anti-bacterial agent are heated, heat preservation for standby use during to 75 ℃, this is water;
(3) water (2) is slowly poured in the oil phase (), the blender in the oil phase should accelerate to rotate, and rotating speed can be at 600r/min;
(4) after above-mentioned biphase mixing, carboxymethyl cellulose is added in the reactor, can reduce to 80r/min this moment with rotating speed; when temperature is down to below 50 ℃; stabilizing chlorine dioxide, calcium carbonate can be added in the reactor, and do stirring at low speed, approximately can shut down discharging behind the 30min.
Illustrate:
(1) acetylated lanolin, Adeps Serpentis are skin protectant, and be good with the skin affinity, can prevent that skin keratin is aging;
(2) Tween-60, Arlacel-60 are surfactant, and both intersolubilities are fabulous, and be comfortable with rear skin smooth;
(3) carboxymethyl cellulose is excipient, in the situation that there is activating agent composite, the dirt after washing one's hands is very easily removed, and can not be attached on the container of washing one's hands again, and should expect cheap;
(4) silver-carrying nano (AT) titanium dioxide anti-bacterial agent has the strong disinfecting disinfective action, and the sterilizing scope is wide, and is effective;
(5) chlorphenamine is anti-allergic agent, causes the various allergic stimulated of skin for anti-foreign preteins;
(6) stabilizing chlorine dioxide is sanitizer, is the chlorine dioxide with high purity gas that utilizes the acidified effect of chlorite to occur, and it is stabilized in forms in the inertia solution that to contain effective constituent concentration be disinfectant more than 2%;
(7) calcium carbonate is the abrasivus of washing one's hands.
Product is used:
This product is particularly suitable as the special product that the industrial and mineral labor protection is washed one's hands, and is widely used in cleaning both hands after the work, has simultaneously sterilization, skin care effect.
Product attribute:
This product function admirable organically combines several functions, and result of use is remarkable; Good stability, long shelf-life is easy to carry about with one; Nontoxic, nonirritant, safe and reliable.
Embodiment five: the operation sterilizing handwashing liquid
| Raw material | Proportioning (weight portion) |
| Fatty alcohol-polyoxyethylene ether | 3.0 |
| Alkylphenol polyoxyethylene | 2.0 |
| Alkylolamides | 2.0 |
| Octadecyl trimethyl ammonium chloride | 2.0 |
| Citric acid | 1.0 |
| Essence | 0.5 |
| Glycerol | 1.0 |
| Adeps Serpentis | 0.5 |
| Chlorphenamine | 0.5 |
| Silver-carrying nano (AT) titanium dioxide anti-bacterial agent | 0.8 |
| Polyvinyl Pyrrolidone-Iodine | 30.0 |
| Deionized water | Add to 100 |
Preparation method:
Get final product each component is soluble in water.
Product is used:
This product is mainly used in the front medical worker's of surgical operation hand disinfection, also is applicable to the food processing producer.
Pre-operation sterilization uses this liquid soap 10ml, and brush hands 1min soaks 4min, can kill all antibacterials, fungus, virus, mycotic spore.Daily handwashing disinfection only needs this liquid soap of 3ml to get final product.
Product attribute:
This product is cheap, and production technology is simple; Prescription is reasonable, and bactericidal effect is remarkable, and reliability is high and easy to use, and the cross infection that can stop performs the operation brings is also shortened disinfecting time; Nonirritant, without allergic phenomena, injured skin not.
Claims (1)
1. a sterilizing skin care hand cleaning liquid is characterized in that: be comprised of following prescription
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201010276052 CN102090994B (en) | 2010-09-08 | 2010-09-08 | Sterilization and disinfection skin protection sanitizer |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201010276052 CN102090994B (en) | 2010-09-08 | 2010-09-08 | Sterilization and disinfection skin protection sanitizer |
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| Publication Number | Publication Date |
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| CN102090994A CN102090994A (en) | 2011-06-15 |
| CN102090994B true CN102090994B (en) | 2013-03-06 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN 201010276052 Expired - Fee Related CN102090994B (en) | 2010-09-08 | 2010-09-08 | Sterilization and disinfection skin protection sanitizer |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103006464A (en) * | 2011-09-20 | 2013-04-03 | 天津博克尼科技发展有限公司 | Iodine-containing disinfection hand cleaner without water |
| CN102302418B (en) * | 2011-09-21 | 2013-01-23 | 韩褆 | Water-saving type multifunctional hand-washing disinfectant |
| CN102860923B (en) * | 2012-09-21 | 2013-11-27 | 华绣科技有限公司 | Nano-silver antibacterial liquid soap and preparation method thereof |
| CN106726752A (en) * | 2016-12-15 | 2017-05-31 | 苏州市启扬商贸有限公司 | A kind of anhydrous washing hand liquid |
| CN108467805A (en) * | 2018-03-12 | 2018-08-31 | 合肥华盖生物科技有限公司 | A kind of kitchen tools greasy dirt detergent and preparation method thereof |
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| CN101612101A (en) * | 2008-06-27 | 2009-12-30 | 李栋 | A kind of preparation method of nanometer silver ion cosmetic |
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