CN107737070A - Sterilization, skin care hand cleaning liquid - Google Patents
Sterilization, skin care hand cleaning liquid Download PDFInfo
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- CN107737070A CN107737070A CN201711140943.4A CN201711140943A CN107737070A CN 107737070 A CN107737070 A CN 107737070A CN 201711140943 A CN201711140943 A CN 201711140943A CN 107737070 A CN107737070 A CN 107737070A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Gerontology & Geriatric Medicine (AREA)
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Abstract
The invention discloses one kind sterilization, skin care hand cleaning liquid and preparation method thereof.The hand cleanser includes the component of following parts by weight:15 25 parts of lemon grass extract, 10 20 parts of Flos Lonicerae extractive solution, 5 10 parts of soapberry extract, 0.1 0.5 parts of hyaluronic acid, edible 25 35 parts of olive oil, 20 40 parts of diet of coconut oil, 13 parts of sodium hydroxide, 100 150 parts of purified water.Present invention sterilization, skin care hand cleaning liquid fragrance fragrance are pleasant, natural, stability is good, with multi-efficiencies such as deep clean skin, anti-inflammation, skin-moisturizing, skin, whitening antioxidation, removing dampness to stop itchin, the growth of skin surface bacterium can effectively be suppressed, it is and safe and non-toxic, it is gently non-stimulated to skin, it is adapted to various people to use.
Description
Technical field
The invention belongs to commodity processing technique field, and in particular to one kind sterilization, skin care hand cleaning liquid and preparation method thereof.
Background technology
Hand cleanser is because its is easy to use, is easy to rinse as the indispensable cleaning supplies of huge numbers of families.At present on the market
Hand cleanser mainly possess cleaning, sterilizing function, wherein major antibacterial composition is triclosan and Trichlorocarbanilide is
It is main.Triclosan is a kind of broad spectrum antimicrobial agent, is widely used in the daily chemical products such as soap, toothpaste;Trichlorocarbanilide
It is a kind of efficient, broad spectrum antimicrobial agent, it has to multiple-microorganisms such as gram-positive bacteria, Gram-negative bacteria, fungi, saccharomycete
There is efficient inhibitory or killing effect.However, U.S.'s food and Drug Administration announce that this two kinds of compositions are equal in September, 2016
In the presence of the risk for destroying human immune system.In addition, hand cleanser function on the market is relatively simple, more with cleaning, fungistatic effect
Based on, it is difficult to take into account the protection to hand skin.Therefore, exploitation safety, take into account cleaning, sterilization, skin care multiple action it is pure
Natural hand cleanser is very urgent.
Lemon grass (Cymbopogon Citratus) is also known as lemon grass (Cymbopogon citratus), lemon-grass, belongs to grass family lemongrass plant (scientific name:
Cymbopogon), Mexico, Honduras are originated in, China Hainan, Yunnan, Fujian Province introduce a fine variety.Contain in the stem and leaf of lemongrass
Abundant volatile oil, there is calmness, antianxiety, anti-spasm, antibiotic and sterilizing and the medical work(such as aid digestion by the essential oil of lemongrass extraction
Effect.Lemon-grass contains substantial amounts of vitamin C, has Glycerin, contributes to the effect of skin maintenance, and lemon-grass also has regulation
Fat secretion acts on, and can be used as cosmetology good merchantable brand, be beneficial to oily skin and hair quality, can be added to the water cleaning skin, promotes
Blood circulation.Therefore, the daily chemical product prepared using lemon grass extract and other plants essential oils has multi-efficiency, applies
Prospect is very wide.
The content of the invention
It is an object of the invention to provide a kind of sterilization, skin care with multi-efficiencies such as mosquito repellent, antipruritic, skin-moisturizing, skins to wash one's hands
Liquid and preparation method thereof.
The technical solution adopted by the present invention is as follows:
One kind sterilization, skin care hand cleaning liquid, include the component of following parts by weight:Lemon grass extract 15-25 parts, honeysuckle
Extract solution 10-20 parts, soapberry extract 5-10 parts, hyaluronic acid 0.1-0.5 parts, edible olive oil 25-35 parts, edible coconut
Oily 20-40 parts, sodium hydroxide 1-3 parts, purified water 100-150 parts.
Above-described sterilization, skin care hand cleaning liquid, most preferably preferably include the component of following parts by weight:Lemon grass extract
20 parts, 15 parts of Flos Lonicerae extractive solution, 8 parts of soapberry extract, 0.3 part of hyaluronic acid, edible 30 parts of olive oil, diet of coconut oil
30 parts, 2 parts of sodium hydroxide, 120 parts of purified water.
Above-described sterilization, the preparation method of skin care hand cleaning liquid, comprise the following steps:
S1:Component is weighed by following parts by weight:Lemon grass extract 15-25 parts, Flos Lonicerae extractive solution 10-20 parts, nothing
Suffer from seed extract 5-10 parts, hyaluronic acid 0.1-0.5 parts, edible olive oil 25-35 parts, diet of coconut oil 20-40 parts, hydroxide
Sodium 1-3 parts, purified water 100-150 parts;
S2:Load weighted sodium hydroxide is dissolved in purified water, stirring makes to be completely dissolved, and adds lemon grass extraction
Thing, Flos Lonicerae extractive solution, soapberry extract, hyaluronic acid, are stirred to dissolve, and obtain solution A;
S3:Edible olive oil, diet of coconut oil are mixed, water proof is heated to 40 DEG C, obtains solution B;
S4:Solution A, B are mixed, stirs to fully saponified, through dispensing after the assay was approved, produces.
The beneficial effects of the invention are as follows:
1. there is lemon grass extract Glycerin, whitening antioxidation, removing dampness to stop itchin, town to disappear only in inventive formulation
Inflammation, go prickly heat, antimycotic and other effects;Flos Lonicerae extractive solution has the effect such as clearing heat and detoxicating, bactericidal antiphlogistic;Soapberry extract has
The effect such as have anti-inflammation, anti-oxidant, dirt-removing power strong so that present invention sterilization, skin care hand cleaning liquid fragrance fragrance it is pleasant,
Naturally, stability is good, there is the multiple work(such as deep clean skin, anti-inflammation, skin-moisturizing, skin, whitening antioxidation, removing dampness to stop itchin
Effect, can effectively suppress the growth of skin surface bacterium.
2. present invention sterilization, raw materials used skin care hand cleaning liquid are pure natural substance, safe and non-toxic, gently stingless to skin
Swash, can be long-term use of, it also is adapted for various people's use.
Embodiment
With reference to specific embodiment, the invention will be further described, but does not limit the scope of the invention and apply
Scope:
First, sterilization, the preparation method of skin care hand cleaning liquid
Embodiment 1
It is a kind of be used for sterilize, the preparation method of skin care hand cleaning liquid, comprise the following steps:
S1:Component is weighed by following parts by weight:Lemon grass extract 2.5kg, Flos Lonicerae extractive solution 2.0kg, soapberry
Extract 1.0kg, hyaluronic acid 0.05kg, edible olive oil 3.5kg, diet of coconut oil 4.0kg, sodium hydroxide 0.3kg, purifying
Water 15kg;
S2:Load weighted sodium hydroxide is dissolved in purified water, stirring makes to be completely dissolved, and adds lemon grass extraction
Thing, Flos Lonicerae extractive solution, soapberry extract, hyaluronic acid, are stirred to dissolve, and obtain solution A;
S3:Edible olive oil, diet of coconut oil are mixed, water proof is heated to 40 DEG C, obtains solution B;
S4:Solution A, B are mixed, stirs to fully saponified, through dispensing after the assay was approved, produces.
Embodiment 2
It is a kind of be used for sterilize, the preparation method of skin care hand cleaning liquid, comprise the following steps:
S1:Component is weighed by following parts by weight:Lemon grass extract 1.5kg, Flos Lonicerae extractive solution 1.0kg, soapberry
Extract 0.5kg, hyaluronic acid 0.01kg, edible olive oil 2.5kg, diet of coconut oil 2.0kg, sodium hydroxide 0.1kg, purifying
Water 10kg;
S2:Load weighted sodium hydroxide is dissolved in purified water, stirring makes to be completely dissolved, and adds lemon grass extraction
Thing, Flos Lonicerae extractive solution, soapberry extract, hyaluronic acid, are stirred to dissolve, and obtain solution A;
S3:Edible olive oil, diet of coconut oil are mixed, water proof is heated to 40 DEG C, obtains solution B;
S4:Solution A, B are mixed, stirs to fully saponified, through dispensing after the assay was approved, produces.
Embodiment 3
It is a kind of be used for sterilize, the preparation method of skin care hand cleaning liquid, comprise the following steps:
S1:Component is weighed by following parts by weight:Lemon grass extract 2.0kg, Flos Lonicerae extractive solution 1.5kg, soapberry
Extract 0.8kg, hyaluronic acid 0.03kg, edible olive oil 3.0kg, diet of coconut oil 3.0kg, sodium hydroxide 0.2kg, purifying
Water 12kg;
S2:Load weighted sodium hydroxide is dissolved in purified water, stirring makes to be completely dissolved, and adds lemon grass extraction
Thing, Flos Lonicerae extractive solution, soapberry extract, hyaluronic acid, are stirred to dissolve, and obtain solution A;
S3:Edible olive oil, diet of coconut oil are mixed, water proof is heated to 40 DEG C, obtains solution B;
S4:Solution A, B are mixed, stirs to fully saponified, through dispensing after the assay was approved, produces.
2nd, bacteriostatic test
1. material
1.1 test strain
Staphylococcus aureus [CMCC (B) 26003], pseudomonas aeruginosa [CMCC (B) 10104], Candida albicans.
1.2 test specimen
Test sample:1-3 of embodiment of the present invention sample, accurately weigh during experiment be dissolved in right amount in axenic purification water it is (dense eventually
Spend 100mg/ml);
Positive control:
Commercially available disinfection hand cleanser, 100mg/ml is diluted to axenic purification water during experiment;
Negative control:Sterile saline.
1.3 culture medium
Pancreas junket soya peptone Agar Plating, pancreas junket soya peptone fluid nutrient medium, Sabouraud dextrose fluid nutrient medium, sand
Family name's glucose agar medium.
2. method
The preparation of 2.1 bacterium solutions
Staphylococcus aureus, P. aeruginosa strain are inoculated in pancreas junket soya peptone fluid nutrient medium, 30 DEG C of cultures
24h, it is 2 × 10 that the bacterium solution of gained is carried out into gradient dilution to concentration7CFU/mL, it is standby;Candida albicans is inoculated in Sharpe
Dextrose broth, 25 DEG C of culture 48h, it is 2 × 10 that the bacterium solution of gained is carried out into gradient dilution to concentration6CFU/mL, it is standby
With
The preparation of 2.2 test panels
First toward pouring into 20mL or so plating mediums in sterilized flat board, horizontal rest solidification, inoculation 0.1mL bacterium solutions,
After sterile L-type glass rod coating uniformly, send and cultivate 15min under corresponding test strain requirement cultivation temperature, it is standby.
2.3 inhibition zone methods (K-B methods) are tested
Dried after circle filter paper is sterilized, soak 1h in the sample solution of each concentration under 1.2, then use aseptic nipper
Gripping drug containing filter paper is attached to the surface of plating medium containing bacterium prepared under 2.2, presses lightly on, makes the scraps of paper close with culture medium
Cut-grafting is touched, and each culture dish uniformly places 5 filter papers, 4 DEG C of prediffusion 2h, then puts 35 DEG C of constant incubator cultures respectively
24h, its bacteriostatic diameter (in units of mm) is determined by crossing method, results averaged, refers to table 1.
The bacteriostatic test result table of table 1
Packet | Staphylococcus aureus (mm) | Pseudomonas aeruginosa (mm) | Candida albicans (mm) |
Embodiment 1 | 18.5 | 18.8 | 17.1 |
Embodiment 2 | 17.2 | 17.5 | 16.2 |
Embodiment 3 | 17.6 | 18.2 | 16.7 |
Positive control | 10.4 | 11.1 | 9.0 |
Negative control | - | - | - |
As can be seen from Table 1,1-3 of embodiment of the present invention samples and positive control are false single to staphylococcus aureus, verdigris
Born of the same parents bacterium has inhibitory action, and embodiment 1-3 samples are stronger than positive control to the inhibitory action of 2 kinds of bacterium, illustrate that the present invention has
Good bacteriostasis.
2nd, application test
Present invention sterilization, skin care hand cleaning liquid, were once tried out in 144 volunteers.By the above-mentioned 3 kinds of implementations prepared
Example sample, is given following 144 volunteers and tried out, while compareed with commercially available disinfection hand cleanser respectively.As a result the present invention is implemented
The cleaning of example 1-3 products, insulation soothing effect are superior to compare, and it is clear well to illustrate that present invention sterilization, skin care hand cleaning liquid have
Clean, skin effect.
The specific implementation of the invention is not to be limited to these illustrations for above content, is led for technology belonging to the present invention
For the those of ordinary skill in domain, without departing from the inventive concept of the premise, some simple deduction or replace can also be made,
The scope of patent protection that the present invention is determined by the claims submitted should be all considered as belonging to.
Claims (3)
1. one kind sterilization, skin care hand cleaning liquid, it is characterised in that include the component of following parts by weight:Lemon grass extract 15-25
Part, Flos Lonicerae extractive solution 10-20 parts, soapberry extract 5-10 parts, hyaluronic acid 0.1-0.5 parts, edible olive oil 25-35
Part, diet of coconut oil 20-40 parts, sodium hydroxide 1-3 parts, purified water 100-150 parts.
2. sterilization according to claim 1, skin care hand cleaning liquid, it is characterised in that include the component of following parts by weight:Lemon
20 parts of lemongrass extract, 15 parts of Flos Lonicerae extractive solution, 8 parts of soapberry extract, 0.3 part of hyaluronic acid, edible 30 parts of olive oil,
30 parts of diet of coconut oil, 2 parts of sodium hydroxide, 120 parts of purified water.
3. a kind of sterilization according to claim 1 or 2, the preparation method of skin care hand cleaning liquid, it is characterised in that including following
Step:
S1:Component is weighed by following parts by weight:Lemon grass extract 15-25 parts, Flos Lonicerae extractive solution 10-20 parts, soapberry
Extract 5-10 parts, hyaluronic acid 0.1-0.5 parts, edible olive oil 25-35 parts, diet of coconut oil 20-40 parts, sodium hydroxide 1-
3 parts, purified water 100-150 parts;
S2:Load weighted sodium hydroxide is dissolved in purified water, stirring makes to be completely dissolved, and adds lemon grass extract, gold
Honeysuckle flower extract solution, soapberry extract, hyaluronic acid, are stirred to dissolve, and obtain solution A;
S3:Edible olive oil, diet of coconut oil are mixed, water proof is heated to 40 DEG C, obtains solution B;
S4:Solution A, B are mixed, stirs to fully saponified, through dispensing after the assay was approved, produces.
Priority Applications (1)
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CN201711140943.4A CN107737070A (en) | 2017-11-16 | 2017-11-16 | Sterilization, skin care hand cleaning liquid |
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CN201711140943.4A CN107737070A (en) | 2017-11-16 | 2017-11-16 | Sterilization, skin care hand cleaning liquid |
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ID=61234803
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108210391A (en) * | 2018-03-22 | 2018-06-29 | 南京工业大学 | Skin-care and bacteriostatic hand sanitizer and preparation method thereof |
CN111228177A (en) * | 2020-03-04 | 2020-06-05 | 广州清淞泉生物科技有限公司 | Bacteriostatic easy-to-wash foam hand sanitizer and preparation method thereof |
CN111789796A (en) * | 2020-04-28 | 2020-10-20 | 广东分子态生物股份有限公司 | Disinfectant with liposome-encapsulated bactericidal component and preparation method thereof |
CN111789795A (en) * | 2020-04-28 | 2020-10-20 | 广东分子态生物股份有限公司 | Hand sanitizer with liposome-encapsulated bactericidal component and preparation method thereof |
CN112210445A (en) * | 2020-09-30 | 2021-01-12 | 山东华熙海御生物医药有限公司 | Hyaluronic acid cleaning solution and preparation method thereof |
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Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108210391A (en) * | 2018-03-22 | 2018-06-29 | 南京工业大学 | Skin-care and bacteriostatic hand sanitizer and preparation method thereof |
CN111228177A (en) * | 2020-03-04 | 2020-06-05 | 广州清淞泉生物科技有限公司 | Bacteriostatic easy-to-wash foam hand sanitizer and preparation method thereof |
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CN111789796A (en) * | 2020-04-28 | 2020-10-20 | 广东分子态生物股份有限公司 | Disinfectant with liposome-encapsulated bactericidal component and preparation method thereof |
CN111789795A (en) * | 2020-04-28 | 2020-10-20 | 广东分子态生物股份有限公司 | Hand sanitizer with liposome-encapsulated bactericidal component and preparation method thereof |
CN112210445A (en) * | 2020-09-30 | 2021-01-12 | 山东华熙海御生物医药有限公司 | Hyaluronic acid cleaning solution and preparation method thereof |
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