CN102824290B - Liquid soap - Google Patents
Liquid soap Download PDFInfo
- Publication number
- CN102824290B CN102824290B CN2012103527582A CN201210352758A CN102824290B CN 102824290 B CN102824290 B CN 102824290B CN 2012103527582 A CN2012103527582 A CN 2012103527582A CN 201210352758 A CN201210352758 A CN 201210352758A CN 102824290 B CN102824290 B CN 102824290B
- Authority
- CN
- China
- Prior art keywords
- decoct
- liquid soap
- parts
- herba potentillae
- potentillae discoloris
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- 239000007788 liquid Substances 0.000 title claims abstract description 28
- 239000000344 soap Substances 0.000 title claims abstract description 16
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims abstract description 8
- 235000019333 sodium laurylsulphate Nutrition 0.000 claims abstract description 8
- 238000002360 preparation method Methods 0.000 claims abstract description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 15
- 239000012567 medical material Substances 0.000 claims description 10
- 235000019388 lanolin Nutrition 0.000 abstract description 4
- 230000000844 anti-bacterial effect Effects 0.000 abstract description 3
- 241001571466 Potentilla discolor Species 0.000 abstract 1
- 244000234281 Tamarix gallica Species 0.000 abstract 1
- 235000014265 Tamarix gallica Nutrition 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 18
- 230000001580 bacterial effect Effects 0.000 description 13
- 239000003153 chemical reaction reagent Substances 0.000 description 10
- 229940079593 drug Drugs 0.000 description 10
- 238000010790 dilution Methods 0.000 description 9
- 239000012895 dilution Substances 0.000 description 9
- 241000222122 Candida albicans Species 0.000 description 5
- 241000191967 Staphylococcus aureus Species 0.000 description 5
- 230000002401 inhibitory effect Effects 0.000 description 5
- 235000015097 nutrients Nutrition 0.000 description 5
- 241000894006 Bacteria Species 0.000 description 4
- 241000588724 Escherichia coli Species 0.000 description 4
- 229940095731 candida albicans Drugs 0.000 description 4
- 239000001963 growth medium Substances 0.000 description 4
- 239000002609 medium Substances 0.000 description 4
- 241000194017 Streptococcus Species 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 230000002949 hemolytic effect Effects 0.000 description 3
- 244000005700 microbiome Species 0.000 description 3
- 239000006159 Sabouraud's agar Substances 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 241000193990 Streptococcus sp. 'group B' Species 0.000 description 2
- 244000309466 calf Species 0.000 description 2
- 239000003085 diluting agent Substances 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 235000013372 meat Nutrition 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 210000002966 serum Anatomy 0.000 description 2
- 235000014347 soups Nutrition 0.000 description 2
- 241000894007 species Species 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 229920001817 Agar Polymers 0.000 description 1
- 238000009631 Broth culture Methods 0.000 description 1
- ZKQDCIXGCQPQNV-UHFFFAOYSA-N Calcium hypochlorite Chemical compound [Ca+2].Cl[O-].Cl[O-] ZKQDCIXGCQPQNV-UHFFFAOYSA-N 0.000 description 1
- 206010007134 Candida infections Diseases 0.000 description 1
- 241000628997 Flos Species 0.000 description 1
- 241000238631 Hexapoda Species 0.000 description 1
- 241001494479 Pecora Species 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000007844 bleaching agent Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 201000003984 candidiasis Diseases 0.000 description 1
- 239000003518 caustics Substances 0.000 description 1
- 239000012459 cleaning agent Substances 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 238000005202 decontamination Methods 0.000 description 1
- 230000003588 decontaminative effect Effects 0.000 description 1
- 230000001408 fungistatic effect Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 1
- 239000006916 nutrient agar Substances 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
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- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention provides a liquid soap, which is characterized by comprising 40-60 parts of sodium lauryl sulfate, 6-10 parts of wool grease, 2-4 parts of potentilla discolor and 2-4 parts of tamarix chinensis. A corresponding preparation method is adopted. The liquid soap has a very good antibacterial effect.
Description
Technical field
The present invention relates to the cosmetics technical field, be specifically related to a kind of liquid soap.
Background technology
Along with people's living standard improves day by day, also more and more higher to the prescription of liquid soap.Though the liquid soap of selling on the market is various, a lot of products have added some harmful materials more or less: as bleaching powder, hydrargyrum, cleaning agent, caustic etc.People there is also a desire for more excellent liquid soap, particularly utilize Chinese medicine to prepare liquid soap.
Summary of the invention
Goal of the invention:, the object of the present invention is to provide a kind of liquid soap and preparation method thereof in order to address the above problem.
Technical scheme: the objective of the invention is to realize by following scheme:
A kind of liquid soap contains sodium lauryl sulfate 40-60 part, lanoline 6-10 part, Herba Potentillae Discoloris 2-4 part, Cacumen Tamaricis 2-4 part.
The preparation method of aforesaid liquid soap, preparation process is: get Herba Potentillae Discoloris, Cacumen Tamaricis, decoct with water twice, the 8-12 that adds for the first time water and be medical material weight doubly measures, and decocts 1-2h, the 6-10 that adds for the second time water and be medical material weight doubly measures, decoct the 1-2h collecting decoction, be concentrated into 10 times of amounts of Herba Potentillae Discoloris, Cacumen Tamaricis gross weight, add sodium lauryl sulfate, lanoline, the 70-80 ℃ of left and right sides is melt and dissolved, promptly.
Beneficial effect:
Fungistatic effect of the present invention is good, is the influence result of the test of the present invention to staphylococcus aureus below
1 test material
(1) medicine and reagent
Be subjected to reagent: prepare liquid soap by preparation embodiment 3 methods, be the present invention: specification: 2g crude drug/g, lot number: 20120503; Sodium chloride: Shanghai hundred million chemical reagent company limiteies of a specified duration, lot number: 00060120.Nutrient broth medium: CAS Shanghai Insect Bio Technological Development Co., Ltd., lot number: 110516.Nutrient agar: microorganism reagent factory of Jiangsu Prov. Disease Preventing and Controlling Center, lot number: 110016.Improvement Martin culture medium: sky, Hangzhou and microorganism reagent company limited, lot number: 100831.Improvement Martin culture medium: Beijing three medicine scientific and technological development companies, lot number: 111213; Sabouraud's agar: Beijing Luqiao Technology Co., Ltd. of China Inst. of Quarantine Inspection Sciences, lot number: 1007153; Calf serum, Hangzhou Sijiqing Biological Engineering Material Co., Ltd., lot number: 100508; Take off fine sheep blood, available from Jiangning county epidemic prevention station, lot number: 120312
(2) bacterial strain
Reference culture: staphylococcus aureus (ATCC25923), escherichia coli (441490), beta hemolytic streptococcus (32210) are provided by disease control and prevention center, Jiangsu Province microorganism reagent factory; Candida albicans (98100) is provided by the institute for drug control, Jiangsu Province.
(3) instrument and equipment
Electronic balance, Beijing Sai Duolisi balance company limited is produced; The full-automatic high-pressure autoclave, Japanese SANYO;
Superclean bench, Suzhou Decontamination Equipment Plant; The biochemical incubator of SHP-80, the gloomy reliable Instr Ltd. that tests in Shanghai
2 experimental techniques
(1) antibacterial culturing
Get reference culture: staphylococcus aureus (ATCC25923), escherichia coli (441490), beta hemolytic streptococcus (32210) bacterial strain a little, be inoculated in respectively in the nutrient broth medium, cultivate 18h for 37 ℃.(adding 20% calf serum in the group B streptococcus broth bouillon) gets each bacterial strain nutrient broth culture that 18h cultivates, and does 10 with nutrient broth
-3Dilution is used for experiment.Extracting waste candidiasis bacterial strain a little, be inoculated in the improvement Martin culture medium, cultivate 24h for 35 ℃.Get the Candida albicans culture that 24h cultivates, with improvement Martin culture medium 10
-3Dilution is used for experiment.
(2) doubling dilution (test tube method)
Get 11 in sterilization test tube, the 1st pipe adds nutrient broth fluid medium 1.6ml, all the other every pipe 1ml, get respectively and added in first pipe by reagent diluent 0.4ml, get 1ml to the 2 pipes behind the mixing, dilution successively, the 10th pipe sucking-off 1ml discards, and the 11st pipe does not add medicinal liquid in contrast.Every pipe adds dilution bacterium liquid 0.1ml, cultivates 24h for 37 ℃.Take out the bacterial growth situation of observing.As the drug liquid tube muddiness, promptly represent bacterial growth, there is not bacteriostasis for the reagent thing; Represent then that as drug liquid tube is limpid bacterial growth is suppressed, the medicinal liquid of the greatest dilution that it can bacteria growing inhibiting is the minimal inhibitory concentration (MIC) of this medicine.Limpid medicinal liquid meat soup is respectively managed transferred species bouillon agar flat board, cultivate 24h and observe, the minimum drug level that does not still have bacterial growth is the bacteriocidal concentration of this medicine.
Get 11 in sterilization test tube, the 1st pipe adds improvement Martin fluid medium 1.6ml, all the other every pipe 1ml, get respectively and added in first pipe by reagent diluent 0.4ml, get 1ml to the 2 pipes behind the mixing, dilution successively, the 10th pipe sucking-off 1ml discards, and the 11st pipe does not add medicinal liquid in contrast.Every pipe adds dilution bacterium liquid 0.1ml, cultivates 24h for 35 ℃, takes out the bacterial growth situation of observing.As the drug liquid tube muddiness, promptly represent bacterial growth, there is not bacteriostasis for the reagent thing; Represent then that as drug liquid tube is limpid bacterial growth is suppressed, the medicinal liquid of the greatest dilution that it can bacteria growing inhibiting is the minimal inhibitory concentration (MIC) of this medicine.Limpid medicinal liquid meat soup is respectively managed transferred species sabouraud's agar flat board, cultivate 24h and observe, the minimum drug level that does not still have bacterial growth is the bacteriocidal concentration of this medicine.
3 results
Experimental result shows: liquid soap of the present invention is to reference culture: staphylococcus aureus (ATCC25923), escherichia coli (441490), beta hemolytic streptococcus (32210), Candida albicans all have stronger bacteriostasis, and MIC press the calculating of crude drug amount at 0.05g～0.2g/g().See Table 1.
Table 1 antibacterial activity in vitro of the present invention (n=2)
| Bacterial strain | Minimum inhibitory concentration (MIC) (the g crude drug/g) |
| Staphylococcus aureus (standard) | 0.1 |
| Escherichia coli (standard) | 0.1 |
| Group B streptococcus (standard) | 0.05 |
| Candida albicans | 0.2 |
3.1.4 conclusion
Liquid soap of the present invention has good bacteriostasis.
The specific embodiment
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention only limits to following example, all technology that realizes based on foregoing of the present invention all belong to scope of the present invention.
Embodiment 1
Get each 2 parts of Herba Potentillae Discoloris, Cacumen Tamariciss, decoct with water twice, add for the first time 8 times of amounts that water is medical material weight, decoct 1h, add 6 times of amounts that water is medical material weight for the second time, decoct the 1h collecting decoction, be concentrated into 10 times of amounts of Herba Potentillae Discoloris, Cacumen Tamaricis gross weight, add 40 parts of sodium lauryl sulfate, 6 parts of lanolines, 70 ℃ of left and right sides are melt and dissolved, promptly.
Embodiment 2
Get each 4 parts of Herba Potentillae Discoloris, Cacumen Tamariciss, decoct with water twice, add for the first time 12 times of amounts that water is medical material weight, decoct 2h, add 10 times of amounts that water is medical material weight for the second time, decoct the 2h collecting decoction, be concentrated into 10 times of amounts of Herba Potentillae Discoloris, Cacumen Tamaricis gross weight, add 60 parts of sodium lauryl sulfate, 10 parts of lanolines, 80 ℃ of left and right sides are melt and dissolved, promptly.
Embodiment 3
Get each 3 parts of Herba Potentillae Discoloris, Cacumen Tamariciss, decoct with water twice, add for the first time 10 times of amounts that water is medical material weight, decoct 1.5h, add 8 times of amounts that water is medical material weight for the second time, decoct the 1.5h collecting decoction, be concentrated into 10 times of amounts of Herba Potentillae Discoloris, Cacumen Tamaricis gross weight, add 50 parts of sodium lauryl sulfate, 8 parts of lanolines, 75 ℃ of left and right sides are melt and dissolved, promptly.
Above-mentioned Chinese medicine Herba Potentillae Discoloris is the whole herb with root of Flos Rosae Multiflorae kind of plant Herba Potentillae Discoloris, and Cacumen Tamaricis is the browse of suspend machaka or dungarunga Ramulus et Folium Tamaricis.
Claims (1)
1. liquid soap, it is characterized in that, make by sodium lauryl sulfate 40-60 part, lanoline 6-10 part, Herba Potentillae Discoloris 2-4 part, Cacumen Tamaricis 2-4 part, preparation process is: get Herba Potentillae Discoloris, Cacumen Tamaricis, decoct with water twice, the 8-12 that adds for the first time water and be medical material weight doubly measures, decoct 1-2h, the 6-10 that adds for the second time water and be medical material weight doubly measures, decoct the 1-2h collecting decoction, be concentrated into 10 times of amounts of Herba Potentillae Discoloris, Cacumen Tamaricis gross weight, add sodium lauryl sulfate, lanoline, 70-80 ℃ melt and dissolved, promptly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012103527582A CN102824290B (en) | 2012-09-20 | 2012-09-20 | Liquid soap |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012103527582A CN102824290B (en) | 2012-09-20 | 2012-09-20 | Liquid soap |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102824290A CN102824290A (en) | 2012-12-19 |
| CN102824290B true CN102824290B (en) | 2013-07-24 |
Family
ID=47327738
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012103527582A Expired - Fee Related CN102824290B (en) | 2012-09-20 | 2012-09-20 | Liquid soap |
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| Country | Link |
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| CN (1) | CN102824290B (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103462848A (en) * | 2013-09-22 | 2013-12-25 | 南京正亮医药科技有限公司 | Soap |
| CN103540464A (en) * | 2013-10-18 | 2014-01-29 | 桂林雪芙莲日化有限公司 | Transparent cleaning liquid soap |
| CN103642614A (en) * | 2013-12-18 | 2014-03-19 | 淄博齐鼎立专利信息咨询有限公司 | Liquid soap |
| CN103666890B (en) * | 2013-12-19 | 2015-07-22 | 青岛琴诚医药技术有限公司 | Traditional Chinese medicinal liquid soap |
| CN103695218A (en) * | 2013-12-20 | 2014-04-02 | 青岛琴诚医药技术有限公司 | Plant liquid soap |
| CN103690439A (en) * | 2013-12-20 | 2014-04-02 | 青岛琴诚医药技术有限公司 | Liquid soap |
| CN106190655A (en) * | 2016-07-05 | 2016-12-07 | 兰汉斌 | A kind of child cleans liquid soap |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1670165A (en) * | 2005-04-16 | 2005-09-21 | 王浩贵 | Chinese goldthread cleaning products |
-
2012
- 2012-09-20 CN CN2012103527582A patent/CN102824290B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1670165A (en) * | 2005-04-16 | 2005-09-21 | 王浩贵 | Chinese goldthread cleaning products |
Non-Patent Citations (2)
| Title |
|---|
| 王晶等.翻白草的研究进展.《黑龙江医药》.2010,第23卷(第1期), |
| 翻白草的研究进展;王晶等;《黑龙江医药》;20101231;第23卷(第1期);第16页至第18页 * |
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| Publication number | Publication date |
|---|---|
| CN102824290A (en) | 2012-12-19 |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: SHANGHAI SOAP(GROUP) RUGAO CO., LTD. Free format text: FORMER OWNER: NANJING ZHENGLIANG PHARMACEUTICAL TECHNOLOGY CO., LTD. Effective date: 20130711 |
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| C41 | Transfer of patent application or patent right or utility model | ||
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Free format text: CORRECT: ADDRESS; FROM: 211300 NANJING, JIANGSU PROVINCE TO: 226521 NANTONG, JIANGSU PROVINCE |
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| TR01 | Transfer of patent right |
Effective date of registration: 20130711 Address after: Ding Yan Zhen Ding Xin Dong Lu, Rugao City, Jiangsu Province, Nantong City, No. 1, 226521 Patentee after: SHANGHAI SOAP GROUP RUGAO Co.,Ltd. Address before: Gu Tan Road Economic Development Zone in Gaochun County of Nanjing City, Jiangsu province 211300 branch No. 3 Building Room 607 Patentee before: Nanjing Zhengliang Medical Technology Co.,Ltd. |
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| TR01 | Transfer of patent right |
Effective date of registration: 20191126 Address after: Room 102-2, floor 1, block a, building 2, No. 58, Baozhen South Road, Baozhen, Chongming District, Shanghai 202157 (Shanghai Baozhen economic community) Patentee after: Shanghai Chaoling daily chemical products Co.,Ltd. Address before: Ding Yan Zhen Ding Xin Dong Lu, Rugao City, Jiangsu Province, Nantong City, No. 1, 226521 Patentee before: SHANGHAI SOAP GROUP RUGAO Co.,Ltd. |
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| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130724 Termination date: 20210920 |
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| CF01 | Termination of patent right due to non-payment of annual fee |