CN104000767B - A kind of Feminine care solution and preparation method thereof - Google Patents
A kind of Feminine care solution and preparation method thereof Download PDFInfo
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- CN104000767B CN104000767B CN201410270169.9A CN201410270169A CN104000767B CN 104000767 B CN104000767 B CN 104000767B CN 201410270169 A CN201410270169 A CN 201410270169A CN 104000767 B CN104000767 B CN 104000767B
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Abstract
The invention provides a kind of Feminine care solution, the object of female private part nursing is reached by heat clearing and damp drying, in order to reach this order ground, active component contained by it is prepared from by following raw materials in part by weight proportioning: bitter thorn 15-25 part, Herba Houttuyniae 10-20 part, Herba polygoni hydropiperis 20-30 part, JINHUA fruit 10-20 part, sorbitan monolaurate 3-5 part, glycerol 2-4 part, citric acid or sodium hydroxide adjust ph are 4.0, and have employed corresponding preparation method, this Feminine care solution is clean and degermation is effective, non-stimulated to the skin gentleness at female vulva position.
Description
Technical field
The present invention relates to female health technical field, be specifically related to a kind of Feminine care solution and preparation method thereof.
Background technology
The pudendum position of women needs to carry out cleaning-nursing with specific external nursing product, current use at most mainly has the medicinal lotion of disease therapy function, this lotion forms by multiple extracts of Chinese herbal medicine is composite often, its Main Function is to treat various gynaecopathia, plays medicinal effect.A class is also had to be the Feminine care solution mainly with cleaning and sterilizing function, its main component has been the surfactant of cleaning action and the antibacterial of a bactericidal action, its function is clean and bactericidal action, but there is destruction to the self purification of body self simultaneously, the immunocompetence of self can be reduced.Because the privileged sites of women inherently need to maintain certain pH value need the flora of some to exist, with the intrusion of resisting extraneous antibacterial with it to the infringement of healthy body.And the effect of surfactant in this type of conditioning liquid composition and antibacterial is very strong, the skin not only to relatively fragile is irritant, and can kill too much normal flora, destroys the sour environment of body self, reduces the self purification of self.
For overcoming the above-mentioned shortcoming of prior art; for women provides a kind of daily nursing product that may be used for pudendum position; now need a kind of Feminine care solution; not only require the effective of its clean and degermation; non-stimulated to the skin gentleness at female vulva position; and requirement has the effect of maintenance to the sour environment at this position and flora environment, nursing role can be played simultaneously.
Summary of the invention
Goal of the invention: in order to solve the problem, the object of the present invention is to provide a kind of Feminine care solution.
Another object of the present invention is to provide a kind of preparation method of Feminine care solution.
Technical scheme: the object of the invention is by following scheme realize:
A kind of Feminine care solution, active component contained by it is prepared from by following raw materials in part by weight proportioning: bitter thorn 15-25 part, Herba Houttuyniae 10-20 part, Herba polygoni hydropiperis 20-30 part, JINHUA fruit 10-20 part, sorbitan monolaurate 3-5 part, glycerol 2-4 part, citric acid or sodium hydroxide adjust ph are 4.0.
Described Feminine care solution, active component contained by it is prepared from by following raw materials in part by weight proportioning: bitter thorn 20 parts, Herba Houttuyniae 15 parts, Herba polygoni hydropiperis 10 parts, JINHUA fruit 15 parts, sorbitan monolaurate 4 parts, glycerol 3 parts, citric acid or sodium hydroxide adjust ph are 4.0.
Described Feminine care solution, preparation method comprises the steps: that getting bitter thorn, Herba Houttuyniae, Herba polygoni hydropiperis and JINHUA fruit medical material merges, decoct with water twice, add water as 10 times amount of medical material weight at every turn, decoct 2h, collecting decoction, when being concentrated into 65 DEG C, relative density is 1.10, adding ethanol makes the percent by volume of alcohol content reach 65%, stirs, and leaves standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.20 and reclaims ethanol, adds sorbitan monolaurate, G & W, is 4.0 by citric acid or sodium hydroxide adjust ph.
Beneficial effect:
From theory of Chinese medical science, bitter thorn heat-clearing and toxic substances removing, removing dampness and killing parasites in we, be monarch drug, Herba polygoni hydropiperis removing dampness and killing parasites is ministerial drug, increases the insecticidal action of monarch drug, and Herba Houttuyniae and JINHUA fruit are adjuvant, and all medicines are harmonious, and play antipyretic and antidote functions altogether, for feminine care.Formulation is reasonable, and compatibility is rigorous, consists of Chinese crude drug, has no side effect, low price.Integrate three kinds of functions of cleaning, degerming, nursing, emphasizing that cleaning more emphasizes Nutritional Nursing Care while degerming, not only can effective cleaning sterilization, more can meet the multiple demand of privileged sites cleaning, safety and comfort, have no side effect, can for a long time for daily cleaning-nursing.
Detailed description of the invention
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
One, embodiment 1,
Get bitter thorn 20g, Herba Houttuyniae 15g, Herba polygoni hydropiperis 10g, JINHUA fruit 15g, merge, decoct with water twice, add water as 10 times amount of medical material weight at every turn, decoct 2h, collecting decoction, when being concentrated into 65 DEG C, relative density is 1.10, adding ethanol makes the percent by volume of alcohol content reach 65%, stirs, and leaves standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.20 and reclaims ethanol, adds sorbitan monolaurate 4g, glycerol 3g and water, is 4.0 by citric acid or sodium hydroxide adjust ph.
Two, conditioning liquid extracorporeal bacteria inhibitor test of the present invention
2.1 test materials: conditioning liquid of the present invention, prepare by embodiment 1 preparation method.Penicillin sodium: Huabei Pharmaceutic Co., Ltd's specification: 800,000 units/bottle lot number: Y1105154 sodium chloride, Shanghai hundred million chemical reagent company limiteies of a specified duration, lot number: 00080130.Nutrient broth, CAS Shanghai Insect Bio Technological Development Co., Ltd., lot number: 110230.Nutrient agar, microorganism reagent factory of Jiangsu Prov. Disease Preventing and Controlling Center, lot number: 110016.Calf serum, Hangzhou Sijiqing Biological Engineering Material Co., Ltd., lot number: 110408; De-fine Sheep Blood, purchased from Sheep Blood supply station, Nanjing, lot number: 110903 Clinical isolation: staphylococcus aureus, escherichia coli, B-mode micrococcus scarlatinae, Candida albicans, is provided by Jiangsu Prov. People's Hospital microbial room isolation identification.
Instrument and equipment: electronic balance, Beijing Sai Duolisi balance company limited produces; Full-automatic high-pressure autoclave, Japanese SANYO; ; Superclean bench, Suzhou Decontamination Equipment Plant; Water isolation type constant incubator, the permanent Science and Technology Ltd. in Shanghai one
2.2 experimental technique
2.2.1 Zengjing Granule: get Clinical isolation staphylococcus aureus, escherichia coli, B-mode micrococcus scarlatinae, albicans strain a little, be inoculated in respectively in broth bouillon, cultivates 18h for 37 DEG C.(adding 20% calf serum in B-mode micrococcus scarlatinae broth bouillon) gets each bacterial strain nutrient broth culture that 18h cultivates, and does 10-3 dilution for experiment with nutrient broth.
2.2.2 doubling dilution (test tube method): get sterilizing test tubes 11,1st pipe adds nutrient broth fluid medium 1.6mL, all the other are pipe 1mL often, getting conditioning liquid of the present invention respectively adds in the first pipe, 1mL is got to the 2nd pipe after mixing, dilute successively, the 10th pipe sucking-off 1mL discards, and the 11st pipe does not add medicinal liquid in contrast.Often pipe adds dilution bacterium liquid 0.1mL, cultivates 24h for 37 DEG C, takes out and observe bacterial growth situation.As drug liquid tube is muddy, namely represent bacterial growth, for reagent thing without bacteriostasis; As drug liquid tube is limpid, represent that bacterial growth is suppressed, the medicinal liquid of the greatest dilution of its energy bacteria growing inhibiting, is the minimal inhibitory concentration (MIC) of this medicine.By limpid medicinal liquid meat soup each pipe transferred species broth agar plates, cultivate 24h and observe, be still the bacteriocidal concentration of this medicine without the minimum drug level of bacterial growth.Get penicillin sodium (being made into 160,000 units/mL) as stated above, to dilute successively, cultivate, make positive control.
2.3 experimental result displays: conditioning liquid of the present invention all has stronger bacteriostasis to clinical isolates staphylococcus aureus, escherichia coli, B-mode micrococcus scarlatinae, Candida albicans, MIC, at 10mg ~ 100mg/mL, shows that the present invention has vitro antibacterial activity.
2.4 experiment conclusion: conditioning liquid of the present invention all has stronger bacteriostasis to clinical isolates staphylococcus aureus, escherichia coli, B-mode micrococcus scarlatinae, Candida albicans, MIC is at 10mg ~ 100mg/mL, show that conditioning liquid of the present invention has vitro antibacterial activity, can be used for feminine care.
Claims (2)
1. a Feminine care solution, it is characterized in that, active component contained by it is prepared from by following raw materials in part by weight proportioning: bitter thorn 20 parts, Herba Houttuyniae 15 parts, Herba polygoni hydropiperis 10 parts, JINHUA fruit 15 parts, sorbitan monolaurate 4 parts, glycerol 3 parts, citric acid or sodium hydroxide adjust ph are 4.0.
2. Feminine care solution as claimed in claim 1, it is characterized in that, preparation method comprises the steps: to get bitter thorn, Herba Houttuyniae, Herba polygoni hydropiperis and JINHUA fruit medical material merge, decoct with water twice, add water as 10 times amount of medical material weight at every turn, decoct 2h, collecting decoction, when being concentrated into 65 DEG C, relative density is 1.10, adding ethanol makes the percent by volume of alcohol content reach 65%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.20 and reclaims ethanol, add sorbitan monolaurate, G & W, be 4.0 by citric acid or sodium hydroxide adjust ph.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410270169.9A CN104000767B (en) | 2014-06-18 | 2014-06-18 | A kind of Feminine care solution and preparation method thereof |
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| CN201410270169.9A CN104000767B (en) | 2014-06-18 | 2014-06-18 | A kind of Feminine care solution and preparation method thereof |
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| CN104000767A CN104000767A (en) | 2014-08-27 |
| CN104000767B true CN104000767B (en) | 2016-02-24 |
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Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104887768A (en) * | 2015-05-26 | 2015-09-09 | 徐艳 | Female traditional Chinese medicine care solution and preparation method thereof |
| CN104840843A (en) * | 2015-05-30 | 2015-08-19 | 陈爱华 | Female care solution and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103223110A (en) * | 2013-04-30 | 2013-07-31 | 布焕景 | External traditional Chinese medicine composition for treating female pruritus vulvae and preparation method thereof |
| CN103564101A (en) * | 2013-10-09 | 2014-02-12 | 陈友望 | Health-protection herb tea formula |
| CN103705649A (en) * | 2014-01-11 | 2014-04-09 | 孙永丽 | Sterilization disinfectant used for clinical laboratory and preparation method of sterilization disinfectant |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103223110A (en) * | 2013-04-30 | 2013-07-31 | 布焕景 | External traditional Chinese medicine composition for treating female pruritus vulvae and preparation method thereof |
| CN103564101A (en) * | 2013-10-09 | 2014-02-12 | 陈友望 | Health-protection herb tea formula |
| CN103705649A (en) * | 2014-01-11 | 2014-04-09 | 孙永丽 | Sterilization disinfectant used for clinical laboratory and preparation method of sterilization disinfectant |
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Inventor after: Xu Jie Inventor after: Yan Chunlan Inventor after: Xin Quanjun Inventor after: Xing Meiqun Inventor before: Xu Yan |
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Effective date of registration: 20160125 Address after: 262100 Xingan Street Health Center, Shandong, Anqiu Applicant after: Xu Jie Address before: 211224, No. 18, industrial town, crystal Town, Lishui District, Jiangsu, Nanjing Applicant before: Xu Yan |
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