CN106342946B - A kind of air purifying and sterilizing agent and preparation method - Google Patents
A kind of air purifying and sterilizing agent and preparation method Download PDFInfo
- Publication number
- CN106342946B CN106342946B CN201610629342.9A CN201610629342A CN106342946B CN 106342946 B CN106342946 B CN 106342946B CN 201610629342 A CN201610629342 A CN 201610629342A CN 106342946 B CN106342946 B CN 106342946B
- Authority
- CN
- China
- Prior art keywords
- parts
- essential oil
- hydrosol
- plants essential
- sterilization
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
- A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
- A01N31/08—Oxygen or sulfur directly attached to an aromatic ring system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
- A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
- A01N43/14—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings
- A01N43/16—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings with oxygen as the ring hetero atom
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/40—Liliopsida [monocotyledons]
- A01N65/44—Poaceae or Gramineae [Grass family], e.g. bamboo, lemon grass or citronella grass
Abstract
The present invention discloses a kind of air purifying and sterilizing agent and preparation method, and the air purifying and sterilizing agent is made up of the following each component represented with mass fraction：0.2~1 part of plants essential oil；0.02~3 part of matrine；0.01~0.1 part of Thymol；0.02~3 part of Osthole；15~50 parts of the plant hydrosol used, 10~20 parts of food-grade ethanol, pure appropriate amount of water, appropriate pH adjusting agent of arranging in pairs or groups corresponding with plants essential oil (appropriate pH adjusting agent makes the pH value of the disinfectant solution prepared be maintained between 6.0 7.0).Each component compatibility of the present invention is stable, promote mutually, particularly adding plant hydrosol can promote various plant source components to interact, effect that sterilization, sterilization etc. purify the air of a room farthest is played, while solving homogeneity and stability of these sterilization components in mutual compatibility.
Description
Technical field
The present invention relates to air cleaning antivirus technique, more particularly, to a kind of air purifying and sterilizing agent and preparation method.
Background technology
Room air is closely bound up with health.Such as, because fitting up or adding new furniture, or not smooth all possible dirt of divulging information
Air is contaminated, makes to contain noxious material in air, endangers our health.And for example, hospital is that a population amount of flow is big, Ren Yuanmi
The of a relatively high place of collection, infection source density, and the operating room of hospital, ICU, Burn Ward, Neonatal Ward, laboratory
There is very high requirement to air quality Deng place, it is necessary to the air purifying and sterilizing in hospital room.
Air cleaner sterilization is divided into static sterilization and dynamic disinfection method again.Static sterilization is the interior space of closing
In, spray-on process sprays certain density air purifying and sterilizing agent, sterilizes 2-4 hours, the clump count in measuring chamber before and after sterilization, meter
Calculate average sterilization rate；Dynamic disinfection method is that air purifying and sterilizing agent is placed in the interior space of closing, and indoor work is not influenceed
Make, Site Detection place/does not place the clump count in the space of air purifying and sterilizing agent, calculate average sterilization rate.
General air purifying and sterilizing agent on the market at present, though bragging about its bactericidal effect, can only often give out of short duration
Fragrance, air freshener can only be referred to as at most, therefore, the air of effective sterilizing on the premise of health such as why not is influenceed
Bactericide turns into problem；
In addition, when above-mentioned static sterilization and dynamic disinfection method apply air disinfectant, how do one's best increasing
The bactericidal effect of big air disinfection agent, also as problem in the industry.
The content of the invention
In view of prior art is generally emulsion using the air purifying and sterilizing agent of vegetable-derived components, antivirus clean-up effect it is not good or
Person contains a large amount of chemical components and makees auxiliary agent and be not suitable for disinfection of indoor air sterilization, and the present invention proposes a kind of air purifying and sterilizing
Agent and preparation method, each component compatibility is stable, promote mutually, and various plant source component phases can be promoted by particularly adding plant hydrosol
Interaction, farthest plays effect that sterilization, sterilization etc. purify the air of a room, while solving these sterilization components mutual
Homogeneity and stability during compatibility.
A kind of air purifying and sterilizing agent, is made up of the following each component represented with mass fraction：0.2~1 part of plants essential oil,
0.02~3 part of matrine, 0.01~0.1 part of Thymol, 0.02~3 part of Osthole, collocation corresponding with plants essential oil makes
15~50 parts of plant hydrosol, 10~20 parts of food-grade ethanol, qs pH adjuster, appropriate amount of purified water；
Wherein, plants essential oil is that refined jasmine oil, blue or green bamboo essential oil, Lavender, tea tree ethereal oil, chamomile essential oil or fan change
Essential oil, corresponding, plant hydrosol is respectively that jasmine hydrosol, lavender hydrosol, tea tree hydrosol, chamomile hydrosol or rosemary are pure
Dew.
In one embodiment, the air purifying and sterilizing agent is made up of the following each component represented with mass fraction：Plant
0.2 part of thing essential oil；0.02 part of matrine；0.01 part of Thymol；0.02 part of Osthole；Collocation corresponding with plants essential oil makes
15 parts of plant hydrosol, 10 parts of food-grade ethanol, pure appropriate amount of water, appropriate pH adjusting agent.
In one embodiment, the air purifying and sterilizing agent is made up of the following each component represented with mass fraction：Plant
1 part of thing essential oil；3 parts of matrine；0.1 part of Thymol；3 parts of Osthole；The plant used of arranging in pairs or groups corresponding with plants essential oil
50 parts of hydrosol.20 parts of food-grade ethanol, pure appropriate amount of water, appropriate pH adjusting agent.
In one embodiment, the air purifying and sterilizing agent is made up of the following each component represented with mass fraction：Plant
0.5 part of thing essential oil；2 parts of matrine；0.05 part of Thymol；2 parts of Osthole；The plant used of arranging in pairs or groups corresponding with plants essential oil
45 parts of thing hydrosol.15 parts of food-grade ethanol, pure appropriate amount of water, appropriate pH adjusting agent.
Wherein, the air purifying and sterilizing agent also includes appropriate Aloe Vera Gel.
A kind of preparation method of air purifying and sterilizing agent, it includes step：Take 0.2~1 part of plants essential oil, matrine 0.02
~3 parts, 0.01~0.1 part of Thymol, 0.02~3 part of Osthole, the plant used of arranging in pairs or groups corresponding with plants essential oil is pure
15~50 parts of dew, 10~20 parts of food-grade ethanol；0.02~3 part of 0.02~3 part of matrine and Osthole are dissolved in 2-6 parts
Food-grade ethanol solution, obtains the first mixed solution；0.01~0.1 part of food-grade ethanol for being dissolved in 2-4 parts of Thymol is molten
In liquid, do not stop stirring until dissolving obtains the second mixed solution；0.2~1 part of plants essential oil is taken to be dissolved in remaining food-grade ethanol
In solution, do not stop stirring until being completely dissolved and obtain the 3rd mixed solution；By above-mentioned first, second, and third mixed solution difference
Three is well mixed again after standing 12-36 hours, the plant extract hydrosol arranged in pairs or groups and used corresponding with plants essential oil is then added
15~50 parts, appropriate amount of purified water trim is added, and add qs pH adjuster so that the pH value of final mixed solution is maintained at
Between 6.0-7.0, final mixed solution is stood 10-15 days until fusion completely turns into the liquid of transparent and homogeneous.
The present invention, which is solved by following technical spirit, " does not influence the air disinfection of effective sterilizing on the premise of health
The technical barrier of the problem of agent, the bactericidal effect of increase air disinfection agent "：
1. bacteriostatic agent：Plant hydrosol+corresponding plants essential oil, inventor has found that hydrosol coordinates essential oil, to using essential oil merely
Or the simple fungistatic effect using plant hydrosol has synergistic effect, hydrosol coordinates the bacteriostatic activity of essential oil higher than expection activity
10%.
2. bactericide：Matrine+Osthole+Thymol, is sterilized in antibacterial environment, and the two can produce collaboration and increase
Effect is acted on, and the air sterilizing activity of bacteriostatic agent+antimicrobial combination is higher than expection activity more than 16%, achieves unexpected
Technique effect.
3. Ultramicro-powder suspension formulation, the sterilization aqua presses 2-3 with carrier:1 ratio is mixed and made into Ultramicro-powder suspension formulation,
Either spray and be also located in atmosphere in open-top receptacle, compared to aqua, considerably increase the ratio surface with air contact
Product, the air sterilizing activity for having the Ultramicro-powder suspension formulation of carrier is higher than more than the 20% of expection activity, and bactericidal effect is more
Plus show.
The application is by above bacteriostatic agent+bactericide, and the technological means for further adding Ultramicro-powder to suspend makes air cleaning disappear
Toxic agent is sterilized on the basis of antibacterial, and sterilizing and purifying purpose the bacterium put in air, virus and pathogenic microorganism, and danger
The organic pollutions such as formaldehyde, benzene, the ozone of evil health, reduce the usage amount of alcohols solvent, are ensuring product dissipation effect
On the basis of, the safety in utilization and stability of product are improved, can be used safely whenever and wherever possible, and farthest performance disappears
Effect that poison, sterilization etc. purify the air of a room, achieves unexpected purifying sterilizing effect.
Embodiment
The application proposes a kind of air purifying and sterilizing agent, mainly using plant source sterilizing compound prescription, safety non-toxic,
Have no side effect, noresidue is used at any time, can be rapidly and efficiently room air is carried out disinfection, sterilizes to purify the air of a room,
The bacterium killed in air, virus can effectively be pressed down, its sterilizing rate reaches 99.7% after testing.
A kind of air purifying and sterilizing agent, including sterilization aqua, the sterilization aqua by with mass fraction represent it is following each
Component is constituted：0.2~1 part of plants essential oil；0.02~3 part of matrine；0.01~0.1 part of Thymol；Osthole 0.02~3
Part；15~50 parts of the plant hydrosol used, 10-20 parts of food-grade ethanol, pure appropriate amount of water, pH of arranging in pairs or groups corresponding with plants essential oil
Appropriate conditioning agent (appropriate pH adjusting agent makes the pH value of the disinfectant solution prepared be maintained between 6.0-7.0).
Wherein, plants essential oil is that refined jasmine oil, blue or green bamboo essential oil, Lavender, tea tree ethereal oil, chamomile essential oil or fan change
Essential oil, plant hydrosol is jasmine hydrosol, lavender hydrosol, tea tree hydrosol, chamomile hydrosol or rosemary hydrosol.Also, its
Used between a kind of middle plants essential oil and one of which plant hydrosol using not influenceing essential oil smell to carry out collocation as principle, such as,
Lavender is used with the collocation of lavender hydrosol, chamomile essential oil and chamomile hydrosol collocation are used.
It is further preferred that the air purifying and sterilizing agent, in addition to carrier, the carrier is talcum powder, starch or treasure
Pearl powder, the carrier water content is less than 7%.The carrier wears into superfine powder using fluid energy mill, and particle diameter D90 is respectively less than 5 microns,
Particle diameter is significantly less than conventional wettable powder, and it is intuitively shown on suspensibility.The superfine powder is in cloud in water
Diffusion, with good dispersiveness and suspension, suspensibility up to more than 98%.
The sterilization aqua presses 2-3 with carrier:1 ratio is mixed and made into Ultramicro-powder suspension formulation.The Ultramicro-powder, which suspends, to be made
The operation principle of agent is：Carrier is suspended in sterilization aqua, carrier absorption sterilization aqua, and when being sprayed in atmosphere,
Absorb full Ultramicro-powder to be suspended in air, the contact area of sterilization aqua and air molecule considerably increased by carrier,
The aerial broad covered area of sterilization aqua of unit mass, far ahead of other regular dosage forms, makes the sterilization of sterilization aqua
Activity is farthest played, and bactericidal effect is notable.The carrier be not with sterilize aqua component have an effect it is lazy
Property material, only serve absorption medicament, in atmosphere the effect of quick diffusion medicament.
It is as follows that the preparation method of the air purifying and sterilizing agent includes step：(1) 0.2~1 part of plants essential oil, matrine are taken
0.02~3 part, 0.01~0.1 part of Thymol, 0.02~3 part of Osthole, the plant used of arranging in pairs or groups corresponding with plants essential oil
15~50 parts of thing hydrosol, 10~20 parts of food-grade ethanol；(2) 0.02~3 part of 0.02~3 part of matrine and Osthole is taken to be dissolved in
2-6 parts of food-grade ethanol, obtains the first mixed solution；(3) food-grade for taking 0.01~0.1 part of Thymol to be dissolved in 2-4 parts
In ethanol solution, do not stop stirring until dissolving obtains the second mixed solution；(4) 0.2~1 part of plants essential oil is taken to be dissolved in remaining food
In grade ethanol solution, do not stop stirring until being completely dissolved and obtain the 3rd mixed solution；(5) by above-mentioned first, second, and third
Mixed solution stands again be well mixed three after 12-36 hours respectively, adds the plant arranged in pairs or groups and used corresponding with plants essential oil
Thing extracts 15~50 parts of hydrosol, adds appropriate amount of purified water trim, and add qs pH adjuster and cause final mixed solution
PH value is maintained between 6.0-7.0, and final mixed solution is stood into 10-15 days until fusion completely turns into the liquid of transparent and homogeneous
Body, that is, prepare the sterilization aqua of the air purifying and sterilizing agent of the present invention.
It is further preferred that the preparation method also includes：The sterilization aqua and carrier are pressed into 2-3:1 ratio is mixed simultaneously
Stir and Ultramicro-powder suspension formulation is made.
The each component compatibility of the disinfectant of the application is stable, promote mutually.Plant hydrosol is used with plants essential oil collocation,
Plant hydrosol can promote the component of plant source to interact, and farthest play what sterilization, sterilization etc. purified the air of a room
Effect；Plant hydrosol does not only have bactericidal effect with plants essential oil, and containing a variety of skin care ingredients, uses safety；Also, plant
Essential oil also provides the effect of crucial touch in the disinfectant of the application, and plants essential oil is except that can provide lasting curative effect of releiving
Outside, moreover it is possible to make human body more self-confident and keep the calmness of heart.Matrine and Osthole are mutually compatible, and mutually promoting has very well
Bactericidal effect.Thymol is to be not only natural antibacterial, anti-sense and disinfectant, or pure natural preservative.
Also, various plant hydrosols contain the Sesquiterpene Polyesterss of a variety of similar structures, Thymol can be made preferably molten
Solution, fusion so that the stability of product is improved, so as to play bigger bactericidal effect.Because Osthole, Thymol are in water
In solute effect it is insoluble or not good, and both at home and abroad on for indoor sterile products VOC (Volatile Organic
Compounds initials are abbreviated as VOC, refer to VOC) amount no more than 20%, though and ethanol is fine
Solvent, but in view of security regulations, its content must not exceed 20%, and this product is disappeared using completely pure natural safe again
Malicious composition, at the same in order to keep the stabilization of product pH value make product be in faintly acid state, must not be dissolved using alkaline solution this two
Plant composition.If Osthole, Thymol this 2 components are blended in into appearance in the middle part of aqua, easily occur it is muddy, turn white and
The bad result of sense organ, in order to avoid such case, the application employs plant hydrosol farthest to cause Osthole
Dissolved well with Thymol so that final product for it is transparent, clear, stably, sense organ is comfortable and smell is soft, fit
Sprinkling for room air.
Embodiment 1
A kind of air purifying and sterilizing agent, is made up of the following each component represented with mass fraction：0.2 part of plants essential oil is bitter
Join 0.02 part of alkali, 0.01 part of Thymol, 0.02 part of Osthole, the plant hydrosol 15 used of arranging in pairs or groups corresponding with plants essential oil
Part, 10 parts of food-grade ethanol, qs pH adjuster, appropriate amount of purified water.
Embodiment 2
A kind of air purifying and sterilizing agent, is made up of the following each component represented with mass fraction：1 part of plants essential oil, kuh-seng
3 parts of alkali, 0.1 part of Thymol, 3 parts of Osthole, 50 parts of the plant hydrosol used, food-grade of arranging in pairs or groups corresponding with plants essential oil
20 parts of ethanol, qs pH adjuster, appropriate amount of purified water.
Embodiment 3
A kind of air purifying and sterilizing agent, is made up of the following each component represented with mass fraction：0.5 part of plants essential oil is bitter
Join 2 parts of alkali, 0.05 part of Thymol, 2 parts of Osthole, 45 parts of the plant hydrosol used of arranging in pairs or groups corresponding with plants essential oil, food
15 parts of grade ethanol, qs pH adjuster, appropriate amount of purified water.
In above-described embodiment 1-3, plants essential oil is that refined jasmine oil, blue or green bamboo essential oil, Lavender, tea tree ethereal oil, ocean are sweet
Chrysanthemum essential oil or Rosemary Oil, corresponding, plant hydrosol is respectively that jasmine hydrosol, lavender hydrosol, tea tree hydrosol, chamomile are pure
Dew or rosemary hydrosol.
The shelf-life of the disinfectant prepared using embodiment 3 as 24 months, with every tanks of 10ml mono- carry out filling and package into
Sample, takes 100 samples after the keeping of 24 months, each sample is still the liquid of transparent and homogeneous.Again after 12 months
Keeping, only wherein 2 samples have lacked white opacity, and remaining 98 sample is still the liquid of transparent and homogeneous, randomly selects 5
After bottle sample is opened, the liquid odour of ejection is suitable.It can thus be seen that the homogeneity and stably of disinfectant prepared by the application
Property is very good！
With the foundation of embodiment 3《Disinfection technology standard》(version in 2012) is respectively to of the invention empty under respective testing conditions
The bacteriostasis property of gas disinfectant is detected that specific testing result is as follows：
1) the air purifying and sterilizing agent for preparing embodiment 3 is to staphylococcus aureus of the concentration for 2.6 × 104cfu/mL
Experiment acts on 2min, bacteriostasis rate ＞ 99.9% with bacteria suspension, and product has bacteriostasis for staphylococcus aureus.
2) by embodiment 3 prepare without canned air purifying and sterilizing agent to concentration be 2.9 × 104cfu/mL large intestine
The experiment of bacillus bacterium acts on 2min, bacteriostasis rate ＞ 99.3% with bacteria suspension, and product has bacteriostasis for Escherichia coli.
3) to the control of air-borne bacteria content：The closed room of 20 square meters between selection three, is carried out in the case of nobody indoors
Sterilizing effect observing.Before sterilization, natural bacteria sampling is carried out with six grades of sieve aperture air impact formula samplers, before sterilization
Sample.Air purifying and sterilizing agent prepared by Example 3, closed room carries out disinfection 3 respectively, and spray amount is 2ml/
m3.Act on after 20min, sample respectively, be used as sample after sterilization.Sampling flat board is directly placed into culture 48 in 37 DEG C of incubators small
When, count growth clump count.Disinfection efficiency=(sample bacterium number after sample bacterium number-sterilization before sterilization) preceding sample bacterium number of/sterilization ×
100%.Result of the test：Sample bacterium number is 26028cfu/m before sterilization3, the sample bacterium number after sterilization is 66cfu/m3, sterilization rate is
99.75%, as a result show, air sanitizer prepared by the present invention has good bacteria-eliminating efficacy.
The mechanism of action explanation of the air sanitizer：
1st, inventors be surprised to learn that, hydrosol coordinates essential oil, and using essential oil or simple the antibacterial of plant hydrosol is used to simple
Effect has synergistic effect, and hydrosol coordinates the bacteriostatic activity of essential oil to be higher than expection activity 10%；Bactericide matrine+Osthole+
The addition of Thymol, synergistic function is produced with hydrosol+essential oil, and the air sterilizing of bacteriostatic agent+antimicrobial combination is lived
Property be higher than expection activity more than 16%.
Experiment presented below and experimental verification data are as follows：
Sterile nutrient agar and sabouraud's agar flat board is prepared, 0.2ml indicator bacteria stostes are added, coating is uniform, and band is made
Bacterio-agar flat board；Uniform diameter 5mm filter papers are separately got with card punch, 5mm filter papers are immersed in difference after sterilizing
Tested sterilization aqua in, control be soaked in sterile saline；4, which are sticked, in the surrounding for the agar plate that carries disease germs steeped tested
Sterilize the filter paper of aqua, centre, which is sticked, steeped the filter paper of physiological saline and compare.Bacterium in 37 DEG C cultivate 24h, fungi in
30 DEG C of culture 48h, record the size of inhibition zone, the culture longer time, observe by the naked eye subsequent growth situation.
Bacteria suspension：Escherichia coli 8099 and staphylococcus aureus ATCC6538 are seeded on nutrient agar in 37 DEG C of cultures
5.0 × 10 are made into physiological saline for 18~24h, scraping lawn7~5.0 × 108CFU/ml stoste；Bacillus subtilis is black
Discoloration kind ATC9372 gemma cultivates 5~7d on nutrient agar in 37 DEG C, and 5.0 × 10 are prepared into physiological saline7~5.0
×108CFU/ml stoste；；Candida albicans ATCC10231 and aspergillus niger ATCC16404 are seeded on sabouraud's agar, 30 DEG C
2~5d is cultivated, 5.0 × 106~5.0 × 107CFU/ml stoste is made into physiological saline for scraping lawn or aspergillus niger spore.
The paper disk method of table 1 evaluates the fungistatic effect of 3 kinds of tested sterilization aquas
A：50 parts of lavender hydrosol, 0 part of Lavender, 15 parts of food-grade ethanol, qs pH adjuster, surplus pure water
The sterilization aqua of composition.
B：0 part of lavender hydrosol, 1 part of Lavender, 15 parts of food-grade ethanol, qs pH adjuster, surplus pure water
The sterilization aqua of composition.
C：50 parts of lavender hydrosol, 1 part of Lavender, 15 parts of food-grade ethanol, qs pH adjuster, surplus pure water
The sterilization aqua of composition.
D：3 parts of matrine；3 parts of Osthole, 0.1 part of Thymol, 15 parts of food-grade ethanol, qs pH adjuster is remaining
Measure the sterilization aqua of pure water composition.
E:50 parts of lavender hydrosol, 1 part of Lavender, 3 parts of matrine；3 parts of Osthole, 0.1 part of Thymol, food
15 parts of grade ethanol, qs pH adjuster, the sterilization aqua of surplus pure water composition.
2nd, bactericide can produce synergistic function in the environment of bacteriostatic agent, and the air of bacteriostatic agent+antimicrobial combination is killed
Bacterium antimicrobial activity is higher than more than the 16% of expection activity, and the air sterilizing activity for having the Ultramicro-powder suspension formulation of carrier is higher than
More than the 20% of expection activity.
Find after further study, 0.02~3 part of matrine is added in formula；0.02~3 part of Osthole, thyme
Increase bactericidal effect on the basis of 0.01~0.1 part of phenol is antibacterial to air.
Tested using Active sterilization：During medical worker's normal work, sterilization aqua is placed in clinic, indoor sterilization aqua
Concentration is 4mg/m3 after volatilization, and the fluctuation range of the clinic air-borne bacteria of Site Detection two is every two hours detected once, continuous 10
My god, detect 60 times altogether.Clinic 1 sterilizes aqua D air-borne bacteria clump count in 70~300CFU/m3 scopes by side.The air of clinic 2
Bacteria colony count is in 40~150CFU/m3 scopes.The average flow of the people of clinic 1 is more than clinic 2.Its Active sterilization effect is shown in attached
Table.
Fungistatic effect (the CFU/m of the tested sterilization aqua of 24 kinds of table3)
Explanation：Left column is the detection data of clinic 1, and right column is the detection data of clinic 2, and data are the flat of three experiments
Average.
A：50 parts of lavender hydrosol, 1 part of Lavender, 3 parts of matrine, 15 parts of food-grade ethanol, qs pH adjuster,
The sterilization aqua of surplus pure water composition.
B：50 parts of lavender hydrosol, 1 part of Lavender, 3 parts of Osthole, 15 parts of food-grade ethanol, appropriate pH regulations
Agent, the sterilization aqua of surplus pure water composition.
C：50 parts of lavender hydrosol, 1 part of Lavender, 3 parts of matrine, 3 parts of Osthole, 15 parts of food-grade ethanol,
Qs pH adjuster, the sterilization aqua of surplus pure water composition.
D：50 parts of lavender hydrosol, 1 part of Lavender, 3 parts of matrine, 3 parts of Osthole, 0.1 part of Thymol, food
15 parts of grade ethanol, qs pH adjuster, the sterilization aqua of surplus pure water composition.
E：25 parts of 50 parts+carriers of sterilization aqua D are mixed into Ultramicro-powder suspension formulation.
F：50 parts of lavender hydrosol, 1 part of Lavender, 15 parts of food-grade ethanol, qs pH adjuster, surplus pure water
The sterilization aqua of composition.
Find out from above-mentioned experimental data, individually apply matrine, Osthole, merge and apply matrine, Osthole, it is killed
The synergistic effect of bacterium is remarkably reinforced.And further coordinate Thymol, then it can coordinate with matrine, Osthole and further enhance
Bactericidal effect.
The addition of bactericide matrine+Osthole+Thymol, produces Synergistic with bacteriostatic agent hydrosol+essential oil and makees
With the air sterilizing activity of bacteriostatic agent+antimicrobial combination is higher than more than the 16% of expection activity.And have the Ultramicro-powder of carrier
Suspension formulation air sterilizing activity be higher than expection activity more than 20%, and preceding 6 hours bactericidal effects be significantly stronger than it is super
The bactericidal effect for spending 6 hours, this absolutely proves that Ultramicro-powder suspension formulation effect of volatilizing in atmosphere is more obvious, but the duration
In 6 hours, more than 6 hours, then effect was successively decreased.
Claims (5)
1. a kind of air purifying and sterilizing agent, it is characterised in that
Including sterilization aqua, the sterilization aqua is made up of the following each component represented with mass fraction：Plants essential oil 0.2~1
Part, 0.02~3 part of matrine, 0.01~0.1 part of Thymol, 0.02~3 part of Osthole, collocation corresponding with plants essential oil
15~50 parts of the plant hydrosol used, 10~20 parts of food-grade ethanol, pure appropriate amount of water, appropriate pH adjusting agent；
Wherein, plants essential oil is refined jasmine oil, blue or green bamboo essential oil, Lavender, tea tree ethereal oil, chamomile essential oil or rosemary essence
Oil, corresponding, plant hydrosol is respectively jasmine hydrosol, lavender hydrosol, tea tree hydrosol, chamomile hydrosol or rosemary hydrosol；
Also include carrier, the carrier is talcum powder, starch or pearl powder, and it is equal that the carrier wears into particle diameter D90 using fluid energy mill
Superfine powder less than 5 microns, the sterilization aqua presses 2-3 with carrier:1 ratio is mixed and made into Ultramicro-powder suspension formulation.
2. air purifying and sterilizing agent according to claim 1, it is characterised in that the sterilization aqua with mass fraction by being represented
Following each component composition：0.2 part of plants essential oil, 0.02 part of matrine, 0.01 part of Thymol, 0.02 part of Osthole, with
Corresponding 15 parts of the plant hydrosol used, 10 parts of food-grade ethanol, pure appropriate amount of water, appropriate pH adjusting agent of arranging in pairs or groups of plants essential oil.
3. air purifying and sterilizing agent according to claim 1, it is characterised in that the sterilization aqua with mass fraction by being represented
Following each component composition：1 part of plants essential oil, 3 parts of matrine, 0.1 part of Thymol, 3 parts of Osthole, with plants essential oil phase
Correspondingly arrange in pairs or groups 50 parts of the plant hydrosol used, 20 parts of food-grade ethanol, pure appropriate amount of water, appropriate pH adjusting agent.
4. air purifying and sterilizing agent according to claim 1, it is characterised in that the sterilization aqua with mass fraction by being represented
Following each component composition：0.5 part of plants essential oil, 2 parts of matrine, 0.05 part of Thymol, 2 parts of Osthole, with plant essence
Oil phase is correspondingly arranged in pairs or groups 45 parts of the plant hydrosol used, 15 parts of food-grade ethanol, pure appropriate amount of water, appropriate pH adjusting agent.
5. a kind of preparation method of the air purifying and sterilizing agent as described in claim 1-4 is any, it is characterised in that including step：
（One）The preparation of aqua is sterilized,
1）Take 0.2~1 part of plants essential oil, 0.02~3 part of matrine, 0.01~0.1 part of Thymol, Osthole 0.02~3
Part, 15~50 parts of the plant hydrosol used, 10~20 parts of food-grade ethanol of arranging in pairs or groups corresponding with plants essential oil；
2）0.02~3 part of 0.02~3 part of matrine and Osthole are dissolved in 2-6 parts of food-grade ethanol, the first mixing is obtained
Solution；
3）By Thymol, 0.01~0.1 part is dissolved in 2-4 parts of food-grade ethanol, does not stop stirring and is mixed until dissolving and obtaining second
Close solution；
4）Take 0.2~1 part of plants essential oil to be dissolved in remaining food-grade ethanol, do not stop stirring and mixed until being completely dissolved and obtaining the 3rd
Close solution；
5）Above-mentioned first, second, and third mixed solution is stood respectively and is again well mixed three after 12-36 hours, Ran Houjia
Enter 15~50 parts of the plant extract hydrosol arranged in pairs or groups and used corresponding with plants essential oil, add appropriate amount of purified water trim, and add appropriate
PH adjusting agent causes the pH value of final mixed solution to be maintained between 6.0-7.0, and final mixed solution is stood into 10-15 days
Until fusion turns into the liquid of transparent and homogeneous completely；
（Two）The preparation of Ultramicro-powder suspension formulation, prepares the carrier, and the sterilization aqua and carrier are pressed into 2-3:1 ratio is mixed
And stir Ultramicro-powder suspension formulation is made.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610629342.9A CN106342946B (en) | 2016-08-02 | 2016-08-02 | A kind of air purifying and sterilizing agent and preparation method |
| PCT/CN2017/092904 WO2018024087A1 (en) | 2016-08-02 | 2017-07-14 | Air purification disinfectant and preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610629342.9A CN106342946B (en) | 2016-08-02 | 2016-08-02 | A kind of air purifying and sterilizing agent and preparation method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106342946A CN106342946A (en) | 2017-01-25 |
| CN106342946B true CN106342946B (en) | 2017-09-26 |
Family
ID=57843829
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610629342.9A Active CN106342946B (en) | 2016-08-02 | 2016-08-02 | A kind of air purifying and sterilizing agent and preparation method |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN106342946B (en) |
| WO (1) | WO2018024087A1 (en) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106342946B (en) * | 2016-08-02 | 2017-09-26 | 中山圣菲环保科技有限公司 | A kind of air purifying and sterilizing agent and preparation method |
| CN107853332A (en) * | 2017-09-20 | 2018-03-30 | 连云港柘达消毒科技有限公司 | A kind of environment-friendly high-efficiency disinfectant |
| CN108371883A (en) * | 2018-02-02 | 2018-08-07 | 河南师范大学 | It is a kind of to be used to remove air purifying spraying agent of indoor formaldehyde and preparation method thereof |
| CN108770890A (en) | 2018-07-16 | 2018-11-09 | 王婧宁 | A kind of air purifying composition of novel antiviral sterilizing function |
| CN109805038A (en) * | 2019-03-05 | 2019-05-28 | 天津中澳嘉喜诺生物科技有限公司 | A kind of Australia tea tree essential oil disinfection agent and its preparation method and application |
| CN110583710A (en) * | 2019-10-08 | 2019-12-20 | 宜宾学院 | Multifunctional bacteriostatic composition and preparation method and application thereof |
| CN110917815A (en) * | 2019-11-29 | 2020-03-27 | 陕西速源节能科技有限公司 | Preparation method of indoor air purifying agent |
| CN111297949A (en) * | 2020-03-19 | 2020-06-19 | 王鹏 | Essential oil mask and preparation method thereof |
| CN112274685A (en) * | 2020-11-05 | 2021-01-29 | 欧唯(广东)香氛科技有限公司 | Space fragrance essential oil and preparation method thereof |
| CN112640901A (en) * | 2020-12-30 | 2021-04-13 | 浙江永宁药业股份有限公司 | Composite synergistic disinfectant, preparation method and application |
| CN113828134B (en) * | 2021-09-23 | 2023-11-14 | 施凯西(广东)生物技术有限公司 | Negative ion air purifying liquid, preparation method and special production equipment |
| CN114342964A (en) * | 2021-12-21 | 2022-04-15 | 广东长康科技有限公司 | Bactericide and preparation method and application thereof |
| CN114208858A (en) * | 2021-12-24 | 2022-03-22 | 中国农业科学院都市农业研究所 | Plant extract mosquito-proof slow-release material and preparation method thereof |
| CN116267945B (en) * | 2023-02-07 | 2024-03-15 | 广西壮族自治区农业科学院 | Pesticide composition for preventing and treating gummy stem blight of melons |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1524585A (en) * | 2003-09-18 | 2004-09-01 | 上海交通大学 | All natural air freshener |
| CN1562380A (en) * | 2004-04-22 | 2005-01-12 | 上海交通大学 | Full natural liquid type air freshener |
| CN103212102B (en) * | 2013-04-24 | 2015-08-05 | 浙江绿岛科技有限公司 | Multifunctional air purifying agent and preparation method thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101884801B (en) * | 2009-05-12 | 2013-01-16 | 中国科学院植物研究所 | Air freshener and preparation method and application thereof |
| CN102038012A (en) * | 2010-12-21 | 2011-05-04 | 余媛媛 | Air disinfectant and preparation method thereof |
| CN105727337A (en) * | 2016-02-17 | 2016-07-06 | 广西大学 | Traditional Chinese medicine antimicrobial air freshener and preparation method thereof |
| CN106342946B (en) * | 2016-08-02 | 2017-09-26 | 中山圣菲环保科技有限公司 | A kind of air purifying and sterilizing agent and preparation method |
-
2016
- 2016-08-02 CN CN201610629342.9A patent/CN106342946B/en active Active
-
2017
- 2017-07-14 WO PCT/CN2017/092904 patent/WO2018024087A1/en active Application Filing
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1524585A (en) * | 2003-09-18 | 2004-09-01 | 上海交通大学 | All natural air freshener |
| CN1562380A (en) * | 2004-04-22 | 2005-01-12 | 上海交通大学 | Full natural liquid type air freshener |
| CN103212102B (en) * | 2013-04-24 | 2015-08-05 | 浙江绿岛科技有限公司 | Multifunctional air purifying agent and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN106342946A (en) | 2017-01-25 |
| WO2018024087A1 (en) | 2018-02-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN106342946B (en) | A kind of air purifying and sterilizing agent and preparation method | |
| CA2406558C (en) | Antimicrobial composition formulated with essential oils | |
| CN1883275B (en) | A botanical antibiotic and application thereof | |
| CN104336078A (en) | Chlorine-containing Chinese herbal medicine air disinfectant, and preparation method and application thereof | |
| CN106310326A (en) | Air freshener and preparation method thereof | |
| US10342840B2 (en) | Nanoparticulate titanium dioxide nanomaterial modified with functional groups and with citric extracts adsorbed on the surface, for the removal of a wide range of microorganisms | |
| CN106212551B (en) | Daily non-stimulated disinfectant of one kind and preparation method thereof | |
| CN101884801A (en) | Air freshener and preparation method and application thereof | |
| CN106234439B (en) | A kind of superbacteria antibiosis and sterilization agent and its preparation method and application | |
| CN106259509A (en) | A kind of natural plant disinfectant and preparation method thereof | |
| CN108935548A (en) | Environment friendly bacteriostatic air freshener and preparation method thereof | |
| CN103977443A (en) | Folium artemisiae argyi extract air freshener for air sterilization and mosquito repelling | |
| US20060075922A1 (en) | Controlled-acidity composition | |
| EP2399597B1 (en) | Disinfectant making air fresh and preparation method and use thereof | |
| CN111493097A (en) | Collective disinfectant for inhibiting viruses and pathogenic bacteria and preparation method thereof | |
| CN107873701A (en) | A kind of aerosol for expelling parasite, sterilizing and mite killing and preparation method thereof | |
| CN111109301A (en) | Composite disinfectant and preparation method and application thereof | |
| CN104430575B (en) | For the thimerosal and preparation method sterilized in ward | |
| KR101868127B1 (en) | Disinfecting agent using Thuja orientalis extract and its preparation method | |
| CN105012581A (en) | Fresh aloe antibacterial composite, application and preparing method of fresh aloe antibacterial composite | |
| CN107535540A (en) | A kind of antiseptic and preparation method thereof | |
| Sultana et al. | Antibacterial effect of aqueous neem (Azadirachta indica) leaf extract, crude neem leaf paste, and ceftriaxone against Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa | |
| CN107343865B (en) | Compound volatile oil and preparation method and application thereof | |
| CN105106278A (en) | Chinese herbal medicine sterilization and disinfection lotion and preparation method thereof | |
| CN104604963B (en) | Lotus leaf-corn stigma-sulfur mixture for bacteriostasis and preparation method and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |