CN102727693A - Compound propolis composition used for treating swine toxoplasmosis, and preparation method thereof - Google Patents
Compound propolis composition used for treating swine toxoplasmosis, and preparation method thereof Download PDFInfo
- Publication number
- CN102727693A CN102727693A CN2012102042103A CN201210204210A CN102727693A CN 102727693 A CN102727693 A CN 102727693A CN 2012102042103 A CN2012102042103 A CN 2012102042103A CN 201210204210 A CN201210204210 A CN 201210204210A CN 102727693 A CN102727693 A CN 102727693A
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- composition
- propolis
- swine toxoplasmosis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention relates to a compound propolis composition used for treating swine toxoplasmosis. The composition is prepared from mixed components of, by weight: 15-35 parts of propolis, 15-40 parts of antifebrile dichroa root, 15-45 parts of betelnutpalm seed, 15-35 parts of tangerine peel, 15-35 parts of Chinese thorowax root, 15-35 parts of balloonflower root, 15-45 parts of male fern rhizome, 15-35 parts of Chinese ephedra herb, 15-35 parts of epimedium, and 15-40 parts of licorice root. The composition provided by the invention is advantaged in reasonable formula, simple preparation, pure traditional Chinese composition and no pollution, no toxic or side effect, no drug residue, and substantial curative effect. As a result of clinical application, the composition has a special effect in treating swine toxoplasmosis.
Description
Technical field
The present invention relates to a kind of compound bee-glue composition of treating swine toxoplasmosis and preparation method thereof, belong to the animal field of medicaments, particularly a kind of compound bee-glue composition that is specifically designed to the treatment swine toxoplasmosis and preparation method thereof.
Background technology
Swine toxoplasmosis is called tokoplasmosis or toxoplasmosis again, is by toxoplasma infection animal and people and cause the protozoacide of infecting both domestic animals and human.Primary disease is a principal character with hyperpyrexia, breathing and neurological symptom, animal dead and pregnant animal miscarriage, stillborn fetus, fetal anomaly.
At present, this disease does not also have good Therapeutic Method, has only sulfa drugs that specially good effect is arranged, and other antibiotic are invalid, in case produce drug resistance, this disease is difficult to treatment; And also have drug residue, influence health.This disease gives that pig industry and people are healthy to cause very big threat.
Therefore research and develop a kind of treat swine toxoplasmosis and have no side effect, drug residue free, the specific medicament that produces that has no drug resistance be one of this field scientific research technical staff new problem anxious to be solved.
Summary of the invention
The objective of the invention is to overcome above-mentioned weak point, a kind of reasonable recipe, preparation simple, have no side effect, have no drug resistance generation, drug residue free are provided, effect obviously, is effectively treated compound bee-glue composition of swine toxoplasmosis and preparation method thereof.
Following for realizing the embodiment that above-mentioned purpose the present invention adopted: a kind of compound bee-glue composition of treating swine toxoplasmosis, by following component by weight mixed preparing form: propolis 15-35 part, Radix Dichroae 15-40 part, Semen Arecae 15-45 part, Pericarpium Citri Reticulatae 15-35 part, Radix Bupleuri 15-35 part, Radix Platycodonis 15-35 part, Rhizoma Dryopteris Crassirhizomatis 15-45 part, Herba Ephedrae 15-35 part, Herba Epimedii 15-35 part, Radix Glycyrrhizae 15-40 part.
Said various component optimum ratio amount is: 25 parts of propolis, 30 parts of Radix Dichroaes, 30 parts of Semen Arecaes, 25 parts of Pericarpium Citri Reticulataes, 25 parts of Radix Bupleuri, 25 parts of Radix Platycodoniss, 30 parts of Rhizoma Dryopteris Crassirhizomatiss, 25 parts in Herba Ephedrae, 25 parts of Herba Epimedii, 30 parts in Radix Glycyrrhizae.
A kind of method for preparing of treating the compound bee-glue composition of swine toxoplasmosis, carry out as follows:
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing propolis 15-35 part, Radix Dichroae 15-40 part, Semen Arecae 15-45 part, Pericarpium Citri Reticulatae 15-35 part, Radix Bupleuri 15-35 part by weight, mix 5-10 minute to even;
(3) take by weighing Radix Platycodonis 15-35 part, Rhizoma Dryopteris Crassirhizomatis 15-45 part, Herba Ephedrae 15-35 part, Herba Epimedii 15-35 part, Radix Glycyrrhizae 15-40 part by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
The medicinal property of each component is following:
Propolis: bitter, hot, cold, return spleen, lung, stomach warp, have anti-bacteria and anti-virus, antalgesic-antipruritic, promotion tissue regeneration, improve immunity, antiallergic oxidation, stop blooding, moisturize, the function of relieving cough and asthma, protection gastrointestinal mucosa.
Radix Dichroae: bitter, hot, cold, return lung, liver, heart channel, have the function of parasite killing, expectorant removing food stagnancy; Curing mainly protozoacide, the impaction of rumen, phlegm retention gathers etc.
Semen Arecae: bitter, hot, warm, return stomach, large intestine channel, have the function of anthelmintic, removing food stagnancy, circulation of qi promoting, diuretic; Cure mainly taeniasis, the impaction of rumen, dyspeptic abdominal distention, constipation, edema etc.
Pericarpium Citri Reticulatae: bitter, hot, warm, return lung, spleen channel, have the function of regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm; Cure mainly that appetite minimizing, stomachache, tripe are expanded, had loose bowels, productive cough due to phlegm-damp etc.
Radix Bupleuri: hot, bitter, be slightly cold, return liver, gallbladder, lung meridian, have the function of delivering with lining, elevate a turnable ladder yang-energy, dispersing the stagnated live-QI to relieve the stagnation of QI; Cure mainly cold, fever, alternate attack of chill and fever, insufficiency of the spleen chronic diarrhea, proctoptosis etc.
Radix Platycodonis: bitter, hot, flat, return lung meridian, have lung qi dispersing, eliminate the phlegm, the function of sore-throat relieving, evacuation of pus; Cure mainly cough with copious phlegm, laryngopharynx swelling and pain, lung abscess etc.
Rhizoma Dryopteris Crassirhizomatis: bitter, cold, return liver, stomach warp, have heat-clearing and toxic substances removing, cooling blood for hemostasis, anthelmintic function; Cure mainly epidemic disease flu, maculae caused by violent heat pathogen, sore swollen toxin, abdominal pain due to worm stagnation etc.
Herba Ephedrae: bitter, hot, warm, return lung, urinary bladder channel, have the function of the cold expelling that induces sweat, depressed lung-energy dispersing, inducing diuresis to remove edema; Cure mainly cough, affection of exogenous wind-cold, asthma, edema etc.
Herba Epimedii: sweet, hot, warm, return liver, kidney channel, have the function of kidney-replenishing, bone and muscle strengthening, wind-damp dispelling; Cure mainly that the waist hip is unable, rheumatic arthralgia etc.
Radix Glycyrrhizae: sweet, flat, return lung, the heart, spleen channel, have invigorating the spleen and replenishing QI, expelling phlegm for arresting cough and middle emergency, detoxifcation, coordinating the actions of various ingredients in a prescription, cushion toxicity, strong function; Cure mainly weakness of the spleen and stomach, cough with asthma, poisoning etc.
More than all flavor Chinese medicine according to the tcm theory compatible combination, to the paathogenic factor and the pathological change of swine toxoplasmosis, the effect of performance treating both the principal and secondary aspects of a disease.
The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixes more even; Pure Chinese medicine composition is pollution-free, no drug residue, and cost is low, and it is wide to draw materials, the curative effect highly significant.Theoretical theoretical according to motherland tradition Chinese veterinarian with the modern Chinese medicine pharmacology, optimize this ten kinds of medicines, and make them form pure Chinese powder medicine according to optimum ratio, clinical practice proves, specially good effect is arranged and has no side effect and drug resistance treating swine toxoplasmosis.And make livestock products reach nuisanceless requirement, satisfy the export standard of poultry product, guaranteed that effectively people's is healthy.
The specific embodiment
Below in conjunction with preferred embodiment, to details are as follows according to the specific embodiment provided by the invention:
Embodiment 1
A kind of compound bee-glue composition of treating swine toxoplasmosis and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing 150 parts of propolis, 150 parts of Radix Dichroaes, 150 parts of Semen Arecaes, 150 parts of Pericarpium Citri Reticulataes, 150 parts of Radix Bupleuri by weight, mix 5-10 minute to even;
(3) take by weighing 150 parts of Radix Platycodoniss, 150 parts of Rhizoma Dryopteris Crassirhizomatiss, 150 parts in Herba Ephedrae, 150 parts of Herba Epimedii, 150 parts in Radix Glycyrrhizae by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 2
A kind of compound bee-glue composition of treating swine toxoplasmosis and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing 250 parts of propolis, 200 parts of Radix Dichroaes, 300 parts of Semen Arecaes, 250 parts of Pericarpium Citri Reticulataes, 250 parts of Radix Bupleuri by weight, mix 5-10 minute to even;
(3) take by weighing 250 parts of Radix Platycodoniss, 300 parts of Rhizoma Dryopteris Crassirhizomatiss, 250 parts in Herba Ephedrae, 250 parts of Herba Epimedii, 300 parts in Radix Glycyrrhizae by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 3
A kind of compound bee-glue composition of treating swine toxoplasmosis and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing 350 parts of propolis, 400 parts of Radix Dichroaes, 450 parts of Semen Arecaes, 350 parts of Pericarpium Citri Reticulataes, 350 parts of Radix Bupleuri by weight, mix 5-10 minute to even;
(3) take by weighing 350 parts of Radix Platycodoniss, 450 parts of Rhizoma Dryopteris Crassirhizomatiss, 350 parts in Herba Ephedrae, 350 parts of Herba Epimedii, 400 parts in Radix Glycyrrhizae by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Clinical trial:
The clinical experiment animal selects for use 70-85 age in days, body weight at 25kg-35kg, and laboratory is diagnosed as the ill pig of swine toxoplasmosis.Ill pig is isolated raising separately, the complete feed of feeding, and be divided into 3 groups at random, and 30 every group, 3 groups of feeding environments are identical, and experiment was carried out 7 days altogether; The blank group is left intact, and the medicine matched group uses treatment with " bow that goes out looses " by specification; Chinese medicine composition group of the present invention can be with the ill pig of product feeding of the present invention, and a day dose is: per 100 gram present composition spices are fed every day 1-2 time for 230 kilograms; Oral back reaches the purpose of treatment disease through gastrointestinal absorption.Computational methods: mortality rate=dead animal number/experimental animal number * 100%, cure rate=healing number of animals/experimental animal number * 100%.Result's (testing the 7th day) when following table is the experiment end.
Table is the situation contrast of the present invention and other medicines treatment swine toxoplasmosis:
| Numbering | Group | Mortality rate % | Cure rate % | Symptom rate % is arranged during end |
| I | The blank group | 10.0 | 63.3 | 26.7 |
| II | The bow that goes out looses and organizes | 6.7 | 83.3 | 10.0 |
| III | Chinese medicine composition group of the present invention | 3.3 | 90.0 | 6.7 |
This clinical effectiveness is through statistical analysis, and present composition group is loose to organize with the bow that goes out and compared significant difference (P＜0.05) aspect the cure rate.
Safety testing:
Choose 10 of 70 age in days health pig; 5 times of spices according to the embodiment of the invention 1 made compositions RD were fed 10 days; During the medication; Health pig has no bad or Deviant Behavior performance, and the drinking-water of searching for food is normal, and it is not remarkable that weight increase and blank group (being not administration of health group) are compared difference.
Above-mentioned detailed description of compound bee-glue composition of this treatment swine toxoplasmosis and preparation method thereof being carried out with reference to embodiment; Be illustrative rather than determinate; Can enumerate out several embodiment according to institute's limited range; Therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.
Claims (3)
1. compound bee-glue composition of treating swine toxoplasmosis, it is characterized in that by following component by weight mixed preparing form: propolis 15-35 part, Radix Dichroae 15-40 part, Semen Arecae 15-45 part, Pericarpium Citri Reticulatae 15-35 part, Radix Bupleuri 15-35 part, Radix Platycodonis 15-35 part, Rhizoma Dryopteris Crassirhizomatis 15-45 part, Herba Ephedrae 15-35 part, Herba Epimedii 15-35 part, Radix Glycyrrhizae 15-40 part.
2. the compound bee-glue composition of treatment swine toxoplasmosis according to claim 1, it is characterized in that by following component by weight mixed preparing form: 25 parts of propolis, 30 parts of Radix Dichroaes, 30 parts of Semen Arecaes, 25 parts of Pericarpium Citri Reticulataes, 25 parts of Radix Bupleuri, 25 parts of Radix Platycodoniss, 30 parts of Rhizoma Dryopteris Crassirhizomatiss, 25 parts in Herba Ephedrae, 25 parts of Herba Epimedii, 30 parts in Radix Glycyrrhizae.
3. the method for preparing of the compound bee-glue composition of a treatment swine toxoplasmosis according to claim 1 and 2 is characterized in that carrying out as follows:
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing propolis 15-35 part, Radix Dichroae 15-40 part, Semen Arecae 15-45 part, Pericarpium Citri Reticulatae 15-35 part, Radix Bupleuri 15-35 part by weight, mix 5-10 minute to even;
(3) take by weighing Radix Platycodonis 15-35 part, Rhizoma Dryopteris Crassirhizomatis 15-45 part, Herba Ephedrae 15-35 part, Herba Epimedii 15-35 part, Radix Glycyrrhizae 15-40 part by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210204210.3A CN102727693B (en) | 2012-06-20 | 2012-06-20 | Compound propolis composition used for treating swine toxoplasmosis, and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210204210.3A CN102727693B (en) | 2012-06-20 | 2012-06-20 | Compound propolis composition used for treating swine toxoplasmosis, and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102727693A true CN102727693A (en) | 2012-10-17 |
| CN102727693B CN102727693B (en) | 2014-01-01 |
Family
ID=46984457
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210204210.3A Expired - Fee Related CN102727693B (en) | 2012-06-20 | 2012-06-20 | Compound propolis composition used for treating swine toxoplasmosis, and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102727693B (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104474416A (en) * | 2014-11-03 | 2015-04-01 | 青岛绿曼生物工程有限公司 | Swine toxoplasmosis treatment compound propolis composition and preparation method thereof |
| CN104645172A (en) * | 2013-11-20 | 2015-05-27 | 天津嘉瑞生物科技有限公司 | Traditional Chinese composition for treating porcine toxoplasmosis and preparation method thereof |
| CN105535051A (en) * | 2016-03-02 | 2016-05-04 | 江西傲新生物科技有限公司 | Pharmaceutical preparation for preventing and treating toxoplasmosis of pigs and preparation method of pharmaceutical preparation |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101647515A (en) * | 2009-06-26 | 2010-02-17 | 郑州后羿制药有限公司 | Chinese herbal growth promoter, preparation method and application thereof |
-
2012
- 2012-06-20 CN CN201210204210.3A patent/CN102727693B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101647515A (en) * | 2009-06-26 | 2010-02-17 | 郑州后羿制药有限公司 | Chinese herbal growth promoter, preparation method and application thereof |
Non-Patent Citations (2)
| Title |
|---|
| 张志远等: "《中药抗动物寄生虫病得研究进展》", 《河南畜牧兽医》, vol. 22, no. 8, 31 December 2001 (2001-12-31), pages 10 - 11 * |
| 戴永海: "《中兽医药防治畜禽传染病的应用研究》", 《中国畜牧兽医学会家畜内科学分会第七届代表大会暨学术研讨会论文集（下册）》, 31 December 2011 (2011-12-31), pages 883 - 884 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104645172A (en) * | 2013-11-20 | 2015-05-27 | 天津嘉瑞生物科技有限公司 | Traditional Chinese composition for treating porcine toxoplasmosis and preparation method thereof |
| CN104474416A (en) * | 2014-11-03 | 2015-04-01 | 青岛绿曼生物工程有限公司 | Swine toxoplasmosis treatment compound propolis composition and preparation method thereof |
| CN105535051A (en) * | 2016-03-02 | 2016-05-04 | 江西傲新生物科技有限公司 | Pharmaceutical preparation for preventing and treating toxoplasmosis of pigs and preparation method of pharmaceutical preparation |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102727693B (en) | 2014-01-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102961636B (en) | Pure traditional Chinese medicine composition for treating poultry infectious bursal disease and preparation method thereof | |
| CN102397335B (en) | Pure Chinese medicinal composition for treating poultry fatty liver haemorrhage syndrome and preparation method thereof | |
| CN102727693B (en) | Compound propolis composition used for treating swine toxoplasmosis, and preparation method thereof | |
| CN102670770A (en) | Compound propolis pure Chinese medicinal composition for treating white scour of piglets and preparation method thereof | |
| CN102488881B (en) | Compound propolis composition for promoting pig growth and fattening as well as its preparation method | |
| CN103585407B (en) | Chinese medicine composition for the treatment of pig infectious atrophic rhinitis and preparation method thereof | |
| CN102727769A (en) | Pure Chinese herbal composition for treating white scour of piglets | |
| CN102961526A (en) | Compound proplis composition for treating urate deposition syndrome of broiler chicken and preparation method thereof | |
| CN103479777B (en) | Pure Chinese medicine composition for the treatment of gosling plague and preparation method thereof | |
| CN102727694B (en) | Compound propolis composition used for treating broiler ascites syndrome, and preparation method thereof | |
| CN102397533B (en) | Compound propolis composition for treating livestock egg drop syndrome and preparation method thereof | |
| CN102600259B (en) | Complex propolis composition for treating eperythrozoon suis and preparation method thereof | |
| CN103599232B (en) | Pure Chinese medicine composition for the treatment of coccidiosis of domestic fowls and preparation method thereof | |
| CN103550705B (en) | The composition and method of making the same for the treatment of Infectious Tracheobroncheitis | |
| CN102397531B (en) | Compound propolis composition for treating duck plague and preparation method thereof | |
| CN103055090B (en) | Pure Chinese medicinal composition for treating fowl cholera and preparation method of pure Chinese medicinal composition | |
| CN102935139A (en) | Compound propolis composition for treating chronic gastroenteritis of livestock and preparation method of composition | |
| CN102499979B (en) | Compound propolis composition for treating dog and cat diarrhea and preparation method thereof | |
| CN102657808B (en) | Compound propolis combination for treating cattle and sheep hepatic fascioliasis and preparation method thereof | |
| CN102397510B (en) | Compound propolis composition for treating chicken Marek's disease and preparation method thereof | |
| CN102961516B (en) | Pure Chinese medicine composition for the treatment of duck viral hepatitis and preparation method thereof | |
| CN103550453B (en) | Promote Chinese medicine composition of poultry growing and fattening and preparation method thereof | |
| CN103877471A (en) | Traditional Chinese medicinal composition for treating porcine viral diarrhea and preparation method thereof | |
| CN102670761B (en) | Pure traditional Chinese medicine composition for treating infectious bursal disease of poultry and preparation method thereof | |
| CN103611032B (en) | The dyspeptic composition and method of making the same for the treatment of dog cat |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140101 Termination date: 20160620 |