CN102440943A - Composition for caring and improving aged or damaged skin - Google Patents
Composition for caring and improving aged or damaged skin Download PDFInfo
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- CN102440943A CN102440943A CN2011102447779A CN201110244777A CN102440943A CN 102440943 A CN102440943 A CN 102440943A CN 2011102447779 A CN2011102447779 A CN 2011102447779A CN 201110244777 A CN201110244777 A CN 201110244777A CN 102440943 A CN102440943 A CN 102440943A
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Abstract
The invention discloses a cosmetic composition for caring and improving aged or nutrient-deficient skin or skin subjected to environmental damage. The composition comprises nanogold, high-energy source and/or peptides for skin cell metabolism, and one or more antioxidants. The components have favorable coordinating actions, and can improve the skin in the aspects of visual appearance, physiological functions, clinical characteristics and biophysical features.
Description
Technical field
The present invention relates to cosmetic composition, said cosmetic composition comprises nanometer gold, is used for the high-energy source of skin cell metabolism and/or wins peptide class, one or more antioxidants.Can be used for nursing and improve aging, malnutrition or receive the skin of environmental nuisance, can improvement be provided in visual appearance, physiologic function, clinical characteristics and biophysics's characteristic aspect of skin.
Technical background
Gold is used for skin protection and comes from ancient Egypt the earliest, and spun gold is implanted the skin corium defying age, and in ancient Roman, the doctor treats dermatosis with gold; In the pharmacopeia on Chinese history, native gold has various medical value, and the holy Li Shizhen (1518-1593 A.D.) Compendium of Material Medica of Ming Dynasty's medicine has done to study in great detail most record to its property of medicine, consumption.Flourish youth's work " revise and enlarge with Chinese medicine and examine " of the pharmacists Junichiro Koizumi of Japan is also on the books.The 16 meeting of nineteen eighty-three The World Health Organization's food additive regulations committee (CCFA) (Hague, Detch meeting) formally classified native gold as the food additive scope, classifies A table the as No. 310.
Nanometer gold has very strong adsorption function to protein, DNA etc., and can not change the character of adsorbed material, and the antibiotic property of nano gold sol, safety, toxicity have been passed through FDA (Food and Drug Adminstration) (FDA) authentication.By extensive studies and application, nanometer gold can play the effect of carrying the active component Transdermal absorption to nanometer gold as the good pharmaceutical carrier of character, thereby improves the absorption of skin to effective ingredient.
Discover that nanometer gold has the promotion cell proliferation, the function that enhances metabolism more.The inventor also finds that nanometer gold all can promote cell proliferation to the human skin cell in the finite concentration scope, has dose dependent and time dependence, and on cell proliferation shows as the significance facilitation and along with the increase of time, promotes multiplication capacity to strengthen.
Along with age ageing, the visual appearance, physical characteristic and the physiological function that contact adverse environmental factors or malnutrition skin for a long time change, and are considered on the cosmetology not expected.Often show as clinically that pachylosis, drying, sensitivity and fragility increase, cutis laxa, elasticity reduce, wrinkle increases, atrophoderma, corium transparency increase and make skin shinny, but generally can keep its whole geometry graphical appearance, often is canescence.These are the hypometabolism with the aging of age all, contacts adverse environmental factors for a long time or malnutrition has confidential relation.
Preventing the skin aging and the wrinkle that goes down in advance is the eternal problem of cosmetics research and development.
Because the outermost horny layer of skin itself has as defence from external allotrylic barrier property physiological function; So just simply relevant functional components is fitted in the external agent; Be can not obtain abundant Transdermal absorption, can not show the original effect of this composition.Used Percutaneous absorption enhancers such as dimethyl sulfoxine, dimethyl formamide, dimethyl acetamide, methyl decyl sulfoxide in recent years, purpose is to improve the percutaneous absorbability of various materials.Yet these Percutaneous absorption enhancers do not provide satisfied Transdermal absorption facilitation effect, and because erythema etc. is appearred by force and sometimes in skin irritation on skin, so, be not desirable especially aspect its effect, safety, the use.
In order to improve the functional of functional type cosmetics, it is good and do not have a functional cosmetics compositions of negative interaction to need to continue development effectiveness.
Nanometer gold also has been used in the cosmetics, for example: Chinese patent: application number 200810045539.3 disclosed " a kind of method for preparing of eye-care cosmetic " has proposed a kind of prescription and method for preparing that contains the eye-care cosmetic of nanometer gold.
The inventor finds; Because nanometer gold self can promote the metabolism of skin; And can promote the Transdermal absorption of other functional components, nanometer gold, the compositions that is used for the high-energy source of skin metabolism and/or wins peptide class, one or more antioxidants are in nursing and improve aging, malnutrition or receive and show synergism characteristic aspect the skin of environmental nuisance.
Summary of the invention
The present invention is through providing a kind of cosmetic composition that contains nanometer gold, for nursing with improve aging, malnutrition or receive the skin of environmental nuisance that a kind of unique combination thing is provided.
Said compositions contains: nanometer gold, the high-energy source that is used for skin cell metabolism and/or victory peptide class, one or more antioxidants.Wherein with the form configuration of compositions by the beauty treatment mixture.
Nanometer gold is with the high-energy source that is used for skin cell metabolism and/or win peptide class and one or more antioxidant combination; When nanometer gold self promotes cell metabolism; Nanometer gold has also promoted the Transdermal absorption of other material in the compositions; And nanometer gold and be used for the high-energy source of skin cell metabolism and/or win between peptide class and antioxidant producing synergism, thereby produced beyond thought beneficial effect.
According to the present invention, said cosmetic composition comprises nanometer gold, and the particle size range of nanometer gold is 5nm to 100nm, preferred 5nm to 50nm, more preferably 10nm to 30nm.Preferably, adopting with the polyvinylpyrrolidone is protective agent, is the nano gold sol of the method preparation of Reducing agent reduction gold chloride with the sodium citrate, and the nanometer gold concentration of nano gold sol is 100 μ mol/L to 10mmol/L, preferred 200 μ mol/L to 1mmol/L.
In embodiment of the present invention, compositions comprises the weight 0.0001%-10% by said compositions, preferred 0.0005% to 0.1% nanometer gold.
Compositions of the present invention can be included in the cosmetic carrier.Cosmetic carrier can comprise emulsion, cream frost, washing liquid, solution, gel or ointment, or any other carrier well known by persons skilled in the art.In aspect concrete, emulsion can be emulsion oil-in-water or water-in-oil emulsion.Solution of the present invention can be, for example: aqueous solution or water-alcohol property solution.Anhydrous base material can be lip pomade or powder.
Aspect other indefiniteness, compositions of the present invention can be included in aging products or the humidification product, and perhaps being designed to provides in any product of benefit to skin.In the concrete aspect, compositions can be fit to during use use one day at least once, twice, three times, four times, five times or more times.Compositions can also be a chemical compatibility.
According to the present invention; Said compositions contains the high-energy source that is used for skin cell metabolism such as the wheat protein of lactobacillus ferment, hydrolysis, glycine, arginine and this type of methionine; The victory peptide class that said compositions contains is selected from: two victory peptides, palmitoyl tripeptide 3, four victory peptides, Wushengtai, six victory peptides, seven victory peptides, eight victory peptides, nine victory peptides or their mixture; One or more antioxidants that said compositions contains are selected from: nicotiamide, vitamin A and derivant thereof, vitamin E and derivant thereof, ascorbic acid, magnesium ascorbyl phosphate, sodium ascorbate, ascorbic acid polypeptide, ascorbyl dipalmitate, methyl silicane alcohol ascorbic acid, ascorbyl stearate, ascorbic acid tocopherol potassium phosphate, cysteine, tocopherol and derivant, ferulic acid, epicatechol gallate, gallateoctylester, propyl gallate, PGS, tocopherol acetas, Vitamin E linoleate, tocopheryl nicotinate, fertility succinate, rosmarinic acid, superoxide dismutase, catalase, glutathione peroxidase, metallothionein, Fructus Chaenomelis sulfydryl enzyme, coenzyme Q10 or their mixture.
This cosmetic composition can comprise the weight 0.01% to 30% by said compositions, preferred 0.1% to 9% high-energy source that is used for skin cell metabolism and/or victory peptide class; Compositions comprises the weight 0.05% to 20% by said compositions, one or more antioxidants of preferred 0.1 to 9%.
In claim and/or description, word " one, one " when " containing " logotype with term, it can refer to " one ", but also meet " one or more ", " at least one " and " one 's or greater than one " implication.
The present composition is used to improve skin vision outward appearance, physiologic function or the biophysics's characteristic that receives many factor affecting and change.Wherein said many factors are age ageing, long-term Exposure to Sunlight, adverse environment condition for example, such as pollutant, family apply some make up, disease pathological changes, smoking or underfed factor.Wherein the variation of said visual appearance comprises; For example; The appearance of microgroove and wrinkle, depression increase, loss of elasticity, fecundity forfeiture and the forfeiture of color and luster uniformity, textured, mottled pigmentation, its of the present invention these are done below further with others and are described in detail.
The A nanometer gold
Discover that nanometer gold has the promotion cell proliferation more; The function that enhances metabolism; The inventor also finds that nanometer gold also all can promote cell proliferation to the human skin cell in the finite concentration scope, has dose dependent and time dependence, and on cell proliferation shows as the significance facilitation and along with the increase of time; Promote multiplication capacity to strengthen; Nanometer gold does not influence cancerous cell simultaneously, and fibroblast in-vitro multiplication ability detection all ages and classes HSF's the age of duplicating life time and donor is negative correlation, and one-year-old its cells in vitro of every increase of donor age is duplicated life time and reduced for 0.2 generation.
Nanometer gold self can promote the metabolism of skin; Can promote the Transdermal absorption of other functional components, the high-energy of nanometer gold, skin metabolism source and/or the compositions that wins peptide class, one or more antioxidants are in nursing and improve aging, malnutrition or receive and show synergism characteristic aspect the skin of environmental nuisance.
B is used for the high-energy source of skin cell metabolism
In typical embodiment, described high-energy source comprises the lactobacillus ferment.In concrete embodiment, origin hang oneself phosphagen-derived molecules of microorganism of biotechnology modified in described high-energy source is formed.It is made up of wheat protein, glycine, arginine and the methionine of glycerol, lactobacillus ferment, hydrolysis.As embodiment, this energy source can trade name PHOSPHOVITAL
TMBe commercially available, on sale in French Si Dama company.This material provides the high-energy that is used for skin cell metabolism source.The working concentration of this material in prescription is more than 0.05% to 30% or 30%.
The C antioxidant
Antioxidant be one type can help to catch and in and free radical, thereby dispel one type of material of radical pair human body infringement.Radical reaction is to cause an old and feeble key factor, and scientist is the major reasons that cause aging, cell injury and degeneration through a large amount of experiment proof free-radical oxidations.Free radical is one type of harmful substance that can damage cell that is present in the body cell.In a kind of biological chain type course of reaction in body, the existence of free radical impels the interior old and feeble materials such as melanin, lipofuscin and ceroid that produce of skin histology.Biological itself have defence capability to free radical, but this ability increases along with the age and progressively goes down, the active attenuating.
The D cosmetic carrier
Compositions of the present invention all is effective in all types of cosmetic carrier.The indefiniteness embodiment of suitable cosmetic carrier comprises emulsion, cream, washing liquid; Solution (moisture and water-alcohol property), anhydrous base material (as, lip pomade and powder); Gel and ointment; Perhaps through other method or aforesaid any combination, can know like those skilled in the art institute, change and other suitable carriers apparent to those skilled in the art being suitable for uses in the present invention.
In preferred embodiments, cosmetic carrier is selected from emulsion oil-in-water, the encapsulate pearl in water-alcohol property solution or the anhydrous system.With regard to emulsion oil-in-water, this emulsion and composition and production method be well known in the art.Yet, importantly select the concentration and the combination of chemical compound and extract, combination is that chemical is compatible, and does not form complex and from finished product, precipitate.
The E beautification product
Compositions of the present invention can also be used for a lot of beautification products, includes but not limited to humidification cream, beneficial skin cream and washing liquid, gel, ointment, foundation cream, late frost, lip pomade, cleaning agent, toner, facial film and/or colored beautification product.The compositions first-selection is used for aging products, is used for facial and other body part, the most particularly stays the product on the skin.
F can combine other chemical compound and the reagent of use with the present invention
Compositions of the present invention can contain other beneficial agents and chemical compound, and for example, acute or chronic humidizer (comprises, for example; Wetting agent, occludent and the reagent that influences the natural humidification mechanism of skin), plant extract, antioxidant; Skin whitener (for example, hydroquinone), emollient, counter-stimulus; Vitamin, trace metal, antimicrobial, aromatic and/or dyestuff and coloring components.
1, humidizer
The indefiniteness embodiment of the humidizer that can in the present composition, use comprises aminoacid; Chondroitin sulfate, diglycerol, erythritol, fructose, glucose, glycerol, polyglycerine, dihydroxylic alcohols, 1; 2,6-hexanetriol, Mel, hyaluronic acid, hydrogenated honey, hydrogenated starch hydrolysate, inositol, lactose, maltose alcohol, maltose, mannitol, the natural humidification factor, PEG-15 butanediol, polyglycereol sorbitol ester, 2-pyrrolidone-5-carboxylic acid's salt, potassium PCA, propylene glycol, D-Glucuronic acid sodium salt, sodium PCA, sorbitol, sucrose, trehalose, urea and xylitol.
Other embodiments include acetylated lanolin, acetylated lanolin alcohols, acrylates / C10-C30 alkyl esters of acrylic acid crosslinked polymer, acrylate copolymer, alanine, algae extract, Aloe vera, Aloe vera extract, Aloe vera gel, pharmaceutical marshmallow extract, aluminum starch octenyl succinate, aluminum stearate, almond oil, arginine, arginine aspartate, arnica extract, ascorbic acid , ascorbyl palmitate operator, aspartic acid, avocado oil, barium sulfate, barrier permeability sheath esters, alcohol, beeswax, behenyl alcohol, β-sitosterol, birch bark extract , borage extract, 2 - bromo - 2 - nitro-1,3 - diol, Ruscus extract, butylene glycol, calendula extract, calendula oil, candelilla wax, vegetable oil, caprylic / capric acid triglyceride, cardamom oil, carnauba wax, carrageenan, carrot oil, castor oil, ceramides, ceresin, cetyl / stearyl alcohol ethoxylates -5, whale Wax / stearyl ether, polyoxyethylene-12 cetyl / stearyl alcohol ethoxylates -20 octanoate, cetyl / stearyl ester, polyoxyethylene cetyl ether, -20, polyoxyethylene cetyl -24 ethers, vinyl esters of cetyl alcohol, cetyl octanoate, cetyl palmitate, chamomile oil, cholesteryl esters, cholesteryl hydroxystearate, citric acid, subdural sage oil, cocoa butter, coconut caprylate / caprate, coconut oil, collagen, collagen amino acids, corn oil, fatty acids, decyl oleate, dextrin, disazo Lee urea, polyethylene and dimethicone copolyols, polydimethylsiloxane alcohol, dioctyl adipate, dioctyl succinate, dipentaerythritol hexa caprylate / caprate six, DMDM hydantoin, erythritol, ethoxycarbonyl Kiel Gan alcohol, ethyl Ayumi, blue eucalyptus oil, evening primrose oil, fatty acids, gelatin, large root geranium oil, glucosamine, glucose glutamate, glutamic acid, glycerol polyoxyethylene -26, glycerin hydroxy stearate, glycerol monolaurate, glycerol, glyceryl distearate, glyceryl hydroxystearate, glyceryl linoleate, glyceryl myristate, glyceryl with ester, glycerol stearate, glycerol stearate SE, glycine, glycol stearate, glycol stearate SE, glucose amino glycans, grape seed oil, hazelnut oil, ethylene glycol, honey, hyaluronic acid, hybrid safflower oil, hydrogenated palm glycerides, hydrogenated palm kernel oil, hydrogenated soybean oil, hydrogenated tallow glyceride, hydrogenated vegetable oil, hydrolyzed collagen, hydrolyzed elastin, hydrolyzed glucose amino glycans, hydrolyzed keratin, hydrolyzed soy protein , hydroxylated lanolin, strong proline, imidazoline urea, iodopropynyl butyl amine acid, isocetyl stearate, stearyl cetyl stiff isobutyl acrylate, isodecyl oleate, isostearyl isopropyl palmitate, isopropyl lanolin, isopropyl myristate, isopropyl palmitate, isopropyl stearate, isostearyl amide DEA, isostearic acid, isostearyl lactate esters, isostearyl pivalate, jasmine oil, jojoba oil wood, seaweed, rock chestnut kernel oil, lanolin alcohol ethoxylates -16, lanolin alcohol ethoxylates -10 acetate, lanolin , lanolin acid, lanolin alcohol, lanolin oil, lanolin wax, lavender oil, lecithin, lemon oil, linoleic acid, linolenic acid, kernel oil, magnesium stearate, magnesium sulfate, maltitol, chamomile oil, methyl glucose sesquistearate, methyl silanol PCE, microcrystalline wax, mineral oil, mink oil, Mortierella oil, myristyl lactate, myristyl myristate, myristyl propionate, neopentyl glycol dicaprylate / dicaprate, octyldodecanol, octyldodecyl myristate, octyldodecyl stearoyl stearate, octyl hydroxystearate , octyl palmitate, octyl salicylate, octyl stearate, oleic acid, olive oil, palmitic acid, pantethine, panthenol, paraffin, peach kernel oil, peanut oil, PEG-8 C12-18 ester, PEG- 15 coconut amine, PEG-150 distearate, PEG-60 hydrogenated castor oil, PEG-20 methyl glucose sesquistearate, PEG40 high sorbitan monooleate, PEG-5 soy sterol alcohols, PEG-10 soy alcohol, PEG-2 stearate, PEG-8 stearate, PEG-20 stearate, PEG-32 stearate, PEG-40 stearate, PEG-50 Hard fat acid esters, PEG-100 stearate, PEG-150 stearate, pentadecalactone, peppermint oil, petrolatum, phospholipids, polyamino sugar condensate, poly-glycerol-3 - diisostearate esters, Polyquaternium -24, polyoxyethylene sorbitan 20, polyoxyethylene sorbitan 40, polyoxyethylene sorbitan 60, polyoxyethylene sorbitan 80, polyoxyethylene sorbitan vinyl ether 85, potassium myristate, potassium palmitate, potassium sorbate, potassium stearate, propylene glycol, propylene glycol dicaprylate / dicaprate, propylene glycol octyl acetate, propylene glycol dipelargonate, propylene glycol laurate esters, propylene glycol stearate, propylene glycol stearate SE, polyvinyl pyrrolidone, pyrrole pigment dipalmitate, quaternary ammonium -15, di hydrogenated tallow dimethyl ammonium chloride and the reaction of hectorite product, quaternary ammonium -22, retinol palmitate, retinol acetate, 2 bran oil, RNA, rosemary oil, rose oil, safflower oil, rat tail oil, salicylic acid, sandalwood oil, serine, serum protein , sesame oil, shea butter, silk powder, sodium chondroitin sulfate, hyaluronic acid, sodium lactate, sodium palmitate, sodium polyglutamate, sodium stearate, soluble collagen, sorbic acid, sorbitan laurate, sorbitan monooleate, sorbitan monopalmitate, sorbitan sesquioleate, sorbitan stearate, sorbitol, soybean oil, sphingolipids, squalane, squalene, hard amide lipid MEA-stearate, stearic acid, stearyl glycyrrhetinate esters, stearyl heptanoate, stearyl stearate, sunflower seed oil, sweet almond oil, synthetic beeswax, tocopherol, tocopherol acetate, tocopherol linoleate, pivalic acid, tridecyl stearate, tridecyl, triethanolamine, glyceryl stearate, wheat germ oil, and clothing-oil, or a mixture thereof.
2, plant extract
The indefiniteness embodiment of the plant extraction/extracting solution that can in cosmetic composition of the present invention, use comprise extraction/extracting solution, Radix Glycyrrhizae extraction/extracting solution, Semen Litchi extraction/extracting solution, Semen Coicis extraction/extracting solution, Semen Vitis viniferae extraction/extracting solution, red Punica granatum L. extraction/extracting solution, Semen Ginkgo extraction/extracting solution, Fructus Chaenomelis ferment extraction/extracting solution, Spica Prunellae extraction/extracting solution, Flos Chrysanthemi Indici extraction/extracting solution, Ganoderma extraction/extracting solution, Herba Portulacae extraction/extracting solution, Folium Ginkgo extraction/extracting solution, Radix Scutellariae extraction/extracting solution, Radix Gentianae extraction/extracting solution, Australia Fructus Fragariae Ananssae extraction/extracting solution, honey peach extraction/extracting solution, lemonweed leaves of plants extraction/extracting solution, Fructus Mali pumilae extraction/extracting solution, Rhizoma Dioscoreae extraction/extracting solution, Rosehips extraction/extracting solution, Radix Angelicae Sinensis extraction/extracting solution, Herba Centellae extraction/extracting solution, green tea extraction/extracting solution, Flos Matricariae chamomillae extraction/extracting solution, Herba Taraxaci extraction/extracting solution, Fructus Ananadis comosi extraction/extracting solution, Bulbus Cardiocrini Cathayani extraction/extracting solution, Folium Artemisiae Argyi extraction/extracting solution, Radix et Caulis Opuntiae Dillenii extraction/extracting solution, Radix Hamamelidis Mollis extraction/extracting solution, Cortex Mori extraction/extracting solution, Gherkin extraction/extracting solution, seaweed extract/extracting solution, Radix Paeoniae Alba extraction/extracting solution, Herba Saussureae Involueratae extraction/extracting solution, Herba Leonuri extraction/extracting solution, Radix Puerariae extraction/extracting solution, Semen Castaneae extraction/extracting solution, green tea extraction/extracting solution, bodhi leaves and/or bark extraction/extracting solution, the marigold flower extraction/extracting solution of preferred Folium Aloe, bashfully blade of grass and/or skin extraction/extracting solution, Folium olive and/or fruit extraction/extracting solution, Radix Ginseng extract extraction/extracting solution, Herba Plantaginis extract extraction/extracting solution, propolis extraction/extracting solution, leaf of Herba Rosmarini Officinalis extraction/extracting solution, sage extraction/extracting solution, fly water Ji extraction/extracting solution; Til seed extraction/extracting solution, mandarin orange skin extraction/extracting solution, Testa Tritici and/or Fructus Tritici aestivi extraction/extracting solution, Herba bromi japonici plumule extraction/extracting solution; Or their mixture; More preferably extraction/the extracting solution of Rosehips, green tea extraction/extracting solution, Semen Vitis viniferae extraction/extracting solution, or their mixture.According to the present invention, cosmetic composition can comprise the weight 0.0001% to 2% by said compositions, and is preferred 0.001% to 0.5%, and more preferably additional plant extraction/extracting solution of 0.002% to 0.15%.
3, can combine other chemical compound and the reagent of use with the present invention
Other chemical compound that can in the present composition, use and the indefiniteness embodiment of reagent comprise skin whitener (for example: kojic acid, hydroquinone, ascorbic acid and derivant, retinoid and derivant thereof); Vitamin (for example: vitamin D, E, A, K, C), trace metal (for example: zinc, calcium and selenium), counter-stimulus (for example: allantoin, peanut extract, antiinflammatory); Dyestuff and coloring components (for example, No. four indigo plants of D&C, No. five, D&C is green, the D&C orange; D&C17 number red, and D&C33 number red, No. two purples of D&C, D&C10 Huang; D&C11 Huang and DEA-cetyl phosphate ester), and antiseptic (for example: Butylated hydroxyanisole), emollient (that is: organic ester, fatty acid; Lanoline and derivant thereof, plant and animal oil & fat, and diglyceride and triglyceride), and natural and synthetical aromatic.
In addition, can produce prevention,, include but not limited to p-Hydroxybenzoate (for example, p-Hydroxybenzoate, methaform, phenol, sorbic acid or their compositions) like various antibacteriums and antifungal to microbiological effect through antiseptic.
Preferred embodiment
The not homophase (A, B, C, D, E) that compositions according to the present invention comprises compositions below has been detailed, has mixed the embodiment that each obtains final products mutually through heating and/or being cooled to proper temperature.
The embodiment 1 nourishing late frost of whitening
Step: under the state that appropriateness stirs, heat respectively A mutually with B to 65 ℃, after stirring with B be added to A mutually in and the continuation stirring until gained mixture mix homogeneously.Then said mixture is cooled to 50 ℃ and C is added to, continues to be cooled to 40 ℃ and add the D phase, add the E phase subsequently, be stirred to mix homogeneously, be cooled to 35 ℃.
Embodiment 2 crease-resistant easypro eye creams alive
Step: under the state that appropriateness stirs, heat respectively A mutually with B to 65 ℃, after stirring with B be added to A mutually in and the continuation stirring until gained mixture mix homogeneously.Then said mixture is cooled to 50 ℃ and C is added to, continues to be cooled to 40 ℃ and add the D phase, add the E phase subsequently, be stirred to mix homogeneously, be cooled to 35 ℃.
Embodiment 3 crease-resistant moisturizers
Step: under the state that appropriateness stirs; Heat respectively A mutually with B to 65 ℃, after stirring with B be added to A mutually in and the continuation stirring until gained mixture mix homogeneously, then the gained mixture is cooled to 50 ℃ and C is added to; Continue to be cooled to 40 ℃ and add the D phase; Add the E phase subsequently, be stirred to mix homogeneously, be cooled to 35 ℃.
Instance 4 cosmetic water
Step: under the state that appropriateness stirs, heat respectively A mutually with B to 65 ℃, after stirring with B be added to A mutually in and continuation stirring gained mixture until mix homogeneously.Then said mixture is cooled to 40 ℃ and C is added to, is stirred to mix homogeneously, be cooled to 35 ℃.
Instance 5 elite
Step: under the state that appropriateness stirs, heat respectively A mutually with B to 65 ℃, after stirring with B be added to A mutually in and continuation stirring gained mixture until mix homogeneously.Then said mixture is cooled to 50 ℃ and C is added to.The gained mixture continues to be cooled to 40 ℃ and add the D phase, adds the E phase subsequently, is stirred to mix homogeneously, is cooled to 35 ℃.
Although illustrative embodiment of the present invention has been enclosed in above description, should be understood that certainly those skilled in the art obviously can carry out various improvement.
Claims (17)
1. compositions comprises:
A. nanometer gold;
B. be used for the high-energy source of skin metabolism and/or win the peptide class; With
C. one or more antioxidants.
2. compositions according to claim 1, the particle size range of nanometer gold is 5nm to 100nm in the wherein said compositions, preferred 5nm to 50nm, more preferably 10nm to 30nm.
3. compositions according to claim 2, to come from concentration be 100 μ mol/L to 10mmol/L to nanometer gold in the wherein said compositions, the nano gold sol of preferred 200 μ mol/L to 1mmol/L.
4. compositions according to claim 1, wherein said compositions is included in the cosmetic carrier.
5. compositions according to claim 4, wherein said cosmetic carrier comprise emulsion, cream, washing liquid, solution, anhydrous base material, gel or ointment.
6. compositions according to claim 5, wherein said emulsion are oil-in-water or water-in-oil emulsion.
7. compositions according to claim 5, wherein said solution are aqueous solution or water-alcohol solution.
8. compositions according to claim 1, wherein said compositions are included in aging products or humidification product or the maintenance product of whitening.
9. compositions as claimed in claim 4, wherein said compositions are applicable to one day during use and use at least once.
10. compositions as claimed in claim 4, wherein said compositions uses at least twice during use.
11. compositions according to claim 1, the high-energy source of wherein said skin metabolism comprises wheat protein, glycine, arginine and the methionine of glycerol, lactobacillus ferment, hydrolysis.
12. compositions according to claim 1, wherein said victory peptide class is selected from: two victory peptides, palmitoyl tripeptide 3, four victory peptides, Wushengtai, six victory peptides, seven victory peptides, eight victory peptides, nine victory peptides, or their mixture.
13. compositions according to claim 1; Wherein said one or more antioxidants are selected from: nicotiamide, vitamin A and derivant thereof, vitamin E and derivant thereof, ascorbic acid, magnesium ascorbyl phosphate, sodium ascorbate, ascorbic acid polypeptide; Ascorbyl dipalmitate, methyl silicane alcohol ascorbic acid, ascorbyl stearate, ascorbic acid tocopherol potassium phosphate, cysteine, tocopherol and derivant thereof, ferulic acid, epicatechol gallate, gallateoctylester, propyl gallate, PGS, tocopherol acetas, Vitamin E linoleate, tocopheryl nicotinate, fertility succinate, rosmarinic acid, superoxide dismutase, catalase, glutathione peroxidase, metallothionein, Fructus Chaenomelis sulfydryl enzyme, coenzyme Q10, or their mixture.
14. compositions as claimed in claim 1 is characterized in that compositions comprises the weight 0.0001%-10% by said compositions, preferred 0.0005% to 0.1% nanometer gold.
15. compositions as claimed in claim 14 is characterized in that compositions comprises the weight 0.01% to 30% by said compositions, the high-energy source of preferred 0.1% to 9% skin cell metabolism and/or victory peptide class.
16., it is characterized in that compositions comprises the weight 0.05% to 20% by said compositions, one or more antioxidants of preferred 0.1% to 9% like the described compositions of power claim 15.
17. compositions as claimed in claim 16, wherein said compositions are to be used for nursing and to improve aging, malnutrition or receive environmental nuisance skin.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310455248.2A CN103479551B (en) | 2011-08-25 | 2011-08-25 | Cosmetic water and preparation method |
| CN 201110244777 CN102440943B (en) | 2011-08-25 | 2011-08-25 | Composition for caring and improving aged or damaged skin |
| CN201310455371.4A CN103479552B (en) | 2011-08-25 | 2011-08-25 | Crease-resistant easypro eye cream alive and preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110244777 CN102440943B (en) | 2011-08-25 | 2011-08-25 | Composition for caring and improving aged or damaged skin |
Related Child Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310455371.4A Division CN103479552B (en) | 2011-08-25 | 2011-08-25 | Crease-resistant easypro eye cream alive and preparation method |
| CN201310455248.2A Division CN103479551B (en) | 2011-08-25 | 2011-08-25 | Cosmetic water and preparation method |
| CN201310455399.8A Division CN103479553B (en) | 2011-08-25 | 2011-08-25 | Essence and preparation method |
| CN201310455902.XA Division CN103479554B (en) | 2011-08-25 | 2011-08-25 | Whitening and nourishing night cream and preparation method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102440943A true CN102440943A (en) | 2012-05-09 |
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Also Published As
| Publication number | Publication date |
|---|---|
| CN103479552A (en) | 2014-01-01 |
| CN103479551A (en) | 2014-01-01 |
| CN102440943B (en) | 2013-09-11 |
| CN103479552B (en) | 2015-10-21 |
| CN103479551B (en) | 2015-10-21 |
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