CN107157798A - It is a kind of that there is the hormonal skin of face that is used for for releasing again change lead function to arrange the logical composition repaired - Google Patents

It is a kind of that there is the hormonal skin of face that is used for for releasing again change lead function to arrange the logical composition repaired Download PDF

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CN107157798A
CN107157798A CN201710437850.1A CN201710437850A CN107157798A CN 107157798 A CN107157798 A CN 107157798A CN 201710437850 A CN201710437850 A CN 201710437850A CN 107157798 A CN107157798 A CN 107157798A
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parts
skin
face
extract
deoxidation
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简经红
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Changsha Seal And Win Commodity Trading Co Ltd
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Changsha Seal And Win Commodity Trading Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66Enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63Steroids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86Polyethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
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  • Microbiology (AREA)
  • Mycology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Cosmetics (AREA)

Abstract

The present invention relates to a kind of there is the hormonal skin of face that is used for for releasing again change lead function to arrange the logical composition repaired, it is made up of following raw material according to shown weight ratio, 5~8 parts of deoxidation sulfydryl enzyme, 15~25 parts of active matter, 20~30 parts of polyalcohol, 20~30 parts of glycerine, 3~5 parts of saualane of synthesis, 1~3 part of tocopherol acetate, 1~3 part of cetostearyl alcohol, 1~3 part of allantoin, 10~15 parts of Butyrospermum parkii fruit fatty oil, plus deionized water is to 100 parts.The invention further relates to the specific preparation method of said composition.The present invention nourishes auxiliary material using Traditional skin, organically combine deoxidation sulfydryl enzyme, active matter, three kinds of independent activities function formulas of polyalcohol, effectively repair the steroids destruction that existing cosmetics are produced to skin of face, and lead, the mercury heavy metal toxin of pore hair follicle are discharged, eliminate accumulation and penetrate into, so as to reach effect that is comprehensive, comprehensively repairing skin of face.

Description

It is a kind of that there is the hormonal skin of face that is used for for releasing again change lead function to arrange the logical group repaired Compound
Technical field
The present invention relates to a kind of skin of face remediation composition, more particularly to one kind can the row of reparation it is logical because using existingization Cosmetic and produce facial hormone sexual stimulus and the composition of heavy metal poisoning and preparation method thereof.
Background technology
Emphasis with modern society people to self-image, cosmetics are generally connect by numerous women and part male By and routine use, but to form hormone face still unaware for the face of quite a few user, or is mistakenly considered common It is allergic general red, and continue voluntarily to smear various OTC ointment with kith and kin's suggestion by rule of thumb, such ointment is generally amcinonide Cream, although short-period used can take a favorable turn presentation, but then can only make symptom more serious.Hormone face belongs to the one of acne medicamentosa Kind, it is referred to as hormonal acne, is because the beauty and make-up of the either prolonged hormone abuse ointment of interruption or hormone in secret Product, cause a kind of severe skin disease caused by the toxic side effect of hormone, and it is different from common skin sensitivity or allergy, can be tight The cutaneous eubolism of weight, damages the normal physiological structure of skin, not only brings in the treatment to patient very big tired Disturb, it is often more important that its body and mind to patient causes larger burden, its most substantially, be also an ill maximum feature just It is the breaking-out of the state of an illness again and again, cardinal symptom has the expansion of (1) tiny blood vessels diffusivity, the skin especially after the stimulation such as heat to the cold Skin is rubescent, itches, send out and rise;(2) acne rosacea sample dermatitis, acne sample dermatitis, eczema, fuel-displaced serious;(3) skin early ageing, wrinkles It is line, relaxation, pore group big, skin water shortage, coarse;(4) red blood trace on face, thinning of skin, resistance declines;(5) fine hair it is thicker, Become many etc..In addition, widely applying the heavy metal such as mercury and lead in existing quick whitening product, it can play bleaching nti-freckle to skin Effect, can take effect rapidly in a short time, thus many consumers gone after like a flock of ducks for " effect " without carefully distinguish with The harm for understanding this chemical substance is just blindly used, and irremediable damage is caused to oneself skin and health.Lead, mercury It is another skin killer in addition to glucocorticoid.Lead and mercury content is exceeded can cause skin slow poisoning syndrome, Skin is set to become easily allergy, Accumulation of heavy metals destroys the normal physiological structure of skin, and the final skin pigment for producing exception sinks , melanosis occur.Its main influence on body is that heavy metal can cause slow poisoning, including liver kidney to be damaged in the deposition of skin Wound, trembles, hypomnesia, the neurological symptom such as vision, auditory function decline, causes skeletal muscle and bone tissue to damage, part Beauty parlor is the psychology for catering to customer's quick-acting beauty, the frequent exceeded use mercuride in cosmetics, to prove oneself to produce Product possess so-called " rapid ", the effect of " efficient ", ultimately result in spreading unchecked for corticosteroid dermatitis, customer suffers untold misery.
The content of the invention
The technical problem to be solved in the present invention is how to overcome the drawbacks described above of prior art to have to release there is provided one kind and change again The hormonal skin of face that is used for of lead function arranges the logical composition repaired.
In order to solve the above technical problems, the present invention's there is the hormonal skin of face that is used for for releasing again change lead function to arrange logical repair Multiple composition is made up of following raw material according to shown weight ratio, 5~8 parts of deoxidation sulfydryl enzyme, 15~25 parts of active matter, many First 20~30 parts of alcohol, 20~30 parts of glycerine, 3~5 parts of saualane of synthesis, 1~3 part of tocopherol acetate, cetostearyl alcohol 1~3 Part, 1~3 part of allantoin, 10~15 parts of Butyrospermum parkii fruit fatty oil, plus deionized water is to 100 parts.
As being further elaborated with, the deoxidation sulfydryl enzyme is mixed by the major ingredient and auxiliary material of following parts by weight, 6- Purinethol -2 ' 10 parts of-deoxyribonucleoside, 2 parts of papain, 4 parts of niacinamide, 4 parts of silandiol salicylate, natural fat 1 part of alcohol.The deoxidation sulfydryl enzyme main component is Ismipur -2 '-deoxyribonucleoside, from the limited public affairs of the U.S. logical sequence biotechnology in Dalian Department buys, and coordinates obtained deoxidation sulfydryl enzyme with auxiliary material, has reduction for steroid dependent dermatitis, is repaiied with very strong Renaturation, can repair skin in damaged condition, and dependence of the skin to hormone is blocked from root, make flesh with the principle of " being repaired in row " Skin recovers original penetrating health again.
As being further elaborated with, the active matter is mixed by following raw material according to shown weight ratio, Chinese holly 3 parts of Qi extract, 2 parts of eucommia ulmoides extracts, smooth 1 part of fruit elm chloroxylon swietenia bark extract, 2 parts of Schisandra fruit extract, the Radix Astragali are carried Take 2 parts of thing, 1 part of the bark of official magnolia bark extract, 2 parts of tea extract, 1 part of dipotassium glycyrrhizinate, 1 part of camomile extract, chlorella 2 parts of extract, 2 parts of Lupinus albus protein fermentation product, -10.25 parts of oligopeptides, -30.25 parts of oligopeptides, -50.25 parts of oligopeptides.Activity Thing has in the composition releases change lead nourishing effect again, mops up lead and mercury, cell repair is carried out while excluding release heavy metal, The pure natural plant ingredients extracted furthermore with biotechnology can lift immunity and metabolism.
As being further elaborated with, the polyalcohol is mixed by following raw material according to shown weight ratio, second 3 parts of glycol, 2 parts of methyl propanediol, 1 part of propane diols, 2 parts of DPG, 2 parts of butanediol, 3 parts of sorbierite, 1 part of polyethylene glycol. Polyalcohol plays the net skin effect of polyoxy in the composition, improves the metabolic capability of skin, and hormone mediates the factor heavy inside skin Long-pending hormone rubbish metabolism is fallen
As optimization formula ratio, it is made up of following raw material according to shown weight ratio, 7 parts of deoxidation sulfydryl enzyme, activity 20 parts of thing, 25 parts of polyalcohol, 25 parts of glycerine, 4 parts of saualane of synthesis, 2 parts of tocopherol acetate, 2 parts of cetostearyl alcohol, allantoin 2 parts, 13 parts of Butyrospermum parkii fruit fatty oil, plus deionized water is to 100 parts.
The preparation method that this antihormones releases the logical remediation composition of weight skin of face row comprises the following steps,
Step (1):The active matter, deionized water are mixed and inserted in kettle, 75~85 DEG C are heated to;
Step (2):Polyalcohol, glycerine, synthesis saualane, tocopherol acetate, cetostearyl alcohol, Butyrospermum parkii fruit fatty oil Mixing is inserted in oil cauldron, is heated to 65~75 DEG C;
Step (3):Step (1) resulting solution and step (2) resulting solution are inserted and mixed and emulsifying in emulsification pot 10min, gained emulsion is cooled to 36~38 DEG C, deoxidation sulfydryl enzyme and allantoin, stirs 10min;
Step (4):6~12h is stood after discharging, is added after preservative, filling and package is produced.
As prioritization scheme, the preservative described in step (4) is pressed by Metagin vinegar, Phenoxyethanol, double imidazolidinyl urea According to 1:1:2 weight ratio mixing.
A kind of antihormones of the present invention releases the logical remediation composition of weight skin of face row, and auxiliary material is nourished using Traditional skin, organic With reference to deoxidation sulfydryl enzyme, active matter, three kinds of independent activities function formulas of polyalcohol, existing cosmetics are effectively repaired to facial skin The steroids destruction that skin is produced, and discharge, eliminate accumulation and penetrate into lead, the mercury heavy metal toxin of pore hair follicle, so as to reach Effect that is comprehensive, comprehensively repairing skin of face.
Embodiment
Embodiment 1:
Formula:8 parts of deoxidation sulfydryl enzyme, 15 parts of active matter, 30 parts of polyalcohol, 20 parts of glycerine, 5 parts of saualane of synthesis, fertility 1 part of phenol acetic acid esters, 3 parts of cetostearyl alcohol, 1 part of allantoin, 15 parts of Butyrospermum parkii fruit fatty oil, plus deionized water is to 100 parts.It is described Deoxidation sulfydryl enzyme is mixed by the major ingredient and auxiliary material of following parts by weight, Ismipur -2 ' 10 parts of-deoxyribonucleoside, pawpaw egg White 2 parts of enzyme, 4 parts of niacinamide, 4 parts of silandiol salicylate, 1 part of natural fatty alcohol.The deoxidation sulfydryl enzyme main component is Ismipur -2 '-deoxyribonucleoside, from Dalian, Mei Lun Bioisystech Co., Ltd buys, and coordinates obtained deoxidation mercapto with auxiliary material Base enzyme, has reduction for steroid dependent dermatitis, with very strong prosthetic, can repair skin in damaged condition, from root Dependence of the skin to hormone is blocked on source, skin is recovered original penetrating health again with the principle of " being repaired in row ".Institute Active matter is stated to be mixed according to shown weight ratio by following raw material, it is 3 parts of wolfberry fruit extract, 2 parts of eucommia ulmoides extracts, smooth 1 part of fruit elm chloroxylon swietenia bark extract, 2 parts of Schisandra fruit extract, 2 parts of Astragalus Root P.E, 1 part of the bark of official magnolia bark extract, tealeaves 2 parts of extract, 1 part of dipotassium glycyrrhizinate, 1 part of camomile extract, 2 parts of chlorella extract, Lupinus albus protein fermentation product 2 Part, -10.25 parts of oligopeptides, -30.25 parts of oligopeptides, -50.25 parts of oligopeptides.Active matter has to release in the composition changes lead nourishing work again With, lead and mercury are mopped up, excludes and carries out cell repair while discharging heavy metal, the pure natural plant extracted furthermore with biotechnology Thing composition can lift immunity and metabolism.The polyalcohol is mixed according to shown weight ratio by following raw material and made Into 3 parts of ethylene glycol, 2 parts of methyl propanediol, 1 part of propane diols, 2 parts of DPG, 2 parts of butanediol, 3 parts of sorbierite, polyethylene glycol 1 part.Polyalcohol plays the net skin effect of polyoxy in the composition, improves the metabolic capability of skin, hormone mediates the factor in skin The hormone rubbish metabolism of face deposition is fallen.
Preparation method:The active matter, deionized water are mixed and inserted in kettle, 75~85 DEG C are heated to;It is polyalcohol, sweet Oil, synthesis saualane, tocopherol acetate, cetostearyl alcohol, the mixing of Butyrospermum parkii fruit fatty oil are inserted in oil cauldron, it is heated to 65~ 75℃;Gained aqueous solution and oily solution are inserted to be mixed and emulsifying 10min in emulsification pot, and gained emulsion is cooled to 36~ 38 DEG C, deoxidation sulfydryl enzyme and allantoin stir 10min;6~12h is stood after discharging, is added after preservative, filling and package is produced; Described preservative is by Metagin vinegar, Phenoxyethanol, double imidazolidinyl urea according to 1:1:2 weight ratio mixing.
Assess the validity that the resulting composition finished product of the present embodiment 1 recovers and repaired skin barrier to homeliness type acne skin damaged And security:83 homeliness type acne patients are chosen, Essence is repaired using clear acne, once in the morning and once at night, observation uses front and rear skin Damaging improves and skin physiology function change situation.Improve skin damaged situation result:Cure and effective number is 67 people, effective percentage is 81%, before and after treatment, moisture has an obvious rising, and sebum level, is lost in and is changed less through transepidermal water, and has statistics Meaning, illustrates that the skin care item heavy metal of the formula is removed with the logical effect of hair follicle row significantly, skin repair effect is not failed to understand on opposite It is aobvious.
Embodiment 2:
Formula:5 parts of deoxidation sulfydryl enzyme, 25 parts of active matter, 20 parts of polyalcohol, 20~30 parts of glycerine, synthesis 5 parts of saualane, 1 part of tocopherol acetate, 3 parts of cetostearyl alcohol, 1 part of allantoin, 15 parts of Butyrospermum parkii fruit fatty oil, plus deionized water is to 100 parts. The deoxidation sulfydryl enzyme is mixed by the major ingredient and auxiliary material of following parts by weight, Ismipur -2 ' 10 parts of-deoxyribonucleoside, wood 2 parts of melon protease, 4 parts of niacinamide, 4 parts of silandiol salicylate, 1 part of natural fatty alcohol.The deoxidation sulfydryl enzyme it is main into It is divided into Ismipur -2 '-deoxyribonucleoside, from Dalian, Mei Lun Bioisystech Co., Ltd buys, and coordinates obtained de- with auxiliary material Oxygen sulfydryl enzyme, has reduction for steroid dependent dermatitis, with very strong prosthetic, can repair skin in damaged condition, Dependence of the skin to hormone is blocked from root, skin is recovered original again with the principle of " being repaired in row " and penetrating is good for Health.The active matter is mixed by following raw material according to shown weight ratio, 3 parts of wolfberry fruit extract, eucommia ulmoides extracts 2 Part, smooth 1 part of fruit elm chloroxylon swietenia bark extract, 2 parts of Schisandra fruit extract, 2 parts of Astragalus Root P.E, the bark of official magnolia bark extract 1 Part, 2 parts of tea extract, 1 part of dipotassium glycyrrhizinate, 1 part of camomile extract, 2 parts of chlorella extract, Lupinus albus albumen hair 2 parts of ferment product, -10.25 parts of oligopeptides, -30.25 parts of oligopeptides, -50.25 parts of oligopeptides.Active matter has to release in the composition changes lead again Nourishing effect, mops up lead and mercury, and cell repair is carried out while excluding release heavy metal, furthermore with biotechnology extract it is pure Natural plant composition can lift immunity and metabolism.The polyalcohol is mixed by following raw material according to shown weight ratio Conjunction is made, 3 parts of ethylene glycol, 2 parts of methyl propanediol, 1 part of propane diols, 2 parts of DPG, 2 parts of butanediol, 3 parts of sorbierite, poly- second 1 part of glycol.Polyalcohol plays the net skin effect of polyoxy in the composition, improves the metabolic capability of skin, hormone mediates the factor flesh The hormone rubbish metabolism of deposition is fallen inside skin.
Preparation method:The active matter, deionized water are mixed and inserted in kettle, 75~85 DEG C are heated to;It is polyalcohol, sweet Oil, synthesis saualane, tocopherol acetate, cetostearyl alcohol, the mixing of Butyrospermum parkii fruit fatty oil are inserted in oil cauldron, it is heated to 65~ 75℃;Gained aqueous solution and oily solution are inserted to be mixed and emulsifying 10min in emulsification pot, and gained emulsion is cooled to 36~ 38 DEG C, deoxidation sulfydryl enzyme and allantoin stir 10min;6~12h is stood after discharging, is added after preservative, filling and package is produced; Described preservative is by Metagin vinegar, Phenoxyethanol, double imidazolidinyl urea according to 1:1:2 weight ratio mixing.
Assess the validity that the resulting composition finished product of the present embodiment 2 recovers and repaired skin barrier to homeliness type acne skin damaged And security:76 homeliness type acne patients are chosen, Essence is repaired using clear acne, once in the morning and once at night, observation uses front and rear skin Damaging improves and skin physiology function change situation.Improve skin damaged situation result:Cure and effective number is 45 people, effective percentage is 59%, before and after treatment, moisture has significant change unobvious, and sebum level, is lost in through transepidermal water and has obvious reduction, and has Statistical significance, illustrates that the skin care item of the formula have clear improvement to moisture of skin, cortex content, through transepidermal water loss, The removal of heavy metal and the logical effect of hair follicle row are poor.
Embodiment 3:
Formula:7 parts of deoxidation sulfydryl enzyme, 20 parts of active matter, 25 parts of polyalcohol, 25 parts of glycerine, 4 parts of saualane of synthesis, fertility 2 parts of phenol acetic acid esters, 2 parts of cetostearyl alcohol, 2 parts of allantoin, 13 parts of Butyrospermum parkii fruit fatty oil, plus deionized water is to 100 parts.It is described Deoxidation sulfydryl enzyme is mixed by the major ingredient and auxiliary material of following parts by weight, Ismipur -2 ' 10 parts of-deoxyribonucleoside, pawpaw egg White 2 parts of enzyme, 4 parts of niacinamide, 4 parts of silandiol salicylate, 1 part of natural fatty alcohol.The deoxidation sulfydryl enzyme main component is Ismipur -2 '-deoxyribonucleoside, from Dalian, Mei Lun Bioisystech Co., Ltd buys, and coordinates obtained deoxidation mercapto with auxiliary material Base enzyme, has reduction for steroid dependent dermatitis, with very strong prosthetic, can repair skin in damaged condition, from root Dependence of the skin to hormone is blocked on source, skin is recovered original penetrating health again with the principle of " being repaired in row ".Institute Active matter is stated to be mixed according to shown weight ratio by following raw material, it is 3 parts of wolfberry fruit extract, 2 parts of eucommia ulmoides extracts, smooth 1 part of fruit elm chloroxylon swietenia bark extract, 2 parts of Schisandra fruit extract, 2 parts of Astragalus Root P.E, 1 part of the bark of official magnolia bark extract, tealeaves 2 parts of extract, 1 part of dipotassium glycyrrhizinate, 1 part of camomile extract, 2 parts of chlorella extract, Lupinus albus protein fermentation product 2 Part, -10.25 parts of oligopeptides, -30.25 parts of oligopeptides, -50.25 parts of oligopeptides.Active matter has to release in the composition changes lead nourishing work again With, lead and mercury are mopped up, excludes and carries out cell repair while discharging heavy metal, the pure natural plant extracted furthermore with biotechnology Thing composition can lift immunity and metabolism.The polyalcohol is mixed according to shown weight ratio by following raw material and made Into 3 parts of ethylene glycol, 2 parts of methyl propanediol, 1 part of propane diols, 2 parts of DPG, 2 parts of butanediol, 3 parts of sorbierite, polyethylene glycol 1 part.Polyalcohol plays the net skin effect of polyoxy in the composition, improves the metabolic capability of skin, hormone mediates the factor in skin The hormone rubbish metabolism of face deposition is fallen.
Preparation method:The active matter, deionized water are mixed and inserted in kettle, 75~85 DEG C are heated to;It is polyalcohol, sweet Oil, synthesis saualane, tocopherol acetate, cetostearyl alcohol, the mixing of Butyrospermum parkii fruit fatty oil are inserted in oil cauldron, it is heated to 65~ 75℃;Gained aqueous solution and oily solution are inserted to be mixed and emulsifying 10min in emulsification pot, and gained emulsion is cooled to 36~ 38 DEG C, deoxidation sulfydryl enzyme and allantoin stir 10min;6~12h is stood after discharging, is added after preservative, filling and package is produced; Described preservative is by Metagin vinegar, Phenoxyethanol, double imidazolidinyl urea according to 1:1:2 weight ratio mixing.
Assess and composition finished product is made to recovering the recovery of steroid dependent dermatitis skin barrier using the present embodiment 3:Choose Steroid dependent dermatitis patient 60, according to steroid dependent dermatitis treatment guidelines, uses the antiallergies such as HCQ, imidazoles this fourth Medicine, skin damaged is that acne type uses tetracycline, tanshinone, vitamin B6, and control group uses zinc ointment, twice daily, control Treatment group uses composition finished product made from embodiment 2, twice daily, continuous to use two months.Therapeutic evaluation improves feelings with skin damaged Physiological function target improvement at condition, safety evaluatio and lesions of patients.Product Safety is evaluated:Whole therapeutic process without it is related not Good reaction.Physiologic index quantitative assessment:Epidermis water content compares before and after treatment:Treatment group and skin damaged before control group treatment are aqueous Measure and be:(18.15 ± 5.71) %, (19.33 ± 4.67) %, be respectively after treatment:(22.23 ± 4.96) %, (31.65 ± 3.24) %, than substantially increase before treatment after treatment.The comparison of grease:Fat content is before treatment group treats with control group: (80.17 ± 6.78), (77.50 ± 14.55), be respectively after treatment:(91.37 ± 8.15), (111.9 ± 10.88), treatment group Grease is significantly improved.(TEWL) is lost in through transepidermal water to compare:TEW is before treatment group treats with control group:(30.84± 7.12), (29.71 ± 5.81), TEW is respectively after treatment:(25.34 ± 3.03), (14.46 ± 5.90), treatment group's moisture stream The aobvious reduction of blindness.Conclusion:Composition finished product made from embodiment 3 is for steroid dependent dermatitis patient moisture, grease, through epidermis Water loss has clear improvement, and removes pore heavy metal and blocks effect and good to the restitution of its skin barrier, without bright Aobvious adverse reaction, security is good, is this product preferred forms.
It can be that professional and technical personnel in the field realize or used that above-mentioned embodiment, which is intended to illustrate the present invention, to above-mentioned Embodiment is modified and will be apparent for those skilled in the art, therefore the present invention includes but is not limited to Above-mentioned embodiment, it is any to meet the claims or specification description, meet with principles disclosed herein and novelty, The method of inventive features, technique, product, each fall within protection scope of the present invention.

Claims (7)

  1. It is 1. a kind of that there is the hormonal skin of face that is used for for releasing again change lead function to arrange the logical composition repaired, it is characterized in that:By with Lower raw material is made according to shown weight ratio, 5~8 parts of deoxidation sulfydryl enzyme, 15~25 parts of active matter, 20~30 parts of polyalcohol, 20~30 parts of glycerine, 3~5 parts of saualane of synthesis, 1~3 part of tocopherol acetate, 1~3 part of cetostearyl alcohol, allantoin 1~3 Part, 10~15 parts of Butyrospermum parkii fruit fatty oil, plus deionized water is to 100 parts.
  2. It is 2. according to claim 1 that there is the hormonal skin of face that is used for for releasing again change lead function to arrange the logical combination repaired Thing, it is characterized in that:The deoxidation sulfydryl enzyme is mixed by the major ingredient and auxiliary material of following parts by weight, Ismipur -2 '-deoxidation 10 parts of nucleosides, 2 parts of papain, 4 parts of niacinamide, 4 parts of silandiol salicylate, 1 part of natural fatty alcohol.
  3. It is 3. according to claim 1 that there is the hormonal skin of face that is used for for releasing again change lead function to arrange the logical combination repaired Thing, it is characterized in that:The active matter is mixed by following raw material according to shown weight ratio, 3 parts of wolfberry fruit extract, the bark of eucommia 2 parts of extract, smooth 1 part of fruit elm chloroxylon swietenia bark extract, 2 parts of Schisandra fruit extract, 2 parts of Astragalus Root P.E, Magnolia bark 1 part of extract, 2 parts of tea extract, 1 part of dipotassium glycyrrhizinate, 1 part of camomile extract, 2 parts of chlorella extract, white feather fan 2 parts of legumin tunning, 0.25 part of oligopeptides -1,0.25 part of oligopeptides -3,0.25 part of oligopeptides -5.
  4. It is 4. according to claim 1 that there is the hormonal skin of face that is used for for releasing again change lead function to arrange the logical combination repaired Thing, it is characterized in that:The polyalcohol is mixed by following raw material according to shown weight ratio, 3 parts of ethylene glycol, methyl-prop two 2 parts of alcohol, 1 part of propane diols, 2 parts of DPG, 2 parts of butanediol, 3 parts of sorbierite, 1 part of polyethylene glycol.
  5. 5. the hormonal skin of face that is used for that having according to any one of Claims 1-4 releases again change lead function arranges logical repair Multiple composition, it is characterized in that:The composition is made up of following raw material according to shown weight ratio, 7 parts of deoxidation sulfydryl enzyme, 20 parts of active matter, 25 parts of polyalcohol, 25 parts of glycerine, 4 parts of saualane of synthesis, 2 parts of tocopherol acetate, 2 parts of cetostearyl alcohol, urine 2 parts of Bursin, 13 parts of Butyrospermum parkii fruit fatty oil, plus deionized water is to 100 parts.
  6. It is 6. according to claim 1 that there is the hormonal skin of face that is used for for releasing again change lead function to arrange the logical combination repaired Thing, it is characterized in that:The preparation method of the composition comprises the following steps,
    Step (1):The active matter, deionized water are mixed and inserted in kettle, 75~85 DEG C are heated to;
    Step (2):Polyalcohol, glycerine, synthesis saualane, tocopherol acetate, cetostearyl alcohol, the mixing of Butyrospermum parkii fruit fatty oil Insert in oil cauldron, be heated to 65~75 DEG C;
    Step (3):Step (1) resulting solution and step (2) resulting solution are inserted and mixed and emulsifying in emulsification pot 10min, gained emulsion is cooled to 36~38 DEG C, deoxidation sulfydryl enzyme and allantoin, stirs 10min;
    Step (4):6~12h is stood after discharging, is added after preservative, filling and package is produced.
  7. It is 7. according to claim 6 that there is the hormonal skin of face that is used for for releasing again change lead function to arrange the logical combination repaired Thing, it is characterized in that:Preservative described in step (4) is by Metagin vinegar, Phenoxyethanol, double imidazolidinyl urea according to 1:1:2 Weight ratio is mixed.
CN201710437850.1A 2017-06-12 2017-06-12 It is a kind of that there is the hormonal skin of face that is used for for releasing again change lead function to arrange the logical composition repaired Pending CN107157798A (en)

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Citations (4)

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Publication number Priority date Publication date Assignee Title
CN101658470A (en) * 2009-09-18 2010-03-03 北京欧凯纳斯科技有限公司 Moisturizer and preparation method thereof
CN102440943A (en) * 2011-08-25 2012-05-09 唯美度科技(北京)有限公司 Composition for caring and improving aged or damaged skin
CN102764217A (en) * 2012-07-29 2012-11-07 何黎 Functional skin care product containing purslane extractive and preparation method thereof
CN106726653A (en) * 2017-03-09 2017-05-31 肇庆市凯捷科技有限公司 A kind of reparation mask composition for saving hormone face and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101658470A (en) * 2009-09-18 2010-03-03 北京欧凯纳斯科技有限公司 Moisturizer and preparation method thereof
CN102440943A (en) * 2011-08-25 2012-05-09 唯美度科技(北京)有限公司 Composition for caring and improving aged or damaged skin
CN102764217A (en) * 2012-07-29 2012-11-07 何黎 Functional skin care product containing purslane extractive and preparation method thereof
CN106726653A (en) * 2017-03-09 2017-05-31 肇庆市凯捷科技有限公司 A kind of reparation mask composition for saving hormone face and preparation method thereof

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SANEYOSHI,M ET AL: "SYNTHETIC NUCLEOSIDES AND NUCLEOTIDES .14. FACILE SYNTHESIS AND ANTI-TUMOR ACTIVITIES OF 6-MERCAPTOPURINE 2"-DEOXYRIBOSIDE AND RELATED-COMPOUNDS", 《 JOURNAL OF PHARMACOBIO-DYNAMICS》 *

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Application publication date: 20170915