KR20200074287A - Composition for Improving Skin Condition or for Quasi-Drugs, Comprising Plant Extracts - Google Patents

Abstract

The present invention relates to a composition for improving skin containing a plant extract. Specifically, the present invention relates to a cosmetic or quasi-drug composition for skin whitening, skin inflammation alleviation, skin elasticity improvement, antioxidation, skin regeneration, skin wrinkle prevention or amelioration, or skin aging prevention or alleviation, containing a Hydrangea macrophylla extract, Centella asiatica extract, paprika extract, and Dracaena draco extract.

Description

Composition for improving skin condition or quasi-drug containing plant extracts {Composition for Improving Skin Condition or for Quasi-Drugs, Comprising Plant Extracts}

The present invention relates to a composition comprising a plant extract, specifically, a hydrangea extract, a hyacinth extract, a paprika extract, and a hemolytic extract, for improving skin condition or for quasi-drugs.

The skin serves to protect the body from external stimuli and to maintain the homeostasis of the human body by suppressing evaporation of moisture from inside the skin. Since such skin is exposed to the outside, inflammation or pigmentation may occur due to external factors or irritation.

When inflammation or pigmentation is exposed to externally visible skin, not only physical pain due to disease, but also psychological atrophy due to external reasons is a problem. In recent years, excessive clothing friction due to clothing that tightens the body, such as skinny jeans, long sitting conditions, excessive sweating, and excessive vaginal discharge due to stress, such as underarms, thighs, groin area, genitals and surroundings While inflammation, pigmentation, and itchiness on the skin have increased, there have been many cases where skin exposure in the body parts, which were not well-known in appearance, is desired because of exposure to clothes, such as short shorts and sleeveless tops. Accordingly, the demand for functional cosmetics or functional quasi-drugs is increasing. Furthermore, in the case of women or men who have economic power, they perform surgical therapy and laser whitening for the treatment of acne, blemishes, blemishes, pigmentation due to skin inflammation, or directly purchase products from the United States and Japan in the range of 60,000 to 200,000 won overseas. It is imported and used in this way, and some of them are using ampoule (used twice a week) for about 150,000 won per session as a method of culturing their own stem cells. On the other hand, when such skin pigmentation is accompanied by skin inflammation, the cosmetic effect, for example, improvement of skin whitening and skin elasticity, as well as the effect of improving skin inflammation are expected simultaneously.

However, existing functional cosmetics or functional quasi-drugs have the inconvenience of preparing each product individually according to functions such as skin moisturization, inflammation improvement, whitening, and skin elasticity improvement. When preparing multiple products as described above, the cost is high, there is inconvenience in storage and use, and the product to be applied later may not be properly absorbed due to the application of multiple products to the skin. The above-mentioned Japanese products also have a whitening effect based on chemical raw materials, and some products, such as the American "Amaira Natural Lightening" based on oriental traditional medicine, focused only on odor removal and whitening, and have no therapeutic effect on inflammatory diseases or redness of the skin It may also show side effects such as

The object of the present invention is to improve the skin condition, specifically skin whitening, skin inflammation improvement, skin elasticity improvement, antioxidant, skin regeneration, skin wrinkle prevention or improvement, and / or skin aging prevention or improvement effect is excellent, there is no side effect It is to provide a cosmetic or quasi-drug composition.

According to an aspect of the present invention, skin whitening, skin inflammation improvement, skin elasticity improvement, antioxidant, skin regeneration, skin wrinkle prevention or improvement, or skin aging, comprising hydrangea extract, centella extract, paprika extract, and hemolytic extract A cosmetic composition for preventing or improving is provided.

According to another aspect of the present invention, skin whitening, skin inflammation improvement, skin elasticity improvement, antioxidant, skin regeneration, skin wrinkle prevention or improvement, or skin aging, comprising hydrangea extract, centella extract, paprika extract, and hemolytic extract Provided is a quasi-drug composition for prevention or improvement.

According to another aspect of the invention, the cosmetic or quasi-drug composition is based on the total weight of the composition, the hydrangea extract is 1 to 4% by weight, the centella extract is 0.1 to 5% by weight, the paprika extract is 0.1 to 3% by weight %, the hemolytic water extract may be included in an amount of 0.1 to 3% by weight.

According to another aspect of the present invention, the cosmetic or quasi-drug composition may further include an additional skin lightening agent.

According to another aspect of the invention, the additional skin lightening agent may be niacinamide, licorice extract, or a combination thereof.

According to another aspect of the present invention, the cosmetic or quasi-drug composition may further include one or more selected from the group consisting of skin penetration enhancers and fragrances.

According to another aspect of the present invention, the skin penetration enhancer is squalane, and the fragrance may be a vegetable oil obtained from flowers, buds, fruits, leaves, branches, stems, roots, and natural resins of aromatic plants.

According to an embodiment of the present invention, the composition of the present invention, based on the total weight of the composition, 1 to 4% by weight of hydrangea extract (specifically 3.5% by weight), 0.1 to 5% by weight of centella extract (specifically 3% by weight) %), paprika extract 0.1-3% by weight (specifically 2% by weight), hemolytic extract 0.1-3% by weight (specifically 2% by weight), vegetable squalane 1.5-4% by weight (specifically 2% by weight), niacin Amide 0.1 to 3% by weight (specifically 2% by weight), licorice extract 0.1 to 5% by weight (specifically 3% by weight), and vegetable oil fragrance 0.01 to 5% by weight (specifically 1% by weight) may be included. .

According to another aspect of the present invention, a mask pack including the cosmetic composition in a sheet for a mask pack is provided.

According to another aspect of the present invention, a quasi-drug is provided by immersing or impregnating the quasi-drug composition on a sheet or coating the skin contact area of the sheet.

By using the composition according to the invention, not only the pigmentation of the skin is improved or eliminated, but also the skin inflammation is improved. Accordingly, the composition according to the present invention exerts an effect on skin whitening, skin inflammation improvement, skin elasticity improvement, antioxidant, skin regeneration, skin wrinkle prevention or improvement, or skin aging prevention or improvement. In addition, itching of the skin can be alleviated or relieved.

1 is a view schematically showing the design of a sanitary napkin or a disposable liner according to an embodiment of the present invention.

Hereinafter, embodiments of the present invention will be described in more detail, but they are for illustrative purposes and should not be interpreted as a method of limiting the scope of the present invention.

The term "extract" used in the present invention includes an extract obtained by the extraction treatment of the plant and all formulations that can be formed using the extract. Specifically, the extract may be the extract itself or a diluent or concentrate of the extract, a dried product obtained by drying the extract, a crude product or a purified product of the extract, or a mixture thereof.

The extract of the present invention can be extracted from natural, hybrid or variant plants of the respective plants, and can also be extracted from plant tissue cultures.

In the extract of the present invention, its extraction method can be extracted according to a method commonly used in the art. As the extraction solvent used in the extraction method, water or various organic solvents may be used. Specifically, water, alcohol, acetone, butylene glycol, ethyl acetate, diethyl acetate, diethyl ether, benzene, chloroform and hexane are used. It may be any one or more selected from the group consisting of, when using alcohol as a solvent, preferably a lower alcohol having 1 to 4 carbon atoms. Examples of the extraction method include vacuum low temperature extraction, room temperature extraction, hot water extraction, cold extraction, reflux cooling extraction, ultrasonic extraction and steam extraction, and the like, but are not limited thereto. The extraction method may be carried out alone or in combination of two or more methods.

Vacuum low temperature extraction is a method of extracting under a low temperature condition using an extraction solvent under vacuum. In the case of extracting by the vacuum low temperature extraction method in the present invention, it is preferable to repeatedly extract 1 to 5 times, and it is more preferable to repeatedly extract 3 times, but is not limited thereto. The extraction solvent may be added 0.1 to 10 times the weight of the dried plant, it is preferable to add 0.3 to 5 times. The extraction temperature may be preferably 30°C to 70°C, more preferably 40°C to 60°C, most preferably 60°C, and the extraction time is preferably 12 hours to 48 hours, but is not limited thereto. . When extracting by the vacuum low temperature extraction method, there is an advantage that can improve the extraction efficiency without destroying or loss of the active ingredient, furthermore, when preparing a mixed extract by the vacuum low temperature extraction method, the skin condition is improved by the collaboration between the active ingredients , There is an advantage that the skin disease treatment efficacy becomes more excellent.

In the method for producing the extract of the plant of the present invention, the vacuum concentration is preferably a vacuum vacuum concentrator or a vacuum rotary evaporator, but is not limited thereto. In addition, drying is preferably carried out under reduced pressure drying, vacuum drying, boiling drying, spray drying or freeze drying, but is not limited thereto.

The composition according to the present invention has biological activity and exerts an excellent effect on improving skin condition.

More specifically, the composition according to the present invention includes hydrangea extract, centella extract, paprika extract, and hemolytic extract and improves skin condition, specifically skin whitening, skin inflammation improvement, skin elasticity improvement, antioxidant, skin regeneration, skin wrinkles It has an effect of preventing or improving, and/or preventing or improving skin aging.

As used in the present invention, the term "skin condition improvement" specifically refers to skin whitening, skin inflammation improvement, skin elasticity improvement, antioxidant, skin regeneration, skin wrinkle prevention or improvement, and/or skin aging prevention or improvement.

As used in the present invention, the term "skin whitening" refers to all actions to inhibit or prevent skin deposition of melanin by inhibiting the synthesis of melanin.

The term used in the present invention, "improve skin inflammation" refers to all actions that suppress the production of NO by reducing the immune response.

As used in the present invention, the term "improve skin elasticity" refers to an increase in elasticity to the skin, and refers to suppressing or inhibiting loss of skin elasticity or alleviating reduced elasticity.

As used in the present invention, the term "antioxidation" means that the free radicals attack the cells to prevent the phenomenon of promoting aging.

As used in the present invention, the term "skin regeneration" refers to the recovery of skin tissue against damage caused by external and internal causes of the skin. The damage caused by the external cause may include ultraviolet rays, external contaminants, wounds, trauma, etc., and the damage caused by the internal cause may include stress.

As used in the present invention, the term "prevent or improve skin wrinkles" refers to inhibiting or inhibiting the formation of wrinkles on the skin, or alleviating wrinkles already generated.

As used in the present invention, the term "skin aging" refers to all diseases caused by an increase in free radicals, and non-limiting examples of skin aging include wrinkles, sagging of the skin, reduction in elasticity, and the like.

As used herein, the term "skin pigmentation" refers to any action or condition in which the color of the skin darkens due to increased synthesis of melanin. Examples of the skin pigmentation include spots, freckles, spots, sun pigment, pigmentation after drug use, pigmentation after inflammation, and gestational pigmentation.

As used herein, the term “skin inflammation” refers to any skin inflammation caused by immune stimulation. Non-limiting examples of the skin inflammation include contact dermatitis, atopic dermatitis, eczema, hanpojin, athlete's foot, fungal spots, seborrheic dermatitis, dark circles, psoriasis, and the like.

As used in the present invention, the term "skin moisturizing" refers to all actions that maintain the smoothness of the skin by supplying moisture to the skin or blocking evaporation of moisture to maintain the flexibility of the skin and induce uniform exfoliation.

As used herein, the term "improvement" means any action that at least reduces the severity of a condition or a parameter associated with treatment, eg, the severity of symptoms.

According to an embodiment of the present invention, skin whitening, skin inflammation improvement, skin elasticity improvement, antioxidant, skin regeneration, skin wrinkle prevention or improvement, and/or skin aging prevention or improvement, including hydrangea extract, vesicle extract, and paprika extract Provide a cosmetic composition for.

The cosmetic composition of the present invention is a solution, ointment for external use, facial cream, nourishing lotion, soft lotion, pack, softener, latex, makeup base, essence, soap, shampoo, conditioner, body oil, body cream, body lotion, bath, sunscreen From the group consisting of cream, sun oil, suspension, emulsion, paste, gel, lotion, powder, soap, cleansing oil, cleansing cream, cleansing foam, cleansing water, powder foundation, emulsion emulsion, wax foundation, patch, and spray It can be prepared in a selected formulation, but is not limited thereto.

According to the present invention, the cosmetic composition may be contained in a sheet for a mask pack and provided as a mask pack. Specifically, the cosmetic composition of the present invention may be applied to the skin by immersing, impregnating, or coating the mask pack sheet. The sheet may be a non-woven sheet made of a material such as pulp, synthetic fiber (Viscos Rayon), chemical fiber (PET, PP, Nylon, etc.) and a natural material sheet such as hydrogel, biocellulose, and cotton.

The cosmetic composition of the present invention may further include supplements such as additional skin whitening agents, skin penetration enhancers, antioxidants, and fragrances, in addition to the hydrangea extract, centella extract, paprika extract, and hemolytic extract of the present invention. have. In addition, the cosmetic composition of the present invention may further include a cosmetically acceptable carrier that is formulated in a general skin cosmetic. The cosmetically acceptable carrier included in the cosmetic composition of the present invention varies depending on the formulation of the cosmetic composition.

When the formulation of the present invention is an ointment, cream, pack, paste, or gel for external use, it is a fat or oil (animal fat or vegetable fat), wax ester, paraffin, starch, trakant, cellulose derivative, polyethylene glycol, silicone, as a carrier component. Bentonite, silica, talc, zinc oxide, hydrocarbons, moisturizers, thickeners, alcohol, purified water, etc. may be used, but is not limited thereto. These may be used alone or in combination of two or more. As the oil, macadamia nut oil, avocado oil, olive oil, castor oil, sweet almond oil or the like may be used alone or in combination of two or more, and as a wax ester, jojoba oil, beeswax, carnauba wax, candelina Wax, lanolin, or the like may be used alone or in combination of two or more, and as silicone, dimethylpolysiloxane, methylphenylsiloxane, cyclomethicone, polymer silicone, etc. may be used alone or in combination of two or more, and hydrocarbons include liquid paraffin, petrolatum, Two or more types of solid paraffin, microcrystalline wax, and ceresin can be used alone, and examples of the moisturizer include glycerin, propylene glycol, butylene glycol, polyethylene glycol, sorbitol, sodium lactate, pyrrolidone carboxylic acid, and dipropylene glycol. , Maltitol, hyaluronic acid, natto gum, etc. can be used alone or in combination of two or more, and as the thickener, guar gum, locust bean gum, pectin, xanthan gum, carboxyvinyl polymer, cellulose derivatives, etc. can be used alone or in combination of two or more. As the alcohol, ethyl alcohol or the like may be used alone or in combination of two or more.

When the formulation of the present invention is a powder or a spray, lactose, talc, silica, aluminum hydroxide, calcium silicate, polyamide powder, or the like may be used as a carrier component, and in the case of a spray, additionally, chloro fluorohard Propellants such as locarbon, propane/butane or dimethyl ether, but are not limited thereto. These may be used alone or in combination of two or more.

When the formulation of the present invention is a solution or emulsion, a solvent, solubilizer or emulsifier may be used as a carrier component, such as water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene Glycol, 1,3-butyl glycol oil, and the like can be used, in particular, cottonseed oil, peanut oil, corn seed oil, olive oil, castor oil and sesame oil, glycerol aliphatic esters, polyethylene glycol or fatty acid esters of sorbitan It can be used, but is not limited thereto. These may be used alone or in combination of two or more.

When the formulation of the present invention is a suspension, liquid diluents such as water, ethanol or propylene glycol as carrier components, suspensions such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester, micro Crystalline cellulose, aluminum metahydroxide, bentonite, agar or trakant may be used, but is not limited thereto. These may be used alone or in combination of two or more.

When the formulation of the present invention is a soap, alkali metal salt of fatty acid, fatty acid hemiester salt, fatty acid protein hydrolyzate, isethionate, lanolin derivative, aliphatic alcohol, vegetable fat, glycerol, sugar, etc. It can be used, but is not limited thereto. These may be used alone or in combination of two or more.

When the cosmetic composition of the present invention is contained in a sheet for a mask pack and provided as a mask pack, in addition to the cosmetic composition of the present invention, the mask pack may further include an auxiliary component such as a moisturizer, a thickener, and a porous powder. As the moisturizing agent, glycerin, propylene glycol, butylene glycol, polyethylene glycol, sorbitol, sodium lactate, pyrrolidone carboxylic acid, dipropylene glycol, maltitol, hyaluronic acid, natto gum, etc. can be used alone or in combination of two or more. As a thickener, guar gum, locust bean gum, pectin, xanthan gum, carboxyvinyl polymer, cellulose derivatives, etc. can be used alone or in combination of two or more, and as the porous powder, zinc oxide, titanium dioxide, etc. can be used alone or in combination of two or more. Can.

In addition, the present invention is a skin whitening, skin inflammation improvement, skin elasticity improvement, antioxidant, skin regeneration, skin wrinkle prevention or improvement, and/or skin aging prevention, including hydrangea extract, centella extract, paprika extract, and hemolytic extract, or Provided is a quasi-drug composition for improvement.

In the present invention, the term "quasi-drug" is a fiber, rubber product or the like used for the purpose of treating, alleviating, treating or preventing a disease of a person or animal, has a weak effect on the human body or does not directly act on the human body, Or it means a product that is not a machine or similar, and one of agents used for sterilization, pesticide and similar purposes to prevent infectious diseases. However, even if it falls within the definition of quasi-drugs, the articles used for the purpose of diagnosing, treating, alleviating, treating or preventing diseases of humans or animals are not apparatuses, machines or devices, and pharmacological in the structure and function of humans or animals. Items used for the purpose of influencing are excluded from non-equipment, machinery or equipment.

In the present invention, the quasi-drug is in the group consisting of sanitary napkin, disposable liner, mask, eye patch, bandage, elastic bandage, gypsum bandage, cylindrical elastic bandage, gauze, cotton wool, bandage, anti-odor agent, sweat bandage, softening agent, ointment agent, and cataplasma It may be one or more selected, but is not limited thereto.

When the quasi-drug composition of the present invention is used as a quasi-drug additive, the composition can be added as it is or used with other quasi-drugs or quasi-drug components, and can be suitably used according to a conventional method. The mixing amount of the active ingredient can be appropriately determined according to the purpose of use. Specifically, the quasi-drug composition of the present invention may be provided as a quasi-drug, specifically, a sanitary napkin or a disposable liner by immersing or impregnating the sheet with a sheet or coating the skin contact area of the sheet. The sheet may be a non-woven sheet made of a material such as pulp, synthetic fiber (Viscos Rayon), chemical fiber (PET, PP, Nylon, etc.) and a natural material sheet such as hydrogel, biocellulose, and cotton. The sanitary napkin or disposable liner may be colored using a pigment on a substrate such as a sheet. Figure 1 attached to this specification shows a design that can be used in the sanitary napkin or disposable liner.

Hereinafter, the components included in the composition of the present invention will be described in more detail.

Hydrangea extract

Hydrangea is a deciduous shrub of the dicotyledonous plant Rosales Hydrangeaceae Hydrangea, and is known as Hydrangea macrophylla. Hydrangeas are distributed in Korea, China, and Japan. In Korea, they are mainly grown in the southern regions of Jeju Island, Geoje Island, and the South Coast. In the private sector, the flowers of hydrangea were dried to be used as an antipyretic agent. Hydrangea was found to contain Phyllodulcin and Hydrangenol. In particular, the leaves of hydrangea contain Hydrangeaic acid, etc., and the roots of Hydrangea contain halouginone, which is known as a component that suppresses the progression of various autoimmune diseases. It is said to be of high value.

In the present invention, the hydrangea extract may be extracted from various organs of natural, hybrid, and varietal plants, and may be extracted by various extraction methods described above. In the present invention, the hydrangea extract is preferably extracted from one or more selected from the roots and ground parts of hydrangeas, specifically, the roots, stems, leaves, flowers of the hydrangea, the body of the fruit, the peel of the fruit, and plant tissue It may be extracted from one or more selected from the culture.

In the present invention, the hydrangea extract may be included in an amount of 1 to 4% by weight, specifically 2 to 3.5% by weight, based on the total weight of the composition. In the embodiment of the present invention was used at 3.5% by weight. By including the hydrangea extract in an amount within the above range, it is possible to effectively exert an effect of improving skin condition or skin disease. When the hydrangea extract is excessively small compared to the total weight of the composition, the effect of improving the skin condition or skin disease is negligible, and when it is excessively large, the medicinal properties are stronger than the obvious effect of increasing the content, making the user feel the weight (burden) and more The above effects do not appear.

Centella extract

Centella asiatica of the present invention belongs to the mountain family, and is a perennial plant mainly found in South Asia. In Korea, it lives in low-lying wetlands in Jeju Island and in the central and southern regions. As an ingredient in the extract of Cypress, asiatic acid, asiaticoside, madecassic acid, and madecassoside have been reported. In addition, Centella sol extract has been used as a soothing ingredient in soothing and weakening skin weakened by irritation from Madekasol (a drug of Dongkuk Pharmaceutical). According to the present invention, it is understood that this component serves to inhibit melanin formation and has a high contribution to the whitening function, and also serves to suppress or eliminate the causative agent of skin diseases.

In the present invention, the centella extract can be extracted from various organs of natural, hybrid, and varietal plants, and can be extracted by various extraction methods described above. The centella extract may be extracted from one or more selected from the root and the upper part of the centella, and may be specifically extracted from the upper part.

In the present invention, the centella extract may be included in an amount of 0.1 to 5% by weight, specifically 2 to 3% by weight, based on the total weight of the composition. In the embodiment of the present invention was used in an amount of 3% by weight. By including the extract in the amount within the above range, it is possible to effectively exert an effect of improving skin condition or skin disease. When the extract of Cypress is excessively small compared to the total weight of the composition, the effect of improving the skin condition or skin disease is negligible, and when it is excessively large, there is no increase in the apparent effect of increasing the content.

Paprika extract

Paprika (Capsicum annuum L., Bell pepper, Paprika) is an improved crop of bell pepper, and its origin is Central America. In addition, paprika is an edible plant with a sweet taste, which is often commercially available, and thus has no side effects due to the use of the extract. As a component of paprika extract, carotene, vitamin C, vitamin B6, and p-coumaric acid have been reported. According to the present invention, paprika contains vitamin C, carotene, lycopene, and the like, and is understood to have an effect of preventing and treating pigmentation due to antioxidant activity and inhibition of melanin pigment, and also has a whitening and antibacterial action. .

In the present invention, the paprika extract may be extracted from various organs of natural, hybrid, and varietal plants, and may be extracted by various extraction methods described above.

The paprika extract may be included in an amount of 0.1 to 3% by weight, specifically 1.5 to 2.5% by weight based on the total weight of the composition. In the embodiment of the present invention was used in an amount of 2% by weight. Paprika extract by being included in an amount within the above range can effectively exhibit the effect of improving the skin condition or skin disease. When the paprika extract is excessively small compared to the total weight of the composition, the effect of improving the skin condition or skin disease is negligible, and when it is excessively large, the apparent effect of the increase in content does not appear, but rather the user with excessive weight (weakness) They can put a burden on the product.

Hemolytic water extract

Hemolytic water (Dracaena draco) is an evergreen shrub of the Liliaceae family and is native to the African Canary Islands. It is called dragon's blood because the sap from the stem is red, and this hemolysis is known to have a therapeutic effect for pain or hemostasis, so it is processed and consumed as a medicine or used as a colorant, anticorrosive, or preservative. Was also used as a cosmetic ingredient.

Hemolytic water extract may be extracted from leaves, stems, and the like. The method of extracting the hemolytic water extract is not particularly limited, and may be extracted by a conventional extraction method.

The hemolytic water extract may be included in an amount of 0.1 to 3% by weight, specifically 1.5 to 2.5% by weight based on the total weight of the composition. In the embodiment of the present invention was used in an amount of 2% by weight. By containing the hemolytic water extract in an amount within the above range, it is possible to effectively exert an effect of improving skin condition or skin disease. When the paprika extract is excessively small compared to the total weight of the composition, the improvement effect is negligible, and when it is excessively increased, there is no obvious increase in effect due to the increase in content, but rather, the excessive weight (medicinal feeling) allows users to It can be a burden.

Hydrangea extract: Centella extract: Paprika extract: Hemolytic water extract may have a weight ratio of 0.5 to 2: 0.5 to 2: 0.5 to 2: 0.5 to 2, specifically 1 to 2: 1 to 2: 0.5 to 1.5: 0.5 To 1.5. According to one embodiment according to the composition of the present invention may be combined in a ratio of 1 to 1.6: 1: 0.6 to 1: 0.6 to 1.

Other additional ingredients

Additional skin whitening agents

The composition of the present invention may further include an additional skin lightening agent.

These additional skin whitening agents include phenylethylresorcinol, 4-hexyl resorcinol, a-arbutin, kojic acid, nivitol, ascorbyl-2-glucoside, niacinamide, natural extracts ( For example, licorice extract, mulberry extract, etc.) and combinations thereof, but are not limited thereto. According to one embodiment of the composition of the present invention, niacinamide, licorice extract, or a combination thereof may be used as an additional skin lightening agent.

The niacinamide is a bioactive amide of vitamin B3, also known as nicotinamide or pyridine-3-carboxylic acid. The niacinamide not only has a whitening effect, but also protects the skin and prevents oxidation of its constituents, thereby helping maintain skin health, nourishing the skin, and increasing energy levels to help metabolism, and the level of ceramide and fatty acids in the skin It has the effect of increasing. The niacinamide may be purchased commercially or directly synthesized, but is not limited thereto.

Licorice, also called Glycyrrhiza uralensis or Licorice, is a medicinal plant that grows in northeastern China and all over Asia. The licorice extract can be obtained using various organs, tissues (eg, roots, leaves, flowers, stems, fruits, seeds, etc.) of licorice, and most preferably, is an extract obtained from the roots of licorice. Licorice contains a lot of glycyrrhizin, flavonoids, saponins, coumarins, tannins, and enzymes, which can remove harmful oxygen produced by ultraviolet rays and prevent the photooxidation of melanin. In addition, the licorice extract can act as a natural preservative for product stability and can also help moisturize and condition the skin. Licorice extract can be obtained using methods known in the art.

When the composition of the present invention includes the additional skin lightening agent, it may be included in an amount of 0.1 to 10% by weight, specifically 0.2 to 8% by weight, based on the total weight of the composition containing the skin whitening agent. More specifically, the composition of the present invention may include niacinamide in an amount of 0.1 to 3% by weight and licorice extract in an amount of 0.1 to 5% by weight as an additional skin whitening agent. In an embodiment of the present invention, niacinamide was used in an amount of 2% by weight and licorice extract in an amount of 3% by weight. When the additional skin whitening agent is included within the above range, there is an advantage that the whitening effect is enhanced.

Skin penetration enhancer

The composition of the present invention may further include a skin penetration enhancer. A skin penetration enhancer is a component that allows a desired component to penetrate into the blood vessel cells of the skin with a high absorption rate. Such skin penetration enhancers include, but are not limited to, isopropyl alcohol, isobutyl alcohol, isopropyl myristate, propylene glycol, squalane, and combinations thereof.

The squalane is a high-grade oily raw material excellent in moisturizing effect with rich usability and safety compared to squalene, which is an unsaturated hydrocarbon, and has an excellent transdermal absorption rate due to its high affinity with skin lipids as a skin sebum component.

According to an embodiment of the composition of the present invention, preferably, squalane, specifically vegetable squalane, may be used as the skin penetration enhancer. According to the present invention, it is understood that the vegetable squalane also has a bactericidal action.

When the composition of the present invention includes the skin penetration enhancer, it may be included in an amount of 1.5 to 4% by weight, specifically 1.5 to 2.5% by weight, based on the total weight of the composition containing the skin penetration enhancer. In one embodiment of the present invention, vegetable squalane was used in an amount of 2% by weight. When the skin penetration enhancer is included within the above range, the transdermal absorption rate of the active ingredient increases. If included above 4% by weight, there may be a possibility of causing sebum on the skin.

Antioxidant

The composition of the present invention may further include an antioxidant that can prevent or reduce oxidative damage to the skin.

Such antioxidants include water-soluble antioxidants, such as sulfhydryl compounds and derivatives thereof (eg, sodium metabisulfite and N-acetyl-cysteine), lipoic acid and dihydrolipoic acid, resveratrol, lactoferrin, and ascorbic acid. And ascorbic acid derivatives (eg, ascorbyl palmitate and ascorbyl polypeptide). Oil-soluble antioxidants suitable for use in the compositions of the present invention are butylated hydroxytoluene, retinoids (e.g. retinol and retinyl palmitate), different types of tocopherols (e.g. alpha-, gamma-, and delta- Tocopherols and esters thereof, for example acetate) and mixtures thereof, tocotrienols and ubiquinones. Natural extracts containing antioxidants suitable for use in the compositions of the present invention include flavinoids, isoflavinoids, and derivatives thereof, such as extracts containing genistein and diazein, extracts containing resveratrol, etc. It is not limited to this. As an antioxidant in the composition of the present invention, natural extracts, specifically soybean extracts, clover extracts, or mixtures thereof may be used.

When included in the composition of the present invention, the antioxidant may be included in 0.5 to 10% by weight, specifically 1 to 5% by weight relative to the total weight of the composition. According to one embodiment, it may be included in 3% by weight. When the antioxidant is included in the above range, there is an advantage that can prevent or remove the oxidative damage of the skin.

air freshener

The composition of the present invention may further include a fragrance.

As the fragrance, any fragrance may be used as long as it has a fragrance or has a deodorizing or deodorizing effect. The fragrance is a natural fragrance, but is not limited thereto. Examples of the natural fragrance include animal flavors and vegetable oils.

The animal fragrances include musk, civet, ambergris (amber scent) and castor. Since these animal fragrances are extracted by using the components of the fragrance with alcohol, the production amount is low and the price is very expensive. Usually, a very small amount is used as a material for fragrances combined with perfumes.

The vegetable oil is obtained from flowers, buds, fruits, leaves, branches, stems, roots and natural resins of aromatic plants. The vegetable oil may be an aqueous solution obtained by steam distillation of flowers or leaves, but most of them are volatile oily substances that are lighter than water and are distinguished from fats and oils as essential oils. As a component of the vegetable oil, many terpene compounds such as mono and sesquiterpene hydrocarbons obtained by polymerization of 2 to 3 molecules of isoprene and derivatives thereof such as alcohol, aldehyde, ketone, and ester are known. Specific examples of vegetable oils usable in the present invention include grapefruit (Citrus paradisi), lavender (Lavandula angustifolia), lemon (Citrus limonum), lemongrass (Cymbopogon citratus), rose (Rosa damascena, R. centifolia, R. gallica) ), rosemary (Rosemarinus officinalis), mandarin (Citrus reticulata), myrrh (Commiphora myrrha), basil (Ocimum basilicum), bergamot (Citrus bergamia), sandalwood (Santalum album), spearmint (Metha spicata), cinnamon (Cinnamomum zeylaum) , Cedarwood (Cedrus atlantica), Eucalyptus globulus, Jasminum grandiflorum, Geranium (Pelargonium graveolens), Juniperus communis, Thymus vulgaris, Tea tree (Melaleuca alternifoliamis) ), and thyroid lobes (Thuja occidentalis L.). Vegetable oils emit a unique natural scent according to each ingredient to provide nerve stabilization, skin soothing effects, etc., and provide superior effects in antiseptic, antiseptic, antibacterial and antiviral effects than artificial synthetic ingredients.

When the composition of the present invention includes the fragrance, it may be included in an amount of 0.01 to 5% by weight, specifically 0.1 to 3% by weight, and more specifically 0.5 to 1% by weight relative to the total weight of the composition containing the fragrance. have. In one embodiment of the present invention, vegetable oil fragrance was used in an amount of 1% by weight. When the fragrance is included within the above range, there is an advantage of imparting fragrance to the composition or deodorizing or deodorizing, and in addition, it is also possible to impart neurological stability and skin soothing effect.

Hereinafter, the present invention will be described in more detail through examples and experimental examples. These examples and experimental examples are only for explaining the present invention in detail, and the scope of the present invention is not limited to those illustrated in these examples.

Example

Organic Hydrangea Extract (product of American Herb Pharm, 45-50% alcohol) 3.5% by weight, Organic Centella Extract (product of American Herb Pharm, 45-50% alcohol) 3% by weight, Organic Paprika Extract (American Herb Pharm) Product, contains 45-50% alcohol) 2% by weight, organic hemolytic extract (USA Herb Pharm, 20% alcohol) 2% by weight, organic licorice extract (USA Herb Pharm, 20% alcohol), niacin 2% by weight of amide, 2% by weight of vegetable squalane, and 1% by weight of organic lavender (bulgaric acid) such as 55% by weight of purified water, 16% by weight of glycerin, and 15% by weight of sorbitol based on the total weight of the pack base Mixture) (81% by weight) to obtain the composition of the present invention in a cream formulation.

Experimental Example

The cream formulation prepared in the above example was tested on 100 women and 20 men with skin inflammation or skin pigmentation.

About 100 women in this experiment were women between the ages of 20 and 50, and they were applied for 4 weeks in the morning and evening by thinly applying to the skin area including the inside of the groin or around the genital area called the bikini line. (28 days) Instructed to proceed. About 20 men were men in their 20s and 50s, and they were conducted for 4 weeks by applying thinly over 2 mornings and evenings to areas with skin diseases such as groin eczema and black spots on those areas. Instructed to do so.

In women, 70% or more (except for non-response), coloring by external factors is effective from the 14th day onwards, and it is also excellent in inflammation and itching caused by vaginal discharge (after 4 days) and coloration due to wounds It showed a whitening effect. In the case of some 40~50-year-old women who experienced the whitening effect on the test subject site, they applied it to dark circles and spots around the eyes by their own will and notified and confirmed that it had the effect. As a result of proceeding with male groin staining, itching and improvement of itching following contact dermatitis, eczema eczema, hanpojin, and eczema eczema were found. These results are judged as the result that the effective properties of each raw material are properly formulated and fulfilled its role.

Hereinafter, a specific experimental case will be described.

Experimental Example 1

In the case of a 35-year-old large business woman, she noticed that the effect was excellent as a result of applying whitening effect (spots on the epilated area, rash) after brazilian waxing (epilation) after experiencing the whitening effect.

Experimental Example 2

Self-employed women, housewives, and office workers of women in their 40s and 50s have experienced a whitening effect on the affected area, and have voluntarily applied it to the spots and dark circles in the same way as above to notify them of the effective efficacy. Is used for autoimmune disease (skin disease) of a 3 year old male son's junior high school, confirming that it has had a great effect on relieving itching and redness.

Experimental Example 3

In the case of a female born in 1990, itching accompanied by inflammation was developed as an extremely stressful secretion, and as a result of using this cream, a whitening effect was developed, and after 3 days of application, it had a relatively rapid effect on inflammation and itching.

Experimental Example 4

As can be seen from the photo above, as a result of using the composition of the present invention, it can be confirmed that eczema enters the completion stage of treatment and the colored areas are gradually whitened.

Experimental Example 5

In the late 30s of this Experimental Example 5, male (male) genetically developed skin diseases such as boils at all times, and while using various ointments in hospitals and pharmacies, they were colored black as shown in the picture and even discovered in the groin eczema. As can be seen from the photo above, as a result of using the composition of the present invention for 3 weeks, it can be confirmed that the whitening effect is found on the colored part of the site of use and even the wound is cleaned up.

Experimental Example 6

The cream formulation of the present invention was used for male workers in their late 30s. Before using the cream formulation of the present invention, the man had bacterial skin irritation accompanied by blisters, which resulted in stiffening of the skin of the entire finger joint, bleeding and swelling, accompanied by blisters and itching. It is also a case in which a father passed the symptoms to a boy of 4 months. As a result of using this cream for 1 week, symptoms disappeared in 3 days for 4 months boys, and bleeding and itching disappeared from hardened keratin in men in their 30s. In progress.

Experimental Example 7

As shown in the photo above, the 45-year-old man of Experimental Example 7 was undergoing dermatology hospital treatment with eczema and spots on his armpits in the summer and autumn, and after stopping the prescription medicine in the hospital and applying only this cream, the effect improved within 10 days. This is an example.

Experimental Example 8

This Experimental Example 8 was a 25-year-old male freelance worker who experimented with the cream formulation of the present invention, and the male applied this functional cream from September 6, 2018 to the curable spots on the back of his right hand 10 years ago. , As shown in the photo above, the skin of the hardened spots on the back of the hand is softened and gradually whitened.

Claims (10)

A cosmetic composition for skin whitening, skin inflammation improvement, skin elasticity improvement, antioxidant, skin regeneration, skin wrinkle prevention or improvement, or skin aging prevention or improvement, comprising hydrangea extract, centella extract, paprika extract, and hemolytic extract. According to claim 1, With respect to the total weight of the composition, the hydrangea extract is 1 to 4% by weight, the centella extract is 0.1 to 5% by weight, the paprika extract is 0.1 to 3% by weight, the hemolytic extract is 0.1 Cosmetic composition comprising an amount of 3 to 3% by weight. The cosmetic composition according to claim 1, further comprising an additional skin lightening agent. The cosmetic composition according to claim 3, wherein the additional skin lightening agent is niacinamide, licorice extract, or a combination thereof. The cosmetic composition according to claim 1, further comprising at least one selected from the group consisting of skin penetration enhancers and fragrances. The cosmetic composition according to claim 5, wherein the skin penetration enhancer is squalane, and the fragrance is a vegetable oil obtained from flowers, buds, fruits, leaves, branches, stems, roots, and natural resins of aromatic plants. A mask pack comprising the cosmetic composition according to claim 1 in a sheet for a mask pack. Hydrangea extract, centella extract, paprika extract, and hemolytic extract, skin whitening, skin inflammation improvement, skin elasticity improvement, antioxidant, skin regeneration, skin wrinkle prevention or improvement, or skin anti-aging or improvement quasi-drug composition. The quasi-drug composition of claim 8, further comprising an additional skin lightening agent. A quasi-drug product obtained by immersing or impregnating the quasi-drug composition according to claim 1 on a sheet or coating the skin contact area of the sheet.

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