CN111773139A - Skin care product for promoting RNA transcription and preparation process thereof - Google Patents

Skin care product for promoting RNA transcription and preparation process thereof Download PDF

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CN111773139A
CN111773139A CN202010541304.4A CN202010541304A CN111773139A CN 111773139 A CN111773139 A CN 111773139A CN 202010541304 A CN202010541304 A CN 202010541304A CN 111773139 A CN111773139 A CN 111773139A
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skin care
collagen
care product
stirring
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苗本武
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Shanghai Natures Biotechnology Co ltd
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Shanghai Natures Biotechnology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/00Cosmetics or similar toiletry preparations
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    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35Ketones, e.g. benzophenone
    • A61K8/355Quinones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
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    • A61K8/37Esters of carboxylic acids
    • A61K8/375Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/67Vitamins
    • A61K8/671Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • AHUMAN NECESSITIES
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    • A61K8/67Vitamins
    • A61K8/676Ascorbic acid, i.e. vitamin C
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    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/925Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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Abstract

The invention discloses a skin care product for promoting RNA transcription, which comprises the following components in parts by mass: 2.3-5.1 parts of triglyceride decanoate, 4-6 parts of squalane, 2-3.6 parts of ethyl hexyl palmitate, 5-7.3 parts of isopropyl myristate, 3.2-4.4 parts of mink oil, 1.3-3.3 parts of PEG-7 glyceryl cocoate, 20-40.8 parts of deionized water, 5-7 parts of algal oligosaccharins, 7-10 parts of glycerol, 2.3-3.6 parts of microorganism C, 5.5-8.6 parts of retinol, 3.8-6.5 parts of peptide, 103.3-4.5 parts of coenzyme Q, 20-30 parts of recombinant human III-like collagen and 131.5-3.4 parts of interleukin. The invention also provides a preparation process of the skin care product for promoting RNA transcription, which is characterized by comprising the following steps: s1, 2.3-5.1 parts of capric acid triglyceride, 4-6 parts of squalane, 2-3.6 parts of ethyl hexyl palmitate, 5-7.3 parts of isopropyl myristate, 3.2-4.4 parts of mink oil and 1.3-3.3 parts of PEG-7 glycerol cocoate, and starting steam for heating; s2; s3; s4; and S5. The invention has reasonable structure, can accelerate the transcription of the type III collagen gene, and the more the transcription is, the more the messenger RNA is generated, and the content of skin collagen is greatly improved.

Description

Skin care product for promoting RNA transcription and preparation process thereof
Technical Field
The invention relates to the technical field of skin care products, in particular to a skin care product for promoting RNA transcription and a preparation process thereof.
Background
Skin care products, i.e. products for protecting the skin. With the continuous progress of social economy and the abundance of material life, the skin care product is no longer a thing which is only used by abundant people in the past. Skin care products are now moving into the homes of ordinary people. It plays a great role in improving the spirit and the image of people.
Particularly, in the anti-aging field, a cell nucleus is arranged in the center of a human cell, 46 DNA (deoxyribonucleic acid) chains are arranged in the cell nucleus, and each DNA chain contains a large number of gene segments. The information in the gene segment can be transcribed into messenger RNA, the messenger RNA enters cytoplasm and is translated into a peptide chain, and the peptide chain is folded and assembled to generate protein. The source of skin elasticity is type III collagen; the skin care product is assembled by peptide chains derived from a plurality of genes, and the current skin care products cannot essentially solve the problem of inhibiting skin aging.
Disclosure of Invention
The invention aims to solve the defects in the prior art and provides a skin care product for promoting RNA transcription and a preparation process thereof.
In order to achieve the purpose, the invention adopts the following technical scheme:
a skin care product for promoting RNA transcription comprises the following components in parts by mass: 2.3-5.1 parts of triglyceride decanoate, 4-6 parts of squalane, 2-3.6 parts of ethyl hexyl palmitate, 5-7.3 parts of isopropyl myristate, 3.2-4.4 parts of mink oil, 1.3-3.3 parts of PEG-7 glyceryl cocoate, 20-40.8 parts of deionized water, 5-7 parts of algal oligosaccharins, 7-10 parts of glycerol, 2.3-3.6 parts of microorganism C, 5.5-8.6 parts of retinol, 3.8-6.5 parts of peptide, 103.3-4.5 parts of coenzyme Q, 20-30 parts of recombinant human III-like collagen and 131.5-3.4 parts of interleukin.
Preferably, 2.3-5.1 parts of triglyceride decanoate, 4-6 parts of squalane, 2-3.6 parts of ethyl hexyl palmitate, 5-7.3 parts of isopropyl myristate, 3.2-4.4 parts of mink oil and 1.3-3.3 parts of PEG-7 glyceryl cocoate are oil phase components.
Preferably, the deionized water 20-40.8, the algal oligosaccharins 5-7 and the glycerol 7-10 are water phase components.
A preparation process of a skin care product for promoting RNA transcription comprises the following steps:
s1, 2.3-5.1 parts of capric acid triglyceride, 4-6 parts of squalane, 2-3.6 parts of ethyl hexyl palmitate, 5-7.3 parts of isopropyl myristate, 3.2-4.4 parts of mink oil and 1.3-3.3 parts of PEG-7 glyceryl cocoate, starting steam for heating, heating to 70-75 ℃ under the condition of continuous stirring, and fully melting or uniformly dissolving the materials for later use;
s2, adding deionized water into a jacket dissolving pot, adding 20-40.8 parts of deionized water as water-soluble components, 5-7 parts of algal oligosaccharins and 7-10 parts of glycerol into the jacket dissolving pot, heating to 90-100 ℃ under stirring, maintaining for 20min for sterilization, and cooling to 70-80 ℃ for later use;
s3, preheating an emulsifying pot to 60-70 ℃, vacuumizing, sucking the liquid in S1 and S2, adding water phase liquid, adding oil phase liquid at a uniform speed, homogenizing and stirring at the stirring speed of 30r/min, and emulsifying for 40-60 min;
s4, degassing and cooling, adding 2.3-3.6 parts of microorganism C, 5.5-8.6 parts of retinol, 3.8-6.5 parts of peptide, 103.3-4.5 parts of coenzyme Q, 20-30 parts of recombinant human III type human collagen and 131.5-3.4 parts of interleukin when cooling to 30-45 ℃, and stirring and continuously cooling to 20-30 ℃;
s5, standing and aging for 24-48 h, discharging and filling to obtain the finished product.
Preferably, excessive heating and long-term heating are avoided to prevent oxidative deterioration of raw material components, and easily-oxidizable oil components, preservatives and emulsifiers are added to the oil phase before emulsification, and are dissolved uniformly, thereby carrying out emulsification.
Preferably, the interleukin 13, coenzyme Q10, microorganism C are capable of accelerating transcription of type III collagen gene.
Compared with the prior art, the invention has the beneficial effects that:
1. can accelerate the transcription of the type III collagen gene, the more the transcription is, the more messenger RNA is generated, the content of skin collagen is also greatly improved, thereby fundamentally inhibiting the aging of the skin.
2. The microbe C, besides being a necessary cofactor in the collagen production process, is also an element for forming the collagen, and can promote the synthesis and absorption of the collagen, prevent the loss of a large amount of the collagen caused by free radicals, inhibit enzymes for decomposing the collagen after the retinol is converted into retinoic acid in a human body, promote the generation of new collagen and peptide, stimulate the growth of the collagen, resist the free radicals, increase the skin thickness, eliminate wrinkles and improve the moisture content of the skin.
Detailed Description
In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein, but rather should be construed as broadly as the present invention is capable of modification in various respects, all without departing from the spirit and scope of the present invention.
Example 1
A skin care product for promoting RNA transcription comprises the following components in parts by mass: triglyceride of decanoic acid 2.3, squalane 4, ethyl hexyl palmitate 2, isopropyl myristate 5, mink oil 3.2, PEG-7 glyceryl cocoate 1.3, deionized water 20, algal oligosaccharin 5, glycerol 7, microorganism C2.3-, retinol 5.5, peptide 3.8, coenzyme Q103.3, recombinant human collagen III 20 and interleukin 131.5.
A preparation process of a skin care product for promoting RNA transcription comprises the following steps:
s1, 2.3 parts of capric acid triglyceride, 4 parts of squalane, 2 parts of ethyl hexyl palmitate, 5 parts of isopropyl myristate, 3.2 parts of mink oil and 1.3 parts of PEG-7 glyceryl cocoate, starting steam for heating, and heating to 70 ℃ under the condition of continuous stirring to fully melt or uniformly dissolve the materials for later use;
s2, adding deionized water into a jacket dissolving pot, adding water-soluble components of deionized water 20, algal oligosaccharin 5 and glycerol 7 into the jacket dissolving pot, heating to 90 ℃ under stirring, maintaining for 20min for sterilization, and cooling to 70 ℃ for later use;
s3, preheating an emulsifying pot to 60 ℃, vacuumizing, sucking the liquid in S1 and S2, adding the water phase liquid, adding the oil phase liquid at a uniform speed, homogenizing and stirring at the stirring speed of 30r/min, and emulsifying for 40 min;
s4, degassing and cooling, adding microorganism C2.3, retinol 5.5, peptide 3.8, coenzyme Q103.3, recombinant human III type human collagen 20 and interleukin 131.5 when cooling to 30 ℃, stirring and continuously cooling to 20 ℃;
s5, standing and aging for 24h, discharging and filling, and finally obtaining the finished product.
Example 2
A skin care product for promoting RNA transcription comprises the following components in parts by mass: 2.6 parts of capric acid triglyceride, 4.5 parts of squalane, 2.6 parts of ethyl hexyl palmitate, 6.3 parts of isopropyl myristate, 3.5 parts of mink oil, 1.8 parts of PEG-7 glyceryl cocoate, 28 parts of deionized water, 5.5 parts of algal oligosaccharins, 8 parts of glycerol, 2.5 parts of microorganism, 5.9 parts of retinol, 4 parts of victory peptide, 103.8 parts of coenzyme Q, 23 parts of recombinant human III type human collagen and 131.8 parts of interleukin.
A preparation process of a skin care product for promoting RNA transcription comprises the following steps:
s1, 2.6 parts of capric acid triglyceride, 4.5 parts of squalane, 2.6 parts of ethyl hexyl palmitate, 6.3 parts of isopropyl myristate, 3.5 parts of mink oil and 1.8 parts of PEG-7 glyceryl cocoate, starting steam for heating, and heating to 72 ℃ under the condition of continuous stirring to fully melt or uniformly dissolve the materials for later use;
s2, adding deionized water into a jacket dissolving pot, adding 5.5 parts of water-soluble components, namely, trehalose oligosaccharide and 8 parts of glycerol, stirring, heating to 93 ℃, maintaining for 20min for sterilization, and cooling to 73 ℃ for later use;
s3, preheating an emulsifying pot to 60-70 ℃, vacuumizing, sucking the liquid in S1 and S2, adding water phase liquid, adding oil phase liquid at a uniform speed, homogenizing and stirring at a stirring speed of 30r/min, and emulsifying for 45 min;
s4, degassing and cooling, adding microorganism C2.5, retinol 5.9, peptide 4, coenzyme Q103.8, recombinant human III type human collagen 23 and interleukin 131.8 when cooling to 35 ℃, and stirring and continuously cooling to 23 ℃;
s5, standing and aging for 28h, discharging and filling, and finally obtaining the finished product.
Example 3
A skin care product for promoting RNA transcription comprises the following components in parts by mass: triglyceride of decanoic acid 4, squalane 5, ethyl hexyl palmitate 3, isopropyl myristate 7, mink oil 4, PEG-7 glycerol cocoate 3, deionized water 40, algal oligosaccharin 6, glycerol 9, microorganism C3, retinol 7.8, peptide 5, coenzyme Q104, recombinant human III type human collagen 28 and interleukin 133.
A preparation process of a skin care product for promoting RNA transcription comprises the following steps:
s1, triglyceride of capric acid 4, squalane 5, ethyl hexyl palmitate 3, isopropyl myristate 7, mink oil 4 and PEG-7 glyceryl cocoate 3, starting steam for heating, and heating to 73 deg.C under continuously stirring to melt or dissolve completely;
s2, adding deionized water into a jacket dissolving pot, adding water-soluble components of deionized water 40, algal oligosaccharins 5-7 and glycerol 9 into the jacket dissolving pot, heating to 98 ℃ under stirring, maintaining for 20min for sterilization, and cooling to 78 ℃ for later use;
s3, preheating an emulsifying pot to 68 ℃, vacuumizing, sucking the liquid in S1 and S2, adding the water phase liquid, adding the oil phase liquid at a uniform speed, homogenizing and stirring at the stirring speed of 30r/min, and emulsifying for 50 min;
s4, degassing and cooling, adding microorganism C3, retinol 7.8, peptide 5, coenzyme Q104, recombinant human III type human collagen 28 and interleukin 133 when cooling to 40 ℃, and stirring and continuously cooling to 28 ℃;
s5, standing and aging for 35h, discharging and filling, and finally obtaining the finished product.
Example 4
A skin care product for promoting RNA transcription comprises the following components in parts by mass: 4.1 parts of triglyceride decanoate, 5.1 parts of squalane, 3.1 parts of ethyl hexyl palmitate, 7.1 parts of isopropyl myristate, 4.1 parts of mink oil, 3.1 parts of PEG-7 glyceryl cocoate, 40.1 parts of deionized water, 6.1 parts of algal oligosaccharin, 9.1 parts of glycerol, 3.1 parts of microorganism C, 8 parts of retinol, 5.1 parts of peptide, 104.2 parts of coenzyme Q, 29 parts of recombinant human III type human collagen and 133.5 parts of interleukin.
A preparation process of a skin care product for promoting RNA transcription comprises the following steps:
s1, 4.1 parts of capric acid triglyceride, 5.1 parts of squalane, 3.1 parts of ethyl hexyl palmitate, 7.1 parts of isopropyl myristate, 4.1 parts of mink oil and 3.1 parts of PEG-7 glyceryl cocoate, starting steam for heating, and heating to 74 ℃ under the condition of continuous stirring to fully melt or uniformly dissolve the materials for later use;
s2, adding deionized water into a jacket dissolving pot, adding water-soluble components, namely, the trehalose oligosaccharide 6.1 and the glycerol 9.1 into the jacket dissolving pot, heating to 99 ℃ under stirring, maintaining for 20min for sterilization, and then cooling to 79 ℃ for later use;
s3, preheating an emulsifying pot to 69 ℃, vacuumizing, sucking the liquid in S1 and S2, adding the water phase liquid, adding the oil phase liquid at a uniform speed, homogenizing and stirring at the stirring speed of 30r/min, and emulsifying for 55 min;
s4, degassing and cooling, adding microorganism C3.1, retinol 8, peptide 5.1, coenzyme Q104.2, recombinant human III type human collagen 29 and interleukin 133.5 when cooling to 42 ℃, and stirring and continuously cooling to 29 ℃;
s5, standing and aging for 40h, discharging and filling to obtain the final product
Example 5
A skin care product for promoting RNA transcription comprises the following components in parts by mass: 5.1 parts of triglyceride decanoate, 6 parts of squalane, 3.6 parts of ethyl hexyl palmitate, 7.3 parts of isopropyl myristate, 4.4 parts of mink oil, 3.3 parts of PEG-7 glyceryl cocoate, 40.8 parts of deionized water, 7 parts of algal oligosaccharin, 10 parts of glycerol, 3.6 parts of microorganism C, 8.6 parts of retinol, 6.5 parts of peptide, 104.5 parts of coenzyme Q, 30 parts of recombinant human III type human collagen and 133.4 parts of interleukin.
A preparation process of a skin care product for promoting RNA transcription comprises the following steps:
s1, 5.1 parts of capric acid triglyceride, 6 parts of squalane, 3.6 parts of ethyl hexyl palmitate, 7.3 parts of isopropyl myristate, 4.4 parts of mink oil and 3.3 parts of PEG-7 glycerin cocoate, starting steam for heating, and heating to 70-75 ℃ under the condition of continuous stirring to ensure that the materials are fully melted or uniformly dissolved for later use;
s2, adding deionized water into a jacket dissolving pot, adding water-soluble components, namely, the algal oligosaccharin 7 and the glycerol 10, into the pot, heating to 100 ℃ under stirring, maintaining for 20min for sterilization, and then cooling to 80 ℃ for later use;
s3, preheating an emulsifying pot to 70 ℃, vacuumizing, sucking the liquid in S1 and S2, adding the water phase liquid, adding the oil phase liquid at a uniform speed, homogenizing and stirring at the stirring speed of 30r/min, and emulsifying for 60 min;
s4, degassing and cooling, adding microorganism C3.6, retinol 8.6, peptide 6.5, coenzyme Q104.5, recombinant human III type human collagen 30 and interleukin 133.4 when cooling to 45 ℃, stirring and continuously cooling to 30 ℃;
s5, standing and aging for 48h, discharging and filling, and finally obtaining the finished product.
In the invention, the triglyceride of decanoic acid, squalane, ethyl hexyl palmitate, isopropyl myristate, mink oil and PEG-7 glyceryl cocoate are oil phase components; the deionized water, the seaweed oligosaccharin and the glycerol are water phase components; excessive heating and long-time heating are avoided to prevent the raw material components from oxidative deterioration, and oil phase, preservative and emulsifier which are easy to oxidize can be added before emulsification, and are dissolved uniformly to carry out emulsification; the interleukin 13, coenzyme Q10 and microorganism C can accelerate the transcription of type III collagen gene.
In the invention, interleukin 13 and coenzyme Q10 can accelerate the transcription of type III collagen gene, the more the transcription, the more messenger RNA is generated, the more the content of skin collagen is greatly improved, thus fundamentally inhibiting the aging of skin, microorganism C is not only a necessary cofactor in the manufacturing process of collagen, but also an element forming collagen, and can also promote the synthesis and absorption of collagen, prevent the loss of collagen caused by free radicals, inhibit the ferment for decomposing collagen after retinol is converted into retinoic acid in human body, promote the generation of new collagen and peptide, stimulate the growth of collagen, resist free radicals, increase the thickness of skin and eliminate wrinkles. Meanwhile, the composition has similar effects of 7 peptides and oligopeptides, and the peptides and oligopeptides can promote the growth of collagen and improve the moisture content of skin.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.

Claims (6)

1. A skin care product for promoting RNA transcription is characterized by comprising the following components in parts by mass: 2.3-5.1 parts of triglyceride decanoate, 4-6 parts of squalane, 2-3.6 parts of ethyl hexyl palmitate, 5-7.3 parts of isopropyl myristate, 3.2-4.4 parts of mink oil, 1.3-3.3 parts of PEG-7 glyceryl cocoate, 20-40.8 parts of deionized water, 5-7 parts of algal oligosaccharins, 7-10 parts of glycerol, 2.3-3.6 parts of microorganism C, 5.5-8.6 parts of retinol, 3.8-6.5 parts of peptide, 103.3-4.5 parts of coenzyme Q, 20-30 parts of recombinant human III-like collagen and 131.5-3.4 parts of interleukin.
2. The skin care product for promoting RNA transcription as claimed in claim 1, wherein the triglyceride decanoate 2.3-5.1, squalane 4-6, ethyl hexyl palmitate 2-3.6, isopropyl myristate 5-7.3, mink oil 3.2-4.4, and PEG-7 glyceryl cocoate 1.3-3.3 are oil phase components.
3. The skin care product for promoting RNA transcription according to claim 1, wherein the deionized water 20-40.8, the algal oligosaccharins 5-7 and the glycerol 7-10 are water phase components.
4. A preparation process of a skin care product for promoting RNA transcription is characterized by comprising the following steps:
s1, 2.3-5.1 parts of capric acid triglyceride, 4-6 parts of squalane, 2-3.6 parts of ethyl hexyl palmitate, 5-7.3 parts of isopropyl myristate, 3.2-4.4 parts of mink oil and 1.3-3.3 parts of PEG-7 glyceryl cocoate, starting steam for heating, heating to 70-75 ℃ under the condition of continuous stirring, and fully melting or uniformly dissolving the materials for later use;
s2, adding deionized water into a jacket dissolving pot, adding 20-40.8 parts of deionized water as water-soluble components, 5-7 parts of algal oligosaccharins and 7-10 parts of glycerol into the jacket dissolving pot, heating to 90-100 ℃ under stirring, maintaining for 20min for sterilization, and cooling to 70-80 ℃ for later use;
s3, preheating an emulsifying pot to 60-70 ℃, vacuumizing, sucking the liquid in S1 and S2, adding water phase liquid, adding oil phase liquid at a uniform speed, homogenizing and stirring at the stirring speed of 30r/min, and emulsifying for 40-60 min;
s4, degassing and cooling, adding 2.3-3.6 parts of microorganism C, 5.5-8.6 parts of retinol, 3.8-6.5 parts of peptide, 103.3-4.5 parts of coenzyme Q, 20-30 parts of recombinant human III type human collagen and 131.5-3.4 parts of interleukin when cooling to 30-45 ℃, and stirring and continuously cooling to 20-30 ℃;
s5, standing and aging for 24-48 h, discharging and filling to obtain the finished product.
5. The process of claim 4, wherein the oil phase, the preservative and the emulsifier which are easily oxidized can be added before emulsification, and the emulsion can be dissolved uniformly.
6. The process of claim 4, wherein the interleukin 13, coenzyme Q10 and microorganism C are capable of accelerating transcription of type III collagen gene.
CN202010541304.4A 2020-06-15 2020-06-15 Skin care product for promoting RNA transcription and preparation process thereof Pending CN111773139A (en)

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CN113456522A (en) * 2021-05-19 2021-10-01 太原理工大学 Hand cream with recombinant human collagen as nutrient component and preparation method thereof

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KR20140078973A (en) * 2012-12-18 2014-06-26 (주)아모레퍼시픽 Skin external composition interleukin 13
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CN112932990A (en) * 2021-04-15 2021-06-11 广州樊文花化妆品有限公司 Anti-aging composition and preparation method and application thereof
CN113456522A (en) * 2021-05-19 2021-10-01 太原理工大学 Hand cream with recombinant human collagen as nutrient component and preparation method thereof

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