WO2013058594A3 - Method for preparing a fermented deer antler extract having an anti-inflammatory activity, extract obtained by the method and use of such extract - Google Patents

Method for preparing a fermented deer antler extract having an anti-inflammatory activity, extract obtained by the method and use of such extract Download PDF

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Publication number
WO2013058594A3
WO2013058594A3 PCT/KR2012/008588 KR2012008588W WO2013058594A3 WO 2013058594 A3 WO2013058594 A3 WO 2013058594A3 KR 2012008588 W KR2012008588 W KR 2012008588W WO 2013058594 A3 WO2013058594 A3 WO 2013058594A3
Authority
WO
WIPO (PCT)
Prior art keywords
extract
deer antler
preparing
resultant material
inflammatory activity
Prior art date
Application number
PCT/KR2012/008588
Other languages
French (fr)
Korean (ko)
Other versions
WO2013058594A2 (en
Inventor
정창휘
최학주
김동희
Original Assignee
(주)메레데코리아
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by (주)메레데코리아 filed Critical (주)메레데코리아
Priority to CN201280058853.XA priority Critical patent/CN104105492B/en
Publication of WO2013058594A2 publication Critical patent/WO2013058594A2/en
Publication of WO2013058594A3 publication Critical patent/WO2013058594A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/062—Ascomycota
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment

Abstract

The present invention relates to a method for preparing a fermented deer antler extract having an anti-inflammatory activity, an extract obtained by the method and to the use of such extract. The method comprises :a step (step 1) of adding purified water to chopped deer antler and performing hot water extraction and filtering on the resultant material; a step (step 2) of adding a culture solution for Bacillus sp. strain to the liquid content obtained in step 1 and fermenting the resultant material to obtain a first fermented liquid extract; and a step (step 3) of adding purified water to the solid content of deer antler obtained in the first step, adding a culture solution for Aspergiullus sp. strain to the resultant material and fermenting the resultant material to obtain a second fermented liquid extract. According to the present invention, deer antler extracts can be prepared by the most environmentally-friendly fermentation, destruction of physiological active substance of deer antler is reduced while increasing the content of active ingredient, and productivity can be also improved. Therefore, the method of the present invention can be valuably used as a method for preparing deer antler extracts which may be used in various fields. Particularly, the method of the present invention systematically discloses an anti-inflammatory activity, and therefore, can be suitably and widely used in foods, cosmetics, etc.
PCT/KR2012/008588 2011-10-20 2012-10-19 Method for preparing a fermented deer antler extract having an anti-inflammatory activity, extract obtained by the method and use of such extract WO2013058594A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201280058853.XA CN104105492B (en) 2011-10-20 2012-10-19 The purposes of the fermentation preparation method of deer antler extract, thus obtained extract and the extract with anti-inflammatory activity

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020110107597A KR101169775B1 (en) 2011-10-20 2011-10-20 A method for preparing fermented young antler extract having an anti-inflammatory activity, a extract therefrom and use of the extract
KR10-2011-0107597 2011-10-20

Publications (2)

Publication Number Publication Date
WO2013058594A2 WO2013058594A2 (en) 2013-04-25
WO2013058594A3 true WO2013058594A3 (en) 2013-06-20

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2012/008588 WO2013058594A2 (en) 2011-10-20 2012-10-19 Method for preparing a fermented deer antler extract having an anti-inflammatory activity, extract obtained by the method and use of such extract

Country Status (3)

Country Link
KR (1) KR101169775B1 (en)
CN (1) CN104105492B (en)
WO (1) WO2013058594A2 (en)

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KR101761006B1 (en) * 2015-07-29 2017-07-26 (주)엠앤씨생명과학 Osmotic Enzyme Fermentation
KR101750620B1 (en) * 2015-09-11 2017-06-27 (주)엠앤씨생명과학 Preparation method of osmotic enzyme fermentation product using dendranthema zawadskii, the fermentation product prepared thereby and cosmetic, food or pharmaceutical composition comprising the same
KR101750619B1 (en) * 2015-09-11 2017-06-27 (주)엠앤씨생명과학 Preparation method of osmotic enzyme fermentation product using momordica charantia and houttuynia cordata, the fermentation product prepared thereby and cosmetic, food or pharmaceutical composition comprising the same
CN105105130A (en) * 2015-09-17 2015-12-02 辽阳千山呈龙科技有限公司 Method for processing velvet antler enzyme
KR101776686B1 (en) * 2016-08-26 2017-09-08 유창우 Process for preparing solid formulation of deer antlers fermenting material having high ganglioside contents
KR102033501B1 (en) 2019-03-06 2019-11-29 ㈜바이오션 Fermented hydrolsate of deer antlers with increased chondroitin sulfate contents, manufactruing method thereof, and foods containing thereof
KR102227709B1 (en) * 2019-04-09 2021-03-12 최학주 a fermented antler composite with the function of the immunity boosting and the production method
CN110876378A (en) * 2019-12-11 2020-03-13 利民化学有限责任公司 Intelligent microcapsule suspending agent and preparation method thereof
CN111812333A (en) * 2020-06-29 2020-10-23 吉林省东北亚生物科技有限公司 Method for comparing activity of ligamentum cervi natural peptide and enzymatic hydrolysis peptide on resisting rheumatoid arthritis
CN112494518A (en) * 2020-11-18 2021-03-16 中科健康产业集团股份有限公司 Preparation method of pilose antler wine
KR102441355B1 (en) 2021-11-11 2022-09-07 주식회사 바이오케어 Method for producing velvet antler extracts with enhanced ganglioside content
KR102621766B1 (en) * 2021-11-26 2024-01-12 한국양토양록축산업협동조합 Method for producing fermented antler extract having anti-aging, antibacterial and anti-inflammatory activity, extract obtained therefrom, and use of such extract

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR920003960A (en) * 1990-08-31 1992-03-27 정형식 Method of manufacturing stabilized drinks
WO2001043548A1 (en) * 1999-12-17 2001-06-21 Agrofresh Inc. Synthesis methods, complexes and delivery methods for the safe and convenient storage, transport and application of compounds for inhibiting the ethylene response in plants
KR100972116B1 (en) * 2009-10-29 2010-07-23 (주)한국파비스 알엔디 Method of producing fermentation of herbal medicine, the fermentation produced thereby, and food comprising the fermentation
KR20100090514A (en) * 2009-02-06 2010-08-16 (주)아모레퍼시픽 Food composition for accelerating the growth
KR20110106759A (en) * 2010-03-23 2011-09-29 광동제약 주식회사 Composition for enhancement of immune function and improvement of hematopoiesis which comprises antler fermented with bacillus subtilis kctc 11454bp as an active ingredient, and a preparation method thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR920003960A (en) * 1990-08-31 1992-03-27 정형식 Method of manufacturing stabilized drinks
WO2001043548A1 (en) * 1999-12-17 2001-06-21 Agrofresh Inc. Synthesis methods, complexes and delivery methods for the safe and convenient storage, transport and application of compounds for inhibiting the ethylene response in plants
KR20100090514A (en) * 2009-02-06 2010-08-16 (주)아모레퍼시픽 Food composition for accelerating the growth
KR100972116B1 (en) * 2009-10-29 2010-07-23 (주)한국파비스 알엔디 Method of producing fermentation of herbal medicine, the fermentation produced thereby, and food comprising the fermentation
KR20110106759A (en) * 2010-03-23 2011-09-29 광동제약 주식회사 Composition for enhancement of immune function and improvement of hematopoiesis which comprises antler fermented with bacillus subtilis kctc 11454bp as an active ingredient, and a preparation method thereof

Also Published As

Publication number Publication date
CN104105492A (en) 2014-10-15
WO2013058594A2 (en) 2013-04-25
KR101169775B1 (en) 2012-07-31
CN104105492B (en) 2017-12-05

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