CN102438630A - 治疗抑郁症的药物组合物、制备方法及用途 - Google Patents

治疗抑郁症的药物组合物、制备方法及用途 Download PDF

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CN102438630A
CN102438630A CN2009801593834A CN200980159383A CN102438630A CN 102438630 A CN102438630 A CN 102438630A CN 2009801593834 A CN2009801593834 A CN 2009801593834A CN 200980159383 A CN200980159383 A CN 200980159383A CN 102438630 A CN102438630 A CN 102438630A
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CN102438630B (zh
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张作光
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Alternative & Traditional Medicine (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
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  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

本发明涉及一种治疗抑郁症的药物组合物，所述药物组合物由甘草和白芍或它们的提取物制成，含有甘草酸或甘草次酸，芍药苷和芍药内酯苷等。本发明还涉及所述药物组合物的制备方法及在制备治疗抑郁症及其并发疾病、障碍的药物、保健食品和/或营养剂中的用途。

Description

PCT国内申请，说明书已公开。

Claims (1)

  1. PCT国内申请，权利要求书已公开。
CN200980159383.4A 2009-05-21 2009-12-09 治疗抑郁症的药物组合物、制备方法及用途 Expired - Fee Related CN102438630B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN200980159383.4A CN102438630B (zh) 2009-05-21 2009-12-09 治疗抑郁症的药物组合物、制备方法及用途

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CN2009101433362 2009-05-21
CN2009101433362A CN101890082A (zh) 2009-05-21 2009-05-21 一组用于治疗抑郁症的药物组合物及制法
CN200910143336.2 2009-05-21
CN200980159383.4A CN102438630B (zh) 2009-05-21 2009-12-09 治疗抑郁症的药物组合物、制备方法及用途
PCT/CN2009/001409 WO2010133015A1 (zh) 2009-05-21 2009-12-09 治疗抑郁症的药物组合物、制备方法及用途

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CN102438630A true CN102438630A (zh) 2012-05-02
CN102438630B CN102438630B (zh) 2015-03-18

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CN200980159383.4A Expired - Fee Related CN102438630B (zh) 2009-05-21 2009-12-09 治疗抑郁症的药物组合物、制备方法及用途

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107184866A (zh) * 2017-06-01 2017-09-22 泉州医学高等专科学校 一种芍甘复方胶囊剂的制备工艺

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EP2644198B1 (en) 2010-11-25 2017-04-12 Zuoguang Zhang Antianxiety and sleep disorder improving use of albiflorin
CN103242393A (zh) * 2013-05-13 2013-08-14 兰州理工大学 大孔树脂分离甘草酸提取液分离纯化方法
FR3033699B1 (fr) * 2015-03-16 2018-07-27 Crodarom Extrait de pivoine de chine, composition comprenant ledit extrait et utilisation cosmetique
EP3370737B1 (en) * 2015-11-04 2021-09-22 Prescient Pharma LLC Anti-aging compositions and methods for using same
CN105477126A (zh) * 2015-12-30 2016-04-13 广东药学院 一种用于治疗抑郁症的中药提取物组合物及其制备方法和应用
CN107397752A (zh) 2016-10-11 2017-11-28 张作光 芍药内酯苷在制备改善肠道菌群系统功能的产品中的用途
CN107412244A (zh) * 2016-10-11 2017-12-01 张作光 芍药内酯苷在制备改善褪黑素系统功能的产品中的用途
CN112438994A (zh) * 2019-08-29 2021-03-05 鲁南制药集团股份有限公司 一种对双相情感障碍具有防治作用的小肠粘膜提取物
CN110652004A (zh) * 2019-08-29 2020-01-07 北京康爱营养医学研究院 一种防治抑郁的营养组合物及其制备方法、应用
CN114272254B (zh) * 2020-09-28 2024-01-26 中国科学院上海药物研究所 甘草次酸和芍药苷的组合在治疗肝损伤、肝纤维化中的应用
CN112057526A (zh) * 2020-09-29 2020-12-11 浙江省中医药研究院 一种健脾解郁合剂

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CN101099770A (zh) * 2006-07-04 2008-01-09 北京中医药大学 一种具有咪唑啉受体激动活性的药物组合物及制备方法和应用

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107184866A (zh) * 2017-06-01 2017-09-22 泉州医学高等专科学校 一种芍甘复方胶囊剂的制备工艺

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WO2010133015A1 (zh) 2010-11-25
CN102438630B (zh) 2015-03-18

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