CN102397510A - Compound propolis composition for treating chicken Marek's disease and preparation method thereof - Google Patents
Compound propolis composition for treating chicken Marek's disease and preparation method thereof Download PDFInfo
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- CN102397510A CN102397510A CN2011103606664A CN201110360666A CN102397510A CN 102397510 A CN102397510 A CN 102397510A CN 2011103606664 A CN2011103606664 A CN 2011103606664A CN 201110360666 A CN201110360666 A CN 201110360666A CN 102397510 A CN102397510 A CN 102397510A
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Abstract
The invention discloses a compound propolis composition for treating the chicken Marek's disease and a preparation method thereof, relating to the field of animal medicaments. The preparation method of the composition comprises the following steps of: (1) performing ultrafine smashing on various components in a formula respectively, and sieving with a 700-mesh sieve; (2) weighing 15-35 parts by weight of propolis, 10-30 parts by weight of Chinese atractylodes and 15-35 parts by weight of tall gastrodia tuber, and mixing for 5-10 minutes to uniform state; (3) weighing 10-35 parts by weight of astragalus, 10-35 parts by weight of curcuma zedoary, 15-45 parts by weight of isatis root and 10-30 parts by weight of cortex eucommiae, and mixing for 5-10 minutes to uniform state; and (4) combining the compositions obtained in the steps (2) and (3), and continually mixing for 10-15 minutes to uniform state. The preparation method has the beneficial effects of reasonable formula and easiness for preparing; the composition has the advantages of no toxic or side effect, environmental friendliness, no medicament residue, no medicament tolerance, ultrafine smashing, high bioavailability and remarkable curative effect; and as proved by clinical application, the compound propolis composition has a special treatment effect on the chicken Marek's disease.
Description
Technical field
The present invention relates to the animal field of medicaments, particularly a kind of compound bee-glue composition of treating chicken Marek's disease and preparation method thereof.
Background technology
Chicken Marek's disease be by chicken Marek's disease virus cause a kind of be main viral oncosis with lymphadenosis.Main infringement peripheral nervous system is a characteristic with the independent or multiple monocyte infiltration of peripheral nerve, gonad, iris, internal organs, muscle and skin.This disease has hyperinfection property, also is a kind of immunosuppressive disease.The chicken of the various length of times and kind all can infect, and mortality rate generally between 5%-60%, can influence growth and the egg laying performance of poultry.This disease all can take place throughout the year, is one of principal disease of harm poultry husbandry.
The pathogen of primary disease is a chicken Marek's disease virus, and virus resistance to external world is very strong.This disease almost spreads all over all countries of raising chickens of the world, distributes very extensively.At present, prevent and treat this disease the most frequently used be anti virus herb and Western medicine, Chinese medicine is because its prescription is unreasonable or just simple the pulverizing, and particle diameter is excessive, and drug release is slower, causes its bioavailability lower, clinical effectiveness is not fine; And the various antiviral drugs such as the Ministry of Agriculture such as ribavirin, amantadine ban use of.
Therefore researching and developing a kind of drug residue free of chicken Marek's disease, generations that have no drug resistance, the significant specific medicament of clinical effectiveness of treating is one of this field scientific research technical staff urgency new problem to be solved.
Summary of the invention
The objective of the invention is to overcome above-mentioned weak point, provide that a kind of reasonable recipe, preparation are simple, micronizing, bioavailability are high, effect obviously, have no drug resistance and the compound bee-glue composition of effective treatment Marek of drug residue and preparation method thereof.
For realizing above-mentioned purpose; The embodiment that the present invention adopted is following: a kind of compound bee-glue composition of treating chicken Marek's disease, by following component by weight mixed preparing form: propolis 15-35 part, Rhizoma Atractylodis 10-30 part, Rhizoma Gastrodiae 15-35 part, Radix Astragali 10-35 part, Rhizoma Curcumae 10-35 part, Radix Isatidis 15-45 part, Cortex Eucommiae 10-30 part.
Said various component optimum ratio amount is: 25 parts of propolis, 20 parts of Rhizoma Atractylodis, 25 parts in Rhizoma Gastrodiae, 25 parts of the Radixs Astragali, 25 parts of Rhizoma Curcumae, 35 parts of Radix Isatidis, 20 parts of the Cortexs Eucommiae.
A kind of method for preparing of treating the compound bee-glue composition of chicken Marek's disease, carry out as follows:
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing propolis 15-35 part, Rhizoma Atractylodis 10-30 part, Rhizoma Gastrodiae 15-35 part by weight, mix 5-10 minute to even;
(3) take by weighing Radix Astragali 10-35 part, Rhizoma Curcumae 10-35 part, Radix Isatidis 15-45 part, Cortex Eucommiae 10-30 part by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
The medicinal property of each component is following:
Propolis: bitter, hot, cold, return spleen, stomach warp, have the function of anti-inflammation, antalgesic-antipruritic, promotion tissue regeneration, raising immunity, antiallergic oxidation, hemostasis, protection gastrointestinal mucosa.
Radix Isatidis: bitter, cold, GUIXIN, stomach warp have the function of heat-clearing and toxic substances removing, removing heat from blood sore-throat relieving; Cure mainly anemopyretic cold, laryngopharynx swelling and pain, aphtha of the mouth and tongue, skin ulcer general edema with yellowish skin poison etc.
Rhizoma Atractylodis: hot, bitter, warm, return spleen, stomach, Liver Channel, the function that have drying damp and strengthening spleen, expelling wind and cold, makes eye bright; Cure mainly have loose bowels, edema, anemofrigid-damp arthralgia, anemofrigid cold, nyctalopia etc.
The Radix Astragali: sweet, tepor, return spleen, lung meridian, have the function of tonifying Qi and lifting yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, expelling pus and toxin by strengthening QI, expelling pus and promoting granulation; Curing mainly asthenia of pulmonosplenic qi, sinking of QI of middle-JIAO, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle sore difficultly bursts, bursts for a long time and do not hold back etc.
Rhizoma Gastrodiae: sweet, flat, return Liver Channel, have the function of suppressing the hyperactive liver to relieve the wind syndrome, relieving spasm to stop pain; Cure mainly that convulsion with spasms, facial hemiparalysis, limbs are tetanic, anemofrigid-damp arthralgia etc.
Rhizoma Curcumae: hot, bitter, warm, return liver, spleen channel, have the function of broken silt removing food stagnancy, promoting the circulation of QI to relieve pain; Cure mainly stagnation of QI-blood, tripe abdominal distention and pain, accumulation of food in the stomach and intes tine due to indigestion, traumatic injury etc.
The Cortex Eucommiae: sweet, warm, return liver, kidney channel, have invigorating the liver and kidney, bone and muscle strengthening, antiabortive function; Cure mainly that lumbago due to renal deficiency, waist are unable, rheumatic arthralgia, frequent fetal movement etc.
More than all flavor Chinese medicine according to the Chinese medical theory compatible combination, to pathogenic microorganism and the clinical symptoms and the pathological change of chicken Marek's disease, bring into play the effect of treating both the principal and secondary aspects of a disease.
The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixes more even; Chinese medicine composition is pollution-free, no drug residue, have no drug resistance, and cost is low, and it is wide to draw materials, and micronizing, bioavailability are high, can also can drink water the curative effect highly significant by spice.The present invention is according to Chinese veterinarian's traditional theory; Optimize this seven flavors Chinese medicine, and make them form pure Chinese powder medicine according to optimum ratio, clinical practice proves; The treatment chicken Marek's disease there is specially good effect; And make its product meat reach nuisanceless requirement, satisfy the export standard of product, guaranteed that effectively people's is healthy.
The specific embodiment
Below in conjunction with preferred embodiment, to details are as follows according to the specific embodiment provided by the invention:
Embodiment 1
A kind of compound bee-glue composition of treating chicken Marek's disease and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing 150 parts of propolis, 100 parts of Rhizoma Atractylodis, 150 parts in Rhizoma Gastrodiae by weight, mix 5-10 minute to even;
(3) take by weighing 100 parts of the Radixs Astragali, 100 parts of Rhizoma Curcumae, 150 parts of Radix Isatidis, 100 parts of the Cortexs Eucommiae by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 2
A kind of compound bee-glue composition of treating chicken Marek's disease and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing 250 parts of propolis, 200 parts of Rhizoma Atractylodis, 250 parts in Rhizoma Gastrodiae by weight, mix 5-10 minute to even;
(3) take by weighing 200 parts of the Radixs Astragali, 250 parts of Rhizoma Curcumae, 300 parts of Radix Isatidis, 200 parts of the Cortexs Eucommiae by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 3
A kind of compound bee-glue composition of treating chicken Marek's disease and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing 350 parts of propolis, 300 parts of Rhizoma Atractylodis, 350 parts in Rhizoma Gastrodiae by weight, mix 5-10 minute to even;
(3) take by weighing 350 parts of the Radixs Astragali, 350 parts of Rhizoma Curcumae, 450 parts of Radix Isatidis, Cortex Eucommiae 10-30 part by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Clinical trial:
With the ill poultry of product feeding of the present invention etc., a day dose is: by the every 100g of the present invention, spice 120kg feeds, drinking-water 200kg, every day 2-3 time, logotype 3-5 day; Oral back reaches the purpose of treatment disease through gastrointestinal absorption.
Table is the field applicable cases contrast of the present invention and other medicines treatment chicken Marek's disease:
| Numbering | Group | Mortality rate % | Cure rate % | Symptom rate % is arranged during end |
| I | The blank group | 30.6 | 18.5 | 50.9 |
| II | Chicken Marek's disease looses and organizes | 11.9 | 67.6 | 20.5 |
| III | Chinese medicine composition of the present invention | 7.7 | 80.4 | 11.9 |
This clinical effectiveness is through statistical analysis, and present composition treatment group is loose to organize with chicken Marek's disease and compared difference extremely significantly (P＜0.01) aspect the cure rate.
Above-mentioned detailed description of compound bee-glue composition of this treatment chicken Marek's disease and preparation method thereof being carried out with reference to embodiment; Be illustrative rather than determinate; Can enumerate out several embodiment according to institute's limited range; Therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.
Claims (3)
1. compound bee-glue composition of treating chicken Marek's disease, it is characterized in that by following component by weight mixed preparing form: propolis 15-35 part, Rhizoma Atractylodis 10-30 part, Rhizoma Gastrodiae 15-35 part, Radix Astragali 10-35 part, Rhizoma Curcumae 10-35 part, Radix Isatidis 15-45 part, Cortex Eucommiae 10-30 part.
2. the compound bee-glue composition of treatment encephalomyelitis of chicken according to claim 1 is characterized in that said various component optimum ratio amount is: 25 parts of propolis, 20 parts of Rhizoma Atractylodis, 25 parts in Rhizoma Gastrodiae, 25 parts of the Radixs Astragali, 25 parts of Rhizoma Curcumae, 35 parts of Radix Isatidis, 20 parts of the Cortexs Eucommiae.
3. the method for preparing of the compound bee-glue composition of a treatment chicken Marek's disease according to claim 1 and 2 is characterized in that carrying out as follows:
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing propolis 15-35 part, Rhizoma Atractylodis 10-30 part, Rhizoma Gastrodiae 15-35 part by weight, mix 5-10 minute to even;
(3) take by weighing Radix Astragali 10-35 part, Rhizoma Curcumae 10-35 part, Radix Isatidis 15-45 part, Cortex Eucommiae 10-30 part by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
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| CN201110360666.4A CN102397510B (en) | 2011-11-15 | 2011-11-15 | Compound propolis composition for treating chicken Marek's disease and preparation method thereof |
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| CN201110360666.4A CN102397510B (en) | 2011-11-15 | 2011-11-15 | Compound propolis composition for treating chicken Marek's disease and preparation method thereof |
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| CN102397510A true CN102397510A (en) | 2012-04-04 |
| CN102397510B CN102397510B (en) | 2014-02-12 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105395810A (en) * | 2015-11-09 | 2016-03-16 | 巫溪县天赐良机养殖有限公司 | Traditional Chinese medicine composition for treating marek's disease |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1879686A (en) * | 2006-05-18 | 2006-12-20 | 天津生机集团有限公司 | A Chinese medicinal composition for treating avian viral disease and preparation method thereof |
| CN101062066A (en) * | 2007-05-29 | 2007-10-31 | 江西省百思特动物药业有限公司 | Compound isatis-root injection for animals and the preparing method thereof |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1879686A (en) * | 2006-05-18 | 2006-12-20 | 天津生机集团有限公司 | A Chinese medicinal composition for treating avian viral disease and preparation method thereof |
| CN101062066A (en) * | 2007-05-29 | 2007-10-31 | 江西省百思特动物药业有限公司 | Compound isatis-root injection for animals and the preparing method thereof |
Non-Patent Citations (4)
| Title |
|---|
| 曹礼华等: "中药对机体免疫功能影响研究进展", 《中兽医医药杂志》, no. 3, 30 June 2008 (2008-06-30), pages 28 - 30 * |
| 胡功政等: "《家禽常用药物及其合理使用》", 30 September 2010, article "病毒克", pages: 240 * |
| 黄中利等: "中草药添加剂在养禽生产中的应用", 《山东家禽》, no. 3, 31 March 2003 (2003-03-31), pages 49 - 53 * |
| 黄文诚: "蜂胶在食品保鲜和畜禽上的应用前景", 《中国蜂业》, vol. 57, no. 12, 31 December 2006 (2006-12-31), pages 25 - 26 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105395810A (en) * | 2015-11-09 | 2016-03-16 | 巫溪县天赐良机养殖有限公司 | Traditional Chinese medicine composition for treating marek's disease |
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