CN105395810A - Traditional Chinese medicine composition for treating marek's disease - Google Patents
Traditional Chinese medicine composition for treating marek's disease Download PDFInfo
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- CN105395810A CN105395810A CN201510755602.2A CN201510755602A CN105395810A CN 105395810 A CN105395810 A CN 105395810A CN 201510755602 A CN201510755602 A CN 201510755602A CN 105395810 A CN105395810 A CN 105395810A
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Abstract
The invention relates to a traditional Chinese medicine composition for treating the marek's disease. The traditional Chinese medicine composition is prepared from, by mass, 6-15 parts of cortex phellodendri, 15-25 parts of Chinese herbaceous peonies, 5-10 parts of propolis, 3-9 parts of folium artemisiae argyi, 6-15 parts of ephedra, 5-10 parts of rheum officinale, 6-15 parts of rhizoma atractylodis, 15-25 parts of bulbs of fritillary, 3-9 parts of radix trichosanthis, 6-15 parts of ginseng and 5-10 parts of astragalus. The invention further relate to application of the traditional Chinese medicine composition to treating the marek's disease. The traditional Chinese medicine composition starts from the pathology of the marek's disease and improves the conditions of excess and deficiency of yin and yang in the body, after trace mineral substance elements in medicine materials enter the body, the body can absorb effective components of the trace mineral substance elements and participate in metabolism of the body, the yin and yang, viscera and qi and blood balance of the body is regulated as a whole, and the disease is removed and the foundation is strengthened. A prepared traditional Chinese medicine composition capsule preparation is remarkable in treatment effect on the marek's disease of local chickens, the cure rate of the the marek's disease reaches up to 83%, and the remarkable efficiency reaches up to 88.5%.
Description
Technical field
The present invention relates to the field of Chinese medicines, be specially the Chinese medicine composition being used for the treatment of Marek.
Background technology
Marek has another name called neural lymphomatosis, is a kind of lymphoproliferative disease of chicken, with to the single or multiple histoorgan generation monocyte infiltrations of peripheral nervous, gonad, iris, various internal organs, muscle and skin for feature.Primary disease is the infectiousness oncosis caused by cell-associated herpesvirus, causes above-mentioned each Organ and tissue to form tumor.Sick chicken is common to become thin, limb paralysis, and often has acute death.Nosetiology can distinguish with other lymphoid tumors diseases of chicken.
Modern medicine, to clinical a certain symptom treatment, is often difficult to produce a desired effect, can not find suitable Therapeutic Method.The treatment means of Marek, is currently only vaccination and strengthens feeding and management, and treatment means is single and there is the hidden danger of immuning failure.Therefore, see a doctor in tcm treatment according to syndrome differentiation for Marek and be desirable thinking, although Chinese medicinal formulae conventional at present and dosage form have certain curative effect, but be not very desirable.It is different that various Chinese medicinal formulae may be limited to the concrete population profile observed, and the clinical observation of larger case load is not enough for a long time, causes curative effect very unstable, is difficult to promote and fixing prescription.
These situations show, existing medicine is for the treatment of Marek, and western medical treatment means used are single, and there is the risk of immuning failure; General facing with Chinese medicine is long for the course for the treatment of, DeGrain.So, and toxic and side effects little, inexpensive easy-to-use pharmaceutical preparation a kind of evident in efficacy, stable in the urgent need to developing.
Summary of the invention
In view of this, object of the present invention be exactly for above-mentioned clinical in existing treatment Marek Problems existing, a kind of convenient effective Chinese medicine composition is provided.The present invention is based on the principle of tcm treatment according to syndrome differentiation, a kind of Chinese medicine composition for the treatment of Marek evident in efficacy, with low cost is provided.From the pathology of Marek, improve the yin or yang excess situation partially declined in body, the QI and blood of the spleen and stomach regulating, Liver and kidney, make it battalion and unimpeded, after trace mineral element in spice enters body, its effective ingredient of body Absorbable rod participates in body metabolism, and the balance of conditioning human body negative and positive, internal organs and QI and blood, gets rid of illness and consolidate on the whole.Meanwhile, Chinese herbal medicine is little to body side effect, and energy treating both the principal and secondary aspects of a disease, so select treatment by Chinese herbs Marek, be effective selection.
The present invention selects Cortex Phellodendri, Radix Paeoniae, propolis, Folium Artemisiae Argyi, Herba Ephedrae, Radix Et Rhizoma Rhei, Rhizoma Atractylodis, Bulbus Fritillariae Uninbracteatae, Radix Trichosanthis, Radix Ginseng and the Radix Astragali 11 taste Chinese medicine to combine, according to the principle that Chinese medicine counteracts each other, by these medicine efficient combination, each efficacy of drugs is made to produce synergism, thus reach effect of heat clearing and damp drying, adjustment QI and blood, improve the yin or yang excess situation partially declined in body, taste, Liver and kidney are sought and degree of having.Wherein, Cortex Phellodendri bitter in the mouth, cold in nature, there is effect of heat clearing away, dampness, pathogenic fire purging, removing toxic substances; Radix Paeoniae sour in the mouth, micro-hardship, cold nature, has the effect of the yin fluid astringing that nourishes blood, yin nourishing suppressing the hyperactive liver and nourishing the liver hepatoprotective, has good therapeutical effect to the skin injury caused by herpes simplex infections; Propolis bitter in the mouth is pungent, cold in nature, has the effect of anti-inflammation, immunomodulating, antioxidation, acceleration organization healing, to the killing action of herpes simplex virus and herpes stomatitis virus shell; Folium Artemisiae Argyi bitter in the mouth is pungent, warm in nature, has blood of regulating the flow of vital energy, effect by cold-damp, warming the meridian, hemostasis, inhibited to adenovirus type III, rhinovirus, herpesvirus etc.; Herba Ephedrae acrid in the mouth, micro-hardship, warm in nature, there is effect of relieving the exterior syndrome by diaphoresis, depressed lung-energy dispersing, inducing diuresis to remove edema, loose crux, inhibited to virus; Radix Et Rhizoma Rhei bitter in the mouth and micro-puckery, cold in nature, has the effect of attacking stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, removing toxic substances; Rhizoma Atractylodis bitter in the mouth is pungent, warm in nature, has effect that is drying damp and strengthening spleen, wind-damp dispelling, has fire extinguishing or inhibitory action to virus; Bulbus Fritillariae Uninbracteatae sweet-bitter flavor, cold nature, has effect of relieving cough and resolving phlegm, heat clearing away eliminating stagnation; Radix Trichosanthis sweet in the mouth, micro-hardship, cold nature, has effect of clearing away heat-fire, promoting the production of body fluid to quench thirst, evacuation of pus detumescence; Radix Ginseng sweet in the mouth, micro-hardship, slightly warm in nature, has effect of invigorating vital QI, promoting the production of body fluid and inducing sedation of the mind, can reach antiviral effect by Promote immunity function; Radix Astragali sweet in the mouth, warm in nature, there is enhancing human body immunity function, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action widely, by improving body inducement interferon, virus breeding can be suppressed to a certain extent.
Drug dose of the present invention, counts by mass parts: Cortex Phellodendri 6-15 part, Radix Paeoniae 15-25 part, propolis 5-10 part, Folium Artemisiae Argyi 3-9 part, Herba Ephedrae 6-15 part, Radix Et Rhizoma Rhei 5-10 part, Rhizoma Atractylodis 6-15 part, Bulbus Fritillariae Uninbracteatae 15-25 part, Radix Trichosanthis 3-9 part, Radix Ginseng 6-15 part and Radix Astragali 5-10 part.
Be preferably Cortex Phellodendri 9 parts, Radix Paeoniae 20 parts, propolis 8 parts, Folium Artemisiae Argyi 6 parts, 10 parts, Herba Ephedrae, Radix Et Rhizoma Rhei 8 parts, Rhizoma Atractylodis 10 parts, Bulbus Fritillariae Uninbracteatae 20 parts, Radix Trichosanthis 8 parts, Radix Ginseng 10 parts and the Radix Astragali 6 parts.
The preparation of Chinese medicine composition of the present invention is powder, pill, tablet, medical herbs decoction, capsule preparations or oral liquid formulations.
The preparation method of described Chinese medicine composition composition powders, concrete steps are:
A. by described component according to proportioning mix homogeneously, be ground into 80-100 object medicated powder;
B. steps A gained medicated powder is placed in mix homogeneously in mixing and blending machine;
C. by step B gained disinfection, pack or bottling, be placed in shady and cool dry place and preserve.
The preparation method of described Chinese medicinal composition capsules preparation, concrete steps are:
A. get the Cortex Phellodendri of above-mentioned weight portion, Radix Paeoniae, Radix Et Rhizoma Rhei, Bulbus Fritillariae Uninbracteatae, Radix Trichosanthis and the Radix Astragali and obtain compositions A, get the propolis of above-mentioned weight portion, Folium Artemisiae Argyi, Herba Ephedrae, Rhizoma Atractylodis and Radix Ginseng and obtain compositions B;
B. compositions A is pulverized and sieved, obtain the powder of compositions A;
C. extract step B gained, concentration obtains extractum;
D. step C gained is placed in mixer, then mixes after adding compd B, after mix homogeneously, carry out capsule charge with capsule filler;
E. step B resulting articles is carried out polishing in capsule polisher.
In the process preparing capsule preparations, Cortex Phellodendri, Radix Paeoniae, Radix Et Rhizoma Rhei, Bulbus Fritillariae Uninbracteatae, Radix Trichosanthis and Radix Astragali pulverizer are pulverized, material after pulverizing, Cortex Phellodendri, Radix Paeoniae, Radix Trichosanthis cross the spin vibration sieve of installation 60 mesh sieve, Radix Et Rhizoma Rhei, Bulbus Fritillariae Uninbracteatae, the Radix Astragali cross the spin vibration sieve of installation 80 mesh sieve, and whole pulverizing medicinal materials is until by regulation order number sieve net.
In step C concentrated until all extracting solution are concentrated into stop when relative density is 1.20 concentrated.
Relative density is the density of extracting solution and the ratio of the density of water herein.
The present invention is based on the principle of tcm treatment according to syndrome differentiation, a kind of Chinese medicine composition for the treatment of Marek evident in efficacy, with low cost is provided.The present invention is based on the principle of tcm treatment according to syndrome differentiation, a kind of Chinese medicine composition for the treatment of Marek evident in efficacy, with low cost is provided.From the pathology of Marek, improve the yin or yang excess situation partially declined in body, the QI and blood of the spleen and stomach regulating, Liver and kidney, make it battalion and unimpeded, after trace mineral element in spice enters body, its effective ingredient of body Absorbable rod participates in body metabolism, and the balance of conditioning human body negative and positive, internal organs and QI and blood, gets rid of illness and consolidate on the whole.Chinese medicinal composition capsules preparation prepared by the application is remarkable to the therapeutic effect of common chicken Marek, and to the cure rate of common chicken Marek up to 83%, obvious effective rate (herein, to be cured and effective) up to 88.5% effective comprising.
Detailed description of the invention
Embodiment 1
Be used for the treatment of the Chinese medicine compound of Marek, composed of the following components: Cortex Phellodendri 6g, Radix Paeoniae 15g, propolis 10g, Folium Artemisiae Argyi 9g, Herba Ephedrae 6g, Radix Et Rhizoma Rhei 5g, Rhizoma Atractylodis 15g, Bulbus Fritillariae Uninbracteatae 25g, Radix Trichosanthis 3g, Radix Ginseng 15g and Radix Astragali 5g.
Prepare capsule preparations with this Chinese medicine composition, its preparation method is:
A. get the Cortex Phellodendri of above-mentioned weight portion, Radix Paeoniae, Radix Et Rhizoma Rhei, Bulbus Fritillariae Uninbracteatae, Radix Trichosanthis and the Radix Astragali and obtain compositions A, get the propolis of above-mentioned weight portion, Folium Artemisiae Argyi, Herba Ephedrae, Rhizoma Atractylodis and Radix Ginseng and obtain compositions B;
B. compositions A is pulverized and sieved, obtain the powder of compositions A;
C. extract step B gained, concentration obtains extractum;
D. step C gained is placed in mixer, then mixes after adding compd B, after mix homogeneously, carry out capsule charge with capsule filler;
E. step B resulting articles is carried out polishing in capsule polisher.
In the process preparing capsule preparations, Cortex Phellodendri, Radix Paeoniae, Radix Et Rhizoma Rhei, Bulbus Fritillariae Uninbracteatae, Radix Trichosanthis and Radix Astragali pulverizer are pulverized, material after pulverizing, Cortex Phellodendri, Radix Paeoniae, Radix Trichosanthis cross the spin vibration sieve of installation 60 mesh sieve, Radix Et Rhizoma Rhei, Bulbus Fritillariae Uninbracteatae, the Radix Astragali cross the spin vibration sieve of installation 80 mesh sieve, and whole pulverizing medicinal materials is until by regulation order number sieve net.
In step C concentrated until all extracting solution are concentrated into stop when relative density is 1.20 concentrated.
Embodiment 2
Be used for the treatment of the Chinese medicine composition of Marek, composed of the following components: Cortex Phellodendri 15g, Radix Paeoniae 25g, propolis 5g, Folium Artemisiae Argyi 3g, Herba Ephedrae 15g, Radix Et Rhizoma Rhei 5-10g, Rhizoma Atractylodis 6-15g, Bulbus Fritillariae Uninbracteatae 15-25g, Radix Trichosanthis 3-9g, Radix Ginseng 6-15g and Radix Astragali 5-10g.
Prepare capsule preparations with this Chinese medicine composition, its preparation method is:
A. get the Cortex Phellodendri of above-mentioned weight portion, Radix Paeoniae, Radix Et Rhizoma Rhei, Bulbus Fritillariae Uninbracteatae, Radix Trichosanthis and the Radix Astragali and obtain compositions A, get the propolis of above-mentioned weight portion, Folium Artemisiae Argyi, Herba Ephedrae, Rhizoma Atractylodis and Radix Ginseng and obtain compositions B;
B. compositions A is pulverized and sieved, obtain the powder of compositions A;
C. extract step B gained, concentration obtains extractum;
D. step C gained is placed in mixer, then mixes after adding compd B, after mix homogeneously, carry out capsule charge with capsule filler;
E. step B resulting articles is carried out polishing in capsule polisher.
In the process preparing capsule preparations, Cortex Phellodendri, Radix Paeoniae, Radix Et Rhizoma Rhei, Bulbus Fritillariae Uninbracteatae, Radix Trichosanthis and Radix Astragali pulverizer are pulverized, material after pulverizing, Cortex Phellodendri, Radix Paeoniae, Radix Trichosanthis cross the spin vibration sieve of installation 60 mesh sieve, Radix Et Rhizoma Rhei, Bulbus Fritillariae Uninbracteatae, the Radix Astragali cross the spin vibration sieve of installation 80 mesh sieve, and whole pulverizing medicinal materials is until by regulation order number sieve net.
In step C concentrated until all extracting solution are concentrated into stop when relative density is 1.20 concentrated.
Embodiment 3
Be used for the treatment of the Chinese medicine composition of Marek, composed of the following components: Cortex Phellodendri 9g, Radix Paeoniae 20g, propolis 8g, Folium Artemisiae Argyi 6g, Herba Ephedrae 10g, Radix Et Rhizoma Rhei 8g, Rhizoma Atractylodis 10g, Bulbus Fritillariae Uninbracteatae 20g, Radix Trichosanthis 8g, Radix Ginseng 10g and Radix Astragali 6g.
Prepare capsule preparations with this Chinese medicine composition, its preparation method is:
A. get the Cortex Phellodendri of above-mentioned weight portion, Radix Paeoniae, Radix Et Rhizoma Rhei, Bulbus Fritillariae Uninbracteatae, Radix Trichosanthis and the Radix Astragali and obtain compositions A, get the propolis of above-mentioned weight portion, Folium Artemisiae Argyi, Herba Ephedrae, Rhizoma Atractylodis and Radix Ginseng and obtain compositions B;
B. compositions A is pulverized and sieved, obtain the powder of compositions A;
C. extract step B gained, concentration obtains extractum;
D. step C gained is placed in mixer, then mixes after adding compd B, after mix homogeneously, carry out capsule charge with capsule filler;
E. step B resulting articles is carried out polishing in capsule polisher.
In the process preparing capsule preparations, Cortex Phellodendri, Radix Paeoniae, Radix Et Rhizoma Rhei, Bulbus Fritillariae Uninbracteatae, Radix Trichosanthis and Radix Astragali pulverizer are pulverized, material after pulverizing, Cortex Phellodendri, Radix Paeoniae, Radix Trichosanthis cross the spin vibration sieve of installation 60 mesh sieve, Radix Et Rhizoma Rhei, Bulbus Fritillariae Uninbracteatae, the Radix Astragali cross the spin vibration sieve of installation 80 mesh sieve, and whole pulverizing medicinal materials is until by regulation order number sieve net.
In step C concentrated until all extracting solution are concentrated into stop when relative density is 1.20 concentrated.
Embodiment 4
Suffers from the common chicken 47 of Marek.Capsule preparations prepared by embodiment 3 is fed each once to ill common chicken morning and evening every day, take three altogether.Take period without other drug; Evaluation effect standard: cure, use rear symptom substantially to disappear; Effectively, use rear symptom to alleviate, but do not take a turn for the better completely; Invalid, use rear without positive effect.Use after 3 days, healing is 39, is effectively 4, and invalid is 4.
From above result, the therapeutic effect of Chinese medicinal composition capsules preparation to common chicken Marek prepared by the application is remarkable, to the cure rate of common chicken Marek up to 83%, to the obvious effective rate of common chicken Marek up to 88.5% (herein, effective comprise recovery from illness and effectively).
What finally illustrate is, above embodiment is only in order to illustrate technical scheme of the present invention and unrestricted, those of ordinary skill in the art is to be understood that, can modify to technical scheme or equivalent replacement, and not departing from aim and the scope of technical solution of the present invention, it all should be encompassed in the middle of right of the present invention.
Claims (7)
1. be used for the treatment of the Chinese medicine composition of Marek, it is characterized in that, be made up of the former medicine of following mass parts: Cortex Phellodendri 6-15 part, Radix Paeoniae 15-25 part, propolis 5-10 part, Folium Artemisiae Argyi 3-9 part, Herba Ephedrae 6-15 part, Radix Et Rhizoma Rhei 5-10 part, Rhizoma Atractylodis 6-15 part, Bulbus Fritillariae Uninbracteatae 15-25 part, Radix Trichosanthis 3-9 part, Radix Ginseng 6-15 part and Radix Astragali 5-10 part.
2. Chinese medicine composition according to claim 1, it is characterized in that, be made up of the former medicine of following mass parts: Cortex Phellodendri 9 parts, Radix Paeoniae 20 parts, propolis 8 parts, Folium Artemisiae Argyi 6 parts, 10 parts, Herba Ephedrae, Radix Et Rhizoma Rhei 8 parts, Rhizoma Atractylodis 10 parts, Bulbus Fritillariae Uninbracteatae 20 parts, Radix Trichosanthis 8 parts, Radix Ginseng 10 parts and the Radix Astragali 6 parts.
3. the preparation of the Chinese medicine composition described in claim 1 or 2, is characterized in that: the preparation of described Chinese medicine composition is powder, pill, tablet, medical herbs decoction, capsule preparations or oral liquid formulations.
4. the preparation of Chinese medicine composition according to claim 3, is characterized in that, the preparation method of described Chinese medicine composition composition powders, and concrete steps are:
A. by said components according to proportioning mix homogeneously, be ground into 80-100 object medicated powder;
B. steps A gained medicated powder is placed in mix homogeneously in mixing and blending machine;
C. by step B gained disinfection, pack or bottling, be placed in shady and cool dry place and preserve.
5. the preparation of Chinese medicine composition according to claim 4, is characterized in that, the preparation method of described Chinese medicinal composition capsules preparation, and concrete steps are:
A. get the Cortex Phellodendri of above-mentioned weight portion, Radix Paeoniae, Radix Et Rhizoma Rhei, Bulbus Fritillariae Uninbracteatae, Radix Trichosanthis and the Radix Astragali and obtain compositions A, get the propolis of above-mentioned weight portion, Folium Artemisiae Argyi, Herba Ephedrae, Rhizoma Atractylodis and Radix Ginseng and obtain compositions B;
B. compositions A is pulverized and sieved, obtain the powder of compositions A;
C. extract step B gained, concentration obtains extractum;
D. step C gained is placed in mixer, then mixes after adding compd B, after mix homogeneously, carry out capsule charge with capsule filler;
E. step B resulting articles is carried out polishing in capsule polisher.
6. the preparation of Chinese medicine composition according to claim 5, it is characterized in that: Cortex Phellodendri, Radix Paeoniae, Radix Et Rhizoma Rhei, Bulbus Fritillariae Uninbracteatae, Radix Trichosanthis and Radix Astragali pulverizer are pulverized, material after pulverizing, Cortex Phellodendri, Radix Paeoniae, Radix Trichosanthis cross the spin vibration sieve of installation 60 mesh sieve, Radix Et Rhizoma Rhei, Bulbus Fritillariae Uninbracteatae, the Radix Astragali cross the spin vibration sieve of installation 80 mesh sieve, and whole pulverizing medicinal materials is until by regulation order number sieve net.
7. the preparation of Chinese medicine composition according to claim 5, is characterized in that: in step C concentrated until all extracting solution are concentrated into stop when relative density is 1.20 concentrated.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106615793A (en) * | 2016-12-14 | 2017-05-10 | 巫溪县长贵养殖有限公司 | Wild boar Chinese herbal medicine feed additive as well as preparation method and application thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102397510A (en) * | 2011-11-15 | 2012-04-04 | 青岛绿曼生物工程有限公司 | Compound propolis composition for treating chicken Marek's disease and preparation method thereof |
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- 2015-11-09 CN CN201510755602.2A patent/CN105395810A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102397510A (en) * | 2011-11-15 | 2012-04-04 | 青岛绿曼生物工程有限公司 | Compound propolis composition for treating chicken Marek's disease and preparation method thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106615793A (en) * | 2016-12-14 | 2017-05-10 | 巫溪县长贵养殖有限公司 | Wild boar Chinese herbal medicine feed additive as well as preparation method and application thereof |
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Application publication date: 20160316 |