CN101855338B - 在程序重排体细胞中的wnt途径刺激 - Google Patents
在程序重排体细胞中的wnt途径刺激 Download PDFInfo
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- CN101855338B CN101855338B CN2008801129864A CN200880112986A CN101855338B CN 101855338 B CN101855338 B CN 101855338B CN 2008801129864 A CN2008801129864 A CN 2008801129864A CN 200880112986 A CN200880112986 A CN 200880112986A CN 101855338 B CN101855338 B CN 101855338B
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- C12N2501/603—Oct-3/4
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- C12N2501/604—Klf-4
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96702807P | 2007-08-31 | 2007-08-31 | |
| US60/967,028 | 2007-08-31 | ||
| US18819008P | 2008-08-06 | 2008-08-06 | |
| US61/188,190 | 2008-08-06 | ||
| PCT/US2008/010249 WO2009032194A1 (en) | 2007-08-31 | 2008-08-29 | Wnt pathway stimulation in reprogramming somatic cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101855338A CN101855338A (zh) | 2010-10-06 |
| CN101855338B true CN101855338B (zh) | 2013-07-17 |
Family
ID=40429192
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2008801129864A Active CN101855338B (zh) | 2007-08-31 | 2008-08-29 | 在程序重排体细胞中的wnt途径刺激 |
Country Status (10)
| Country | Link |
|---|---|
| US (6) | US9102919B2 (enExample) |
| EP (2) | EP3078738B1 (enExample) |
| JP (8) | JP6151879B2 (enExample) |
| CN (1) | CN101855338B (enExample) |
| AU (5) | AU2008297011B2 (enExample) |
| CA (2) | CA2698091C (enExample) |
| ES (2) | ES2589122T3 (enExample) |
| MX (1) | MX2010002242A (enExample) |
| RU (1) | RU2492232C2 (enExample) |
| WO (1) | WO2009032194A1 (enExample) |
Families Citing this family (110)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7682828B2 (en) | 2003-11-26 | 2010-03-23 | Whitehead Institute For Biomedical Research | Methods for reprogramming somatic cells |
| US20090227032A1 (en) | 2005-12-13 | 2009-09-10 | Kyoto University | Nuclear reprogramming factor and induced pluripotent stem cells |
| US8129187B2 (en) | 2005-12-13 | 2012-03-06 | Kyoto University | Somatic cell reprogramming by retroviral vectors encoding Oct3/4. Klf4, c-Myc and Sox2 |
| US8278104B2 (en) | 2005-12-13 | 2012-10-02 | Kyoto University | Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2 |
| KR101420740B1 (ko) | 2005-12-13 | 2014-07-17 | 교또 다이가꾸 | 핵초기화 인자 |
| EP2137296A2 (en) | 2007-03-23 | 2009-12-30 | Wisconsin Alumni Research Foundation | Somatic cell reprogramming |
| CN105861443A (zh) * | 2007-04-07 | 2016-08-17 | 怀特黑德生物医学研究所 | 体细胞重编程 |
| US9213999B2 (en) | 2007-06-15 | 2015-12-15 | Kyoto University | Providing iPSCs to a customer |
| JP2008307007A (ja) * | 2007-06-15 | 2008-12-25 | Bayer Schering Pharma Ag | 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞 |
| EP3078738B1 (en) | 2007-08-31 | 2020-05-20 | Whitehead Institute for Biomedical Research | Wnt pathway stimulation in reprogramming somatic cells |
| EP2090649A1 (en) * | 2008-02-13 | 2009-08-19 | Fondazione Telethon | Method for reprogramming differentiated cells |
| WO2009102983A2 (en) * | 2008-02-15 | 2009-08-20 | President And Fellows Of Harvard College | Efficient induction of pluripotent stem cells using small molecule compounds |
| ES2690554T3 (es) * | 2008-03-17 | 2018-11-21 | The Scripps Research Institute | Enfoques químicos y genéticos combinados para la generación de células madre pluripotentes inducidas |
| ES2722198T3 (es) | 2008-05-02 | 2019-08-08 | Univ Kyoto | Método de reprogramación nuclear |
| EP3447128A1 (en) | 2008-06-04 | 2019-02-27 | FUJIFILM Cellular Dynamics, Inc. | Methods for the production of ips cells using non-viral approach |
| CN105671065A (zh) * | 2008-06-13 | 2016-06-15 | 怀特黑德生物医学研究所 | 细胞编程和重编程 |
| CN102171348A (zh) | 2008-08-12 | 2011-08-31 | 细胞动力国际有限公司 | 产生ips细胞的方法 |
| EP2376626A4 (en) * | 2008-12-13 | 2012-10-17 | Dna Microarray | MICRO-ENVIRONMENTAL NICHE ASSAY FOR SCREENING OF INDUCED PLURIPOTENT STEM CELLS (CIPS) |
| ES2645869T3 (es) | 2008-12-17 | 2017-12-11 | The Scripps Research Institute | Generación y mantenimiento de células madre |
| ES2664590T3 (es) * | 2009-05-18 | 2018-04-20 | Curna, Inc. | Tratamiento de enfermedades relacionadas con factores de reprogramación por inhibición del tránscrito antisentido natural a un factor de reprogramación |
| CN103087991B (zh) * | 2009-06-05 | 2018-06-12 | 富士胶片细胞动力公司 | 重编程t细胞和造血细胞的方法 |
| JP2011004674A (ja) * | 2009-06-26 | 2011-01-13 | Fujitsu Ltd | 誘導多能性幹細胞(iPS細胞)の製造方法 |
| US9175265B2 (en) | 2009-07-08 | 2015-11-03 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Method for inducing extended self-renewal of functionally differentiated somatic cells |
| EP2451982B1 (en) | 2009-07-09 | 2014-11-12 | Whitehead Institute For Biomedical Research | Compositions and methods for mammalian genetics and uses thereof |
| JP5751548B2 (ja) * | 2009-08-07 | 2015-07-22 | 国立大学法人京都大学 | イヌiPS細胞及びその製造方法 |
| ES2638464T3 (es) | 2009-10-16 | 2017-10-20 | The Scripps Research Institute | Inducción de células pluripotentes |
| US9453205B2 (en) | 2009-10-31 | 2016-09-27 | Genesis Technologies Limited | Methods for reprogramming cells and uses thereof |
| AU2010312240B2 (en) * | 2009-10-31 | 2016-12-15 | Genesis Technologies Limited | Methods for reprogramming cells and uses thereof |
| US20140038291A1 (en) | 2009-10-31 | 2014-02-06 | New World Laboratories Inc. | Methods for reprogramming cells and uses thereof |
| ES2539487T3 (es) * | 2009-11-04 | 2015-07-01 | Cellular Dynamics International, Inc. | Reprogramación episómica con compuestos químicos |
| EP2499237A1 (en) * | 2009-11-13 | 2012-09-19 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Reprogrammation of eukaryotic cells with engineered microvesicles |
| AU2011235212B2 (en) | 2010-03-31 | 2014-07-31 | The Scripps Research Institute | Reprogramming cells |
| EP3399026B1 (en) | 2010-06-14 | 2024-06-26 | The Scripps Research Institute | Reprogramming of cells to a new fate |
| JPWO2011158852A1 (ja) * | 2010-06-15 | 2013-08-19 | 国立大学法人 東京大学 | 誘導型多能性幹細胞の製造方法 |
| CN106893692B (zh) | 2010-12-22 | 2021-11-26 | 菲特治疗公司 | 用于单细胞分选与增强ipsc重新编程的细胞培养平台 |
| ES2575605T3 (es) * | 2010-12-31 | 2016-06-29 | Universität Für Bodenkultur Wien | Método de generación de células madre pluripotentes inducidas y células diferenciadas |
| CN107988381B (zh) | 2011-07-25 | 2021-05-28 | 国立大学法人京都大学 | 筛选诱导的多能干细胞的方法 |
| JP6208667B2 (ja) * | 2011-10-03 | 2017-10-04 | ユニベルシテ リブレ デ ブリュッセル | 持続的hiv感染症を処置するためのhiv−1遺伝子発現の再活性化 |
| JP6162604B2 (ja) | 2011-10-21 | 2017-07-12 | 国立大学法人京都大学 | 層流による多能性維持単一分散細胞培養法 |
| WO2013077423A1 (ja) | 2011-11-25 | 2013-05-30 | 国立大学法人京都大学 | 多能性幹細胞の培養方法 |
| RU2477314C1 (ru) * | 2011-12-07 | 2013-03-10 | Федеральное государственное бюджетное учреждение "Новосибирский научно-исследовательский институт патологии кровообращения имени академика Е.Н. Мешалкина" Минздравсоцразвития РФ, (ФГБУ "ННИИПК им. акад. Е.Н. Мешалкина" Минздравсоцразвития России) | РЕКОМБИНАНТНАЯ ПЛАЗМИДА pSM-ZsGreen, КОДИРУЮЩАЯ БЕЛКИ SOX2 И С-MYC ЧЕЛОВЕКА И ФЛУОРЕСЦЕНТНЫЙ БЕЛОК ZsGreen, ПРЕДНАЗНАЧЕННАЯ ДЛЯ ПОЛУЧЕНИЯ ИНДУЦИРОВАННЫХ ПЛЮРИПОТЕНТНЫХ СТВОЛОВЫХ КЛЕТОК ЧЕЛОВЕКА |
| WO2013159103A1 (en) * | 2012-04-20 | 2013-10-24 | Whitehead Institute For Biomedical Research | Programming and reprogramming of cells |
| SG11201503167XA (en) * | 2012-10-23 | 2015-05-28 | Univ Kyoto | Method of efficiently establishing induced pluripotent stem cells |
| JP6495658B2 (ja) | 2013-02-08 | 2019-04-03 | 国立大学法人京都大学 | 巨核球及び血小板の製造方法 |
| WO2014136581A1 (ja) | 2013-03-06 | 2014-09-12 | 国立大学法人京都大学 | 多能性幹細胞の培養システム及び多能性幹細胞の継代方法 |
| HK1220232A1 (zh) | 2013-03-15 | 2017-04-28 | 怀特黑德生物医学研究院 | 用於神经变性疾病的细胞性发现平台 |
| EP2977449B1 (en) | 2013-03-21 | 2020-02-26 | Kyoto University | Pluripotent stem cell for neuronal differentiation induction |
| WO2014157257A1 (ja) | 2013-03-25 | 2014-10-02 | 公益財団法人先端医療振興財団 | 細胞の選別方法 |
| JP6461787B2 (ja) | 2013-04-12 | 2019-01-30 | 国立大学法人京都大学 | 肺胞上皮前駆細胞の誘導方法 |
| JP6429280B2 (ja) | 2013-05-14 | 2018-11-28 | 国立大学法人京都大学 | 効率的な心筋細胞の誘導方法 |
| CN105247041B (zh) | 2013-05-31 | 2018-04-20 | 爱心细胞有限公司 | 组入有水凝胶的层叠细胞膜片 |
| EP3020803B1 (en) | 2013-06-11 | 2020-03-11 | Kyoto University | Method for producing renal precursor cells |
| US9796962B2 (en) | 2013-08-07 | 2017-10-24 | Kyoto University | Method for generating pancreatic hormone-producing cells |
| SG11201601720RA (en) | 2013-09-05 | 2016-04-28 | Univ Kyoto | New method for inducing dopamine-producing neural precursor cells |
| JP6635505B2 (ja) | 2013-11-01 | 2020-01-29 | 国立大学法人京都大学 | 新規軟骨細胞誘導方法 |
| SG10201807292YA (en) | 2014-03-04 | 2018-09-27 | Fate Therapeutics Inc | Improved reprogramming methods and cell culture platforms |
| US11066649B2 (en) | 2014-03-19 | 2021-07-20 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Method for inducing human cholangiocyte differentiation |
| EP3929302A1 (en) | 2014-07-14 | 2021-12-29 | Chugai Seiyaku Kabushiki Kaisha | Method for identifying epitope on protein |
| US12241089B2 (en) | 2014-07-18 | 2025-03-04 | Kyoto University | Method for inducing t cells for cell-based immunotherapy from pluripotent stem cells |
| US11261453B2 (en) | 2014-09-12 | 2022-03-01 | Whitehead Institute For Biomedical Research | Cells expressing apolipoprotein E and uses thereof |
| WO2016104717A1 (ja) | 2014-12-26 | 2016-06-30 | 国立大学法人京都大学 | 肝細胞誘導方法 |
| JP2018504122A (ja) | 2015-01-26 | 2018-02-15 | フェイト セラピューティクス,インコーポレイテッド | 免疫調節特性が増加した細胞ならびにその使用および製造のための方法 |
| HK1248270A1 (zh) | 2015-02-17 | 2018-10-12 | 大学健康网路 | 制备和使用窦房结样起搏器心肌细胞和心室样心肌细胞的方法 |
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