CN101541979B - 同时检测和鉴别眼睛和中枢神经系统的细菌、真菌、寄生虫和病毒感染的方法 - Google Patents

同时检测和鉴别眼睛和中枢神经系统的细菌、真菌、寄生虫和病毒感染的方法 Download PDF

Info

Publication number
CN101541979B
CN101541979B CN200880000035.8A CN200880000035A CN101541979B CN 101541979 B CN101541979 B CN 101541979B CN 200880000035 A CN200880000035 A CN 200880000035A CN 101541979 B CN101541979 B CN 101541979B
Authority
CN
China
Prior art keywords
seq
dna
group
combination
primer sets
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN200880000035.8A
Other languages
English (en)
Chinese (zh)
Other versions
CN101541979A (zh
Inventor
C·M·拉奥
K·S·拉奥
P·V·拉姆钱德
H·N·玛德哈范
S·沙玛
G·萨特帕泰
V·B·拉维库玛
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Council of Scientific and Industrial Research CSIR
Original Assignee
Council of Scientific and Industrial Research CSIR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Council of Scientific and Industrial Research CSIR filed Critical Council of Scientific and Industrial Research CSIR
Priority to CN201410521073.5A priority Critical patent/CN104313180B/zh
Publication of CN101541979A publication Critical patent/CN101541979A/zh
Application granted granted Critical
Publication of CN101541979B publication Critical patent/CN101541979B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/6895—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/705—Specific hybridization probes for herpetoviridae, e.g. herpes simplex, varicella zoster
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2527/00—Reactions demanding special reaction conditions
    • C12Q2527/101—Temperature
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
    • C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/143—Multiplexing, i.e. use of multiple primers or probes in a single reaction, usually for simultaneously analyse of multiple analysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2561/00—Nucleic acid detection characterised by assay method
    • C12Q2561/113—Real time assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN200880000035.8A 2007-06-01 2008-05-27 同时检测和鉴别眼睛和中枢神经系统的细菌、真菌、寄生虫和病毒感染的方法 Expired - Fee Related CN101541979B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201410521073.5A CN104313180B (zh) 2007-06-01 2008-05-27 同时检测和鉴别眼睛和中枢神经系统的细菌、真菌、寄生虫和病毒感染的新方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN1178DE2007 2007-06-01
IN1178/DEL/2007 2007-06-01
PCT/IN2008/000334 WO2008146306A2 (en) 2007-06-01 2008-05-27 A novel method for simultaneous detection and discrimination of bacterial, fungal, parasitic and viral infections of eye and central nervous system

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201410521073.5A Division CN104313180B (zh) 2007-06-01 2008-05-27 同时检测和鉴别眼睛和中枢神经系统的细菌、真菌、寄生虫和病毒感染的新方法

Publications (2)

Publication Number Publication Date
CN101541979A CN101541979A (zh) 2009-09-23
CN101541979B true CN101541979B (zh) 2014-11-05

Family

ID=39831681

Family Applications (2)

Application Number Title Priority Date Filing Date
CN200880000035.8A Expired - Fee Related CN101541979B (zh) 2007-06-01 2008-05-27 同时检测和鉴别眼睛和中枢神经系统的细菌、真菌、寄生虫和病毒感染的方法
CN201410521073.5A Expired - Fee Related CN104313180B (zh) 2007-06-01 2008-05-27 同时检测和鉴别眼睛和中枢神经系统的细菌、真菌、寄生虫和病毒感染的新方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201410521073.5A Expired - Fee Related CN104313180B (zh) 2007-06-01 2008-05-27 同时检测和鉴别眼睛和中枢神经系统的细菌、真菌、寄生虫和病毒感染的新方法

Country Status (14)

Country Link
US (3) US8465951B2 (enExample)
EP (1) EP2155909B1 (enExample)
JP (2) JP5718049B2 (enExample)
KR (1) KR101866766B1 (enExample)
CN (2) CN101541979B (enExample)
AR (2) AR066825A1 (enExample)
AU (1) AU2008256216B2 (enExample)
BR (1) BRPI0812178A2 (enExample)
CA (1) CA2689306C (enExample)
IL (1) IL202459A (enExample)
MY (2) MY163053A (enExample)
NZ (1) NZ582232A (enExample)
TW (1) TWI410491B (enExample)
WO (1) WO2008146306A2 (enExample)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2661474B1 (fr) 1990-04-25 1992-06-12 Valeo Double volant amortisseur de torsion pour moteur a combustion interne.
JP2788853B2 (ja) 1994-02-14 1998-08-20 株式会社エクセディ ダンパー装置
EP2155909B1 (en) * 2007-06-01 2018-03-07 Council Of Scientific & Industrial Research Method for simultaneous detection and discrimination of bacterial, fungal, parasitic and viral infections of eye and central nervous system
WO2010130877A2 (en) * 2009-05-12 2010-11-18 Abacus Diagnostica Oy Method for detecting nucleic acids
EP2270202A1 (en) * 2009-07-03 2011-01-05 John Ikonomopoulos Mycobacterial detection
IN2014MN01780A (enExample) 2012-02-09 2015-07-03 Memed Diagnostics Ltd
US20130302784A1 (en) * 2012-03-30 2013-11-14 Intelligent Medical Devices, Inc. Optimized probes and primers and methods of using same for the binding, detection, differentiation, isolation and sequencing of herpes simplex virus
CN103045761B (zh) * 2012-12-14 2016-01-20 山东省眼科研究所 用于检测感染性眼病致病微生物的试剂盒及检测方法
WO2014186874A1 (en) 2013-05-23 2014-11-27 Yyz Pharmatech, Inc. Methods and compositions for enzyme linked immuno and hybridization mass spectrometric assay
CA2954601C (en) 2014-08-14 2023-04-18 Memed Diagnostics Ltd. Computational analysis of biological data using manifold and a hyperplane
CN204050005U (zh) * 2014-09-09 2014-12-31 赵潺 一次性负压前房穿刺针
US20170234873A1 (en) 2014-10-14 2017-08-17 Memed Diagnostics Ltd. Signatures and determinants for diagnosing infections in non-human subjects and methods of use thereof
WO2016073237A1 (en) 2014-11-05 2016-05-12 Illumina Cambridge Limited Reducing dna damage during sample preparation and sequencing using siderophore chelators
JP6723924B2 (ja) * 2014-11-19 2020-07-15 大塚製薬株式会社 Ｐｋｄ１遺伝子及びｐｋｄ２遺伝子のエクソンを増幅するためのプライマーセット及び方法
US20170269081A1 (en) 2014-12-11 2017-09-21 Memed Diagnostics Ltd. Marker combinations for diagnosing infections and methods of use thereof
KR101521409B1 (ko) * 2015-01-15 2015-05-18 경북대학교 산학협력단 진균성 및 아메바성 각막염의 원인체를 동시에 검출할 수 있는 다중 중합효소 연쇄반응 프라이머 세트 및 이를 이용한 각막염 유발균 검출 방법
WO2016184987A1 (en) * 2015-05-19 2016-11-24 Yaya Diagnostics Gmbh Means and methods for the enrichment of nucleic acids
IL294121B2 (en) 2016-03-03 2023-09-01 Memed Diagnostics Ltd An RNA test to diagnose the type of infection
WO2017149548A1 (en) 2016-03-03 2017-09-08 Memed Diagnostics Ltd. Rna determinants for distinguishing between bacterial and viral infections
CN106167833B (zh) * 2016-05-20 2019-09-20 南方医科大学 一种同时检测8种虫媒脑炎病毒的rt-pcr引物和探针组合及试剂盒
WO2018011795A1 (en) 2016-07-10 2018-01-18 Memed Diagnostics Ltd. Protein signatures for distinguishing between bacterial and viral infections
US11340223B2 (en) 2016-07-10 2022-05-24 Memed Diagnostics Ltd. Early diagnosis of infections
US11385241B2 (en) 2016-09-29 2022-07-12 Memed Diagnostics Ltd. Methods of prognosis and treatment
CN110073220A (zh) 2016-09-29 2019-07-30 米密德诊断学有限公司 风险评估和疾病分类的方法
CN106834548B (zh) * 2017-03-30 2020-03-27 广州基迪奥生物科技有限公司 一种常见眼内感染病毒多重实时荧光pcr检测试剂盒
US10209260B2 (en) 2017-07-05 2019-02-19 Memed Diagnostics Ltd. Signatures and determinants for diagnosing infections and methods of use thereof
US12195810B2 (en) 2017-12-22 2025-01-14 Massachusetts Eye And Ear Infirmary Comprehensive microbial panel for molecular diagnosis of eye infections
KR102297545B1 (ko) * 2020-02-06 2021-09-02 경희대학교 산학협력단 코리스메이트 뮤테이즈 단백질 항체를 포함하는 가시아메바성 각막염의 감별 진단용 조성물 및 이를 이용한 가시아메바성 각막염 진단 키트
CN111763767A (zh) * 2020-06-04 2020-10-13 上海捷诺生物科技有限公司 中枢神经系统感染病原体检测试剂盒及其应用
CN113201599B (zh) * 2021-06-03 2023-03-31 北京大学人民医院 一种基于PCR和nanopore测序检测脑脊液感染哪些病原体的方法
CN114277167A (zh) * 2021-12-31 2022-04-05 杭州千基生物科技有限公司 一种用于细菌性肠道病原体的量子点核酸检测的试剂盒
CN114891870A (zh) * 2022-06-26 2022-08-12 杭州奥明医学检验实验室有限公司 一种基于mNGS检测致癌病原体的方法、系统及装置
CN116144811B (zh) * 2022-12-21 2024-02-20 迪飞医学科技(南京)有限公司 用于检测脑脊液病原的多重引物组、方法和试剂盒
CN116121428A (zh) * 2023-03-17 2023-05-16 郑州安图生物工程股份有限公司 引物探针组合及试剂盒

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1450171A (zh) * 2003-05-09 2003-10-22 陶开华 一种检测多种传染病的检测型基因芯片及应用
CN1473940A (zh) * 2002-08-09 2004-02-11 中国人民解放军基因工程研究所 一种限制性荧光标记方法
CN1508264A (zh) * 2002-12-18 2004-06-30 云南大学 一种临床感染性疾病基因芯片诊断方案
CN1896284A (zh) * 2006-06-30 2007-01-17 博奥生物有限公司 一种鉴别等位基因类型的方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639871A (en) 1988-09-09 1997-06-17 Roche Molecular Systems, Inc. Detection of human papillomavirus by the polymerase chain reaction
JPH10323189A (ja) * 1997-05-23 1998-12-08 Toyobo Co Ltd 抗酸菌属細菌の検出または菌種同定用オリゴヌクレオチドおよびその用途
US6514694B2 (en) 1997-12-19 2003-02-04 Heska Corporation Methods for the detection of encysted parasites
KR100316094B1 (ko) 1999-05-29 2001-12-20 김정준 마이코박테리아 균종 동정용 올리고뉴클레오티드
US20030027135A1 (en) 2001-03-02 2003-02-06 Ecker David J. Method for rapid detection and identification of bioagents
US20040121311A1 (en) 2002-12-06 2004-06-24 Ecker David J. Methods for rapid detection and identification of bioagents in livestock
JP2003144153A (ja) 2001-11-09 2003-05-20 Gifu Univ 遺伝子検出方法、遺伝子検出用プライマー、ｄｎａマイクロアレイ及び遺伝子検出用キット
DE602004032125D1 (de) 2003-05-07 2011-05-19 Coris Bioconcept Sprl Einstufige oligochromatographische vorrichtung und verfahren zu ihrer verwendung
CN105087777A (zh) * 2004-04-07 2015-11-25 安克塞斯生物公司 核酸检测系统
JP2006129810A (ja) * 2004-11-08 2006-05-25 Canon Inc 感染症起炎菌検出用プローブセット及び担体及び遺伝子検査方法
BRPI0607194B8 (pt) 2005-01-31 2021-07-27 Yakult Honsha Kk método e kit para analisar quantitativamente um microrganismo por marcação de rrna
CN101351559A (zh) * 2005-11-09 2009-01-21 普里梅拉生物系统有限公司 病原体的多元定量检测
CN1995387B (zh) * 2006-11-07 2010-06-23 亚能生物技术（深圳）有限公司 分枝杆菌菌种鉴定基因芯片检测系统
EP2155909B1 (en) * 2007-06-01 2018-03-07 Council Of Scientific & Industrial Research Method for simultaneous detection and discrimination of bacterial, fungal, parasitic and viral infections of eye and central nervous system

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1473940A (zh) * 2002-08-09 2004-02-11 中国人民解放军基因工程研究所 一种限制性荧光标记方法
CN1508264A (zh) * 2002-12-18 2004-06-30 云南大学 一种临床感染性疾病基因芯片诊断方案
CN1450171A (zh) * 2003-05-09 2003-10-22 陶开华 一种检测多种传染病的检测型基因芯片及应用
CN1896284A (zh) * 2006-06-30 2007-01-17 博奥生物有限公司 一种鉴别等位基因类型的方法

Also Published As

Publication number Publication date
US20130310279A1 (en) 2013-11-21
US10584392B2 (en) 2020-03-10
TWI410491B (zh) 2013-10-01
CA2689306C (en) 2019-01-15
AR066825A1 (es) 2009-09-16
JP5927243B2 (ja) 2016-06-01
CA2689306A1 (en) 2008-12-04
EP2155909A2 (en) 2010-02-24
US20170275710A1 (en) 2017-09-28
AU2008256216A1 (en) 2008-12-04
JP5718049B2 (ja) 2015-05-13
KR101866766B1 (ko) 2018-06-18
TW200907057A (en) 2009-02-16
IL202459A0 (en) 2011-08-01
NZ582232A (en) 2012-05-25
IL202459A (en) 2014-09-30
KR20100044736A (ko) 2010-04-30
MY150954A (en) 2014-03-31
MY163053A (en) 2017-08-15
BRPI0812178A2 (pt) 2021-05-04
US8465951B2 (en) 2013-06-18
AU2008256216B2 (en) 2014-07-31
CN101541979A (zh) 2009-09-23
US20110111969A1 (en) 2011-05-12
US9777339B2 (en) 2017-10-03
HK1206396A1 (en) 2016-01-08
CN104313180B (zh) 2017-05-24
AR110776A2 (es) 2019-05-02
CN104313180A (zh) 2015-01-28
EP2155909B1 (en) 2018-03-07
JP2010528599A (ja) 2010-08-26
JP2014223077A (ja) 2014-12-04
WO2008146306A3 (en) 2009-01-15
WO2008146306A2 (en) 2008-12-04

Similar Documents

Publication Publication Date Title
CN101541979B (zh) 同时检测和鉴别眼睛和中枢神经系统的细菌、真菌、寄生虫和病毒感染的方法
EP1973925A1 (en) Dna chip for diagnosis of corneal dystrophy
AU2001256976A1 (en) Detection and typing of human papillomavirus using pna probes
CN101374850A (zh) 用于角膜营养不良诊断的dna芯片
CN101379196B (zh) 用于鉴定临床样品中的人乳头瘤病毒的体外诊断试剂盒
US20090258342A1 (en) Optimized probes and primers and methods of using same for the detection, quantification and grouping of hiv-1
US20030143529A1 (en) Detection and typing of human papillomavirus using PNA probes
JP2010515451A (ja) 大腸菌検出用ｄｎａチップ
KR101623489B1 (ko) 성인성 질환의 원인균 탐지용 고감도 프로브 및 이를 포함하는 키트
KR100819634B1 (ko) 성 전파 질환 검사를 위한 신규한 올리고뉴클레오티드프로브와 이를 이용한 성 전파 질환 검사용 ｄｎａ칩,분석키트 및 그 제조 방법
HK1133282A (en) A novel method for simultaneous detection and discrimination of bacterial, fungal, parasitic and viral infections of eye and central nervous system
JP2010515452A (ja) スタフィロコッカス・アウレウス検出用ｄｎａチップ
HK1206396B (en) A novel method for simultaneous detection and discrimination of bacterial, fungal, parasitic and viral infections of eye and central nervous system
JP2009538125A (ja) Ｍｇ２１９遺伝子に基づくマイコプラズマ・ジェニタリウムの検出アッセイ

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 1133282

Country of ref document: HK

C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
REG Reference to a national code

Ref country code: HK

Ref legal event code: WD

Ref document number: 1133282

Country of ref document: HK

CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20141105