CN101541979B - 同时检测和鉴别眼睛和中枢神经系统的细菌、真菌、寄生虫和病毒感染的方法 - Google Patents

同时检测和鉴别眼睛和中枢神经系统的细菌、真菌、寄生虫和病毒感染的方法 Download PDF

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CN101541979B
CN101541979B CN200880000035.8A CN200880000035A CN101541979B CN 101541979 B CN101541979 B CN 101541979B CN 200880000035 A CN200880000035 A CN 200880000035A CN 101541979 B CN101541979 B CN 101541979B
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dna
group
combination
primer sets
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CN101541979A (zh
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C·M·拉奥
K·S·拉奥
P·V·拉姆钱德
H·N·玛德哈范
S·沙玛
G·萨特帕泰
V·B·拉维库玛
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Council of Scientific and Industrial Research CSIR
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    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
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    • C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
    • C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/143—Multiplexing, i.e. use of multiple primers or probes in a single reaction, usually for simultaneously analyse of multiple analysis
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

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CN200880000035.8A 2007-06-01 2008-05-27 同时检测和鉴别眼睛和中枢神经系统的细菌、真菌、寄生虫和病毒感染的方法 Expired - Fee Related CN101541979B (zh)

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CN201410521073.5A CN104313180B (zh) 2007-06-01 2008-05-27 同时检测和鉴别眼睛和中枢神经系统的细菌、真菌、寄生虫和病毒感染的新方法

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IN1178/DEL/2007 2007-06-01
IN1178DE2007 2007-06-01
PCT/IN2008/000334 WO2008146306A2 (en) 2007-06-01 2008-05-27 A novel method for simultaneous detection and discrimination of bacterial, fungal, parasitic and viral infections of eye and central nervous system

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CN201410521073.5A Expired - Fee Related CN104313180B (zh) 2007-06-01 2008-05-27 同时检测和鉴别眼睛和中枢神经系统的细菌、真菌、寄生虫和病毒感染的新方法

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EP (1) EP2155909B1 (enExample)
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Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2661474B1 (fr) 1990-04-25 1992-06-12 Valeo Double volant amortisseur de torsion pour moteur a combustion interne.
JP2788853B2 (ja) 1994-02-14 1998-08-20 株式会社エクセディ ダンパー装置
JP5718049B2 (ja) * 2007-06-01 2015-05-13 カウンスィル オブ サイエンティフィック アンド インダストリアル リサーチＣｏｕｎｃｉｌ Ｏｆ Ｓｃｉｅｎｔｉｆｉｃ ＆ Ｉｎｄｕｓｔｒｉａｌ Ｒｅｓｅａｒｃｈ 眼および中枢神経系の細菌、真菌、寄生虫およびウイルス感染の同時検出と識別のための新規な方法
WO2010130877A2 (en) * 2009-05-12 2010-11-18 Abacus Diagnostica Oy Method for detecting nucleic acids
EP2270202A1 (en) * 2009-07-03 2011-01-05 John Ikonomopoulos Mycobacterial detection
CA2863819C (en) 2012-02-09 2021-11-23 Memed Diagnostics Ltd. Signatures and determinants for diagnosing infections and methods of use thereof
WO2013148868A1 (en) * 2012-03-30 2013-10-03 Intelligent Medical Devices, Inc. Optimized probes and primers and methods of using same for the binding, detection, differentiation, isolation and sequencing of herpes simplex virus
CN103045761B (zh) * 2012-12-14 2016-01-20 山东省眼科研究所 用于检测感染性眼病致病微生物的试剂盒及检测方法
WO2014186874A1 (en) 2013-05-23 2014-11-27 Yyz Pharmatech, Inc. Methods and compositions for enzyme linked immuno and hybridization mass spectrometric assay
US10303846B2 (en) 2014-08-14 2019-05-28 Memed Diagnostics Ltd. Computational analysis of biological data using manifold and a hyperplane
CN204050005U (zh) * 2014-09-09 2014-12-31 赵潺 一次性负压前房穿刺针
US20170234873A1 (en) 2014-10-14 2017-08-17 Memed Diagnostics Ltd. Signatures and determinants for diagnosing infections in non-human subjects and methods of use thereof
ES2768762T3 (es) 2014-11-05 2020-06-23 Illumina Cambridge Ltd Reducción del daño al ADN durante la preparación de muestras y secuenciación usando agentes quelantes sideróforos
CA2976411A1 (en) * 2014-11-19 2016-05-26 Otsuka Pharmaceutical Co., Ltd. Primer set and method for amplifying exons of pkd1 gene and pkd2 gene
US20170269081A1 (en) 2014-12-11 2017-09-21 Memed Diagnostics Ltd. Marker combinations for diagnosing infections and methods of use thereof
KR101521409B1 (ko) * 2015-01-15 2015-05-18 경북대학교 산학협력단 진균성 및 아메바성 각막염의 원인체를 동시에 검출할 수 있는 다중 중합효소 연쇄반응 프라이머 세트 및 이를 이용한 각막염 유발균 검출 방법
EP3154439A1 (en) * 2015-05-19 2017-04-19 Yaya Diagnostics GmbH Means and methods for the enrichment of nucleic acids
CN108699609A (zh) 2016-03-03 2018-10-23 米密德诊断学有限公司 分析rna用于诊断感染类型
WO2017149548A1 (en) 2016-03-03 2017-09-08 Memed Diagnostics Ltd. Rna determinants for distinguishing between bacterial and viral infections
CN106167833B (zh) * 2016-05-20 2019-09-20 南方医科大学 一种同时检测8种虫媒脑炎病毒的rt-pcr引物和探针组合及试剂盒
CA3027341A1 (en) 2016-07-10 2018-01-18 Memed Diagnostics Ltd. Protein signatures for distinguishing between bacterial and viral infections
US11340223B2 (en) 2016-07-10 2022-05-24 Memed Diagnostics Ltd. Early diagnosis of infections
EP3519833B1 (en) 2016-09-29 2024-08-14 MeMed Diagnostics Ltd. Methods of prognosis and treatment
US11353456B2 (en) 2016-09-29 2022-06-07 Memed Diagnostics Ltd. Methods of risk assessment and disease classification for appendicitis
CN106834548B (zh) * 2017-03-30 2020-03-27 广州基迪奥生物科技有限公司 一种常见眼内感染病毒多重实时荧光pcr检测试剂盒
US10209260B2 (en) 2017-07-05 2019-02-19 Memed Diagnostics Ltd. Signatures and determinants for diagnosing infections and methods of use thereof
WO2019126523A2 (en) * 2017-12-22 2019-06-27 Massachusetts Eye And Ear Infirmary Comprehensive microbial panel for molecular diagnosis of eye infections
KR102297545B1 (ko) * 2020-02-06 2021-09-02 경희대학교 산학협력단 코리스메이트 뮤테이즈 단백질 항체를 포함하는 가시아메바성 각막염의 감별 진단용 조성물 및 이를 이용한 가시아메바성 각막염 진단 키트
CN111763767A (zh) * 2020-06-04 2020-10-13 上海捷诺生物科技有限公司 中枢神经系统感染病原体检测试剂盒及其应用
CN113201599B (zh) * 2021-06-03 2023-03-31 北京大学人民医院 一种基于PCR和nanopore测序检测脑脊液感染哪些病原体的方法
CN114277167A (zh) * 2021-12-31 2022-04-05 杭州千基生物科技有限公司 一种用于细菌性肠道病原体的量子点核酸检测的试剂盒
CN114891870A (zh) * 2022-06-26 2022-08-12 杭州奥明医学检验实验室有限公司 一种基于mNGS检测致癌病原体的方法、系统及装置
CN116144811B (zh) * 2022-12-21 2024-02-20 迪飞医学科技(南京)有限公司 用于检测脑脊液病原的多重引物组、方法和试剂盒
CN116121428A (zh) * 2023-03-17 2023-05-16 郑州安图生物工程股份有限公司 引物探针组合及试剂盒
TWI903264B (zh) * 2023-10-27 2025-11-01 東海大學 黴菌抑制力的體外篩檢方法
KR102909897B1 (ko) * 2023-10-30 2026-01-09 주식회사 엔피켐바이오 헤르페스바이러스 검출용 프라이머 세트
CN120648829B (zh) * 2025-07-16 2026-04-10 武汉贝纳医学科技有限公司 病原检测引物组、试剂盒及在眼部感染病原检测中的应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1450171A (zh) * 2003-05-09 2003-10-22 陶开华 一种检测多种传染病的检测型基因芯片及应用
CN1473940A (zh) * 2002-08-09 2004-02-11 中国人民解放军基因工程研究所 一种限制性荧光标记方法
CN1508264A (zh) * 2002-12-18 2004-06-30 云南大学 一种临床感染性疾病基因芯片诊断方案
CN1896284A (zh) * 2006-06-30 2007-01-17 博奥生物有限公司 一种鉴别等位基因类型的方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639871A (en) 1988-09-09 1997-06-17 Roche Molecular Systems, Inc. Detection of human papillomavirus by the polymerase chain reaction
JPH10323189A (ja) * 1997-05-23 1998-12-08 Toyobo Co Ltd 抗酸菌属細菌の検出または菌種同定用オリゴヌクレオチドおよびその用途
US6514694B2 (en) * 1997-12-19 2003-02-04 Heska Corporation Methods for the detection of encysted parasites
KR100343606B1 (ko) * 1999-05-29 2002-07-12 김정준 마이코박테리아 균종 동정용 올리고뉴클레오티드
US20040121309A1 (en) 2002-12-06 2004-06-24 Ecker David J. Methods for rapid detection and identification of bioagents in blood, bodily fluids, and bodily tissues
US20030027135A1 (en) 2001-03-02 2003-02-06 Ecker David J. Method for rapid detection and identification of bioagents
JP2003144153A (ja) * 2001-11-09 2003-05-20 Gifu Univ 遺伝子検出方法、遺伝子検出用プライマー、ｄｎａマイクロアレイ及び遺伝子検出用キット
WO2004099438A1 (en) 2003-05-07 2004-11-18 Coris Bioconcept Sprl One step oligochromatographic device and method of use
CA2562775C (en) * 2004-04-07 2015-08-04 Access Bio, Inc. Nucleic acid detection system
JP2006129810A (ja) * 2004-11-08 2006-05-25 Canon Inc 感染症起炎菌検出用プローブセット及び担体及び遺伝子検査方法
KR101409193B1 (ko) * 2005-01-31 2014-06-19 가부시키가이샤 야쿠르트 혼샤 알 알엔에이를 표적으로 한 미생물의 정량적 해석방법
EP1951888B1 (en) * 2005-11-09 2012-09-05 PrimeraDx, Inc. Multiplexed quantitative detection of pathogens
CN1995387B (zh) * 2006-11-07 2010-06-23 亚能生物技术（深圳）有限公司 分枝杆菌菌种鉴定基因芯片检测系统
JP5718049B2 (ja) * 2007-06-01 2015-05-13 カウンスィル オブ サイエンティフィック アンド インダストリアル リサーチＣｏｕｎｃｉｌ Ｏｆ Ｓｃｉｅｎｔｉｆｉｃ ＆ Ｉｎｄｕｓｔｒｉａｌ Ｒｅｓｅａｒｃｈ 眼および中枢神経系の細菌、真菌、寄生虫およびウイルス感染の同時検出と識別のための新規な方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1473940A (zh) * 2002-08-09 2004-02-11 中国人民解放军基因工程研究所 一种限制性荧光标记方法
CN1508264A (zh) * 2002-12-18 2004-06-30 云南大学 一种临床感染性疾病基因芯片诊断方案
CN1450171A (zh) * 2003-05-09 2003-10-22 陶开华 一种检测多种传染病的检测型基因芯片及应用
CN1896284A (zh) * 2006-06-30 2007-01-17 博奥生物有限公司 一种鉴别等位基因类型的方法

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KR20100044736A (ko) 2010-04-30
WO2008146306A2 (en) 2008-12-04
JP2010528599A (ja) 2010-08-26
CA2689306A1 (en) 2008-12-04
TW200907057A (en) 2009-02-16
NZ582232A (en) 2012-05-25
CN101541979A (zh) 2009-09-23
JP5718049B2 (ja) 2015-05-13
US20130310279A1 (en) 2013-11-21
MY163053A (en) 2017-08-15
WO2008146306A3 (en) 2009-01-15
KR101866766B1 (ko) 2018-06-18
CN104313180B (zh) 2017-05-24
EP2155909A2 (en) 2010-02-24
IL202459A (en) 2014-09-30
JP2014223077A (ja) 2014-12-04
AU2008256216B2 (en) 2014-07-31
AR110776A2 (es) 2019-05-02
AR066825A1 (es) 2009-09-16
IL202459A0 (en) 2011-08-01
US20110111969A1 (en) 2011-05-12
AU2008256216A1 (en) 2008-12-04
CA2689306C (en) 2019-01-15
MY150954A (en) 2014-03-31
JP5927243B2 (ja) 2016-06-01
US20170275710A1 (en) 2017-09-28
TWI410491B (zh) 2013-10-01
US10584392B2 (en) 2020-03-10
US9777339B2 (en) 2017-10-03
BRPI0812178A2 (pt) 2021-05-04
EP2155909B1 (en) 2018-03-07
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CN104313180A (zh) 2015-01-28
US8465951B2 (en) 2013-06-18

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