BRPI0812178A2 - método para detecção e discriminação simultânea de infecções bacterianas, fúngicas, parasitárias e virais no olho e sistema nervoso central - Google Patents

método para detecção e discriminação simultânea de infecções bacterianas, fúngicas, parasitárias e virais no olho e sistema nervoso central Download PDF

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Publication number
BRPI0812178A2
BRPI0812178A2 BRPI0812178-8A BRPI0812178A BRPI0812178A2 BR PI0812178 A2 BRPI0812178 A2 BR PI0812178A2 BR PI0812178 A BRPI0812178 A BR PI0812178A BR PI0812178 A2 BRPI0812178 A2 BR PI0812178A2
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seq
group
dna sequence
sample
detection
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BRPI0812178-8A
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English (en)
Portuguese (pt)
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Chintalagiri Mohan Rao
Kunchala Sridhar Rao
Puppala Venkat Ramchander
Hajib Naraharirao Madhavan
Savitri Sharma
Gita Satpathy
Venkata Banda Ravi Kumar
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Council Of Scientific & Industrial Research
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Publication of BRPI0812178A2 publication Critical patent/BRPI0812178A2/pt

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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/6895Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/705Specific hybridization probes for herpetoviridae, e.g. herpes simplex, varicella zoster
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2527/00Reactions demanding special reaction conditions
    • C12Q2527/101Temperature
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    • C12Q2537/00Reactions characterised by the reaction format or use of a specific feature
    • C12Q2537/10Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/143Multiplexing, i.e. use of multiple primers or probes in a single reaction, usually for simultaneously analyse of multiple analysis
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q2561/00Nucleic acid detection characterised by assay method
    • C12Q2561/113Real time assay
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    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/16Primer sets for multiplex assays

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
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  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
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  • Genetics & Genomics (AREA)
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  • Physics & Mathematics (AREA)
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  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
BRPI0812178-8A 2007-06-01 2008-05-27 método para detecção e discriminação simultânea de infecções bacterianas, fúngicas, parasitárias e virais no olho e sistema nervoso central BRPI0812178A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN1178/DEL/2007 2007-06-01
IN1178DE2007 2007-06-01
PCT/IN2008/000334 WO2008146306A2 (en) 2007-06-01 2008-05-27 A novel method for simultaneous detection and discrimination of bacterial, fungal, parasitic and viral infections of eye and central nervous system

Publications (1)

Publication Number Publication Date
BRPI0812178A2 true BRPI0812178A2 (pt) 2021-05-04

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BRPI0812178-8A BRPI0812178A2 (pt) 2007-06-01 2008-05-27 método para detecção e discriminação simultânea de infecções bacterianas, fúngicas, parasitárias e virais no olho e sistema nervoso central

Country Status (14)

Country Link
US (3) US8465951B2 (enExample)
EP (1) EP2155909B1 (enExample)
JP (2) JP5718049B2 (enExample)
KR (1) KR101866766B1 (enExample)
CN (2) CN104313180B (enExample)
AR (2) AR066825A1 (enExample)
AU (1) AU2008256216B2 (enExample)
BR (1) BRPI0812178A2 (enExample)
CA (1) CA2689306C (enExample)
IL (1) IL202459A (enExample)
MY (2) MY150954A (enExample)
NZ (1) NZ582232A (enExample)
TW (1) TWI410491B (enExample)
WO (1) WO2008146306A2 (enExample)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2661474B1 (fr) 1990-04-25 1992-06-12 Valeo Double volant amortisseur de torsion pour moteur a combustion interne.
JP2788853B2 (ja) 1994-02-14 1998-08-20 株式会社エクセディ ダンパー装置
CA2689306C (en) * 2007-06-01 2019-01-15 Council Of Scientific & Industrial Research A novel method for simultaneous detection and discrimination of bacterial, fungal, parasitic and viral infections of eye and central nervous system
US20120040349A1 (en) * 2009-05-12 2012-02-16 Piia Von Lode Method for detecting nucleic acids
EP2270202A1 (en) * 2009-07-03 2011-01-05 John Ikonomopoulos Mycobacterial detection
EP3882633A1 (en) 2012-02-09 2021-09-22 MeMed Diagnostics Ltd. Signatures and determinants for diagnosing infections and methods of use thereof
WO2013148868A1 (en) * 2012-03-30 2013-10-03 Intelligent Medical Devices, Inc. Optimized probes and primers and methods of using same for the binding, detection, differentiation, isolation and sequencing of herpes simplex virus
CN103045761B (zh) * 2012-12-14 2016-01-20 山东省眼科研究所 用于检测感染性眼病致病微生物的试剂盒及检测方法
WO2014186874A1 (en) 2013-05-23 2014-11-27 Yyz Pharmatech, Inc. Methods and compositions for enzyme linked immuno and hybridization mass spectrometric assay
CN111624346A (zh) 2014-08-14 2020-09-04 米密德诊断学有限公司 用于预测及/或决定预后的套组
CN204050005U (zh) * 2014-09-09 2014-12-31 赵潺 一次性负压前房穿刺针
US20170234873A1 (en) 2014-10-14 2017-08-17 Memed Diagnostics Ltd. Signatures and determinants for diagnosing infections in non-human subjects and methods of use thereof
US9828627B2 (en) * 2014-11-05 2017-11-28 Illumina Cambridge Limited Reducing DNA damage during sample preparation and sequencing using siderophore chelators
EP3225696B1 (en) * 2014-11-19 2020-06-03 Otsuka Pharmaceutical Co., Ltd. Primer set and method for amplifying exons of pkd1 gene and pkd2 gene
CA2968650A1 (en) 2014-12-11 2016-06-16 Memed Diagnostics Ltd. Marker combinations for diagnosing infections and methods of use thereof
KR101521409B1 (ko) * 2015-01-15 2015-05-18 경북대학교 산학협력단 진균성 및 아메바성 각막염의 원인체를 동시에 검출할 수 있는 다중 중합효소 연쇄반응 프라이머 세트 및 이를 이용한 각막염 유발균 검출 방법
EP3154439A1 (en) * 2015-05-19 2017-04-19 Yaya Diagnostics GmbH Means and methods for the enrichment of nucleic acids
US12338497B2 (en) 2016-03-03 2025-06-24 Memed Diagnostics Ltd. Analyzing RNA for diagnosing infection type
CN108699583B (zh) 2016-03-03 2022-11-01 米密德诊断学有限公司 用于区分细菌和病毒感染的rna决定子
CN106167833B (zh) * 2016-05-20 2019-09-20 南方医科大学 一种同时检测8种虫媒脑炎病毒的rt-pcr引物和探针组合及试剂盒
EP3482201B1 (en) 2016-07-10 2022-12-14 Memed Diagnostics Ltd. Early diagnosis of infections
WO2018011795A1 (en) 2016-07-10 2018-01-18 Memed Diagnostics Ltd. Protein signatures for distinguishing between bacterial and viral infections
EP3519833B1 (en) 2016-09-29 2024-08-14 MeMed Diagnostics Ltd. Methods of prognosis and treatment
US11353456B2 (en) 2016-09-29 2022-06-07 Memed Diagnostics Ltd. Methods of risk assessment and disease classification for appendicitis
CN106834548B (zh) * 2017-03-30 2020-03-27 广州基迪奥生物科技有限公司 一种常见眼内感染病毒多重实时荧光pcr检测试剂盒
US10209260B2 (en) 2017-07-05 2019-02-19 Memed Diagnostics Ltd. Signatures and determinants for diagnosing infections and methods of use thereof
US12195810B2 (en) 2017-12-22 2025-01-14 Massachusetts Eye And Ear Infirmary Comprehensive microbial panel for molecular diagnosis of eye infections
KR102297545B1 (ko) * 2020-02-06 2021-09-02 경희대학교 산학협력단 코리스메이트 뮤테이즈 단백질 항체를 포함하는 가시아메바성 각막염의 감별 진단용 조성물 및 이를 이용한 가시아메바성 각막염 진단 키트
CN111763767A (zh) * 2020-06-04 2020-10-13 上海捷诺生物科技有限公司 中枢神经系统感染病原体检测试剂盒及其应用
CN113201599B (zh) * 2021-06-03 2023-03-31 北京大学人民医院 一种基于PCR和nanopore测序检测脑脊液感染哪些病原体的方法
CN114277167A (zh) * 2021-12-31 2022-04-05 杭州千基生物科技有限公司 一种用于细菌性肠道病原体的量子点核酸检测的试剂盒
CN114891870A (zh) * 2022-06-26 2022-08-12 杭州奥明医学检验实验室有限公司 一种基于mNGS检测致癌病原体的方法、系统及装置
CN116144811B (zh) * 2022-12-21 2024-02-20 迪飞医学科技(南京)有限公司 用于检测脑脊液病原的多重引物组、方法和试剂盒
CN116121428A (zh) * 2023-03-17 2023-05-16 郑州安图生物工程股份有限公司 引物探针组合及试剂盒

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639871A (en) 1988-09-09 1997-06-17 Roche Molecular Systems, Inc. Detection of human papillomavirus by the polymerase chain reaction
JPH10323189A (ja) * 1997-05-23 1998-12-08 Toyobo Co Ltd 抗酸菌属細菌の検出または菌種同定用オリゴヌクレオチドおよびその用途
US6514694B2 (en) * 1997-12-19 2003-02-04 Heska Corporation Methods for the detection of encysted parasites
KR100316095B1 (ko) * 1999-05-29 2001-12-13 김정준 마이코박테리아 균종 동정용 올리고뉴클레오티드
US20040121335A1 (en) 2002-12-06 2004-06-24 Ecker David J. Methods for rapid detection and identification of bioagents associated with host versus graft and graft versus host rejections
US20030027135A1 (en) 2001-03-02 2003-02-06 Ecker David J. Method for rapid detection and identification of bioagents
JP2003144153A (ja) * 2001-11-09 2003-05-20 Gifu Univ 遺伝子検出方法、遺伝子検出用プライマー、dnaマイクロアレイ及び遺伝子検出用キット
CN1329523C (zh) * 2002-08-09 2007-08-01 中国人民解放军基因工程研究所 一种限制性荧光标记方法
CN1508264A (zh) * 2002-12-18 2004-06-30 云南大学 一种临床感染性疾病基因芯片诊断方案
US7932093B2 (en) 2003-05-07 2011-04-26 Coris Bioconcept Sprl One step oligochromatographic device and method of use
CN1195070C (zh) * 2003-05-09 2005-03-30 陶开华 一种检测多种传染病的检测型基因芯片及应用
CA2562775C (en) * 2004-04-07 2015-08-04 Access Bio, Inc. Nucleic acid detection system
JP2006129810A (ja) * 2004-11-08 2006-05-25 Canon Inc 感染症起炎菌検出用プローブセット及び担体及び遺伝子検査方法
PL1845158T3 (pl) * 2005-01-31 2014-02-28 Yakult Honsha Kk Sposób ilościowego oznaczania drobnoustroju ukierunkowanego na rRNA
EP1951888B1 (en) * 2005-11-09 2012-09-05 PrimeraDx, Inc. Multiplexed quantitative detection of pathogens
CN1896284B (zh) * 2006-06-30 2013-09-11 博奥生物有限公司 一种鉴别等位基因类型的方法
CN1995387B (zh) * 2006-11-07 2010-06-23 亚能生物技术(深圳)有限公司 分枝杆菌菌种鉴定基因芯片检测系统
CA2689306C (en) * 2007-06-01 2019-01-15 Council Of Scientific & Industrial Research A novel method for simultaneous detection and discrimination of bacterial, fungal, parasitic and viral infections of eye and central nervous system

Also Published As

Publication number Publication date
KR101866766B1 (ko) 2018-06-18
AR110776A2 (es) 2019-05-02
CN104313180B (zh) 2017-05-24
CN101541979B (zh) 2014-11-05
NZ582232A (en) 2012-05-25
US20130310279A1 (en) 2013-11-21
IL202459A (en) 2014-09-30
WO2008146306A3 (en) 2009-01-15
AU2008256216B2 (en) 2014-07-31
US8465951B2 (en) 2013-06-18
CA2689306C (en) 2019-01-15
MY163053A (en) 2017-08-15
JP5927243B2 (ja) 2016-06-01
US20170275710A1 (en) 2017-09-28
KR20100044736A (ko) 2010-04-30
TWI410491B (zh) 2013-10-01
AU2008256216A1 (en) 2008-12-04
US10584392B2 (en) 2020-03-10
JP2014223077A (ja) 2014-12-04
JP2010528599A (ja) 2010-08-26
IL202459A0 (en) 2011-08-01
US9777339B2 (en) 2017-10-03
WO2008146306A2 (en) 2008-12-04
US20110111969A1 (en) 2011-05-12
CN104313180A (zh) 2015-01-28
JP5718049B2 (ja) 2015-05-13
TW200907057A (en) 2009-02-16
CN101541979A (zh) 2009-09-23
EP2155909B1 (en) 2018-03-07
MY150954A (en) 2014-03-31
AR066825A1 (es) 2009-09-16
EP2155909A2 (en) 2010-02-24
HK1206396A1 (en) 2016-01-08
CA2689306A1 (en) 2008-12-04

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