CN101406453A - 用于口服或局部给药的药物组合物 - Google Patents

用于口服或局部给药的药物组合物 Download PDF

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Publication number
CN101406453A
CN101406453A CNA2008101094369A CN200810109436A CN101406453A CN 101406453 A CN101406453 A CN 101406453A CN A2008101094369 A CNA2008101094369 A CN A2008101094369A CN 200810109436 A CN200810109436 A CN 200810109436A CN 101406453 A CN101406453 A CN 101406453A
Authority
CN
China
Prior art keywords
preparation
chor
cyclosporin
fatty acid
ester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2008101094369A
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English (en)
Chinese (zh)
Inventor
T·安德雷塞克
M·斯图啻利克
A·维拉那
A·杰戈罗夫
J·斯图啻利克
V·玛萨
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ivax LLC
Original Assignee
Ivax LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10859192&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN101406453(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ivax LLC filed Critical Ivax LLC
Publication of CN101406453A publication Critical patent/CN101406453A/zh
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1274Non-vesicle bilayer structures, e.g. liquid crystals, tubules, cubic phases or cochleates; Sponge phases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Dispersion Chemistry (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Epoxy Compounds (AREA)
CNA2008101094369A 1999-08-17 2000-08-17 用于口服或局部给药的药物组合物 Pending CN101406453A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9919288A GB2355656B (en) 1999-08-17 1999-08-17 Pharmaceutical compositions for oral and topical administration
GB9919288.2 1999-08-17

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN00813185A Division CN1382061A (zh) 1999-08-17 2000-08-17 用于口服或局部给药的药物组合物

Publications (1)

Publication Number Publication Date
CN101406453A true CN101406453A (zh) 2009-04-15

Family

ID=10859192

Family Applications (2)

Application Number Title Priority Date Filing Date
CNA2008101094369A Pending CN101406453A (zh) 1999-08-17 2000-08-17 用于口服或局部给药的药物组合物
CN00813185A Pending CN1382061A (zh) 1999-08-17 2000-08-17 用于口服或局部给药的药物组合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN00813185A Pending CN1382061A (zh) 1999-08-17 2000-08-17 用于口服或局部给药的药物组合物

Country Status (40)

Country Link
US (1) US20070190132A1 (enExample)
EP (2) EP1334717B1 (enExample)
JP (2) JP2003507343A (enExample)
KR (2) KR100828747B1 (enExample)
CN (2) CN101406453A (enExample)
AR (2) AR025324A1 (enExample)
AT (2) ATE402691T1 (enExample)
AU (1) AU777740B2 (enExample)
BR (1) BR0013385A (enExample)
CA (2) CA2380951C (enExample)
CO (1) CO5380014A1 (enExample)
CY (1) CY1105318T1 (enExample)
CZ (2) CZ296170B6 (enExample)
DE (2) DE60018081T2 (enExample)
DK (2) DK1334717T3 (enExample)
EE (2) EE04954B1 (enExample)
EG (1) EG23994A (enExample)
ES (2) ES2311077T3 (enExample)
GB (1) GB2355656B (enExample)
HK (1) HK1049629A1 (enExample)
HR (1) HRP20020154B1 (enExample)
HU (1) HUP0203236A3 (enExample)
IL (4) IL158108A0 (enExample)
JO (1) JO2324B1 (enExample)
MX (1) MXPA02001631A (enExample)
NO (2) NO20020760L (enExample)
NZ (1) NZ517271A (enExample)
PE (1) PE20010636A1 (enExample)
PL (1) PL192769B1 (enExample)
PT (2) PT1210119E (enExample)
RU (2) RU2279894C2 (enExample)
SA (1) SA00210487B1 (enExample)
SG (1) SG143019A1 (enExample)
SI (1) SI1210119T1 (enExample)
SK (2) SK2482002A3 (enExample)
TN (1) TNSN00173A1 (enExample)
UA (2) UA72539C2 (enExample)
UY (1) UY26303A1 (enExample)
WO (1) WO2001012229A1 (enExample)
ZA (2) ZA200308221B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112426403A (zh) * 2020-12-09 2021-03-02 南京天纵易康生物科技股份有限公司 一种口腔溃疡凝胶及其制备方法和应用

Families Citing this family (20)

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GB2355656B (en) * 1999-08-17 2004-04-07 Galena As Pharmaceutical compositions for oral and topical administration
FR2826261B1 (fr) * 2001-06-26 2005-03-25 Lmd Composition a usage topique comprenant un produit cytotoxique et son utilisation dans le traitement de l'alopeche
DE10154464B4 (de) * 2001-11-08 2005-10-20 Max Delbrueck Centrum Oral verabreichbare pharmazeutische Zubereitung umfassend liposomal verkapseltes Taxol
KR20030065831A (ko) * 2002-02-01 2003-08-09 주식회사 태평양 사이클로스포린을 함유한 지속 방출형 약학적 조성물
US7101576B2 (en) * 2002-04-12 2006-09-05 Elan Pharma International Limited Nanoparticulate megestrol formulations
US9101540B2 (en) 2002-04-12 2015-08-11 Alkermes Pharma Ireland Limited Nanoparticulate megestrol formulations
EP1935407A1 (en) * 2002-12-03 2008-06-25 Elan Pharma International Limited Low viscosity liquid dosage forms
JP4518042B2 (ja) * 2002-12-04 2010-08-04 日油株式会社 コエンザイムq10を含有する水溶性組成物の製造方法
EP1582206A4 (en) * 2002-12-04 2010-09-22 Nisshin Pharma Inc WATER-SOLUBLE COMPOSITION WITH COENZYM Q10
SI1585548T1 (sl) 2002-12-09 2018-11-30 Abraxis Bioscience, Llc Sestave in metode odmerjanja farmakoloških sredstev
US6979672B2 (en) * 2002-12-20 2005-12-27 Polichem, S.A. Cyclosporin-based pharmaceutical compositions
TW200616681A (en) * 2004-10-05 2006-06-01 Recordati Ireland Ltd Lercanidipine capsules
US8236286B2 (en) * 2004-10-20 2012-08-07 Kao Corporation Liquid compositions for the oral cavity
WO2006091780A2 (en) * 2005-02-24 2006-08-31 Elan Pharma International Limited Nanoparticulate formulations of docetaxel and analogues thereof
BRPI0921654A2 (pt) * 2008-11-28 2016-02-10 Advance Holdings Ltd formulação farmacêutica
ES2403380T3 (es) * 2009-03-12 2013-05-17 Lectio Pharmaentwicklungs- Und Verwertungs Gmbh Formulación farmacéutica que comprende cetoprofeno y un éster de polioxialquileno de un hidroxiácido graso
KR101100933B1 (ko) * 2009-04-23 2012-01-02 한국기술교육대학교 산학협력단 솔더 볼 제거 장치
EP3274054A1 (en) * 2015-03-27 2018-01-31 Arch Personal Care Products, L.P. Viscosity building composition for personal care products
TW202406566A (zh) * 2022-05-02 2024-02-16 日商中外製藥股份有限公司 包含用於與界面活性劑結合使用之胜肽化合物的組合物
CN119770478B (zh) * 2024-12-31 2025-12-19 美济生物医药(广州)有限公司 紫杉醇口服药物组合物、制剂及其制备方法和应用

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US5342625A (en) * 1988-09-16 1994-08-30 Sandoz Ltd. Pharmaceutical compositions comprising cyclosporins
US6007840A (en) * 1988-09-16 1999-12-28 Novartis Ag Pharmaceutical compositions comprising cyclosporins
KR0148748B1 (ko) * 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 사이클로스포린을 함유하는 약학조성물
CZ288631B6 (cs) * 1996-01-18 2001-08-15 Galena, A. S. Léčivé přípravky s obsahem cyklosporinu
CZ288739B6 (cs) * 1996-08-01 2001-08-15 Galena, A. S. Cyklosporin obsahující léčivé přípravky
CZ283516B6 (cs) * 1996-09-12 1998-04-15 Galena A.S. Léčivé přípravky, zejména pro vnitřní aplikaci, ve formě samomikroemulgujících terapeutických systémů
NZ337316A (en) * 1997-03-12 2001-06-29 Abbott Lab Hydrophilic binary systems comprising cyclosporine, hydrophilic phase and a surfactant for the administration of cyclosporine
WO1998040051A1 (en) * 1997-03-12 1998-09-17 Abbott Laboratories Lipophilic binary systems for the administration of lipophilic compounds
NZ502569A (en) * 1997-07-29 2002-05-31 Upjohn Co Self-emulsifying formulation for lipophilic compounds comprising a mixture of diglyceride and monoglyceride in a ratio of 9:1 to 6:4
US6063762A (en) * 1997-12-05 2000-05-16 Chong Kun Dang Corp. Cyclosporin-containing microemulsion preconcentrate composition
US20030216303A1 (en) * 1998-03-06 2003-11-20 Michael Ambuhl Emulsion preconcentrates containing cyclosporin or a macrolide
GB2355656B (en) * 1999-08-17 2004-04-07 Galena As Pharmaceutical compositions for oral and topical administration

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112426403A (zh) * 2020-12-09 2021-03-02 南京天纵易康生物科技股份有限公司 一种口腔溃疡凝胶及其制备方法和应用
CN112426403B (zh) * 2020-12-09 2021-09-17 南京天纵易康生物科技股份有限公司 一种口腔溃疡凝胶及其制备方法和应用

Also Published As

Publication number Publication date
MXPA02001631A (es) 2003-07-14
ES2237443T3 (es) 2005-08-01
HUP0203236A2 (hu) 2003-01-28
NO20020760L (no) 2002-04-16
DK1210119T3 (da) 2005-06-20
AR025324A1 (es) 2002-11-20
EE200300371A (et) 2003-10-15
IL148200A (en) 2007-12-03
EE04955B1 (et) 2008-02-15
EE04954B1 (et) 2008-02-15
HK1049629A1 (zh) 2003-05-23
HUP0203236A3 (en) 2004-06-28
HRP20020154B1 (en) 2006-07-31
KR20050095651A (ko) 2005-09-29
RU2003133451A (ru) 2005-04-20
SI1210119T1 (en) 2005-06-30
SG143019A1 (en) 2008-06-27
AU6461300A (en) 2001-03-13
KR20020059367A (ko) 2002-07-12
EG23994A (en) 2008-03-10
GB2355656B (en) 2004-04-07
JP2004238399A (ja) 2004-08-26
ZA200308221B (en) 2004-09-29
EP1210119B1 (en) 2005-02-09
AU777740B2 (en) 2004-10-28
UA75926C2 (en) 2006-06-15
CZ2002575A3 (cs) 2003-05-14
JP2003507343A (ja) 2003-02-25
GB2355656A (en) 2001-05-02
PT1334717E (pt) 2008-10-09
IL148200A0 (en) 2002-09-12
DE60018081T2 (de) 2006-01-05
ATE402691T1 (de) 2008-08-15
NO20020760D0 (no) 2002-02-15
US20070190132A1 (en) 2007-08-16
CY1105318T1 (el) 2010-03-03
ATE288766T1 (de) 2005-02-15
RU2279894C2 (ru) 2006-07-20
CZ296591B6 (cs) 2006-04-12
EE200200075A (et) 2003-04-15
SK2482002A3 (en) 2002-12-03
CA2380951A1 (en) 2001-02-22
PT1210119E (pt) 2005-05-31
SK286083B6 (sk) 2008-03-05
UA72539C2 (en) 2005-03-15
CA2380951C (en) 2010-03-23
PL353445A1 (en) 2003-11-17
DK1334717T3 (da) 2008-11-24
GB9919288D0 (en) 1999-10-20
EP1210119A1 (en) 2002-06-05
KR100828748B1 (ko) 2008-05-09
PE20010636A1 (es) 2001-06-02
EP1334717A3 (en) 2004-01-02
DE60322454D1 (de) 2008-09-11
KR100828747B1 (ko) 2008-05-09
NO20034778L (no) 2002-04-16
TNSN00173A1 (en) 2005-11-10
DE60018081D1 (de) 2005-03-17
CO5380014A1 (es) 2004-03-31
CZ296170B6 (cs) 2006-01-11
IL158108A (en) 2010-04-15
CA2452118A1 (en) 2001-02-22
EP1334717A2 (en) 2003-08-13
PL192769B1 (pl) 2006-12-29
AR043106A2 (es) 2005-07-20
WO2001012229A1 (en) 2001-02-22
JO2324B1 (en) 2005-09-12
BR0013385A (pt) 2002-05-07
NO20034778D0 (no) 2003-10-24
NZ517271A (en) 2004-02-27
RU2279895C2 (ru) 2006-07-20
CN1382061A (zh) 2002-11-27
EP1334717B1 (en) 2008-07-30
SA00210487B1 (ar) 2006-09-10
UY26303A1 (es) 2001-03-16
ZA200201315B (en) 2004-06-30
IL158108A0 (en) 2004-03-28
ES2311077T3 (es) 2009-02-01
HRP20020154A2 (en) 2003-12-31

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