CN101087625A - 用于药物供给的装置、系统和方法 - Google Patents

用于药物供给的装置、系统和方法 Download PDF

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CN101087625A
CN101087625A CNA2004800444581A CN200480044458A CN101087625A CN 101087625 A CN101087625 A CN 101087625A CN A2004800444581 A CNA2004800444581 A CN A2004800444581A CN 200480044458 A CN200480044458 A CN 200480044458A CN 101087625 A CN101087625 A CN 101087625A
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CN101087625B (zh
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埃里克·S·埃德华兹
伊万·T·埃德华兹
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kaleo Inc
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Abstract

一些示意性实施方式包括一种装置，其包括：压缩气体容器；多个适于存储液体药物的药水瓶，每个药水瓶限定了纵向轴线，多个药水瓶的这些纵向轴线平行并且非同轴，多个药水瓶与气体容器中的内容物的致动部分流体偶联；以及多个活塞，每个活塞适于在多个药水瓶中的相应药水瓶内移动，多个活塞适于响应压缩气体容器中的内容物的致动部分的放出而传送多个药水瓶中的至少一部分液体药物并使其穿过可以伸入患者体内的针。

Description

用于药物供给的装置、系统和方法
附图说明
通过以下参照示意性附图对某些示意性实施方式的详细描述将会更容易了解多种可行的实施方式，图中：
图1是系统1000的示意性实施方式的透视图；
图2是系统1000的示意性实施方式的正视图；
图3是系统1000的示意性实施方式的侧视图；
图4是处于第一操作位置的系统1000的示意性实施方式沿图3中的线A-A截取的横截面图；
图5是处于第二操作位置的系统1000的示意性实施方式沿图3中的线A-A截取的横截面图；
图6是处于第三操作位置的系统1000的示意性实施方式沿图3中的线A-A截取的横截面图；
图7是处于第四操作位置的系统1000的示意性实施方式沿图3中的线A-A截取的横截面图；
图8是处于第五操作位置的系统1000的示意性实施方式沿图3中的线A-A截取的横截面图；
图9是处于第六操作位置的系统1000的示意性实施方式沿图3中的线A-A截取的横截面图；
图10是方法10000的示意性实施方式的流程图；
图11是系统1000的示意性实施方式的透视图；
图12是沿图11中的线B-B截取的透视横截面图；
图13是致动杆2200的示意性实施方式的透视图；
图14是沿图3中的线A-A截取的排气机构8000的示意性实施方式的横截面图。
定义
当在此采用以下术语时，适用附加的定义：
致动部分—使某物起作用的部分。
致动锁—一种适于防止致动的装置，例如可枢转、可平移、带有键、可压缩的、和/或可拆除的锁。
致动件—使某物起作用的机构。
适于—适合或适用于特定目的。
设备—机构和/或装置。
臂—细长的结构件，其不必仅为线性的。
可以—在至少一些实施方式中能够。
通道—用于一种或多种流体的管道。
压缩气体—气态形式的基本上得到增压的物质，例如氦、氮、和/或二氧化碳等。
包括—包含但不局限。
包含—在其中容纳。
内容物—含有的压缩气体。
信用卡—一种卡片(通常为塑料的)，其向销售商保证使用它的人具有满意的信用等级并且发行者将负责使销售商接受对所提供的商品和/或服务的偿付。通常尺寸测量的长度从大约3英寸到大约4英寸，例如大约3.40英寸、3.375英寸、85毫米等，宽度从大约1.75英寸到大约2.75英寸，例如大约2.10英寸、2.2125英寸、2.5英寸、55毫米等。
排放—从密闭件中释放；放出。
喷射—排出。
逸出口—用于气体排出的开口。
喷射压力—施加在液体面积上的力，该力足以以预定方式排出液体。
伸出—移动出去和/或远离。
可伸出—能够移动出去和/或远离。
流体—气体和/或液体。
可流体偶联—能够经由流体相关联。
易碎物—一种能够被打破和/或穿透以使流体从中流过的装置。
壳体—封盖、防护、容纳和/或支承的物体。
响应于—直接和/或间接响应于。
指示—表明、标记、表示、代表、证明、显示、声明、阐明、规定、说明、展出、提出、揭示、披露、和/或展示。
指示器—指示的装置和/或物质。
液体药剂—基本上为液体形式的药、药剂、药品、药物、处方、解毒剂、抗蛇毒血清、激素、兴奋剂、血管扩张剂、麻醉剂、和/或营养供应物。
可以—在至少一些实施方式中允许。
针—用于注射的中空、细长、尖端器具，包括插管。
非同轴—不具有共同的线性轴线。
患者—液体药物的接收者，例如人、哺乳动物、动物等。
活塞—可以通过流体压力或者克服流体压力移动的滑动件。
可枢转—能够枢转。
多个—具有复数和/或超过一个的状态。
预定的—预先制定的。
穿孔器—一种适于采用基本上尖和/或锥形的点、尖端、边缘等穿透的装置。
推进器—一种适于将流体压力转化为机械运动的装置。
缩回—向内拉。
贮存器—用于存储和/或引导流体移动的容器或腔。
弹簧—弹性装置例如线卷，其在得到压缩或伸长之后恢复其初始形状。
情形—状态或条件。
基本上—很大程度上。
系统—机构、装置、数据、和/或指令的集成件，该集成件被设计成完成一项或多项特定功能。
尖端—终端。
传送—从一个位置输送到另一位置。
可平移—能够从一个位置传送到另一位置和/或相对于其它某物移动。
阀—通过打开、闭合、和/或阻塞口和/或通道调节穿过管道和/或穿过孔的流量的装置。
排出—从密闭件中释放。
药水瓶—可封闭的容器。
详细描述
例如通过摄食、吸气和/或注射遭受变态反应原、毒素和/或其它物质侵害会导致一些和/或所有的人和/或动物产生剧烈的反应。例如，某些人对某些物质例如花生、贝虾类、特殊药物、某些蛋白质、蜂毒、虫咬等过敏。对侵害物的过敏反应会导致过敏性休克，从而引起血压急剧下降、荨麻疹和/或由严重的气道收缩引起的实质上的呼吸困难。作为另一示例，某些神经毒剂的吸入会导致严重的生理损伤。
对这些侵害物做出快速反应会防止伤害和/或死亡。例如，对导致过敏性休克的侵害物做出反应，注射肾上腺素(也就是肾上腺素adrenaline)可以基本上和/或完全缓解反应。另一示例是，注射对神经毒剂的解毒剂可以极大地降低和/或消除侵害物的潜在危害。另一示例是，某些药物例如β-阻断药、血液稀释剂、硝化甘油、抗组胺剂、胰岛素和鸦片样物质等的快速注射可以基本上解除多种危险的医疗状态。
因此，一定的示意性实施方式提供了用于快速注射药物的系统、装置和/或方法。
一定的示意性实施方式包括一种装置，其包括：压缩气体容器；多个适于存储液体药物的药水瓶，每个药水瓶限定了纵向轴线，多个药水瓶的这些纵向轴线平行并且非同轴，多个药水瓶与气体容器中的内容物的致动部分流体偶联；和多个活塞，每个活塞适于在多个药水瓶中的相应药水瓶内移动，多个活塞适于响应压缩气体容器中的内容物的致动部分的放出而传送多个药水瓶中的液体药物的至少一部分并使其穿过可伸入患者体内的针。一定示例性实施例包括一种具有多个动作的方法，包括：放出压缩气体容器中的内容物的致动部分，所述压缩气体容器容纳在装置中；响应所述放出动作，在药水瓶内移动活塞，该药水瓶是容纳在装置内的多个药水瓶中的一个，每个药水瓶适于存储液体药物，每个药水瓶限定了纵向轴线，多个药水瓶的这些纵向轴线平行并且非同轴，多个药水瓶与气体容器中的内容物流体偶联；以及传送药水瓶中的液体药物并使其穿过可以伸入患者体内的针。
图1，图2和图3分别是系统1000的示意性实施方式的透视图、正视图和侧视图，所述系统1000包括壳体1100，并在一些可操作的实施方式中可以包括通过致动防护装置1200与致动板1300分隔的手持部分1800。致动防护装置1200可以防止系统1000的意外致动。壳体1100可以由耐用材料例如不锈钢、铝、聚碳酸酯等制成以保护压缩气体容器、药物、注射装置和/或系统1000的使用者。注射装置可以通过流体压力例如通过压缩气体提供的压力致动，所述压缩气体在完成其致动任务之后可以经由排气开口例如经由状态指示器1400排出壳体1100。
可以通过状态指示器1400确定系统1000的状态，所述状态指示器可以例如通过UV屏蔽的、感光的和/或半透明的窗口提供壳体1100内部的观察。可以通过窗口观察的是通过壳体1100承载的药物的状态、用于药物的针和/或注射装置的位置、和/或系统1000的致动状态。例如，如果药物已经过期达到退色的程度，这种过期可能或不可能使药物失效、有害等，则状态指示器1400可以确定这种状态。在一些示意性实施方式中，气体可以经由状态指示器1400和/或壳体1100上另外的开口排出壳体1100。
系统1000的一些示意性实施方式可以提供紧凑的药物供给机构，其高效和/或快速地供给规定剂量。系统1000的长度(L)和宽度(W)可以与信用卡类似，并且厚度(T)可以小于一英寸。因而，系统1000的一些示意性实施方式可以提供一种常规携带、易于使用、易于致动的药物供给装置，其几乎不需要任何培训就可以安全携带、使用和/或分配。
为了有助于使用者将系统1000定位在准确的方向以进行注射，系统1000和/或壳体1100可以提供多种触觉提示。例如，壳体1100的顶部1110可以是圆形，并且壳体1100的致动板1300的底部1120可以是平的。还可以采用其它触觉提示例如凸出部、肋、凹槽、间隙、糙面、凹痕等。
图4是系统1000的示意性实施方式处于第一操作位置沿图3中的线A-A截取的横截面图。图5，6，7，8和9表示图4所示系统1000分别处于第二、第三、第四、第五和第六操作位置。
系统1000可以包括壳体1100、手持部分1800、致动防护装置1200和/或致动板1300。系统1000可以包括系统致动器2000、气体贮存器3000、药物致动器4000、药物存储组件5000、药物承载器9000，针组件6000、使用指示器7000、和/或排气机构8000等。
在拆除、释放、旋转和/或重新定位致动防护装置1200时，系统致动器2000适于快速放出压缩气体容器中内容物的致动部分。例如，系统致动器2000可以包括压缩气体容器2400，其初始可以包含压缩气体2500，其致动部分可以通过经由穿孔器2700的一点穿过出气口2600从容器2400中得到释放。在拆除和/或重新定位致动防护装置1200时，致动板1300可以移动到更靠近和/或接触手持部分1800。在拆除和/或重新定位致动防护装置1200时，气体容器2400可以经过预压缩弹簧2300的伸长和/或致动杆2200的移动达到与穿孔器2700的接触。因而，致动防护装置1200可以防止系统1000的意外致动和/或气体容器2400中的内容物2500的致动部分的无意中放出。
一旦已经穿破出气口2600，则压缩气体2500的致动部分会从容器2400中逸出并经由气体贮存器3000例如气体通道3100流动。流动的气体会与药物致动器4000相遇和/或向其施加气体压力，所述药物致动器可以包括在由壁1520限定的套筒1500内移动的推进器4100。套筒1500可以由金属、不锈钢、铝、塑料、聚碳酸酯等构成。密封件4200例如O形环可以防止气体例如通过推进器4100和/或从壳体1100中泄漏。因而，推进器4100可以作为在圆筒内移动的活塞，尽管如此不必要求套筒1500的横截面形式一定是圆的。
药物致动器4000可以与药物存储组件5000连接。例如，药物致动器4000可以包括多个柱塞4300，每个柱塞可以利用在包含液体药物5200的相应药水瓶5100内密封滑动和/或移动的活塞4400包覆。例如，响应由压缩气体容器2400中的内容物2500的致动部分施加的压力，推进器4100可以促使柱塞4300和/或活塞4400同时移动。柱塞4300、活塞4400和/或药水瓶5100的相应组数可以是2，3，4，5，6或更多。活塞4400可以由弹性、耐用和/或密封材料例如橡胶制成。多个柱塞中的每个柱塞4300可以限定纵向轴线，多个柱塞的纵向轴线(例如轴线4310，4320，4330，4340)平行、非同轴和/或共面。
多个药水瓶中的每个药水瓶5100可以是具有基本上圆形和/或基本上椭圆形横截面形状的基本上的圆柱形。因而，每个药水瓶5100可以限定纵向轴线，多个药水瓶的纵向轴线平行、非同轴和/或共面。每个药水瓶的纵向轴线可以与其相应柱塞的纵向轴线同轴。
每个药水瓶可以在一端包覆易碎物5300，该易碎物可以在活塞4400对药物5200产生足够的压力时破裂，由此使药物5200的至少一部分流出药水瓶5100并流入药物承载器9000。因而，多个药水瓶可以与气体容器2400中的内容物2500的致动部分流体偶联。
药物承载器9000可以保持每个药水瓶5100并且可以在套筒1500内移动。药物承载器9000可以包括适于在药物5200从其相应药水瓶5100中排出时接收该药物5200并将其引导到共用导管9300内的多个通道9200。药物承载器9000可以与针组件6000和/或使用指示器7000连接。
从共用导管9300中，药物5200可以进入针组件6000，例如进入单个针6100内，经由该针药物可以到达针尖6200。当药物致动器4000和/或药物承载器9000朝向致动板1300被驱动时，针尖6200可以穿过针鞘6300的端部6400并使致动板1300在针口1340处退出。
参照图5，当致动板1300移动到更靠近手持部分1800时，鞘座1330可以与鞘尖6400形成接触，由此促使鞘6300弯折和/或破碎。当致动板1300与手持部分1800形成接触时，板止动件1320可以达到药物承载器止动件9400，同时承载器弹簧1600得到压缩。
参照图6，当气体容器2400中的内容物2500的至少一部分逸出时，其可以流过通道3100。仍然相对得到增压的气体开始在推进器41 00之后积聚以形成膨胀气体腔3200并促使药物致动器4000、药物存储组件5000和药物承载器9000一起在套筒1500内滑动。当药物致动器4000、药物存储组件5000和药物承载器9000滑动到更靠近致动板1300时，弹簧1600在板止动件1320与药物承载器止动件9400之间逐渐得到压缩。当药物致动器4000、药物存储组件5000和药物承载器9000滑动到更靠近致动板1300时，针尖6200可以进一步从致动板1300伸出，且针鞘6300可以进一步被压缩和/或变形。当到达最后的延伸点时，针尖6200可以从壳体1100伸长大约0.25毫米到大约20毫米，包括其间的所有值和子范围，例如达到大约2毫米、大于大约5毫米、从大约5.13毫米到大约9.98毫米等。
参照图7，当气体腔3200继续膨胀时，药物承载器9000可以得到驱动直至药物承载器止动件9400接触致动板止动件1300，由此防止药物承载器9000的进一步移动。在那时，气体腔3200另外的膨胀会导致药物致动器4000、推进器杆4100、柱塞4300和/或活塞4400开始相对于药物存储组件5000移动，由此在药水瓶5100内产生喷射压力，和/或由此使易碎物5300破裂并使药物5200进入药物承载器9000，并且开始流动通过药物通道9200、药物导管9300、针6100、和/或离开针尖6200并进入患者体内。备选地，可以由定位在药物导管9300与针6100连接处或其附近的易碎物代替和/或增加易碎物5300。易碎物5300可以由潜在具有预定屈服强度的薄的、已教导的(taught)、弹性、耐用和/或密封材料例如橡胶、例如染色丁基橡胶制成，和/或由潜在具有预定屈服强度的相对脆性的材料例如陶瓷、某些塑料、例如聚苯乙烯等制成。
当药物承载器止动件9400接触致动板止动件1300时，药物承载器钩9600可以与使用指示器7000中的接合接收器7100接合。
参照图8，当气体腔3200继续膨胀时，药物致动器4000、推进器杆4100、柱塞4300和/或活塞4400可以继续移动直至它们完成在药物存储组件5000内的移动，由此将预定剂量的药物5200排出药水瓶5100、排出针组件6000、排到壳体1100外部、和/或排入患者体内。当气体腔3200达到其最大尺寸时，药物致动器4000、推进器杆4100、柱塞4300和/或活塞4400可以继续移动直至它们完成相对于药物承载器9000的移动，由此促使气体释放致动器9700与气体释放阀8200接合。气体释放致动器9700与气体释放阀8200的接合会促使气体腔3200内的气体排出气体腔3200、排放远离活塞4400和/或例如经由定位在壳体1100上的状态指示器1400和/或气体逸出口从系统1000和/或壳体1100中排空。
参照图8和图9，当足量的气体从气体腔3200中排出时，由气体施加在气体腔3200中的压力降低直至由气体施加在药物致动器4000上的力小于压缩弹簧1600的力。因而，弹簧(多个弹簧)1600开始伸长，由此使药物承载器9000、药水瓶组件5000和药物致动器4000移动远离致动板1300并有助于从气体腔3200中排空气体。当药物承载器9000移动时，使用指示器7000可以因药物承载器钩9600与使用指示器7000内的接合接收器7100和/或接合锁扣7200的接合关系而与药物承载器一起移动。当使用指示器7000移动远离致动板1300时，鞘6300可以与其一起移动，由此在鞘尖6400与针口1340之间形成间隙，并由此露出致动板1300之前不可见的有色部分1350和/或提供系统1000已经使用过(以及其药物可能基本上排空)的指示，由此阻止企图进一步使用系统1000。
当药物承载器9000移动远离致动板1300时，针6100可以缩进未弯折和/或未变形的鞘6300内达到其初始形状。最后，针6100可以完全缩进到壳体1100的边界内，由此用于在初始注射之后防止无意中产生的针刺和/或潜在降低和/或消除尖端危险。
在一些示意性实施方式中，系统致动器2000可以包括手指触发、可扭动、可枢转和/或杠杆操作的机构。例如，系统致动器2000可以包括拧入出气口2600内的可转动手柄。在一些示意性实施方式中，系统致动器2000可以是位于壳体一侧的手指扳机。
图10是用于操作药物供给装置的方法10000的示意性实施方式的流程图。在动作10100，释放装置的致动锁。在动作10200，释放压缩气体容器中的内容物的致动部分。在动作10300，通过由释放的气体提供的压力，针从装置中伸出。在动作10400，通过由释放的气体提供的压力，活塞向存储在多个药水瓶中的一个内的药物施加压力。在动作10500，包含药水瓶中药物的易碎物破裂。在动作10600，药物通过针从药水瓶中流出并流入患者体内。在动作10700，一旦排出和/或注射了预定剂量，则针从患者体内抽回并缩进到装置预先使用的边界内。在动作10800，使装置不可以用于另外的注射和/或指示为之前使用过。
图11是系统1000的示意性实施方式的透视图，表示从壳体1100上拆除致动防护装置1200，使得致动防护装置1200不再分隔致动板1300与手持部分1800。致动防护装置1200可以包括可握持部分1220，其可以由使用者握持以拉动致动防护装置1200远离壳体1100，由此例如通过对着使用者大腿拍打致动板1300使系统1000致动。致动防护装置1200可以包括致动杆分离部分1240，其在致动防护装置1200安装在壳体1100上时保持分隔致动杆叉2240。致动防护装置1200可以包括防护部分1260，其可以在系统1000不使用和/或当系统1000未使用过时分隔致动板1300与手持部分1800。
图12是沿图11中的线B-B截取的透视横截面图，并且图13是致动杆2200的示意性实施方式的透视图。参照图12和13，系统1000可以包括壳体1100、致动板1300以及系统致动器2000，该系统致动器可以包括叉挤压器1390、致动杆2200、叉保持器2100、弹簧2300、上弹簧保持器2260、气体容器2400、出气口2600、和/或穿孔器2700。当例如通过对着使用者大腿、臀部和/或臂拍打壳体致动板而使致动板1300紧紧压靠在使用者身体上时，叉挤压器1390可以将致动杆2200的叉2240上的叉尖2200相向压紧。注意到叉尖2200可以具有三角形、楔形、角形和/或截头圆锥形形状。当叉尖2200沿叉挤压器1390成角度的V形槽滑动时，叉锁扣2230可以基本上与叉保持器2100松动接触。这样可以使压缩弹簧2300快速将致动杆2200和气体容器2400压向穿孔器2700，该穿孔器穿入出气口2600，由此使气体从气体容器2400逸出。尽管可以采用许多不同类型的容器，可以从Leland Limited，Inc.of South Plainfield，NJ得到一种示意性的气体容器。
图14是沿图3中的线A-A截取的系统1000的排气机构8000的示意性实施方式的横截面图。系统1000可以包括手持部分1800、致动板1300、套筒1500。当活塞4440处于它们移动的极限附近时，药物5200可以沿经过易碎物5300延伸的药物路径5900排出，穿过药物通道9200、药物导管9300和针6100并例如在皮下、在肌肉内和/或在大约0.25毫米到大约20毫米的深度进入使用者体内，所述深度包括两点值之间的所有值和子范围，例如达到2毫米、大于5毫米等。
当活塞4440处于它们移动的极限附近时，气体释放致动器9700与气体释放阀8200的接合会促使压缩弹簧8300移动阀臂，使得O形环8400被迫远离其座8500。这一移动露出通道8600，通过该通道气体可以沿气体排空路径8900排出气体腔3200，所述气体排空路径在套筒内壁1520与药物承载器9000的外壁9100之间延伸。最后，气体排空路径8900可以在手持部分1800与致动板1300之间延伸。同样，可以越过座8500布置由橡胶或任何其它弹性材料制成的备选实施方式的阀8200以提供密封，一旦气体释放致动器9700与阀8200相互作用，该密封使阀8200可以向上弯曲或折叠远离座8500，从而促使气体经由通道8600逸出。
本领域技术人员通过阅读以上提出对一些示意性实施方式的详细描述和附图将会很容易地了解到其它实施方式。将会认识到可以存在多种变型、修改以及另外的实施方式，因此所有的这些变型、修改和实施方式被认为是处于本申请的精神和范围内。例如，无论本申请的任何部分(例如名称、领域、背景、发明内容、摘要、附图等)的内容如何，除非做出相反的清楚规定，否则不需要在此或在要求优先权的任何申请的任何权利要求中包含任何特定描述或示出的动作或构件、任何所述动作的特定顺序、或者任何所述构件的特定相互关系。而且，任何动作都可以重复、任何动作都可以通过多个机构完成、和/或任何构件都可以复制。此外，任何动作或构件都可以被省去，动作顺序可以改变，和/或构件的相互关系可以改变。因而，说明和附图实质上被认为是示意性的，而不是限制性的。而且，当在此描述任何数量或范围时，除非有其它清楚的规定，否则该数量或范围是大致值。当在此描述任何范围时，除非有清楚的规定，否则该范围包括其中的所有值以及其中的所有子范围。已经在此引入作为参考的任何文献(例如美国专利、美国专利申请、书、文章等)中的任何信息仅仅在这些信息与在此提出的其它说明和附图之间不存在任何矛盾的程度上通过参考得到引入。如果存在矛盾，包括使在此或其优先权中的任何权利要求无效的矛盾，则通过参考文献引入的任何所述矛盾的信息明确规定不通过在此引入作为参考。
权利要求书(按照条约第19条的修改)
1.一种装置，包括：
压缩气体容器；
适于放出压缩气体容器中的内容物的致动部分的致动器；
多个适于存储液体药物的药水瓶，每个药水瓶限定了纵向轴线，多个药水瓶的这些纵向轴线平行并且非同轴，多个药水瓶与气体容器中的内容物的致动部分流体偶联；
多个活塞，每个活塞适于在多个药水瓶中的相应药水瓶内移动，多个活塞适于响应压缩气体容器中的内容物的致动部分的放出而传送多个药水瓶中的液体药物并使其穿过单个针；以及
适于容纳压缩气体容器、多个药水瓶以及多个活塞的壳体，该壳体限定了大致与信用卡相等的长度和宽度以及小于一英寸的厚度。
2.一种装置，包括：
压缩气体容器；
多个适于存储液体药物的药水瓶，每个药水瓶限定了纵向轴线，多个药水瓶的这些纵向轴线平行并且非同轴，多个药水瓶与气体容器中的内容物的致动部分流体偶联；以及
多个活塞，每个活塞适于在多个药水瓶中的相应药水瓶内移动，多个活塞适于响应压缩气体容器中的内容物的致动部分的放出而传送多个药水瓶中的至少一部分液体药物并使其穿过可以伸入到患者体内的针。
3.如权利要求2所述的装置，其特征在于，还包括多个适于向针输送多个药水瓶中的至少一部分药物的通道。
4.如权利要求2所述的装置，其特征在于，还包括适于容纳压缩气体容器、多个药水瓶和多个活塞的壳体。
5.如权利要求2所述的装置，其特征在于，还包括适于容纳压缩气体容器、多个药水瓶以及多个活塞的壳体，该壳体限定了大致与信用卡相等的长度和宽度以及小于一英寸的厚度。
6.如权利要求2所述的装置，其特征在于，还包括适于容纳压缩气体容器、多个药水瓶以及多个活塞的壳体，该壳体包括适于允许观察针的位置、装置的致动状态以及液体药物的状态中的至少一个的半透明部分。
7.如权利要求2所述的装置，其特征在于，还包括适于容纳压缩气体容器、多个药水瓶以及多个活塞的壳体，该壳体包括状态指示器。
8.如权利要求2所述的装置，其特征在于，还包括适于容纳压缩气体容器、多个药水瓶以及多个活塞的壳体，该壳体包括适于允许观察针的位置的半透明部分。
9.如权利要求2所述的装置，其特征在于，还包括适于容纳压缩气体容器、多个药水瓶以及多个活塞的壳体，该壳体包括气体逸出口。
10.如权利要求2所述的装置，其特征在于，还包括适于放出压缩气体容器中的内容物的致动部分的致动器。
11.如权利要求2所述的装置，其特征在于，还包括适于迫使压缩气体容器进入穿孔器内的弹簧助力致动器。
12.如权利要求2所述的装置，其特征在于，还包括适于放出压缩气体容器中的内容物的致动部分的阀。
13.如权利要求2所述的装置，其特征在于，还包括适于穿透压缩气体容器的穿孔器。
14.如权利要求2所述的装置，其特征在于，还包括穿孔器，该穿孔器带有适于穿透压缩气体容器的尖。
15.如权利要求2所述的装置，其特征在于，还包括适于引导压缩气体容器中排放的内容物的通道。
16.如权利要求2所述的装置，其特征在于，还包括适于同时移动多个活塞中的每一个的推进器。
17.如权利要求2所述的装置，其特征在于，还包括适于响应通过压缩气体容器中排放的内容物提供的压力而同时移动多个活塞中的每一个的推进器。
18.如权利要求2所述的装置，其特征在于，还包括适于使针缩进的弹簧。
19.如权利要求2所述的装置，其特征在于，还包括适于在喷射压力施加在多个药水瓶中的至少一个内的液体药物上时破裂的易碎物。
20.如权利要求2所述的装置，其特征在于，还包括适于防止压缩气体容器中的内容物的致动部分无意中放出的可释放致动锁。
21.如权利要求2所述的装置，其特征在于，还包括适于使压缩气体容器中排放的内容物远离多个活塞排空的气体排空机构。
22.一种具有多个动作的方法，包括：
放出压缩气体容器中的内容物的致动部分，所述压缩气体容器容纳在装置中；
响应所述放出动作，在药水瓶内移动活塞，该药水瓶是容纳在装置内的多个药水瓶中的一个，每个药水瓶适于存储液体药物，每个药水瓶限定了纵向轴线，多个药水瓶的这些纵向轴线平行并且非同轴，多个药水瓶与气体容器中的内容物流体偶联；以及
传送药水瓶中的液体药物并使其穿过可以伸入患者体内的针。
23.如权利要求22所述的方法，其特征在于，还包括释放装置的致动锁。
24.如权利要求22所述的方法，其特征在于，还包括使装置包含的穿孔器致动。
25.如权利要求22所述的方法，其特征在于，还包括穿透压缩气体容器。
26.如权利要求22所述的方法，其特征在于，还包括在喷射压力施加在药水瓶中的液体药物上时使易碎物破裂。
27.如权利要求22所述的方法，其特征在于，还包括使针从装置中伸出。
28.如权利要求22所述的方法，其特征在于，还包括向患者体内注射针中的液体药物。
29.如权利要求22所述的方法，其特征在于，还包括排出压缩气体容器中的内容物的剩余部分。
30.如权利要求22所述的方法，其特征在于，还包括使针缩进到装置内。
31.如权利要求22所述的方法，其特征在于，还包括指示装置的状态。
32.一种装置，包括：
压缩气体容器；
适于放出压缩气体容器中的内容物的致动部分的致动器；
适于存储液体药物的药水瓶，所述药水瓶限定了与致动器的纵向轴线非同轴的纵向轴线，所述药水瓶与气体容器中的内容物的致动部分流体偶联；
适于在药水瓶内移动的活塞，该活塞适于响应压缩气体容器中的内容物的致动部分的放出而传送药水瓶中的液体药物并使其穿过单个针；以及
适于容纳压缩气体容器、药水瓶以及活塞的壳体，该壳体限定了大致与信用卡相等的长度和宽度以及小于一英寸的厚度。

Claims (31)

1.一种装置，包括：
压缩气体容器；
适于放出压缩气体容器中的内容物的致动部分的致动器；
多个适于存储液体药物的药水瓶，每个药水瓶限定了纵向轴线，多个药水瓶的这些纵向轴线平行并且非同轴，多个药水瓶与气体容器中的内容物的致动部分流体偶联；
多个活塞，每个活塞适于在多个药水瓶中的相应药水瓶内移动，多个活塞适于响应压缩气体容器中的内容物的致动部分的放出而传送多个药水瓶中的液体药物并使其穿过单个针；以及
适于容纳压缩气体容器、多个药水瓶以及多个活塞的壳体，该壳体限定了大致与信用卡相等的长度和宽度以及小于一英寸的厚度。
2.一种装置，包括：
压缩气体容器；
多个适于存储液体药物的药水瓶，每个药水瓶限定了纵向轴线，多个药水瓶的这些纵向轴线平行并且非同轴，多个药水瓶与气体容器中的内容物的致动部分流体偶联；以及
多个活塞，每个活塞适于在多个药水瓶中的相应药水瓶内移动，多个活塞适于响应压缩气体容器中的内容物的致动部分的放出而传送多个药水瓶中的至少一部分液体药物并使其穿过可以伸入到患者体内的针。
3.如权利要求2所述的装置，其特征在于，还包括多个适于向针输送多个药水瓶中的至少一部分药物的通道。
4.如权利要求2所述的装置，其特征在于，还包括适于容纳压缩气体容器、多个药水瓶和多个活塞的壳体。
5.如权利要求2所述的装置，其特征在于，还包括适于容纳压缩气体容器、多个药水瓶以及多个活塞的壳体，该壳体限定了大致与信用卡相等的长度和宽度以及小于一英寸的厚度。
6.如权利要求2所述的装置，其特征在于，还包括适于容纳压缩气体容器、多个药水瓶以及多个活塞的壳体，该壳体包括适于允许观察针的位置、装置的致动状态以及液体药物的状态中的至少一个的半透明部分。
7.如权利要求2所述的装置，其特征在于，还包括适于容纳压缩气体容器、多个药水瓶以及多个活塞的壳体，该壳体包括状态指示器。
8.如权利要求2所述的装置，其特征在于，还包括适于容纳压缩气体容器、多个药水瓶以及多个活塞的壳体，该壳体包括适于允许观察针的位置的半透明部分。
9.如权利要求2所述的装置，其特征在于，还包括适于容纳压缩气体容器、多个药水瓶以及多个活塞的壳体，该壳体包括气体选出口。
10.如权利要求2所述的装置，其特征在于，还包括适于放出压缩气体容器中的内容物的致动部分的致动器。
11.如权利要求2所述的装置，其特征在于，还包括适于迫使压缩气体容器进入穿孔器内的弹簧助力致动器。
12.如权利要求2所述的装置，其特征在于，还包括适于放出压缩气体容器中的内容物的致动部分的阀。
13.如权利要求2所述的装置，其特征在于，还包括适于穿透压缩气体容器的穿孔器。
14.如权利要求2所述的装置，其特征在于，还包括穿孔器，该穿孔器带有适于穿透压缩气体容器的尖。
15.如权利要求2所述的装置，其特征在于，还包括适于引导压缩气体容器中排放的内容物的通道。
16.如权利要求2所述的装置，其特征在于，还包括适于同时移动多个活塞中的每一个的推进器。
17.如权利要求2所述的装置，其特征在于，还包括适于响应通过压缩气体容器中排放的内容物提供的压力而同时移动多个活塞中的每一个的推进器。
18.如权利要求2所述的装置，其特征在于，还包括适于使针缩进的弹簧。
19.如权利要求2所述的装置，其特征在于，还包括适于在喷射压力施加在多个药水瓶中的至少一个内的液体药物上时破裂的易碎物。
20.如权利要求2所述的装置，其特征在于，还包括适于防止压缩气体容器中的内容物的致动部分无意中放出的可释放致动锁。
21.如权利要求2所述的装置，其特征在于，还包括适于使压缩气体容器中排放的内容物远离多个活塞排空的气体排空机构。
22.一种具有多个动作的方法，包括：
放出压缩气体容器中的内容物的致动部分，所述压缩气体容器容纳在装置中；
响应所述放出动作，在药水瓶内移动活塞，该药水瓶是容纳在装置内的多个药水瓶中的一个，每个药水瓶适于存储液体药物，每个药水瓶限定了纵向轴线，多个药水瓶的这些纵向轴线平行并且非同轴，多个药水瓶与气体容器中的内容物流体偶联；以及
传送药水瓶中的液体药物并使其穿过可以伸入患者体内的针。
23.如权利要求22所述的方法，其特征在于，还包括释放装置的致动锁。
24.如权利要求22所述的方法，其特征在于，还包括使装置包含的穿孔器致动。
25.如权利要求22所述的方法，其特征在于，还包括穿透压缩气体容器。
26.如权利要求22所述的方法，其特征在于，还包括在喷射压力施加在药水瓶中的液体药物上时使易碎物破裂。
27.如权利要求22所述的方法，其特征在于，还包括使针从装置中伸出。
28.如权利要求22所述的方法，其特征在于，还包括向患者体内注射针中的液体药物。
29.如权利要求22所述的方法，其特征在于，还包括排出压缩气体容器中的内容物的剩余部分。
30.如权利要求22所述的方法，其特征在于，还包括使针缩进到装置内。
31.如权利要求22所述的方法，其特征在于，还包括指示装置的状态。
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CN109125861B (zh) * 2012-04-13 2020-12-29 贝克顿·迪金森公司 用于输送流体的装置
CN107835700A (zh) * 2015-06-30 2018-03-23 Kaleo公司 用于施用在预填充针筒内的药剂的自动注射器
CN113301933A (zh) * 2019-01-24 2021-08-24 伊莱利利公司 鼻腔药品输送装置
CN113301933B (zh) * 2019-01-24 2023-08-22 伊莱利利公司 鼻腔药品输送装置

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