CN100411622C - 由麦角甾醇衍生物制成的黑色素生成抑制剂和美白剂及含有麦角甾醇衍生物的组合物 - Google Patents
由麦角甾醇衍生物制成的黑色素生成抑制剂和美白剂及含有麦角甾醇衍生物的组合物 Download PDFInfo
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- CN100411622C CN100411622C CNB018170145A CN01817014A CN100411622C CN 100411622 C CN100411622 C CN 100411622C CN B018170145 A CNB018170145 A CN B018170145A CN 01817014 A CN01817014 A CN 01817014A CN 100411622 C CN100411622 C CN 100411622C
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- ergosterol derivative
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- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
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- Bioinformatics & Cheminformatics (AREA)
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- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Non-Alcoholic Beverages (AREA)
- Steroid Compounds (AREA)
Abstract
Description
熊果苷 | 式(1) | |
最小抑制浓度 | 0.88μg/mL | 0.045μg/mL |
试验化合物 | 配比量(重量%) | 效果 | |
实施例2 | 式(1) | 0.2 | ○ |
实施例3 | 式(1) | 1.0 | ◎ |
比较例1 | 没添加 | - | × |
比较例2 | 对苯二酚 | 1.0 | △ |
Claims (4)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP310290/2000 | 2000-10-11 | ||
JP2000310290A JP4115656B2 (ja) | 2000-10-11 | 2000-10-11 | エルゴステロール誘導体からなるメラニン生成抑制剤及び美白剤 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1468086A CN1468086A (zh) | 2004-01-14 |
CN100411622C true CN100411622C (zh) | 2008-08-20 |
Family
ID=18790280
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB018170145A Expired - Fee Related CN100411622C (zh) | 2000-10-11 | 2001-10-10 | 由麦角甾醇衍生物制成的黑色素生成抑制剂和美白剂及含有麦角甾醇衍生物的组合物 |
Country Status (9)
Country | Link |
---|---|
US (2) | US20030190299A1 (zh) |
EP (1) | EP1330999B1 (zh) |
JP (1) | JP4115656B2 (zh) |
KR (2) | KR100951390B1 (zh) |
CN (1) | CN100411622C (zh) |
AT (1) | ATE381919T1 (zh) |
DE (1) | DE60132102T2 (zh) |
HK (1) | HK1061970A1 (zh) |
WO (1) | WO2002030366A1 (zh) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
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JPWO2003047593A1 (ja) * | 2001-12-05 | 2005-04-14 | 株式会社坂本バイオ | エルゴステロール誘導体からなるメラニン生成抑制剤及び美白剤、並びにエルゴステロール誘導体を含有する組成物 |
JP4786127B2 (ja) * | 2002-07-12 | 2011-10-05 | 任康 高田 | 色素沈着改善治療薬 |
EP1691199B1 (en) * | 2003-10-01 | 2009-04-01 | Shiseido Company Limited | Method of predicting spot formation on the skin with the use of spot site-accelerating genes as indication and method of screening inhibitor for spot formation on the skin |
KR100559263B1 (ko) * | 2004-08-31 | 2006-03-15 | 한국생명공학연구원 | 표고버섯으로부터 에르고스테롤 에폭사이드 및생리학적으로 허용되는 이의 염을 제조하는 방법 |
RU2477635C1 (ru) * | 2012-02-14 | 2013-03-20 | Глеб Иванович Кирьянов | Способ получения инцистерола |
KR102142314B1 (ko) * | 2013-06-24 | 2020-08-10 | (주)아모레퍼시픽 | 백화고 유래의 에르고스테롤을 포함하는 피부 외용제 조성물 |
CN105338957B (zh) * | 2013-06-24 | 2018-08-17 | 株式会社爱茉莉太平洋 | 包含来源于白花菇的麦角甾醇的皮肤外用剂组合物 |
KR102131176B1 (ko) * | 2013-06-24 | 2020-07-07 | (주)아모레퍼시픽 | 백화고 유래의 에르고스테롤을 포함하는 피부 외용제 조성물 |
TWI507390B (zh) * | 2013-08-01 | 2015-11-11 | Lee Ching Kuo | 藁本中抑制黑色素生成之成分 |
KR20230158140A (ko) * | 2022-05-10 | 2023-11-20 | 한국핵융합에너지연구원 | 플라즈마 처리된 에르고스테롤 반응물의 제조방법, 상기 제조방법으로 제조된 반응물, 이로부터 분리된 화합물 및 이의 용도 |
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JPH07316035A (ja) * | 1994-03-31 | 1995-12-05 | Usuki Seiyaku Kk | 皮膚外用剤 |
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JPH049321A (ja) * | 1990-04-27 | 1992-01-14 | Sunstar Inc | 美白化粧料 |
JPH05317016A (ja) * | 1992-05-15 | 1993-12-03 | Tanabe Seiyaku Co Ltd | 天然酸化防止剤 |
AU9733698A (en) * | 1997-10-24 | 1999-05-17 | Institute Of Materia Medica Chinese Academy Of Medical Sciences | Process for making and uses of cordyceps fermentation products |
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- 2001-10-10 EP EP01974762A patent/EP1330999B1/en not_active Expired - Lifetime
- 2001-10-10 US US10/399,029 patent/US20030190299A1/en not_active Abandoned
- 2001-10-10 KR KR1020087013188A patent/KR100951390B1/ko active IP Right Grant
- 2001-10-10 WO PCT/JP2001/008892 patent/WO2002030366A1/ja active IP Right Grant
- 2001-10-10 CN CNB018170145A patent/CN100411622C/zh not_active Expired - Fee Related
- 2001-10-10 KR KR10-2003-7005104A patent/KR20030074606A/ko not_active Application Discontinuation
- 2001-10-10 AT AT01974762T patent/ATE381919T1/de not_active IP Right Cessation
- 2001-10-10 DE DE60132102T patent/DE60132102T2/de not_active Expired - Lifetime
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2004
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2008
- 2008-05-28 US US12/128,137 patent/US20080234241A1/en not_active Abandoned
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JPH07316035A (ja) * | 1994-03-31 | 1995-12-05 | Usuki Seiyaku Kk | 皮膚外用剤 |
JP2000136130A (ja) * | 1998-10-30 | 2000-05-16 | Coral Biotech Kk | ヒスタミン遊離抑制剤 |
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Also Published As
Publication number | Publication date |
---|---|
KR100951390B1 (ko) | 2010-04-08 |
KR20030074606A (ko) | 2003-09-19 |
DE60132102T2 (de) | 2008-10-23 |
DE60132102D1 (de) | 2008-02-07 |
WO2002030366A1 (fr) | 2002-04-18 |
JP2002114685A (ja) | 2002-04-16 |
EP1330999A1 (en) | 2003-07-30 |
US20030190299A1 (en) | 2003-10-09 |
US20080234241A1 (en) | 2008-09-25 |
KR20080056323A (ko) | 2008-06-20 |
EP1330999B1 (en) | 2007-12-26 |
CN1468086A (zh) | 2004-01-14 |
ATE381919T1 (de) | 2008-01-15 |
JP4115656B2 (ja) | 2008-07-09 |
EP1330999A4 (en) | 2005-04-27 |
HK1061970A1 (en) | 2004-10-15 |
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