CL2007003523A1 - Compuestos derivados de heterociclos sustituidos con morfolina, inhibidores de la actividad de pi3 quinasa; composicion farmaceutica que comprende a dichos compuestos; kit farmaceutico; y su uso en el tratamiento profilactico o terapeutico del cancer - Google Patents
Compuestos derivados de heterociclos sustituidos con morfolina, inhibidores de la actividad de pi3 quinasa; composicion farmaceutica que comprende a dichos compuestos; kit farmaceutico; y su uso en el tratamiento profilactico o terapeutico del cancerInfo
- Publication number
- CL2007003523A1 CL2007003523A1 CL200703523A CL2007003523A CL2007003523A1 CL 2007003523 A1 CL2007003523 A1 CL 2007003523A1 CL 200703523 A CL200703523 A CL 200703523A CL 2007003523 A CL2007003523 A CL 2007003523A CL 2007003523 A1 CL2007003523 A1 CL 2007003523A1
- Authority
- CL
- Chile
- Prior art keywords
- compounds
- morfolina
- profilactic
- heterocicles
- quinasa
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US87342206P | 2006-12-07 | 2006-12-07 |
Publications (1)
Publication Number | Publication Date |
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CL2007003523A1 true CL2007003523A1 (es) | 2008-08-22 |
Family
ID=39403189
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL200703523A CL2007003523A1 (es) | 2006-12-07 | 2007-12-05 | Compuestos derivados de heterociclos sustituidos con morfolina, inhibidores de la actividad de pi3 quinasa; composicion farmaceutica que comprende a dichos compuestos; kit farmaceutico; y su uso en el tratamiento profilactico o terapeutico del cancer |
Country Status (19)
Country | Link |
---|---|
US (1) | US9487533B2 (es) |
EP (1) | EP2114950B1 (es) |
JP (1) | JP5500990B2 (es) |
KR (1) | KR101507182B1 (es) |
CN (1) | CN101675053B (es) |
AR (1) | AR064154A1 (es) |
AU (1) | AU2007333243B2 (es) |
BR (1) | BRPI0717907A2 (es) |
CA (1) | CA2671845C (es) |
CL (1) | CL2007003523A1 (es) |
ES (1) | ES2571028T3 (es) |
IL (1) | IL199151A (es) |
MX (1) | MX2009005925A (es) |
NO (1) | NO342697B1 (es) |
PE (1) | PE20081353A1 (es) |
RU (1) | RU2470936C2 (es) |
TW (1) | TW200829594A (es) |
WO (1) | WO2008073785A2 (es) |
ZA (1) | ZA200904531B (es) |
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ES2217956B1 (es) * | 2003-01-23 | 2006-04-01 | Almirall Prodesfarma, S.A. | Nuevos derivados de 4-aminotieno(2,3-d)pirimidin-6-carbonitrilo. |
CN1960809B (zh) * | 2004-06-03 | 2010-10-13 | 诺信公司 | 一种粉末涂料系统 |
EP1806347A4 (en) * | 2004-10-08 | 2009-07-01 | Astellas Pharma Inc | PYRIMIDINE DERIVATIVES FUSED WITH AN AROMATIC RING |
GB0423653D0 (en) * | 2004-10-25 | 2004-11-24 | Piramed Ltd | Pharmaceutical compounds |
WO2007127175A2 (en) * | 2006-04-26 | 2007-11-08 | F. Hoffmann-La Roche Ag | Pharmaceutical compounds |
BRPI0710866A2 (pt) | 2006-04-26 | 2012-08-14 | Hoffmann La Roche | compostos farmacÊuticos |
CL2007001165A1 (es) * | 2006-04-26 | 2008-01-25 | Hoffmann La Roche | 2-(1h-indazol-4-il)-6-(4-metanosulfonil-piperazin-1-ilmetil)-4-morfolin-4-il-tieno[3,2-d]pirimidina; procedimiento de preparacion; composicion farmaceutica; proceso de preparacion de dicha composicion; kit farmaceutico; y uso para tratar enfermedades tales como cancer, desordenes inmunes y enfermedades cardiovasculares. |
AR060632A1 (es) * | 2006-04-26 | 2008-07-02 | Genentech Inc | Compuestos inhibidores de fosfoinositida 3- quinasa y metodos de uso |
GB0608820D0 (en) | 2006-05-04 | 2006-06-14 | Piramed Ltd | Pharmaceutical compounds |
CA2671782C (en) | 2006-12-07 | 2017-01-10 | F. Hoffmann-La Roche Ag | Phosphoinositide 3-kinase inhibitor compounds and methods of use |
-
2007
- 2007-12-05 RU RU2009125916/04A patent/RU2470936C2/ru not_active IP Right Cessation
- 2007-12-05 ES ES07865255T patent/ES2571028T3/es active Active
- 2007-12-05 EP EP07865255.9A patent/EP2114950B1/en active Active
- 2007-12-05 TW TW096146408A patent/TW200829594A/zh unknown
- 2007-12-05 AR ARP070105448A patent/AR064154A1/es unknown
- 2007-12-05 CN CN200780051049.8A patent/CN101675053B/zh active Active
- 2007-12-05 CL CL200703523A patent/CL2007003523A1/es unknown
- 2007-12-05 CA CA2671845A patent/CA2671845C/en not_active Expired - Fee Related
- 2007-12-05 ZA ZA200904531A patent/ZA200904531B/xx unknown
- 2007-12-05 US US11/951,189 patent/US9487533B2/en active Active
- 2007-12-05 PE PE2007001727A patent/PE20081353A1/es not_active Application Discontinuation
- 2007-12-05 MX MX2009005925A patent/MX2009005925A/es active IP Right Grant
- 2007-12-05 KR KR1020097014132A patent/KR101507182B1/ko active IP Right Grant
- 2007-12-05 BR BRPI0717907-3A2A patent/BRPI0717907A2/pt not_active Application Discontinuation
- 2007-12-05 WO PCT/US2007/086533 patent/WO2008073785A2/en active Application Filing
- 2007-12-05 AU AU2007333243A patent/AU2007333243B2/en not_active Ceased
- 2007-12-05 JP JP2009540457A patent/JP5500990B2/ja active Active
-
2009
- 2009-06-04 IL IL199151A patent/IL199151A/en not_active IP Right Cessation
- 2009-07-06 NO NO20092565A patent/NO342697B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ZA200904531B (en) | 2010-09-29 |
AU2007333243A1 (en) | 2008-06-19 |
KR20090106508A (ko) | 2009-10-09 |
TW200829594A (en) | 2008-07-16 |
IL199151A0 (en) | 2010-03-28 |
US9487533B2 (en) | 2016-11-08 |
RU2009125916A (ru) | 2011-01-20 |
CA2671845C (en) | 2015-03-24 |
WO2008073785A2 (en) | 2008-06-19 |
JP5500990B2 (ja) | 2014-05-21 |
PE20081353A1 (es) | 2008-11-12 |
NO342697B1 (no) | 2018-07-09 |
AU2007333243B2 (en) | 2013-03-14 |
ES2571028T3 (es) | 2016-05-23 |
NO20092565L (no) | 2009-09-07 |
JP2010512337A (ja) | 2010-04-22 |
IL199151A (en) | 2017-01-31 |
CA2671845A1 (en) | 2008-06-19 |
RU2470936C2 (ru) | 2012-12-27 |
EP2114950B1 (en) | 2016-03-09 |
KR101507182B1 (ko) | 2015-03-30 |
BRPI0717907A2 (pt) | 2013-11-05 |
EP2114950A2 (en) | 2009-11-11 |
CN101675053A (zh) | 2010-03-17 |
AR064154A1 (es) | 2009-03-18 |
MX2009005925A (es) | 2009-08-12 |
WO2008073785A3 (en) | 2008-08-28 |
CN101675053B (zh) | 2014-03-12 |
US20080269210A1 (en) | 2008-10-30 |
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